sulfaphenazole has been researched along with Injury, Myocardial Reperfusion in 7 studies
Sulfaphenazole: A sulfonilamide anti-infective agent.
sulfaphenazole : A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, SPZ treatment showed significantly decreased superoxide levels and enhanced NO bioavailability in the reperfused heart." | 1.34 | Cardioprotection by sulfaphenazole, a cytochrome p450 inhibitor: mitigation of ischemia-reperfusion injury by scavenging of reactive oxygen species. ( Khan, M; Kumbala, D; Kuppusamy, P; Kutala, VK; Mohan, IK, 2007) |
| "Chloramphenicol is an inhibitor of mitochondrial protein synthesis and is also an inhibitor of a subset of cytochrome P450 monooxygenases (CYPs)." | 1.32 | Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. ( Gottlieb, RA; Granville, DJ; Gustafsson, AB; Huang, C; Sayen, MR; Takeuchi, C; Tashakkor, B; Wentworth, P; Yeager, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hunter, AL | 1 |
| Kerjner, A | 1 |
| Mueller, KJ | 1 |
| McManus, BM | 1 |
| Granville, DJ | 2 |
| Ishihara, Y | 3 |
| Sekine, M | 2 |
| Nakazawa, M | 2 |
| Shimamoto, N | 3 |
| Huang, C | 2 |
| Liu, W | 1 |
| Perry, CN | 1 |
| Yitzhaki, S | 1 |
| Lee, Y | 1 |
| Yuan, H | 1 |
| Tsukada, YT | 1 |
| Hamacher-Brady, A | 1 |
| Mentzer, RM | 1 |
| Gottlieb, RA | 2 |
| Hamaguchi, A | 1 |
| Kobayashi, Y | 1 |
| Harayama, T | 1 |
| Tashakkor, B | 1 |
| Takeuchi, C | 1 |
| Gustafsson, AB | 1 |
| Sayen, MR | 1 |
| Wentworth, P | 1 |
| Yeager, M | 1 |
| Khan, M | 1 |
| Mohan, IK | 1 |
| Kutala, VK | 1 |
| Kumbala, D | 1 |
| Kuppusamy, P | 1 |
7 other studies available for sulfaphenazole and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Cytochrome p450 2C enzymes contribute to peritransplant ischemic injury and cardiac allograft vasculopathy.
Topics: Animals; Anti-Infective Agents; Cell Proliferation; Coronary Vessels; Cytochrome P-450 Enzyme System | 2008 |
Suppression of myocardial ischemia-reperfusion injury by inhibitors of cytochrome P450 in rats.
Topics: Animals; Body Weight; Cimetidine; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhib | 2009 |
Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole.
Topics: Adenoviridae; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Autophagy; Autophagy-Related Pr | 2010 |
Effects of sulfaphenazole derivatives on cardiac ischemia-reperfusion injury: association of cytochrome P450 activity and infarct size.
Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Electron Spin Resonan | 2010 |
Sulfaphenazole attenuates myocardial cell apoptosis accompanied with cardiac ischemia-reperfusion by suppressing the expression of BimEL and Noxa.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Caspase 3; Caspase 7; Cyto | 2012 |
Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors.
Topics: Animals; Chloramphenicol; Cimetidine; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrom | 2004 |
Cardioprotection by sulfaphenazole, a cytochrome p450 inhibitor: mitigation of ischemia-reperfusion injury by scavenging of reactive oxygen species.
Topics: Animals; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Free Radical Scaven | 2007 |