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sulfamethoxazole and Toxoplasmosis, Animal

sulfamethoxazole has been researched along with Toxoplasmosis, Animal in 26 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Toxoplasmosis, Animal: Acquired infection of non-human animals by organisms of the genus TOXOPLASMA.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the effects of sulfamethoxazole (SMX) on experimental ocular toxoplasmosis by quantitative competitive polymerase chain reaction (QC-PCR) assay."7.73Effects of sulfamethoxazole on murine ocular toxoplasmosis in interferon-gamma knockout mice. ( Aosai, F; Mun, HS; Norose, K; Yano, A, 2006)
"To evaluate the effects of sulfamethoxazole (SMX) on experimental ocular toxoplasmosis by quantitative competitive polymerase chain reaction (QC-PCR) assay."3.73Effects of sulfamethoxazole on murine ocular toxoplasmosis in interferon-gamma knockout mice. ( Aosai, F; Mun, HS; Norose, K; Yano, A, 2006)
"To evaluate the effect of allicin alone or combined with SMZco on murine toxoplasmosis by a specific, rapid, and sensitive PCR technique."1.32[PCR in evaluating the effect of allicin and its combination with SMZco on murine toxoplamosis]. ( Liu, PM; Shan, LY; Yang, XZ, 2003)
" Extending these experiments, we have now shown that roxithromycin at doses of 400 or 200 mg/kg/day combined with dapsone at doses of 5, 25 or 50 mg/kg/day completely prevented the development of T."1.30Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model. ( Brun-Pascaud, M; Chau, F; Derouin, F; Girard, PM, 1998)
"Treatment with pyrimethamine and sulfamethoxazolum combination administered via intragastric route, was started 2 hours after each mouse received an intraperitoneal injection of a lethal inoculum of 5 x 10(3) tachyzoites of RH strain toxoplasma gondii and the therapy was lasted for 52 days."1.30[Preliminary application of PCR to curative effect assessment of chemotherapy against experimental acute infection of Toxoplasma gondii in mice]. ( Ke, OY; Xiang, X; Zhang, Z, 1997)
" In the chronic cystogenic murine models, the combination TMP plus SMX administered from day 5 for 15 days or from day 28 for 288 days, gave protection and even apparent toxoplasmal eradication ('cure') at the highest dosing (60/300 mg/kg per day)."1.30Evaluation of trimethoprim and sulphamethoxazole as monotherapy or in combination in the management of toxoplasmosis in murine models. ( Dumas, JL; Pechère, JC; Pizzolato, G, 1999)
"Five drug regimens for the treatment of acute toxoplasmosis were compared in a monkey model."1.27Five drug regimens for treatment of acute toxoplasmosis in squirrel monkeys. ( Harper, JS; London, WT; Sever, JL, 1985)
" By the suitable dosage the mortality rate could be reduced considerably."1.26[Experimental studies on the effect of the combination sulfamoxole/trimethoprim on the Toxoplasma infection of the mouse (author's transl)]. ( Maier, W; Piekarski, G, 1976)
"Trimethoprim was found to have no effect."1.25Chemotherapy in experimental toxoplasmosis: comparison of the efficacy of trimethoprim-sulfur and pyrimethamine-sulfur combinations. ( Seah, SK, 1975)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199017 (65.38)18.7374
1990's4 (15.38)18.2507
2000's4 (15.38)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belal, US2
Norose, K3
Mohamed, RM2
Sekine, S1
Nukaga, T1
Ito, K1
Abdellatif, MZ1
Abdelgelil, NH1
Yano, A3
Shan, LY1
Yang, XZ1
Liu, PM1
Aosai, F2
Mun, HS2
Ahmed, AK1
Chen, M1
Piao, LX1
Iwakura, Y1
Fiorello, CV1
Heard, DJ1
Heller, HL1
Russell, K1
Nguyen, BT3
Stadtsbaeder, S4
Garin, JP1
Paillard, B1
Alder, J1
Hutch, T1
Meulbroek, JA1
Clement, JC1
Brun-Pascaud, M1
Chau, F1
Derouin, F1
Girard, PM1
Xiang, X1
Ke, OY1
Zhang, Z1
Dumas, JL1
Pizzolato, G1
Pechère, JC1
Grossman, PL1
Remington, JS2
Thiermann, E1
Apt, W1
Atias, A1
Lorca, M1
Olguín, J1
Coradello, H1
Kretschmer, S1
Maier, W1
Piekarski, G1
Seah, SK1
Hamadto, HH1
Rashed, SM1
Marii, NE1
Sobhy, MM1
el-Ridi, AM1
el-Fakahany, AF1
Harper, JS1
London, WT1
Sever, JL1
Vischer, WA1
Terragna, A1
Rossolini, A1
Cellesi, C1
Figura, N1
Barberi, A1
Calvin-Preval, MC1
Sander, J2
Midtvedt, T2

Other Studies

26 other studies available for sulfamethoxazole and Toxoplasmosis, Animal

ArticleYear
Quantitative assessment of the effects of sulfamethoxazole on Toxoplasma gondii loads in susceptible WT C57BL/6 mice as an immunocompetent host model.
    Parasitology international, 2016, Volume: 65, Issue:1

    Topics: Animals; Brain; Coccidiostats; Disease Models, Animal; DNA, Protozoan; Heart; Immunocompetence; Lung

2016
[PCR in evaluating the effect of allicin and its combination with SMZco on murine toxoplamosis].
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2003, Volume: 21, Issue:4

    Topics: Animals; Anti-Infective Agents; Disulfides; DNA, Protozoan; Drug Synergism; Drug Therapy, Combinatio

2003
Evaluation of the effects of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-gamma knockout mice using QC-PCR.
    Microbiology and immunology, 2004, Volume: 48, Issue:3

    Topics: Animals; Disease Models, Animal; Interferon-gamma; Mice; Mice, Inbred BALB C; Mice, Knockout; Revers

2004
Effects of sulfamethoxazole on murine ocular toxoplasmosis in interferon-gamma knockout mice.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:1

    Topics: Animals; Anti-Infective Agents; Chorioretinitis; DNA, Protozoan; Female; Interferon-gamma; Male; Mic

2006
Medical management of Toxoplasma meningitis in a white-throated capuchin (Cebus capucinus).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2006, Volume: 37, Issue:3

    Topics: Animals; Antiprotozoal Agents; Cebus; Clindamycin; Female; Meningitis; Monkey Diseases; Sulfamethoxa

2006
[Therapeutic future of trimethoprim-sulfamethoxazole in toxoplasmosis].
    Presse medicale (Paris, France : 1983), 1983, Feb-12, Volume: 12, Issue:6

    Topics: Animals; Drug Combinations; Female; Humans; Mice; Pregnancy; Sulfamethoxazole; Toxoplasmosis; Toxopl

1983
[Experimental toxoplasmosis in mice. Comparative activity of clindamycin, midecamycin, josamycin, spiramycin, pyrimethamine-sulfadoxine, and trimethoprim-sulfamethoxazole].
    Annales de pediatrie, 1984, Volume: 31, Issue:10

    Topics: Animals; Clindamycin; Drug Combinations; Leucomycins; Mice; Pyrimethamine; Sulfadoxine; Sulfamethoxa

1984
Comparative effects of cotrimoxazole (trimethoprim-sulphamethoxazole), pyrimethamine-sulphadiazine and spiramycin during avirulent infection with Toxoplasma gondii (Beverley strain) in mice.
    British journal of pharmacology, 1983, Volume: 79, Issue:4

    Topics: Animals; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Leucomyci

1983
Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:11

    Topics: AIDS-Related Opportunistic Infections; Animals; Clarithromycin; Disease Models, Animal; Dose-Respons

1994
Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41 Suppl B

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Disease Models, Animal; Dose-Respons

1998
[Preliminary application of PCR to curative effect assessment of chemotherapy against experimental acute infection of Toxoplasma gondii in mice].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 1997, Volume: 22, Issue:1

    Topics: Animals; Antiprotozoal Agents; Brain; Drug Therapy, Combination; Female; Mice; Mice, Inbred BALB C;

1997
Evaluation of trimethoprim and sulphamethoxazole as monotherapy or in combination in the management of toxoplasmosis in murine models.
    International journal of antimicrobial agents, 1999, Volume: 13, Issue:1

    Topics: Animals; Chronic Disease; Disease Models, Animal; Drug Evaluation; Mice; Sulfamethoxazole; Toxoplasm

1999
The effect of trimethoprim and sulfamethoxazole on Toxoplasma gondii in vitro and in vivo.
    The American journal of tropical medicine and hygiene, 1979, Volume: 28, Issue:3

    Topics: Administration, Oral; Animals; Culture Techniques; Dose-Response Relationship, Drug; Drug Therapy, C

1979
A comparative study of some combined treatment regimens in acute toxoplasmosis in mice.
    The American journal of tropical medicine and hygiene, 1978, Volume: 27, Issue:4

    Topics: Acute Disease; Animals; Clindamycin; Drug Therapy, Combination; Humans; Leucomycins; Mice; Pyrimetha

1978
[A comparison of Ultrax, Diazil, Bactrim and Spiramycin in experimental toxoplasmosis in mice (author's transl)].
    Wiener klinische Wochenschrift, 1978, Jan-06, Volume: 90, Issue:1

    Topics: Animals; Injections, Subcutaneous; Leucomycins; Mice; Pyrimethamine; Sulfameter; Sulfamethazine; Sul

1978
[Experimental studies on the effect of the combination sulfamoxole/trimethoprim on the Toxoplasma infection of the mouse (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:42

    Topics: Animals; Drug Combinations; Mice; Sulfamethoxazole; Sulfamoxole; Toxoplasmosis, Animal; Trimethoprim

1976
Chemotherapy in experimental toxoplasmosis: comparison of the efficacy of trimethoprim-sulfur and pyrimethamine-sulfur combinations.
    The Journal of tropical medicine and hygiene, 1975, Volume: 78, Issue:7

    Topics: Animals; Drug Combinations; Drug Evaluation; Female; Mice; Pyrimethamine; Sulfadiazine; Sulfamethoxa

1975
Trimethoprim-sulfamethoxazole in murine toxoplasmosis.
    Antimicrobial agents and chemotherapy, 1976, Volume: 9, Issue:2

    Topics: Animals; Drug Therapy, Combination; Mice; Sulfamethoxazole; Toxoplasmosis, Animal; Trimethoprim

1976
The effect of some drugs on acute toxoplasmosis in mice.
    Journal of the Egyptian Society of Parasitology, 1989, Volume: 19, Issue:2

    Topics: Animals; Chloroquine; Clindamycin; Drug Combinations; Levamisole; Mice; Praziquantel; Sulfamethoxazo

1989
Comparative effects of cotrimoxazole (trimethoprim-sulphamethoxazole) and spiramycin in pregnant mice infected with Toxoplasma gondii (Beverley strain).
    British journal of pharmacology, 1985, Volume: 85, Issue:3

    Topics: Animals; Antibodies; Birth Weight; Congenital Abnormalities; Delivery, Obstetric; Drug Combinations;

1985
Five drug regimens for treatment of acute toxoplasmosis in squirrel monkeys.
    The American journal of tropical medicine and hygiene, 1985, Volume: 34, Issue:1

    Topics: Animals; Clindamycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leuco

1985
[Comparative study on the effect of some clinically used sulfanilamide derivatives against toxoplasmosis in the mouse].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1973, Volume: 223, Issue:2

    Topics: Aminobenzoates; Animals; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syn

1973
Activity of the combination trimethoprim-sulfamethoxazole on experimental toxoplasmosis.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Animals; Drug Combinations; Fluorescent Antibody Technique; Histocytochemistry; Liver; Mice; Succina

1973
[The trimethoprim-sulfamethoxazole association in experimental toxoplasmosis in mice].
    Acta clinica Belgica, 1973, Volume: 28, Issue:1

    Topics: Animals; Mice; Sulfamethoxazole; Toxoplasmosis, Animal; Trimethoprim

1973
The effect of trimethoprim on acute experimental toxoplasmosis in mice.
    Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology, 1970, Volume: 78, Issue:6

    Topics: Animals; Carrier State; Drug Synergism; Female; Male; Mice; Pyrimidines; Sulfamethoxazole; Time Fact

1970
Development of sulphonamide resistance in Toxoplasma gondii.
    Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology, 1971, Volume: 79, Issue:4

    Topics: Animals; Drug Resistance, Microbial; Female; Male; Mice; Sulfamethoxazole; Toxoplasma; Toxoplasmosis

1971