sulfaphenazole has been researched along with Diabetes Mellitus, Adult-Onset in 2 studies
Sulfaphenazole: A sulfonilamide anti-infective agent.
sulfaphenazole : A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report for the first time that CYP 2C inhibition reduces oxidative stress (measured as plasma levels of 8-isoprostane), increases NO bioavailability (measured as NO(2)(-)) and restores endothelial function in db/db mice without affecting plasma glucose levels." | 1.35 | Sulfaphenazole treatment restores endothelium-dependent vasodilation in diabetic mice. ( Elmi, S; Granville, DJ; Hunter, AL; Khazaei, M; Laher, I; Moien-Afshari, F; Rahman, MM; Sallam, NA; Teng, X, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, H | 1 |
| Kold-Petersen, H | 1 |
| Laher, I | 2 |
| Simonsen, U | 1 |
| Aalkjaer, C | 1 |
| Elmi, S | 1 |
| Sallam, NA | 1 |
| Rahman, MM | 1 |
| Teng, X | 1 |
| Hunter, AL | 1 |
| Moien-Afshari, F | 1 |
| Khazaei, M | 1 |
| Granville, DJ | 1 |
2 other studies available for sulfaphenazole and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Impaired endothelial calcium signaling is responsible for the defective dilation of mesenteric resistance arteries from db/db mice to acetylcholine.
Topics: Acetylcholine; Animals; Calcium Signaling; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System | 2015 |
Sulfaphenazole treatment restores endothelium-dependent vasodilation in diabetic mice.
Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Biomarkers; Blood Glucose; Cyclic N-Oxides; C | 2008 |