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sulfamethoxazole and Middle Ear Effusion

sulfamethoxazole has been researched along with Middle Ear Effusion in 13 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Research Excerpts

ExcerptRelevanceReference
"Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media."7.66Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982)
"Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media."3.66Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982)
"Otitis media with effusion is the most common cause of hearing loss in children."2.65Antimicrobial therapy of chronic otitis media with effusion. ( Healy, GB, 1984)
"Acute otitis media is commonly caused by pneumococcus and Hemophilus influenzae."1.27Developments in diagnosing and treating otitis media. ( Eichenwald, H, 1985)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's2 (15.38)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schreiner, A1
Marks, NJ2
Mills, RP2
Shaheen, OH2
Healy, GB1
Schwartz, RH1
Puglise, J1
Rodriguez, WJ1
Klimek, JJ2
Bates, TR1
Nightingale, C1
Lehmann, WB2
Ziemniak, JA1
Quintiliani, R2
Krause, PJ1
Owens, NJ1
Nightingale, CH1
Roark, R1
Petrofski, J1
Berson, E1
Berman, S2
Barnett, ED1
Teele, DW1
Klein, JO1
Cabral, HJ1
Kharasch, SJ1
Pestalozza, G1
Romagnoli, M1
Tessitore, E1
Formica, U1
Grose, K1
Zerbe, GO1
Eichenwald, H1
Puhakka, H1
Haapaniemi, J1
Tuohimaa, P1
Ruuskanen, O1
Eskola, J1

Trials

8 trials available for sulfamethoxazole and Middle Ear Effusion

ArticleYear
Cotrimoxazole in the treatment of serous otitis. A follow-up report.
    The Journal of laryngology and otology, 1983, Volume: 97, Issue:3

    Topics: Child; Chlorpheniramine; Clinical Trials as Topic; Drug Combinations; Follow-Up Studies; Humans; Mul

1983
Antimicrobial therapy of chronic otitis media with effusion.
    International journal of pediatric otorhinolaryngology, 1984, Volume: 8, Issue:1

    Topics: Anti-Bacterial Agents; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Ear Canal; Ear

1984
A controlled trial of cotrimoxazole therapy in serous otitis media.
    The Journal of laryngology and otology, 1981, Volume: 95, Issue:10

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; H

1981
Sulphamethoxazole prophylaxis in the otitis-prone child.
    Archives of disease in childhood, 1982, Volume: 57, Issue:8

    Topics: Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Male; Otiti

1982
Practice variations among pediatricians and family physicians in the management of otitis media.
    Archives of pediatrics & adolescent medicine, 1995, Volume: 149, Issue:8

    Topics: Child, Preschool; Colorado; Decision Making; Family Practice; Humans; Infant; Male; Middle Ear Venti

1995
Comparison of ceftriaxone and trimethoprim-sulfamethoxazole for acute otitis media. Greater Boston Otitis Media Study Group.
    Pediatrics, 1997, Volume: 99, Issue:1

    Topics: Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Child, Preschool; Drug Therapy, Combination; Fem

1997
Medical management of chronic middle-ear effusion. Results of a clinical trial of prednisone combined with sulfamethoxazole and trimethoprim.
    American journal of diseases of children (1960), 1987, Volume: 141, Issue:6

    Topics: Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Combin

1987
Peroral prednisolone in the treatment of middle-ear effusion in children: a double-blind study.
    Auris, nasus, larynx, 1985, Volume: 12 Suppl 1

    Topics: Administration, Oral; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug C

1985

Other Studies

5 other studies available for sulfamethoxazole and Middle Ear Effusion

ArticleYear
Pathogenicity of Branhamella catarrhalis.
    Acta oto-laryngologica. Supplementum, 1984, Volume: 407

    Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Combinations; Drug Resistance, Microbial; Erythrom

1984
Penetration characteristics of trimethoprim-sulfamethoxazole in middle ear fluid of patients with chronic serous otitis media.
    The Journal of pediatrics, 1980, Volume: 96, Issue:6

    Topics: Child; Chronic Disease; Exudates and Transudates; Humans; Otitis Media; Otitis Media with Effusion;

1980
Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media.
    The Journal of infectious diseases, 1982, Volume: 145, Issue:6

    Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Drug Therapy, Combination; Ea

1982
[Diagnostic and therapeutic protocol in otitis media in the 1st year of life].
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 1988, Volume: 8 Suppl 19

    Topics: Acute Disease; Age Factors; Amoxicillin; Drug Combinations; Humans; Infant; Infant, Newborn; Middle

1988
Developments in diagnosing and treating otitis media.
    American family physician, 1985, Volume: 31, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Vaccines; Child; Child, Preschool; Drug Combinations; Hearing Disor

1985