Page last updated: 2024-11-04

sulfaphenazole and Breast Cancer

sulfaphenazole has been researched along with Breast Cancer in 3 studies

Sulfaphenazole: A sulfonilamide anti-infective agent.
sulfaphenazole : A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.

Research Excerpts

ExcerptRelevanceReference
" Compound 3 administered orally reached peak concentration of nearly 40 μM with a half-life of about 2 h."1.37Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis. ( Jo, I; Jones, DR; Khanna, M; Knabe, WE; Li, J; Li, L; Meroueh, SO; Nakshatri, H; Oh, K; Pollok, KE; Sandusky, GE; Silver, JM; Sinn, AL; Sledge, GW; Wang, F, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Wang, F1
Li, J1
Sinn, AL1
Knabe, WE1
Khanna, M1
Jo, I1
Silver, JM1
Oh, K1
Li, L1
Sandusky, GE1
Sledge, GW1
Nakshatri, H1
Jones, DR1
Pollok, KE1
Meroueh, SO1
Sun, Y3
Wang, L1
Wu, T1
Yin, W1
Wang, J1
Xue, Y1
Qin, Q1
Yang, H1
Zhao, D1
Cheng, M1
Eissa, AG1
Barrow, D1
Gee, J1
Powell, LE1
Foster, PA1
Simons, C1

Other Studies

3 other studies available for sulfaphenazole and Breast Cancer

ArticleYear
Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis.
    Journal of medicinal chemistry, 2011, Oct-27, Volume: 54, Issue:20

    Topics: Angiogenesis Inhibitors; Anilides; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell

2011
Design, synthesis, and biological evaluation of novel pyrazolo [3,4-d]pyrimidine derivatives as potent PLK4 inhibitors for the treatment of TRIM37-amplified breast cancer.
    European journal of medicinal chemistry, 2022, Aug-05, Volume: 238

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Design;

2022
4th generation nonsteroidal aromatase inhibitors: An iterative SAR-guided design, synthesis, and biological evaluation towards picomolar dual binding inhibitors.
    European journal of medicinal chemistry, 2022, Oct-05, Volume: 240

    Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Receptors, Estrogen; Triazoles

2022