Page last updated: 2024-11-04

sulfamethoxazole and Pancytopenia

sulfamethoxazole has been researched along with Pancytopenia in 13 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.

Research Excerpts

ExcerptRelevanceReference
"The authors report a case of fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy in a patient with folic acid deficiency."7.66[Fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy (author's transl)]. ( Bald, P; Barale, F; Boillot, A; Daoudal, P; Rozenbaum, A; Stimmesse, B, 1979)
"In 8 of 18 homosexual men with the acquired immunodeficiency syndrome (AIDS) and Pneumocystis carinii pneumonia (PCP) treated with intravenous co-trimoxazole (trimethoprim-sulphamethoxazole) apparent drug-related complications developed during the course of acute therapy."3.66Complications of co-trimoxazole in treatment of AIDS-associated Pneumocystis carinii pneumonia in homosexual men. ( Abrams, DI; Ammann, AJ; Golden, JA; Jaffe, HS; Lewis, BJ, 1983)
"The authors report a case of fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy in a patient with folic acid deficiency."3.66[Fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy (author's transl)]. ( Bald, P; Barale, F; Boillot, A; Daoudal, P; Rozenbaum, A; Stimmesse, B, 1979)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199012 (92.31)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartha, P1
Bron, R1
Levy, Y1
Jaffe, HS1
Abrams, DI1
Ammann, AJ1
Lewis, BJ1
Golden, JA1
Le Blanc, C1
Bricard, H1
Levrot, A1
Leroy, G1
Trovero, C1
Quesnel, J1
Chanu, B1
Kernbaum, S1
Uzzan, B1
Faille, A1
Blasetti, A1
Rouffy, J1
Stimmesse, B1
Daoudal, P1
Boillot, A1
Bald, P1
Rozenbaum, A1
Barale, F1
Blackwell, EA1
Hawson, GA1
Leer, J1
Bain, B1
Casthelat, J1
Jaouen, E1
Deroide, JP1
Jeurissen, ME1
Boerbooms, AM1
van de Putte, LB1
Thevenet, JP1
Ristori, JM1
Cure, H1
Mizony, MH1
Bussiere, JL1
Maricic, M1
Davis, M1
Gall, EP1
Thomas, DR1
Dover, JS1
Camp, RD1
Uppenkamp, M1
Hoensch, H1
König, E1
Przybilla, CG1
Ohnhaus, EE1
Gordon-Smith, EC1

Other Studies

13 other studies available for sulfamethoxazole and Pancytopenia

ArticleYear
[Fatal pancytopenia and methotrexate-trimethoprim-sulfamethoxazole interaction].
    Harefuah, 2004, Volume: 143, Issue:6

    Topics: Aged; Diagnosis, Differential; Drug Interactions; Fatal Outcome; Female; Humans; Methotrexate; Pancy

2004
Complications of co-trimoxazole in treatment of AIDS-associated Pneumocystis carinii pneumonia in homosexual men.
    Lancet (London, England), 1983, Nov-12, Volume: 2, Issue:8359

    Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Fever; Headache; Homosexuality; Humans

1983
[Pancytopenia associated with sulfamethoxazole-trimethoprime I.V. therapy (author's transl)].
    Anesthesie, analgesie, reanimation, 1981, Volume: 38, Issue:5-6

    Topics: Aged; Drug Combinations; Humans; Injections, Intravenous; Male; Pancytopenia; Sulfamethoxazole; Trim

1981
[Bone marrow aplasia induced by sulfamethoxazole-trimethoprim. Evidence of an allergic mechanism].
    La Nouvelle presse medicale, 1981, Nov-21, Volume: 10, Issue:42

    Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Pancytopenia; Sulfamethoxazole; Trimethoprim

1981
[Fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy (author's transl)].
    Anesthesie, analgesie, reanimation, 1979, Volume: 36, Issue:11-12

    Topics: Drug Combinations; Folic Acid Deficiency; Humans; Male; Middle Aged; Pancytopenia; Sulfamethoxazole;

1979
Acute pancytopenia due to megaloblastic arrest in association with co-trimoxazole.
    The Medical journal of Australia, 1978, Jul-01, Volume: 2, Issue:1

    Topics: Acute Disease; Aged; Anemia, Megaloblastic; Bone Marrow Diseases; Drug Combinations; Erythrocytes, A

1978
[Pancytopenia resulting from treatment with sulfamethoxazole-trimethoprim].
    La Nouvelle presse medicale, 1978, Oct-14, Volume: 7, Issue:35

    Topics: Aged; Drug Combinations; Female; Humans; Pancytopenia; Sulfamethoxazole; Trimethoprim

1978
Pancytopenia and methotrexate with trimethoprim-sulfamethoxazole.
    Annals of internal medicine, 1989, Aug-01, Volume: 111, Issue:3

    Topics: Aged; Aged, 80 and over; Drug Combinations; Drug Interactions; Female; Humans; Methotrexate; Pancyto

1989
[Pancytopenia during treatment of rheumatoid arthritis with methotrexate after administration of trimethoprim-sulfamethoxazole].
    Presse medicale (Paris, France : 1983), 1987, Sep-19, Volume: 16, Issue:30

    Topics: Anti-Infective Agents; Arthritis, Rheumatoid; Drug Combinations; Drug Synergism; Drug Therapy, Combi

1987
Megaloblastic pancytopenia in a patient receiving concurrent methotrexate and trimethoprim-sulfamethoxazole treatment.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:1

    Topics: Abscess; Breast Diseases; Cough; Drug Combinations; Erythrocytes; Erythrocytes, Abnormal; Female; Fo

1986
Pancytopenia induced by the interaction between methotrexate and trimethoprim-sulfamethoxazole.
    Journal of the American Academy of Dermatology, 1987, Volume: 17, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Drug Combinations; Drug Therapy, Combination; Female

1987
[Pancytopenia and Salmonella infantis infection].
    Der Internist, 1986, Volume: 27, Issue:2

    Topics: Anti-Infective Agents; Drug Combinations; Female; Gastroenteritis; Humans; Middle Aged; Pancytopenia

1986
Treatment of aplastic anemias.
    Hospital practice (Office ed.), 1985, May-15, Volume: 20, Issue:5

    Topics: Adult; Anemia, Aplastic; Anti-Bacterial Agents; Antifungal Agents; Antilymphocyte Serum; Bone Marrow

1985