sulfaphenazole has been researched along with Hyperuricemia in 2 studies
Sulfaphenazole: A sulfonilamide anti-infective agent.
sulfaphenazole : A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
Hyperuricemia: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lesinurad is a uricosuric agent for the treatment of hyperuricemia associated with gout, which was found lacking in efficacy and safety." | 4.12 | Discovery of Novel Bicyclic Imidazolopyridine-Containing Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Improved Efficacy and Favorable Druggability. ( Ji, J; Liang, R; Liao, H; Liu, X; Pang, J; Shi, X; Tao, Y; Wu, T; Zhan, P; Zhang, J; Zhang, Z; Zhao, F; Zhao, T, 2022) |
| "Lesinurad, a human urate transporter 1 (URAT1) inhibitor approved as a medication for the treatment of hyperuricemia associated with gout in 2015, can cause liver and renal toxicity." | 3.96 | Novel Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Favorable Druggability. ( Ai, W; Chen, Y; Dong, Y; Kang, D; Liang, R; Liu, X; Meng, Q; Pang, J; Sun, Z; Wu, T; Zhan, P; Zhao, T; Zhao, Z, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, T | 2 |
| Meng, Q | 1 |
| Sun, Z | 1 |
| Chen, Y | 1 |
| Ai, W | 1 |
| Zhao, Z | 1 |
| Kang, D | 1 |
| Dong, Y | 1 |
| Liang, R | 2 |
| Wu, T | 2 |
| Pang, J | 2 |
| Liu, X | 2 |
| Zhan, P | 2 |
| Zhang, J | 1 |
| Tao, Y | 1 |
| Liao, H | 1 |
| Zhao, F | 1 |
| Shi, X | 1 |
| Zhang, Z | 1 |
| Ji, J | 1 |
2 other studies available for sulfaphenazole and Hyperuricemia
| Article | Year |
|---|---|
Novel Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Favorable Druggability.
Topics: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Gout; HEK293 Cells; Humans; Hyperuricemia; Mass | 2020 |
Discovery of Novel Bicyclic Imidazolopyridine-Containing Human Urate Transporter 1 Inhibitors as Hypouricemic Drug Candidates with Improved Efficacy and Favorable Druggability.
Topics: Animals; Gout; Humans; Hyperuricemia; Mice; Organic Anion Transporters; Organic Cation Transport Pro | 2022 |