sulfamethoxazole has been researched along with Symptom Cluster in 6 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypersensitivity syndromes are severe drug induced side effects with skin rashes, fever and/or multiorgan-system abnormalities which are not pharmacologically related." | 2.40 | [Drug-induced hypersensitivity syndrome. A review and presentation of 2 personal cases]. ( Pichler, WJ; Schnyder, B; Zanni, MP, 1997) |
| "If the vasculitis is secondary to an underlying disease, such as lymphoma, therapy should be directed at the primary disease." | 2.37 | Pulmonary vasculitis. ( Fauci, AS; Leavitt, RY, 1986) |
| "The syndrome is characterised by fever, an itchy erythema with edema, confluent papules and purpura of the hands and feet in a "gloves and socks" distribution." | 1.30 | [Drug-induced papular-purpuric gloves and socks syndrome]. ( Ballmer-Weber, BK; Brand, CU; Hunziker, TK; van Rooijen, MM; Yawalkar, N, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nolph, MB | 1 |
| Dion, MW | 1 |
| Schnyder, B | 1 |
| Zanni, MP | 1 |
| Pichler, WJ | 1 |
| van Rooijen, MM | 1 |
| Brand, CU | 1 |
| Ballmer-Weber, BK | 1 |
| Yawalkar, N | 1 |
| Hunziker, TK | 1 |
| Leavitt, RY | 1 |
| Fauci, AS | 1 |
| First, LR | 1 |
| Smith, BR | 1 |
| Lipton, J | 1 |
| Nathan, DG | 1 |
| Parkman, R | 1 |
| Rappeport, JM | 1 |
| Böhm, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Azacitidine (AZA) Combined With N-Acetyl-L-cysteine (NAC) for Prolonged Isolated Thrombocytopenia (PIT) After Hematopoietic Stem Cell Transplantation (HSCT)[NCT05126004] | Phase 2 | 100 participants (Anticipated) | Interventional | 2021-12-01 | Not yet recruiting | ||
| A Prospective Study of Patients With Isolated Thrombocytopenia Following Hematopoietic Stem Cell Transplantation[NCT02487563] | Phase 3 | 97 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The total number of megakaryocytes as well as the platelet-shedding megakaryocytes of bone marrow smears (per cm2) was counted and cross-checked by blinded observers. (NCT02487563)
Timeframe: Up to 4 weeks after the treatment
| Intervention | cells/cm^2 (Median) |
|---|---|
| Experimental Group 1 | 6.7 |
| Experimental Group 2 | 7.5 |
| Control Group | 3.3 |
Platelet response refers to a sustained increase (stable or increasing level) of at least 30×10E9/L independent of transfusion for 3 days. (NCT02487563)
Timeframe: Up to 4 weeks after the treatment
| Intervention | Participants (Count of Participants) |
|---|---|
| Experimental Group 1 | 20 |
| Experimental Group 2 | 22 |
| Control Group | 6 |
2 reviews available for sulfamethoxazole and Symptom Cluster
| Article | Year |
|---|---|
[Drug-induced hypersensitivity syndrome. A review and presentation of 2 personal cases].
Topics: Adult; Aged; Allopurinol; CD8 Antigens; Drug Eruptions; Drug Hypersensitivity; Female; HLA-DR Antige | 1997 |
Pulmonary vasculitis.
Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Chlorambucil; Connective Tissue Diseases; Cy | 1986 |
4 other studies available for sulfamethoxazole and Symptom Cluster
| Article | Year |
|---|---|
Raeder's syndrome associated with internal carotid artery dilation and sinusitis.
Topics: Adult; Carotid Artery Diseases; Carotid Artery, Internal; Dilatation, Pathologic; Facial Neuralgia; | 1982 |
[Drug-induced papular-purpuric gloves and socks syndrome].
Topics: Aged; Edema; Erythema; Foot Dermatoses; Hand Dermatoses; Humans; Male; Pruritus; Purpura; Skin Disea | 1999 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
[Attack prevention and exacerbation therapy of the chronic bronchitis syndrome].
Topics: Adult; Age Factors; Aged; Anti-Bacterial Agents; Bronchitis; Chronic Disease; Disability Evaluation; | 1974 |