sulfaphenazole has been researched along with Brain Edema in 1 studies
Sulfaphenazole: A sulfonilamide anti-infective agent.
sulfaphenazole : A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfaphenazole (SPZ) has a different mechanism such as reactive oxygen species scavenging, in addition to the inhibition of superoxide production by cytochrome P450." | 5.38 | Effects of sulfaphenazole after collagenase-induced experimental intracerebral hemorrhage in rats. ( Danjo, S; Hama, S; Ishihara, Y; Itoh, K; Nakamura, Y; Watanabe, M, 2012) |
| "Sulfaphenazole (SPZ) has a different mechanism such as reactive oxygen species scavenging, in addition to the inhibition of superoxide production by cytochrome P450." | 1.38 | Effects of sulfaphenazole after collagenase-induced experimental intracerebral hemorrhage in rats. ( Danjo, S; Hama, S; Ishihara, Y; Itoh, K; Nakamura, Y; Watanabe, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hama, S | 1 |
| Ishihara, Y | 1 |
| Watanabe, M | 1 |
| Danjo, S | 1 |
| Nakamura, Y | 1 |
| Itoh, K | 1 |
1 other study available for sulfaphenazole and Brain Edema
| Article | Year |
|---|---|
Effects of sulfaphenazole after collagenase-induced experimental intracerebral hemorrhage in rats.
Topics: Animals; Behavior, Animal; Brain Edema; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; L | 2012 |