Page last updated: 2024-11-04

sulfamethoxazole and Pneumococcal Infections

sulfamethoxazole has been researched along with Pneumococcal Infections in 21 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Pneumococcal Infections: Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.

Research Excerpts

ExcerptRelevanceReference
"Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection."9.04Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975)
"The combination trimethoprim-sulfamethoxazole was given in high dosage (four tablets twice daily) for either 2 or 5 days to 20 patients with sinusitis diagnosed on clinical grounds."7.65Use of high-dosage trimethoprim-sulfamethoxazole in sinusitis. ( Whitehead, E, 1975)
"Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection."5.04Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975)
"The combination trimethoprim-sulfamethoxazole was given in high dosage (four tablets twice daily) for either 2 or 5 days to 20 patients with sinusitis diagnosed on clinical grounds."3.65Use of high-dosage trimethoprim-sulfamethoxazole in sinusitis. ( Whitehead, E, 1975)
"Pneumococcal diseases are a leading cause of morbidity and mortality among children globally, and the burden of these diseases might be worsened by antimicrobial resistance."2.72Antimicrobial resistance in paediatric ( Andrejko, K; Hausdorff, WP; Laxminarayan, R; Lewnard, JA; Ratnasiri, B, 2021)
"Patients with multiple myeloma are at risk for bacterial infections such as Streptococcus pneumoniae, Haemophilus influenzae, and Escherichia coli."2.44[Compromised immune function in multiple myeloma]. ( Yoshida, M, 2007)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199013 (61.90)18.7374
1990's3 (14.29)18.2507
2000's2 (9.52)29.6817
2010's2 (9.52)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Andrejko, K1
Ratnasiri, B1
Hausdorff, WP1
Laxminarayan, R1
Lewnard, JA1
Dayie, NT1
Arhin, RE1
Newman, MJ1
Dalsgaard, A1
Bisgaard, M1
Frimodt-Møller, N1
Slotved, HC1
Chi, H1
Chiu, NC1
Huang, FY1
Hsu, CH1
Lee, KS1
Huang, LM1
Hsieh, YC1
Blossom, DB1
Namayanja-Kaye, G1
Nankya-Mutyoba, J1
Mukasa, JB1
Bakka, H1
Rwambuya, S1
Windau, A1
Bajaksouzian, S1
Walker, CJ1
Joloba, ML1
Kityo, C1
Mugyenyi, P1
Whalen, CC1
Jacobs, MR1
Salata, RA1
Yoshida, M1
Linares, J2
Pérez, JL2
Garau, J2
Martin, R2
Kalin, M1
Carlsson, B1
Karlsson, I1
Murgui, L1
Markman, M1
Mannisi, J1
Dick, JD1
Filburn, B1
Santos, GW1
Saral, R1
Jossart, GH2
Canafax, DM2
Erdmann, GR2
Lovdahl, MJ1
Russlie, HQ1
Juhn, SK2
Giebink, GS2
Haglund, LA1
Istre, GR1
Pickett, DA1
Welch, DF1
Fine, DP1
Joly, J1
Ninane, G1
Kraytman, M1
Cameron, GG1
Pomahac, AC1
Johnston, MT1
Whitehead, E1
Levitt, DG1
Kucera, P1
Le, CT1
Henderson, FW1
Gilligan, PH1
Wait, K1
Goff, DA1
Keren, G1
Barzilai, A1
Rubinstein, E1
Plotkin, SA1
Geddes, AM1
Böhni, E2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Study on Pathogenic Surveillance and Nasopharyngeal Carriage of Children and Adolescents Based on Hospitals and Communities in Hainan Province[NCT05912010]6,000 participants (Anticipated)Observational2023-04-24Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for sulfamethoxazole and Pneumococcal Infections

ArticleYear
Antimicrobial resistance in paediatric
    The Lancet. Microbe, 2021, Volume: 2, Issue:9

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Child; Drug Resistance, Bacterial; Hum

2021
[Compromised immune function in multiple myeloma].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:12

    Topics: Antibiotic Prophylaxis; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Multiple Myelo

2007
Chemotherapy.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Aminoglycosides; Ampicillin; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Antivi

1974

Trials

2 trials available for sulfamethoxazole and Pneumococcal Infections

ArticleYear
A double-blind comparative study of ampicillin, co-trimoxazole and josamycin in anthraco-silicotic miners, assessed by transtracheal puncture.
    The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:5

    Topics: Ampicillin; Anthracosilicosis; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Clinical Tri

1977
Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Administration, Oral; Ampicillin; Bacterial Infections; Body Weight; Child; Clinical Trials as Topic

1975

Other Studies

16 other studies available for sulfamethoxazole and Pneumococcal Infections

ArticleYear
Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children.
    Microbial drug resistance (Larchmont, N.Y.), 2015, Volume: 21, Issue:6

    Topics: Anti-Bacterial Agents; Asymptomatic Diseases; Cefotaxime; Child; Child, Preschool; Disk Diffusion An

2015
Acute otitis media caused by Streptococcus pneumoniae serotype 19A ST320 clone: epidemiological and clinical characteristics.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Child; Child, Preschool; Drug Resistance, Bac

2018
Oropharyngeal colonization by Streptococcus pneumoniae among HIV-infected adults in Uganda: assessing prevalence and antimicrobial susceptibility.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2006, Volume: 10, Issue:6

    Topics: Adult; Ambulatory Care Facilities; Anti-Infective Agents; Carrier State; Cross-Sectional Studies; Dr

2006
Cotrimoxazole resistance in pneumococci.
    European journal of clinical microbiology, 1983, Volume: 2, Issue:5

    Topics: Adult; Child; Drug Combinations; Drug Resistance, Microbial; Humans; Penicillin Resistance; Pneumoco

1983
Frequency and type distribution of pneumococcal strains in the Stockholm region with resistance or reduced susceptibility to antibiotics.
    Scandinavian journal of infectious diseases, 1984, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Chloramphen

1984
Comparative susceptibilities of penicillin-resistant pneumococci to co-trimoxazole, vancomycin, rifampicin and fourteen beta-lactam antibiotics.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 13, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; beta-Lactams; Carrier State; Child; Dr

1984
Sulfamethoxazole-trimethoprim-resistant pneumococcal sepsis.
    JAMA, 1982, Dec-10, Volume: 248, Issue:22

    Topics: Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Drug Resistance, Microbial; Female; Graft

1982
Effect of Streptococcus pneumoniae and influenza A virus on middle ear antimicrobial pharmacokinetics in experimental otitis media.
    Pharmaceutical research, 1994, Volume: 11, Issue:6

    Topics: Amoxicillin; Animals; Anti-Infective Agents; Chinchilla; Half-Life; Influenza A virus; Mucous Membra

1994
Invasive pneumococcal disease in central Oklahoma: emergence of high-level penicillin resistance and multiple antibiotic resistance. Pneumococcus Study Group.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:6

    Topics: Adolescent; Adult; Aged; Drug Resistance, Microbial; Erythromycin; Humans; Microbial Sensitivity Tes

1993
Use of high-dosage trimethoprim-sulfamethoxazole in sinusitis.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Adolescent; Bacteria; Bacterial Infections; Drug Combinations; Drug Evaluation; Haemophilus Infectio

1975
An experimental model for measuring middle ear antimicrobial drug penetration in otitis media.
    Pharmaceutical research, 1990, Volume: 7, Issue:12

    Topics: Amoxicillin; Animals; Chinchilla; Ear, Middle; Otitis Media, Suppurative; Pneumococcal Infections; S

1990
Nasopharyngeal carriage of antibiotic-resistant pneumococci by children in group day care.
    The Journal of infectious diseases, 1988, Volume: 157, Issue:2

    Topics: Amoxicillin; Carrier State; Cefuroxime; Child Day Care Centers; Child, Preschool; Drug Combinations;

1988
Sepsis caused by sulfamethoxazole-trimethoprim-resistant pneumococci.
    Israel journal of medical sciences, 1987, Volume: 23, Issue:7

    Topics: Drug Combinations; Drug Resistance, Microbial; Female; Humans; Infant; Pneumococcal Infections; Stre

1987
Antibiotics--1968. Review.
    Clinical pediatrics, 1968, Volume: 7, Issue:10

    Topics: Ampicillin; Anti-Bacterial Agents; Cephalosporins; Child; Cloxacillin; Colistin; Drug Synergism; Dys

1968
Chemotherapeutic activity of the combination of trimethoprim and sulphamethoxazole in infections of mice.
    Postgraduate medical journal, 1969, Volume: 45

    Topics: Animals; Drug Synergism; Escherichia coli Infections; Folic Acid Antagonists; Haemophilus Infections

1969
[Comparative bacteriological investigations with the combination trimethoprim/sulfamethoxazole in vitro and in vivo].
    Chemotherapy, 1969, Volume: 14

    Topics: Agar; Animals; Anti-Bacterial Agents; Culture Media; Drug Resistance, Microbial; Drug Synergism; Ent

1969