sulfamethoxazole and Prostatitis studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Prostatitis: Infiltration of inflammatory cells into the parenchyma of PROSTATE. The subtypes are classified by their varied laboratory analysis, clinical presentation and response to treatment.

Research Excerpts

Excerpt	Relevance	Reference
"A comparative study of the clinical, bacteriologic, and serum antibody titer response of 22 men who received therapy with trimethoprim-sulfamethoxazole for chronic prostatitis due to various strains of Escherichia coli was done."	7.66	Serum antibody titers in treatment with trimethoprim-sulfamethoxazole for chronic prostatitis. ( Meares, EM, 1978)
"Fifteen patients with chronic bacterial prostatitis were treated with trimethoprim-sulfamethoxazole for three months."	7.65	Bacterial prostatitis: treatment with trimethoprim-sulfamethoxazole. ( Lytton, B; McGuire, EJ, 1976)
"Norfloxacin is a lipid-soluble weak organic acid bound to plasma proteins to a low extent."	6.66	Norfloxacin versus co-trimoxazole in the treatment of recurring urinary tract infections in men. ( Cook, T; Hoagland, VL; Sabbaj, J, 1986)
"Review of the treatment of chronic non-bacterial prostatitis, defined by the presence of more than 500 leucocytes per mm3 in the expressed prostatic secretion (EPS), showed symptomatic response after 3 months of minocycline, trimethoprim, co-trimoxazole or diazepam."	3.66	Review of results of four regimens for treatment of chronic non-bacterial prostatitis. ( Simmons, PD; Thin, RN, 1983)
"A comparative study of the clinical, bacteriologic, and serum antibody titer response of 22 men who received therapy with trimethoprim-sulfamethoxazole for chronic prostatitis due to various strains of Escherichia coli was done."	3.66	Serum antibody titers in treatment with trimethoprim-sulfamethoxazole for chronic prostatitis. ( Meares, EM, 1978)
"Fifteen patients with chronic bacterial prostatitis were treated with trimethoprim-sulfamethoxazole for three months."	3.65	Bacterial prostatitis: treatment with trimethoprim-sulfamethoxazole. ( Lytton, B; McGuire, EJ, 1976)
"Norfloxacin is a lipid-soluble weak organic acid bound to plasma proteins to a low extent."	2.66	Norfloxacin versus co-trimoxazole in the treatment of recurring urinary tract infections in men. ( Cook, T; Hoagland, VL; Sabbaj, J, 1986)
"The results of the treatment of chronic bacterial prostatitis are disappointing."	2.36	Chronic bacterial prostatitis: theoretical and experimental considerations. ( Iversen, P; Jensen, KM; Madsen, PO, 1983)
"New developments in treatment of urinary tract infections will be discussed."	2.35	New developments in the diagnosis and treatment of urinary tract infections. ( Kunn, CM, 1975)
"Previous reports of melioidosis in Sabah are reviewed and a detailed account of a case, presenting as prostatitis, in a 40-year-old British male is given."	1.26	Melioidosis presenting as prostatitis--a case report from Sabah. ( Kan, SK; Kay, RW, 1978)

Timeframe	Studies, this research(%)	All Research%
pre-1990	49 (98.00)	18.7374
1990's	1 (2.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
DRAPER, JW	1
AKBARI, A	1
WARD, JN	1
Meares, EM	8
Barbalias, GA	1
Madsen, PO	2
Jensen, KM	1
Iversen, P	1
Milingos, S	1
Creatsas, G	1
Messinis, J	1
Lolis, D	1
Kaskarelis, D	1
Simmons, PD	2
Thin, RN	2
Hofstetter, A	1
Friesen, A	1
Bishop-Freudling, GB	1
Vergin, H	1
Ristuccia, AM	1
Cunha, BA	1
Ronald, AR	1
Milkovich, G	1
Eron, LJ	1
Baumueller, A	1
Pfau, A	2
Perlberg, S	1
Shapira, A	1
Drach, GW	2
Gleckman, R	1
Alvarez, S	1
Joubert, DW	1
Geddes, AM	1
Ball, AP	1
Farrell, ID	1
Young, DV	1
Poretz, DM	1
Paulson, DF	1
White, RD	1
Kan, SK	1
Kay, RW	1
Pechere, JC	1
Ludwig, G	1
Sacks, T	1
Fryjordet, A	1
Ous, S	1
Kunn, CM	1
Dow, D	2
Bissada, NK	1
Redman, JF	1
Schiffman, DO	1
Stamey, TA	1
McGuire, EJ	1
Lytton, B	1
Greenberger, PA	1
Bergman, B	1
Wedrén, H	1
Holm, SE	1
Boerema, JB	1
Kaneko, S	1
Akiyama, T	1
Kurita, T	1
Rageth, JC	1
Da Rugna, D	1
Johannisson, E	1
Sabbaj, J	1
Hoagland, VL	1
Cook, T	1
Reeves, DS	2
Thomas, AL	1
Wise, R	1
Blacklock, NJ	1
Soul, JO	1
Lange, D	1
Schirren, C	1
Chesley, AE	1
Haveland, H	1
Kumar, S	1
Jones, GW	1
Robb, CA	2
Carroll, PT	2
Tippett, LO	2
Langston, JB	2
Ghilchik, M	1

Article	Year
Chronic bacterial prostatitis: theoretical and experimental considerations. Urological research, 1983, Volume: 11, Issue:1 Topics: Animals; Antibody Formation; Antibody-Coated Bacteria Test, Urinary; Bacterial Infections; Chronic D	1983
Prostatitis and related diseases. Disease-a-month : DM, 1980, Volume: 26, Issue:8 Topics: Acute Disease; Animals; Anti-Bacterial Agents; Bacterial Infections; Bacteriological Techniques; Cal	1980
Urinary tract infections: the efficacy of trimethoprim/sulfamethoxazole. Clinical therapeutics, 1980, Volume: 3, Issue:3 Topics: Cystitis; Drug Combinations; Humans; Kidney Diseases; Male; Microbial Sensitivity Tests; Prostatitis	1980
[Modern trends in the diagnosis and therapy of prostatitis]. Recenti progressi in medicina, 1981, Volume: 70, Issue:6 Topics: Bacteria; Drug Therapy, Combination; Gentamicins; Humans; Immunologic Techniques; Male; Prostate; Pr	1981
Prostatitis: diagnosis and treatment. Drugs, 1978, Volume: 15, Issue:6 Topics: Acute Disease; Bacterial Infections; Chronic Disease; Humans; Male; Prostatitis; Sulfamethoxazole; T	1978
Drug therapy reviews: trimethoprim-sulfamethoxazole. American journal of hospital pharmacy, 1979, Volume: 36, Issue:7 Topics: Acute Disease; Bacteria; Child; Chronic Disease; Diagnostic Errors; Drug Administration Schedule; Dr	1979
Co-trimoxazole for the treatment of serious infections. The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:B Topics: Bacterial Infections; Brucellosis; Carrier State; Drug Combinations; Humans; Intestinal Diseases; Ma	1979
New developments in the diagnosis and treatment of urinary tract infections. The Journal of urology, 1975, Volume: 113, Issue:5 Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Carbenicillin; Female; Humans; Hydroxamic	1975

Article	Year
[Chronic prostatitis. A therapeutic problem]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Jan-10, Volume: 95, Issue:1 Topics: Adult; Bacteria; Bacteriological Techniques; Chronic Disease; Clinical Trials as Topic; Drug Combina	1975
Norfloxacin versus co-trimoxazole in the treatment of recurring urinary tract infections in men. Scandinavian journal of infectious diseases. Supplementum, 1986, Volume: 48 Topics: Anti-Infective Agents, Urinary; Bacteria; Drug Combinations; Humans; Male; Microbial Sensitivity Tes	1986
Use of trimethoprim-sulfamethoxazole in chronic prostatitis. Urology, 1973, Volume: 2, Issue:3 Topics: Bacteria; Chronic Disease; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Foll	1973

Article	Year
THERAPEUTIC PROBLEMS IN URINARY INFECTIONS. Southern medical journal, 1964, Volume: 57 Topics: Chloramphenicol; Enterobacter aerogenes; Escherichia coli Infections; Humans; Hydrocortisone; Imidaz	1964
Prostatitis: bacterial, nonbacterial, and prostatodynia. Seminars in urology, 1983, Volume: 1, Issue:2 Topics: Acute Disease; Adult; Bacteriuria; Diagnosis, Differential; Drug Combinations; Enterobacteriaceae In	1983
Treatment of chronic prostatitis by consecutive per os administration of doxycycline, sulfamethoxazole/trimethoprim, and cephalexin. International journal of clinical pharmacology, therapy, and toxicology, 1983, Volume: 21, Issue:6 Topics: Administration, Oral; Adult; Anti-Infective Agents, Urinary; Cephalexin; Chronic Disease; Doxycyclin	1983
A method for recognising non-bacterial prostatitis: preliminary observations. The British journal of venereal diseases, 1983, Volume: 59, Issue:5 Topics: Adult; Bacteria; Cell Aggregation; Chronic Disease; Drug Combinations; Humans; Leukocyte Count; Leuk	1983
Review of results of four regimens for treatment of chronic non-bacterial prostatitis. British journal of urology, 1983, Volume: 55, Issue:5 Topics: Adult; Anti-Infective Agents, Urinary; Chronic Disease; Diazepam; Drug Combinations; Humans; Leukocy	1983
[Co-trimoxazole concentration in the prostatic fluid of patients with subacute and chronic prostatitis]. Fortschritte der Medizin, 1984, Mar-08, Volume: 102, Issue:9 Topics: Administration, Oral; Anti-Infective Agents, Urinary; Biological Availability; Chronic Disease; Drug	1984
Current concepts in antimicrobial therapy of prostatitis. Urology, 1982, Volume: 20, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Cephalosporins; Chlamydia Infections; Drug Co	1982
Unusual occurrence of Shigella prostatitis, successfully treated. Virginia medical, 1980, Volume: 107, Issue:8 Topics: Adult; Drug Combinations; Dysentery, Bacillary; Humans; Male; Prostatitis; Shigella sonnei; Staphylo	1980
Prostatitis. Kidney international, 1981, Volume: 20, Issue:2 Topics: Aged; Ampicillin; Animals; Bacterial Infections; Drug Combinations; Humans; Male; Middle Aged; Prost	1981
Secretion of various antimicrobial substances in dogs with experimental bacterial prostatitis. Urological research, 1977, Volume: 5, Issue:4 Topics: Ampicillin; Animals; Anti-Bacterial Agents; Dogs; Doxycycline; Drug Evaluation, Preclinical; Erythro	1977
The pH of the prostatic fluid in health and disease: implications of treatment in chronic bacterial prostatitis. The Journal of urology, 1978, Volume: 119, Issue:3 Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ch	1978
Long-term therapy of chronic bacterial prostatitis with trimethoprim-sulfamethoxazole. Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No Topics: Acinetobacter Infections; Administration, Oral; Adult; Aged; Bacterial Infections; Body Fluids; Drug	1975
In vitro antibiotic susceptibility of bacteria isolated from prostatic fluid. Urology, 1979, Volume: 14, Issue:3 Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Cephalexin; Drug Combinations; Humans; Male; Minocyclin	1979
Serum antibody titers in treatment with trimethoprim-sulfamethoxazole for chronic prostatitis. Urology, 1978, Volume: 11, Issue:2 Topics: Adult; Antibodies, Bacterial; Chronic Disease; Drug Combinations; Escherichia coli; Escherichia coli	1978
Treatment of Salmonella prostatitis with trimethoprim-sulfamethoxazole. Southern medical journal, 1978, Volume: 71, Issue:6 Topics: Adult; Drug Combinations; Humans; Male; Prostatitis; Salmonella Infections; Sulfamethoxazole; Trimet	1978
Trimethoprium-sulfamethoxazole and minocycline- hydrochloride in the treatment of culture-proved bacterial prostatitis. The Journal of urology, 1978, Volume: 120, Issue:2 Topics: Bacterial Infections; Drug Combinations; Humans; Male; Minocycline; Prostatitis; Recurrence; Sulfame	1978
Melioidosis presenting as prostatitis--a case report from Sabah. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1978, Volume: 72, Issue:5 Topics: Adult; Ampicillin; Drug Combinations; Gentamicins; Humans; Infertility, Male; Male; Melioidosis; Min	1978
Combination chemotherapy of infectious diseases. Chairman's summing-up and conclusions. Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No Topics: Bacterial Infections; Bronchitis; Drug Combinations; Drug Evaluation; Dysentery, Bacillary; Female;	1975
[Epididymitis]. Fortschritte der Medizin, 1977, May-12, Volume: 95, Issue:18 Topics: Adult; Diagnosis, Differential; Drug Combinations; Epididymitis; Gonorrhea; Hernia; Humans; Infant,	1977
Chronic bacterial prostatitis: new therapeutic aspects. British journal of urology, 1976, Volume: 48, Issue:4 Topics: Adult; Bacterial Infections; Drug Combinations; Humans; Kanamycin; Male; Middle Aged; Prostatitis; S	1976
Trimethorpim-sulfamethoxazole in the treatment of chronic prostatitis. Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No Topics: Administration, Oral; Bacterial Infections; Bacteriological Techniques; Bacteriuria; Biopsy, Needle;	1975
Managing infections of the prostate gland. American family physician, 1975, Volume: 11, Issue:2 Topics: Acute Disease; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Chronic Disease; Diagnosis, Di	1975
Evaluation of an anti-infective combination. Trimethoprim-sulfamethoxazole (Bactrim, Septra). JAMA, 1975, Feb-10, Volume: 231, Issue:6 Topics: Acute Disease; Administration, Oral; Adult; Bacteria; Bacterial Infections; Brucellosis; Child; Chro	1975
Letter: Trimethoprim-sulfamethoxazole therapy for prostatitis. JAMA, 1975, Sep-08, Volume: 233, Issue:10 Topics: Animals; Dogs; Humans; Male; Prostatitis; Sulfamethoxazole; Trimethoprim	1975
Bacterial prostatitis: treatment with trimethoprim-sulfamethoxazole. Urology, 1976, Volume: 7, Issue:5 Topics: Bacterial Infections; Drug Combinations; Follow-Up Studies; Humans; Male; Prostatitis; Recurrence; S	1976
Allergy to sulfa drugs with postcoital urticaria. JAMA, 1991, Mar-20, Volume: 265, Issue:11 Topics: Coitus; Drug Hypersensitivity; Female; Humans; Male; Prostatitis; Sulfamethoxazole; Trimethoprim; Ur	1991
Long-term antibiotic treatment of chronic bacterial prostatitis. Effect on bacterial flora. British journal of urology, 1989, Volume: 63, Issue:5 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacterial Infections; Cefadroxil; Drug	1989
New 4-quinolones in the treatment of urinary tract infections. Pharmaceutisch weekblad. Scientific edition, 1986, Feb-21, Volume: 8, Issue:1 Topics: Anti-Infective Agents, Urinary; Ciprofloxacin; Drug Combinations; Humans; Male; Norfloxacin; Pefloxa	1986
[Combined treatment of chronic prostatitis with sulfamethoxazole-trimethoprim and hachimi-ji-oh-gan]. Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Drug Therapy, Combination; Drugs, Chinese Herbal; H	1988
[The effect of prostatitis on the spermiogram]. Helvetica chirurgica acta, 1988, Volume: 55, Issue:3 Topics: Doxycycline; Drug Combinations; Drug Therapy, Combination; Humans; Leukocyte Count; Male; Prostatiti	1988
Lack of homogeneity of bladder urine. Lancet (London, England), 1974, Jun-22, Volume: 1, Issue:7869 Topics: Cephaloridine; Humans; Injections, Intramuscular; Male; Prostatitis; Sulfamethoxazole; Trimethoprim;	1974
Trimethoprim sulfamethoxazole therapy of chronic bacterial prostatitis. The Journal of urology, 1974, Volume: 111, Issue:5 Topics: Adolescent; Adult; Aged; Bacterial Infections; Candidiasis, Oral; Child; Drug Eruptions; Escherichia	1974
[Studies on the influence of trimethoprim/sulfamethoxazole on the quality of sperm in andrologic patients and a contribution to the pharmacological testing of a drug on the spermatogenetic activity of the testis]. Zeitschrift fur Hautkrankheiten, 1974, Oct-15, Volume: 49, Issue:20 Topics: Acne Vulgaris; Eczema; Humans; Male; Prostatitis; Sperm Motility; Spermatogenesis; Spermatozoa; Sulf	1974
Prostatitis. Observations on activity of trimethoprim-sulfamethoxazole in the prostate. The Journal of infectious diseases, 1973, Volume: 128 Topics: Adult; Bacterial Infections; Chronic Disease; Drug Combinations; Escherichia coli Infections; Humans	1973
[Antibiotics in prostatitis. Results of a meeting at the Institute of Pharmacotherapy]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Oct-30, Volume: 92, Issue:30 Topics: Animals; Anti-Infective Agents; Dogs; Folic Acid Antagonists; Humans; Hydrogen-Ion Concentration; Ma	1972
Comparative study of Gantanol in serum and prostatic tissue. Journal of the National Medical Association, 1973, Volume: 65, Issue:1 Topics: Humans; Male; Prostate; Prostatitis; Sulfamethoxazole	1973
The diffusion of selected sulfonamides, trimethoprim, and diaveridine into prostatic fluid of dogs. Investigative urology, 1971, Volume: 8, Issue:6 Topics: Animals; Dogs; Drug Synergism; Escherichia coli; Folic Acid Antagonists; Male; Prostate; Prostatitis	1971
Antibacterial activity of diaveridine, trimethoprim, and selected sulfonamides in prostatic fluid. Investigative urology, 1971, Volume: 8, Issue:6 Topics: Animals; Dogs; Drug Synergism; Enterococcus faecalis; Escherichia; Escherichia coli; Folic Acid Anta	1971
Secretion of the antibacterial substance trimethoprim in the prostatic fluid of dogs. British journal of urology, 1970, Volume: 42, Issue:1 Topics: Animals; Anti-Infective Agents; Dogs; Drug Resistance, Microbial; Drug Synergism; Folic Acid Antagon	1970

sulfamethoxazole and Prostatitis

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