Page last updated: 2024-11-04

sulfamethoxazole and Middle Ear Inflammation

sulfamethoxazole has been researched along with Middle Ear Inflammation in 64 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Although amoxicillin has long been the preferred drug for treatment of acute otitis media, resistant strains of two relatively common causal organisms have emerged, prompting a search for other antibiotics."9.06Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media. ( Dulberg, C; Feldman, W; Momy, J, 1988)
"We performed a randomized controlled trial of cefaclor administered twice daily compared with trimethoprim-sulfamethoxazole (TMP-SMZ) administered twice daily for the treatment of acute otitis media."9.05A randomized controlled trial of cefaclor compared with trimethoprim-sulfamethoxazole for treatment of acute otitis media. ( Feinstein, JC; Johnson, CE; Knapp, LJ; Marchant, CD; Shurin, PA; Turcyzk, VA; Tutihasi, MA; Wasikowski, DE, 1984)
"We treated 132 children with acute otitis media in a randomized trial comparing trimethoprim-sulfamethoxazole and ampicillin."9.05Trimethoprim-sulfamethoxazole compared with ampicillin in the treatment of acute otitis media. ( Donner, A; Finkelstein, J; Klein, JO; Pelton, SI; Shurin, PA, 1980)
"The tolerabilities of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole (TMP-SMX) suspensions were evaluated in 263 children with otitis media."9.05Comparative tolerability of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole suspensions in children with otitis media. ( Feder, HM, 1982)
"This study was undertaken during the late fall, winter, and early spring months to determine the efficacy of daily trimethoprim/sulfamethoxazole (TMP/SMX) administration in the prevention of recurrent acute otitis media (RAOM) in a specific high-risk pediatric population."9.05Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole. ( Gaskins, JD; Holt, RJ; Kyong, CU; Ward, J; Weart, CW, 1982)
"We report the hematologic changes in 90 black children who were randomized to receive a 10-day course of either trimethoprim-sulfamethoxazole (TMP-SMZ) or amoxicillin as therapy for acute otitis media."9.05Similar hematologic changes in children receiving trimethoprim-sulfamethoxazole or amoxicillin for otitis media. ( Doolittle, M; Feldman, S; Hughes, WT; Lott, L; Roberson, P, 1985)
"Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection."9.04Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975)
"The incidence of hematologic abnormalities was evaluated in 120 children with otitis media treated respectively with cotrimoxazole (trimethoprim-sulfamethoxazole) (group 1), cotrimoxazole plus folinic acid (group 2) and amoxicillin (group 3) in therapeutic doses for ten days."7.67Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole). ( Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N, 1984)
"Two patients had severe thrombocytopenia while taking trimethoprim-sulfamethoxazole."7.66Thrombocytopenia secondary to trimethoprim-sulfamethoxazole. ( Hagen, MD; White, RD, 1983)
"Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media."7.66Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982)
"Strains of Haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media."7.65Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae. ( Klein, JO; Pelton, SI; Scheifele, D; Shurin, PA, 1976)
"Although amoxicillin has long been the preferred drug for treatment of acute otitis media, resistant strains of two relatively common causal organisms have emerged, prompting a search for other antibiotics."5.06Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media. ( Dulberg, C; Feldman, W; Momy, J, 1988)
"We performed a randomized controlled trial of cefaclor administered twice daily compared with trimethoprim-sulfamethoxazole (TMP-SMZ) administered twice daily for the treatment of acute otitis media."5.05A randomized controlled trial of cefaclor compared with trimethoprim-sulfamethoxazole for treatment of acute otitis media. ( Feinstein, JC; Johnson, CE; Knapp, LJ; Marchant, CD; Shurin, PA; Turcyzk, VA; Tutihasi, MA; Wasikowski, DE, 1984)
"We treated 132 children with acute otitis media in a randomized trial comparing trimethoprim-sulfamethoxazole and ampicillin."5.05Trimethoprim-sulfamethoxazole compared with ampicillin in the treatment of acute otitis media. ( Donner, A; Finkelstein, J; Klein, JO; Pelton, SI; Shurin, PA, 1980)
"The tolerabilities of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole (TMP-SMX) suspensions were evaluated in 263 children with otitis media."5.05Comparative tolerability of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole suspensions in children with otitis media. ( Feder, HM, 1982)
"This study was undertaken during the late fall, winter, and early spring months to determine the efficacy of daily trimethoprim/sulfamethoxazole (TMP/SMX) administration in the prevention of recurrent acute otitis media (RAOM) in a specific high-risk pediatric population."5.05Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole. ( Gaskins, JD; Holt, RJ; Kyong, CU; Ward, J; Weart, CW, 1982)
"We report the hematologic changes in 90 black children who were randomized to receive a 10-day course of either trimethoprim-sulfamethoxazole (TMP-SMZ) or amoxicillin as therapy for acute otitis media."5.05Similar hematologic changes in children receiving trimethoprim-sulfamethoxazole or amoxicillin for otitis media. ( Doolittle, M; Feldman, S; Hughes, WT; Lott, L; Roberson, P, 1985)
"Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection."5.04Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975)
"The incidence of hematologic abnormalities was evaluated in 120 children with otitis media treated respectively with cotrimoxazole (trimethoprim-sulfamethoxazole) (group 1), cotrimoxazole plus folinic acid (group 2) and amoxicillin (group 3) in therapeutic doses for ten days."3.67Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole). ( Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N, 1984)
"Two patients had severe thrombocytopenia while taking trimethoprim-sulfamethoxazole."3.66Thrombocytopenia secondary to trimethoprim-sulfamethoxazole. ( Hagen, MD; White, RD, 1983)
"Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media."3.66Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982)
"Strains of Haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media."3.65Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae. ( Klein, JO; Pelton, SI; Scheifele, D; Shurin, PA, 1976)
"Otitis media with effusion is the most common cause of hearing loss in children."2.65Antimicrobial therapy of chronic otitis media with effusion. ( Healy, GB, 1984)
"Antibiotic treatment of acute otitis media (AOM) accounts for a significant number of all antibiotic prescriptions each year."2.37Dilemmas in primary care: antibiotic treatment of acute otitis media. ( Helling, DK; True, BL, 1986)
"Trimethoprim K values were also not affected by model testing sequence (p = 0/760), but were by model type (p = 0."1.29Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics. ( Canafax, DM; Erdmann, GR; Giebink, GS; Le, CT; Lovdahl, MJ; Russlie, H, 1994)
"Antimicrobial treatment of otitis media, especially drug dosing considerations, is largely empiric, with few reported pharmacologic studies of drug distribution into the middle ear."1.28Experimental animal models for studying antimicrobial pharmacokinetics in otitis media. ( Canafax, DM; Erdmann, GR; Giebink, GS; Juhn, SK; Le, CT; Nonomura, N, 1989)
" The small sample volumes were dictated by the chinchilla model of otitis media and our need to collect multiple samples over a 12-h drug dosing interval."1.27High-performance liquid chromatographic analysis of trimethoprim and sulfamethoxazole in microliter volumes of chinchilla middle ear effusion and serum. ( Canafax, DM; Erdmann, GR; Giebink, GS, 1988)
"Acute otitis media is commonly caused by pneumococcus and Hemophilus influenzae."1.27Developments in diagnosing and treating otitis media. ( Eichenwald, H, 1985)
"Thrombocytopenia was noted between the seventh and 16th day (mean, 10."1.26Hematologic abnormalities after oral trimethoprim-sulfamethoxazole therapy in children. ( Asmar, BI; Dajani, AS; Maqbool, S, 1981)

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-199057 (89.06)18.7374
1990's5 (7.81)18.2507
2000's0 (0.00)29.6817
2010's1 (1.56)24.3611
2020's1 (1.56)2.80

Authors

AuthorsStudies
Taha, A1
Adeline, F1
Taha, MK1
Deghmane, AE1
Chi, H1
Chiu, NC1
Huang, FY1
Hsu, CH1
Lee, KS1
Huang, LM1
Hsieh, YC1
PATTON, JM1
ALBAN, J1
REICHELDERFER, TE1
Bläker, F1
Principi, N1
Marchisio, P1
Biasini, A1
Dalla Villa, A1
Biasini, G1
Marks, NJ2
Mills, RP2
Shaheen, OH2
Marchant, CD1
Shurin, PA4
Turcyzk, VA1
Feinstein, JC1
Johnson, CE1
Wasikowski, DE1
Knapp, LJ1
Tutihasi, MA1
Healy, GB1
Clemente, M1
Morera, C1
Hagen, MD1
White, RD1
Pelton, SI2
Donner, A1
Finkelstein, J1
Klein, JO3
Rubin, RH1
Swartz, MN1
Thornsberry, C1
McDougal, LK1
Feder, HM1
Schwartz, RH1
Puglise, J1
Rodriguez, WJ2
Feldman, W2
Richardson, H1
Rennie, B1
Dawson, P1
Gaskins, JD1
Holt, RJ1
Kyong, CU1
Weart, CW1
Ward, J1
Guess, HA1
Cohen, MS1
Klimek, JJ2
Bates, TR1
Nightingale, C1
Lehmann, WB2
Ziemniak, JA1
Quintiliani, R2
Krause, PJ1
Owens, NJ1
Nightingale, CH1
Asmar, BI1
Maqbool, S1
Dajani, AS1
Jossart, GH1
Canafax, DM4
Erdmann, GR4
Lovdahl, MJ2
Russlie, HQ1
Juhn, SK2
Giebink, GS4
Russlie, H1
Le, CT2
Barlan, IB1
Geha, RS1
Schneider, LC1
Cooper, J1
Inman, JS1
Dawson, AF1
Stewart, IA1
Schwartz, R1
Ross, S1
Khan, WN1
Gleckman, R1
Alvarez, S1
Joubert, DW1
Wormser, GP1
Keusch, GT1
Gutman, LT1
Wilfert, CM1
Katz, SL1
Eichenwald, HF1
McCracken, GH1
Steele, TW1
Rich, GE1
Pechere, JC1
Quick, CA2
Goodey, RJ1
Bowers, M1
Scheifele, D1
Cameron, GG1
Pomahac, AC1
Johnston, MT1
Solar Boga, A1
Fontaiña Martinez, M1
Bello Fernandez, A1
Arteche Guisasola, JL1
Rodriguez Valcarcel, G1
Fauskin, G1
Stoddard, J1
DeAngelis, C1
Nonomura, N1
Coffey, JD1
Killelea, DE1
Momy, J1
Dulberg, C1
Kaleida, PH1
Pestalozza, G1
Romagnoli, M1
Tessitore, E1
Formica, U1
Van Hare, GF1
Fauskin, GN1
True, BL1
Helling, DK1
Eichenwald, H1
Moorhouse, EC1
Hickey, MP1
O'Hanrahan, MT1
Clarke, PC1
Feldman, S1
Doolittle, M1
Lott, L1
Roberson, P1
Hughes, WT1
Wallace, RB1
Marsh, BT1
Talbot, DJ1
Wagner, D1
Salzberg, R1
Lewin, EB1
Finland, M1
Zalewski, T1
Gutkowska, J1
Zmudzka, B1
Radzikowski, A1
McGuinness, BW1
Keuth, U1
Sabbagh, M1
Thesen, E1

Reviews

3 reviews available for sulfamethoxazole and Middle Ear Inflammation

ArticleYear
Drug therapy reviews: trimethoprim-sulfamethoxazole.
    American journal of hospital pharmacy, 1979, Volume: 36, Issue:7

    Topics: Acute Disease; Bacteria; Child; Chronic Disease; Diagnostic Errors; Drug Administration Schedule; Dr

1979
Trimethoprim-sulfamethoxazole in the United States.
    Annals of internal medicine, 1979, Volume: 91, Issue:3

    Topics: Adult; Bacterial Infections; Child; Drug Combinations; Drug Synergism; Dysentery, Bacillary; Humans;

1979
Dilemmas in primary care: antibiotic treatment of acute otitis media.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:9

    Topics: Acute Disease; Anti-Bacterial Agents; Drug Combinations; Humans; Otitis Media; Sulfamethoxazole; Tri

1986

Trials

20 trials available for sulfamethoxazole and Middle Ear Inflammation

ArticleYear
Cotrimoxazole in the treatment of serous otitis. A follow-up report.
    The Journal of laryngology and otology, 1983, Volume: 97, Issue:3

    Topics: Child; Chlorpheniramine; Clinical Trials as Topic; Drug Combinations; Follow-Up Studies; Humans; Mul

1983
A randomized controlled trial of cefaclor compared with trimethoprim-sulfamethoxazole for treatment of acute otitis media.
    The Journal of pediatrics, 1984, Volume: 105, Issue:4

    Topics: Acute Disease; Cefaclor; Cephalexin; Child, Preschool; Clinical Trials as Topic; Drug Combinations;

1984
Antimicrobial therapy of chronic otitis media with effusion.
    International journal of pediatric otorhinolaryngology, 1984, Volume: 8, Issue:1

    Topics: Anti-Bacterial Agents; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Ear Canal; Ear

1984
Trimethoprim-sulfamethoxazole compared with ampicillin in the treatment of acute otitis media.
    The Journal of pediatrics, 1980, Volume: 96, Issue:6

    Topics: Acute Disease; Ampicillin; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Exudates and

1980
Comparative tolerability of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole suspensions in children with otitis media.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:3

    Topics: Amoxicillin; Ampicillin; Child; Child, Preschool; Drug Combinations; Humans; Infant; Otitis Media; S

1982
A controlled trial of cotrimoxazole therapy in serous otitis media.
    The Journal of laryngology and otology, 1981, Volume: 95, Issue:10

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; H

1981
Sulphamethoxazole prophylaxis in the otitis-prone child.
    Archives of disease in childhood, 1982, Volume: 57, Issue:8

    Topics: Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Otiti

1982
A trial comparing cefaclor with co-trimoxazole in the treatment of acute otitis media.
    Archives of disease in childhood, 1982, Volume: 57, Issue:8

    Topics: Cefaclor; Cephalexin; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug C

1982
Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole.
    Drug intelligence & clinical pharmacy, 1982, Volume: 16, Issue:5

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Male; O

1982
A comparison between co-trimoxazole and amoxycillin in the treatment of acute otitis media in general practice.
    The Practitioner, 1976, Volume: 217, Issue:1301

    Topics: Adolescent; Adult; Amoxicillin; Ampicillin; Child; Child, Preschool; Clinical Trials as Topic; Deafn

1976
Comparison of penicillin and trimethoprim-sulfamethoxazole in the treatment of ear, nose and throat infections.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Adolescent; Bacteria; Bacterial Infections; Clinical Trials as Topic; Drug Combinations; Drug Evalua

1975
Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Administration, Oral; Ampicillin; Bacterial Infections; Body Weight; Child; Clinical Trials as Topic

1975
Acute otitis media in early infancy. Recurrence and prophylaxis.
    Acta paediatrica Scandinavica, 1991, Volume: 80, Issue:4

    Topics: Acute Disease; Age Factors; Amoxicillin; Ampicillin; California; Drug Combinations; Erythromycin Eth

1991
Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1988, Nov-15, Volume: 139, Issue:10

    Topics: Acute Disease; Adolescent; Amoxicillin; Child; Child, Preschool; Clinical Trials as Topic; Double-Bl

1988
General practice studies with combined pivampicillin/pivmecillinam (Miraxid).
    Irish medical journal, 1985, Volume: 78, Issue:11

    Topics: Adolescent; Adult; Aged; Amdinocillin; Amdinocillin Pivoxil; Amoxicillin; Ampicillin; Drug Combinati

1985
Similar hematologic changes in children receiving trimethoprim-sulfamethoxazole or amoxicillin for otitis media.
    The Journal of pediatrics, 1985, Volume: 106, Issue:6

    Topics: Amoxicillin; Clinical Trials as Topic; Drug Combinations; Female; Humans; Infant; Leukocyte Count; L

1985
A multi-centre general practice clinical evaluation of pivmecillinam plus pivampicillin ('Miraxid') and co-trimoxazole ('Septrin') in respiratory tract infections.
    Current medical research and opinion, 1985, Volume: 9, Issue:10

    Topics: Adolescent; Adult; Aged; Amdinocillin; Amdinocillin Pivoxil; Ampicillin; Anti-Infective Agents; Bron

1985
Trimethoprim-sulfamethoxazole in the treatment of infections of the ears, nose, and throat.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Acute Disease; Bacterial Infections; Chronic Disease; Clinical Trials as Topic; Haemophilus Infectio

1973
[Comparative clinical and bacteriological studies with Bactrim and ampicillin in the pediatrics].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1972, Aug-15, Volume: 61, Issue:33

    Topics: Ampicillin; Anti-Infective Agents; Bacterial Infections; Bronchitis; Child, Preschool; Clinical Tria

1972
Trimethoprim-sulfamethoxazole in the treatment of bacterial infections: report of clinical trials in Japan.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Acute Disease; Bacterial Infections; Child; Clinical Trials as Topic; Drug Combinations; Drug Resist

1973

Other Studies

41 other studies available for sulfamethoxazole and Middle Ear Inflammation

ArticleYear
Haemophilus influenzae drug resistance in France from 2017 to 2021: consideration for treatment of otitis media.
    Journal of global antimicrobial resistance, 2022, Volume: 31

    Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Drug Resistance,

2022
Acute otitis media caused by Streptococcus pneumoniae serotype 19A ST320 clone: epidemiological and clinical characteristics.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Child; Child, Preschool; Drug Resistance, Bac

2018
USE OF SULFAMETHOXAZOLE IN PEDIATRIC INFECTIONS.
    Western medicine; the medical journal of the west, 1964, Volume: 5

    Topics: Bronchitis; Child; Humans; Infant; Infant, Newborn; Laryngitis; Lymphadenitis; Otitis Media; Pediatr

1964
TREATMENT OF B-HEMOLYTIC STREPTOCCAL INFECTION. A STUDY OF THE PEDIATRIC USE OF SULFAMETHOXAZOLE.
    American journal of diseases of children (1960), 1965, Volume: 109

    Topics: Adolescent; Child; Drug Therapy; Humans; Infant; Kidney Diseases; Otitis Media; Pediatrics; Respirat

1965
CLINICAL STUDIES AND THERAPEUTIC USE OF SULFAMETHOXAZOLE IN A PEDIATRIC OUT-PATIENT CLINIC.
    Clinical medicine (Northfield, Ill.), 1964, Volume: 71

    Topics: Asthma; Bronchitis; Child; Drug Therapy; Humans; Otitis Media; Outpatients; Pharyngitis; Respiratory

1964
[Antimicrobial therapy using cotrimoxazole].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1981, Volume: 129, Issue:6

    Topics: Anti-Infective Agents, Urinary; Bacterial Infections; Drug Combinations; Dysentery, Bacillary; Human

1981
Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole).
    Acta paediatrica Scandinavica, 1984, Volume: 73, Issue:6

    Topics: Agranulocytosis; Amoxicillin; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination;

1984
[Open trial using soltrim in otitis media].
    Revista clinica espanola, 1983, Mar-31, Volume: 168, Issue:6

    Topics: Adolescent; Adult; Drug Combinations; Drug Evaluation; Female; Humans; Male; Middle Aged; Otitis Med

1983
Thrombocytopenia secondary to trimethoprim-sulfamethoxazole.
    Southern medical journal, 1983, Volume: 76, Issue:4

    Topics: Acute Disease; Child, Preschool; Drug Therapy, Combination; Female; Folic Acid; Humans; Male; Middle

1983
Trimethoprim-sulfamethoxazole.
    The New England journal of medicine, 1980, Aug-21, Volume: 303, Issue:8

    Topics: Administration, Oral; Adult; Bacteria; Child; Drug Combinations; Drug Interactions; Drug Resistance,

1980
Ampicillin-resistant Haemophilus influenzae. 2. Therapeutic considerations.
    Postgraduate medicine, 1982, Volume: 71, Issue:1

    Topics: Adult; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Child; Chloramphenicol; Drug Combinations; Ha

1982
Drug treatment of otitis media and urinary tract infections.
    American journal of diseases of children (1960), 1982, Volume: 136, Issue:11

    Topics: Agranulocytosis; Child; Humans; Neutropenia; Otitis Media; Sulfamethoxazole; Thrombocytopenia; Trime

1982
Penetration characteristics of trimethoprim-sulfamethoxazole in middle ear fluid of patients with chronic serous otitis media.
    The Journal of pediatrics, 1980, Volume: 96, Issue:6

    Topics: Child; Chronic Disease; Exudates and Transudates; Humans; Otitis Media; Otitis Media with Effusion;

1980
Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media.
    The Journal of infectious diseases, 1982, Volume: 145, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Drug Therapy, Combination; Ea

1982
Hematologic abnormalities after oral trimethoprim-sulfamethoxazole therapy in children.
    American journal of diseases of children (1960), 1981, Volume: 135, Issue:12

    Topics: Amoxicillin; Anemia; Blood; Child; Child, Preschool; Drug Therapy, Combination; Eosinophilia; Female

1981
Effect of Streptococcus pneumoniae and influenza A virus on middle ear antimicrobial pharmacokinetics in experimental otitis media.
    Pharmaceutical research, 1994, Volume: 11, Issue:6

    Topics: Amoxicillin; Animals; Anti-Infective Agents; Chinchilla; Half-Life; Influenza A virus; Mucous Membra

1994
Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics.
    Pharmaceutical research, 1994, Volume: 11, Issue:6

    Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Chinchilla; Diffusion; Disease Models, Animal; Ear, Mid

1994
Therapy for patients with recurrent infections and low serum IgG3 levels.
    The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:2

    Topics: Antibodies; Asthma; Child, Preschool; Evaluation Studies as Topic; Humans; Immunoglobulin G; Immunog

1993
Antimicrobial treatment of otitis media.
    The New Zealand medical journal, 1979, Sep-12, Volume: 90, Issue:643

    Topics: Child; Drug Resistance, Microbial; Humans; Otitis Media; Streptococcus pneumoniae; Sulfamethoxazole;

1979
Treatment of otitis media with trimethoprim-sulfamethoxazole.
    The Journal of pediatrics, 1979, Volume: 95, Issue:4

    Topics: Ampicillin; Child, Preschool; Drug Combinations; Haemophilus influenzae; Humans; Infant; Otitis Medi

1979
Use of trimethoprim-sulfamethoxazole in otitis media.
    The Journal of pediatrics, 1979, Volume: 95, Issue:2

    Topics: Child, Preschool; Drug Combinations; Humans; Infant; Otitis Media; Sulfamethoxazole; Trimethoprim

1979
Use of trimethoprim-sulfamethoxazole in otitis media. Reply.
    The Journal of pediatrics, 1979, Volume: 95, Issue:2

    Topics: Child, Preschool; Drug Combinations; Humans; Infant; Otitis Media; Sulfamethoxazole; Trimethoprim

1979
The rational use of antibiotics in general practice.
    Australian family physician, 1977, Volume: 6, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Clindamycin; Drug Combinations; Epididy

1977
Trimethoprim-sulfamethoxazole for otitis media.
    The Medical letter on drugs and therapeutics, 1978, Jun-30, Volume: 20, Issue:13

    Topics: Bacterial Infections; Child, Preschool; Drug Combinations; Humans; Infant; Microbial Sensitivity Tes

1978
Combination chemotherapy of infectious diseases. Chairman's summing-up and conclusions.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Bacterial Infections; Bronchitis; Drug Combinations; Drug Evaluation; Dysentery, Bacillary; Female;

1975
Antibiotic treatment of secretory otitis media assessed by impedence audiometry.
    The New Zealand medical journal, 1975, Sep-24, Volume: 82, Issue:548

    Topics: Ampicillin; Anti-Bacterial Agents; Audiometry; Child; Child, Preschool; Compliance; Doxycycline; Dru

1975
Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae.
    The Journal of pediatrics, 1976, Volume: 88, Issue:4 Pt 1

    Topics: Ampicillin; Child, Preschool; Drug Combinations; Female; Haemophilus Infections; Haemophilus influen

1976
[Red-colored urine: a new case].
    Anales espanoles de pediatria, 1991, Volume: 35, Issue:5

    Topics: Child, Preschool; Diagnosis, Differential; Drug Combinations; False Positive Reactions; Female; Hema

1991
Cost analysis of therapy of acute otitis media.
    The Pediatric infectious disease journal, 1989, Volume: 8, Issue:3

    Topics: Acute Disease; Child; Cost-Benefit Analysis; Drug Combinations; Humans; Otitis Media; Sulfamethoxazo

1989
Experimental animal models for studying antimicrobial pharmacokinetics in otitis media.
    Pharmaceutical research, 1989, Volume: 6, Issue:4

    Topics: Amoxicillin; Animals; Anti-Infective Agents; Chinchilla; Disease Models, Animal; Ear, Middle; Eustac

1989
Comments on otitis media.
    The Pediatric infectious disease journal, 1989, Volume: 8, Issue:8

    Topics: Anti-Infective Agents; Cefaclor; Colistin; Drug Combinations; Drug Resistance, Microbial; Humans; In

1989
High-performance liquid chromatographic analysis of trimethoprim and sulfamethoxazole in microliter volumes of chinchilla middle ear effusion and serum.
    Journal of chromatography, 1988, Dec-09, Volume: 433

    Topics: Animals; Chinchilla; Chromatography, High Pressure Liquid; Otitis Media; Spectrophotometry, Ultravio

1988
Erythromycin ethylsuccinate-sulfamethoxazole mixture vs. amoxicillin for acute otitis media.
    The Pediatric infectious disease journal, 1988, Volume: 7, Issue:5

    Topics: Amoxicillin; Child, Preschool; Drug Combinations; Erythromycin; Erythromycin Ethylsuccinate; Humans;

1988
[Diagnostic and therapeutic protocol in otitis media in the 1st year of life].
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 1988, Volume: 8 Suppl 19

    Topics: Acute Disease; Age Factors; Amoxicillin; Drug Combinations; Humans; Infant; Infant, Newborn; Middle

1988
Therapy of acute otitis media caused by Branhamella catarrhalis. Preliminary report.
    Drugs, 1986, Volume: 31 Suppl 3

    Topics: Amoxicillin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Neisseriaceae; Otitis Med

1986
Treatment of acute otitis media.
    The Pediatric infectious disease journal, 1987, Volume: 6, Issue:11

    Topics: Amoxicillin; Drug Therapy, Combination; Erythromycin; Erythromycin Ethylsuccinate; Humans; Otitis Me

1987
Developments in diagnosing and treating otitis media.
    American family physician, 1985, Volume: 31, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Vaccines; Child; Child, Preschool; Drug Combinations; Hearing Disor

1985
Trimethoprim-sulfamethoxazole: absorption, excretion, and toxicity in six children.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Agranulocytosis; Bacterial Infections; Carrier State; Child; Dose-Response Relationship, Drug; Drug

1973
[Effect of Septrin on blood tetrahydrofolate concentration in children].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1973, Nov-12, Volume: 28, Issue:46

    Topics: Age Factors; Child; Child, Preschool; Drug Combinations; Humans; Infant; Otitis Media; Sulfamethoxaz

1973
A combination of trimethoprim and sulphamethoxazole in upper respiratory infection.
    Postgraduate medical journal, 1969, Volume: 45

    Topics: Folic Acid Antagonists; Humans; Otitis Media; Pharyngitis; Pyrimidines; Respiratory Tract Infections

1969
[Therapy of bacterial infections in infants and children. Report of 171 cases treated with trimethoprim-sulfamethoxazol].
    Munchener medizinische Wochenschrift (1950), 1970, Apr-24, Volume: 112, Issue:17

    Topics: Anti-Bacterial Agents; Child; Child, Preschool; Drug Synergism; Enterobacteriaceae Infections; Folic

1970