sulfamethoxazole has been researched along with Middle Ear Effusion in 13 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media." | 7.66 | Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982) |
| "Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media." | 3.66 | Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982) |
| "Otitis media with effusion is the most common cause of hearing loss in children." | 2.65 | Antimicrobial therapy of chronic otitis media with effusion. ( Healy, GB, 1984) |
| "Acute otitis media is commonly caused by pneumococcus and Hemophilus influenzae." | 1.27 | Developments in diagnosing and treating otitis media. ( Eichenwald, H, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schreiner, A | 1 |
| Marks, NJ | 2 |
| Mills, RP | 2 |
| Shaheen, OH | 2 |
| Healy, GB | 1 |
| Schwartz, RH | 1 |
| Puglise, J | 1 |
| Rodriguez, WJ | 1 |
| Klimek, JJ | 2 |
| Bates, TR | 1 |
| Nightingale, C | 1 |
| Lehmann, WB | 2 |
| Ziemniak, JA | 1 |
| Quintiliani, R | 2 |
| Krause, PJ | 1 |
| Owens, NJ | 1 |
| Nightingale, CH | 1 |
| Roark, R | 1 |
| Petrofski, J | 1 |
| Berson, E | 1 |
| Berman, S | 2 |
| Barnett, ED | 1 |
| Teele, DW | 1 |
| Klein, JO | 1 |
| Cabral, HJ | 1 |
| Kharasch, SJ | 1 |
| Pestalozza, G | 1 |
| Romagnoli, M | 1 |
| Tessitore, E | 1 |
| Formica, U | 1 |
| Grose, K | 1 |
| Zerbe, GO | 1 |
| Eichenwald, H | 1 |
| Puhakka, H | 1 |
| Haapaniemi, J | 1 |
| Tuohimaa, P | 1 |
| Ruuskanen, O | 1 |
| Eskola, J | 1 |
8 trials available for sulfamethoxazole and Middle Ear Effusion
| Article | Year |
|---|---|
Cotrimoxazole in the treatment of serous otitis. A follow-up report.
Topics: Child; Chlorpheniramine; Clinical Trials as Topic; Drug Combinations; Follow-Up Studies; Humans; Mul | 1983 |
Antimicrobial therapy of chronic otitis media with effusion.
Topics: Anti-Bacterial Agents; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Ear Canal; Ear | 1984 |
A controlled trial of cotrimoxazole therapy in serous otitis media.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; H | 1981 |
Sulphamethoxazole prophylaxis in the otitis-prone child.
Topics: Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Otiti | 1982 |
Practice variations among pediatricians and family physicians in the management of otitis media.
Topics: Child, Preschool; Colorado; Decision Making; Family Practice; Humans; Infant; Male; Middle Ear Venti | 1995 |
Comparison of ceftriaxone and trimethoprim-sulfamethoxazole for acute otitis media. Greater Boston Otitis Media Study Group.
Topics: Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Child, Preschool; Drug Therapy, Combination; Fem | 1997 |
Medical management of chronic middle-ear effusion. Results of a clinical trial of prednisone combined with sulfamethoxazole and trimethoprim.
Topics: Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Combin | 1987 |
Peroral prednisolone in the treatment of middle-ear effusion in children: a double-blind study.
Topics: Administration, Oral; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug C | 1985 |
5 other studies available for sulfamethoxazole and Middle Ear Effusion
| Article | Year |
|---|---|
Pathogenicity of Branhamella catarrhalis.
Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Combinations; Drug Resistance, Microbial; Erythrom | 1984 |
Penetration characteristics of trimethoprim-sulfamethoxazole in middle ear fluid of patients with chronic serous otitis media.
Topics: Child; Chronic Disease; Exudates and Transudates; Humans; Otitis Media; Otitis Media with Effusion; | 1980 |
Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Drug Therapy, Combination; Ea | 1982 |
[Diagnostic and therapeutic protocol in otitis media in the 1st year of life].
Topics: Acute Disease; Age Factors; Amoxicillin; Drug Combinations; Humans; Infant; Infant, Newborn; Middle | 1988 |
Developments in diagnosing and treating otitis media.
Topics: Anti-Bacterial Agents; Bacterial Vaccines; Child; Child, Preschool; Drug Combinations; Hearing Disor | 1985 |