sulfamethoxazole has been researched along with Malaria in 37 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Responses of parasitemia and fever in vivax malaria to standard doses of chloroquine and different dosage schedules of co-trimoxazole were compared in 165 children." | 9.05 | A comparative trial of oral chloroquine and oral co-trimoxazole in vivax malaria in children. ( Lal, H, 1982) |
| "6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine." | 7.67 | Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986) |
| "Patients with enteric fever confirmed by isolation of Salmonella species from blood culture, were treated with the combination of trimethoprim-sulphamethoxazole (co-trimoxazole)." | 7.66 | Trimethoprim-sulphamethoxazole in the treatment of enteric fever in the Sudan. ( Mekki, MO; Mukhtar, ED, 1981) |
| "Intermittent preventive treatment in pregnancy with sulfadoxine/pyrimethamine is contra-indicated in HIV-positive pregnant women receiving sulfamethoxazole/trimethoprim prophylaxis." | 5.22 | Pharmacokinetics of mefloquine and its effect on sulfamethoxazole and trimethoprim steady-state blood levels in intermittent preventive treatment (IPTp) of pregnant HIV-infected women in Kenya. ( Desai, M; González, R; Green, M; Kariuki, S; Katana, A; Menendez, C; Otieno, K; Ouma, P; Slutsker, L; ter Kuile, F, 2016) |
| "Responses of parasitemia and fever in vivax malaria to standard doses of chloroquine and different dosage schedules of co-trimoxazole were compared in 165 children." | 5.05 | A comparative trial of oral chloroquine and oral co-trimoxazole in vivax malaria in children. ( Lal, H, 1982) |
| "6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine." | 3.67 | Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986) |
| "Patients with enteric fever confirmed by isolation of Salmonella species from blood culture, were treated with the combination of trimethoprim-sulphamethoxazole (co-trimoxazole)." | 3.66 | Trimethoprim-sulphamethoxazole in the treatment of enteric fever in the Sudan. ( Mekki, MO; Mukhtar, ED, 1981) |
| "Two dosage schedules of co-trimoxazole, the standard antibacterial and a 2-day high-dose schedule, were compared with a standard course of chloroquine in the treatment of uncomplicated Plasmodium falciparum malaria." | 2.65 | An evaluation of co-trimoxazole in the treatment of Plasmodium falciparum malaria. ( Hansford, CF; Hoyland, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (81.08) | 18.7374 |
| 1990's | 2 (5.41) | 18.2507 |
| 2000's | 3 (8.11) | 29.6817 |
| 2010's | 2 (5.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hobbs, CV | 1 |
| Dixit, S | 1 |
| Penzak, SR | 1 |
| Sahu, T | 1 |
| Orr-Gonzalez, S | 1 |
| Lambert, L | 1 |
| Zeleski, K | 1 |
| Chen, J | 1 |
| Neal, J | 1 |
| Borkowsky, W | 1 |
| Wu, Y | 1 |
| Duffy, PE | 1 |
| Green, M | 1 |
| Otieno, K | 1 |
| Katana, A | 1 |
| Slutsker, L | 1 |
| Kariuki, S | 1 |
| Ouma, P | 1 |
| González, R | 1 |
| Menendez, C | 1 |
| ter Kuile, F | 1 |
| Desai, M | 1 |
| Hildenwall, H | 1 |
| Lindkvist, J | 2 |
| Tumwine, JK | 1 |
| Bergqvist, Y | 2 |
| Pariyo, G | 1 |
| Tomson, G | 1 |
| Peterson, S | 1 |
| Malm, M | 1 |
| Shann, F | 1 |
| Williams, GR | 1 |
| Law, TL | 1 |
| Kennedy, DH | 1 |
| Love, WC | 1 |
| Mukhtar, ED | 1 |
| Mekki, MO | 1 |
| Hansford, CF | 1 |
| Hoyland, J | 1 |
| Lal, H | 1 |
| Shanks, GD | 3 |
| Edstein, MD | 1 |
| Chedester, AL | 1 |
| Smith, CD | 1 |
| Corcoran, KD | 1 |
| Ngampochjana, M | 1 |
| Hansukjariya, P | 1 |
| Sattabongkot, J | 1 |
| Webster, HK | 1 |
| Bayly, AM | 1 |
| Macreadie, IG | 1 |
| Ansdell, VE | 1 |
| Wright, SG | 1 |
| Hutchinson, DB | 1 |
| Wormser, GP | 1 |
| Eichenlaub, D | 1 |
| Reimann, E | 1 |
| Bunjes, R | 1 |
| Neumann, S | 1 |
| Grahlow, WD | 1 |
| Duggan, MB | 1 |
| Beyer, L | 1 |
| Pechere, JC | 1 |
| Karwacki, JJ | 2 |
| Suriyamongkol, V | 1 |
| Watanasook, C | 1 |
| Singharaj, P | 1 |
| Hatton, CS | 1 |
| Peto, TE | 1 |
| Bunch, C | 1 |
| Pasvol, G | 1 |
| Russell, SJ | 1 |
| Singer, CR | 1 |
| Edwards, G | 1 |
| Winstanley, P | 1 |
| Barkakaty, BN | 1 |
| Sharma, GK | 1 |
| Chakravorty, NK | 1 |
| Yamaguchi, K | 1 |
| Koga, H | 1 |
| Kohno, S | 1 |
| Shigeno, Y | 1 |
| Suzuyama, Y | 1 |
| Hirota, M | 1 |
| Saito, A | 1 |
| Hara, K | 1 |
| Amagasaki, T | 1 |
| Iwanaga, S | 1 |
| Mittal, R | 1 |
| Chopra, A | 1 |
| Chopra, BK | 1 |
| Fleming, AF | 1 |
| Warrell, DA | 1 |
| Dickmeiss, H | 1 |
| Colwell, EJ | 3 |
| Peters, W | 1 |
| Hickman, RL | 1 |
| Kosakal, S | 1 |
| Wood, A | 1 |
| Wilkinson, RN | 1 |
| Neoypatimanond, S | 1 |
| Fasan, PO | 1 |
| Hitchings, GH | 1 |
| Heischkeil, R | 1 |
| Huys, J | 1 |
| Kayihigi, J | 1 |
| Freyens, P | 1 |
| Fowle, AS | 1 |
7 reviews available for sulfamethoxazole and Malaria
| Article | Year |
|---|---|
Trimethoprim-sulfamethoxazole. II. Clinical studies.
Topics: Bacterial Infections; Costs and Cost Analysis; Drug Combinations; Endocarditis, Bacterial; Female; H | 1978 |
Malaria prophylaxis during military operations in Thailand.
Topics: Animals; Antimalarials; Doxycycline; Drug Resistance; Humans; Malaria; Mefloquine; Military Personne | 1989 |
A review of the drug sensitivity of Plasmodium falciparum in Thailand.
Topics: Chloroquine; Drug Resistance; Geography; Humans; Malaria; Methylamines; Naphthacenes; Plasmodium fal | 1972 |
Summary of recent abstracts. 3. Malaria.2.
Topics: Animals; Carbon Isotopes; Chloroquine; Dapsone; DNA; Drug Resistance, Microbial; Humans; Malaria; Or | 1973 |
Folate antagonists as antibacterial and antiprotozoal agents.
Topics: Anti-Bacterial Agents; Antimalarials; Antiprotozoal Agents; Escherichia coli; Folic Acid Antagonists | 1971 |
Trimethoprim-sulphamethoxazole.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Drug Combinations; Evaluation Studies as Topic; Female; Fo | 1971 |
Trimethoprim-sulphamethoxazole.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Drug Combinations; Evaluation Studies as Topic; Female; Fo | 1971 |
6 trials available for sulfamethoxazole and Malaria
| Article | Year |
|---|---|
Pharmacokinetics of mefloquine and its effect on sulfamethoxazole and trimethoprim steady-state blood levels in intermittent preventive treatment (IPTp) of pregnant HIV-infected women in Kenya.
Topics: Adolescent; Adult; Antimalarials; Double-Blind Method; Female; HIV Infections; Humans; Kenya; Malari | 2016 |
An evaluation of co-trimoxazole in the treatment of Plasmodium falciparum malaria.
Topics: Adolescent; Adult; Antimalarials; Child; Dose-Response Relationship, Drug; Drug Combinations; Drug E | 1982 |
A comparative trial of oral chloroquine and oral co-trimoxazole in vivax malaria in children.
Topics: Administration, Oral; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Combinati | 1982 |
Proguanil/sulfamethoxazole malaria chemoprophy-laxis on the Thai-Cambodian border.
Topics: Adult; Animals; Cambodia; Dapsone; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male | 1991 |
Trimethoprim plus sulphamethoxazole compared with chloroquine in the treatment and suppression of malaria in African schoolchildren.
Topics: Africa; Child; Child, Preschool; Chloroquine; Drug Synergism; Female; Folic Acid Antagonists; Humans | 1971 |
Treatment of malaria with RO 6-2580.
Topics: Adolescent; Adult; Antimalarials; Female; Folic Acid Antagonists; Humans; Malaria; Male; Middle Aged | 1972 |
24 other studies available for sulfamethoxazole and Malaria
| Article | Year |
|---|---|
Neither the HIV protease inhibitor lopinavir-ritonavir nor the antimicrobial trimethoprim-sulfamethoxazole prevent malaria relapse in plasmodium cynomolgi-infected non-human primates.
Topics: Animals; Antimalarials; Female; HIV Protease Inhibitors; Lopinavir; Macaca mulatta; Malaria; Male; P | 2014 |
Low validity of caretakers' reports on use of selected antimalarials and antibiotics in children with severe pneumonia at an urban hospital in Uganda.
Topics: Anti-Infective Agents; Antimalarials; Caregivers; Child, Preschool; Chloroquine; Cross-Sectional Stu | 2009 |
Straightforward and rapid determination of sulfadoxine and sulfamethoxazole in capillary blood on sampling paper with liquid chromatography and UV detection.
Topics: Antimalarials; Blood Specimen Collection; Child, Preschool; Chromatography, Liquid; Health Education | 2009 |
Co-trimoxazole toxicity.
Topics: Antimalarials; Drug Combinations; Hemolysis; Humans; Infant; Infant, Newborn; Malaria; Sulfamethoxaz | 1984 |
Delayed diagnosis of malaria.
Topics: Child; Drug Combinations; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Sulfame | 1982 |
Trimethoprim-sulphamethoxazole in the treatment of enteric fever in the Sudan.
Topics: Adolescent; Adult; Drug Combinations; Female; Humans; Jaundice; Malaria; Male; Middle Aged; Sudan; S | 1981 |
Immunizations and chemoprophylaxis for travelers.
Topics: Diarrhea; Doxycycline; Humans; Immunization; Malaria; Preventive Medicine; Sulfamethoxazole; Travel; | 1981 |
Proguanil plus sulfamethoxazole is not causally prophylactic in the Macaca mulatta--Plasmodium cynomolgi model.
Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Liver; Macaca mulatta; Malaria; Male; Pl | 1994 |
Folic acid antagonism of sulfa drug treatments.
Topics: Animals; Antimalarials; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Malaria; Plasmo | 2002 |
Megaloblastic anaemia associated with combined pyrimethamine and co-trimoxazole administration.
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Combinations; Drug Therapy, Combination; Fema | 1976 |
[Tertian malaria in children and adults from an epidemic region in southern Turkey (author's transl)].
Topics: Adolescent; Adult; Appendicitis; Berlin; Child; Diagnosis, Differential; Disease Outbreaks; Female; | 1979 |
[Cholera today].
Topics: Acid-Base Equilibrium; Asia; Cholera; Dehydration; Diagnosis, Differential; Drug Combinations; Elect | 1979 |
Enteric fever in young Yoruba children.
Topics: Age Factors; Anemia; Arthritis, Infectious; Blood Transfusion; Child, Preschool; Chloramphenicol; Di | 1975 |
Combination chemotherapy of infectious diseases. Chairman's summing-up and conclusions.
Topics: Bacterial Infections; Bronchitis; Drug Combinations; Drug Evaluation; Dysentery, Bacillary; Female; | 1975 |
Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria.
Topics: Acute Disease; Adult; Agranulocytosis; Amodiaquine; Drug Combinations; Drug Therapy, Combination; Fe | 1986 |
Studies on efficacy of treatment with sulfamethoxazole + trimethoprim and sulfalene + pyrimethamine combinations in Plasmodium falciparum malaria of known and unknown resistant status.
Topics: Animals; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; India; Mala | 1988 |
[Clinical evaluation of SMX/TMP in treatment of patients with malaria].
Topics: Adult; Antimalarials; Drug Combinations; Humans; Malaria; Male; Plasmodium falciparum; Plasmodium vi | 1986 |
Co-trimoxazole in the treatment of malaria in psoriatics.
Topics: Drug Combinations; Humans; Malaria; Psoriasis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfame | 1986 |
Letter: Co-trimoxazole and the blood.
Topics: Administration, Oral; Adult; Anemia, Macrocytic; Blood Cell Count; Drug Therapy, Combination; Female | 1974 |
Quinine-tetracycline and quinine-bactrim treatment of acute falciparum malaria in Thailand.
Topics: Adolescent; Adult; Anti-Infective Agents; Blood; Child; Drug Combinations; Folic Acid Antagonists; H | 1973 |
Therapeutic screening to differentiate malaria from other tropical syndromes.
Topics: Diagnosis, Differential; Drug Combinations; Humans; Malaria; Mozambique; Plasmodium falciparum; Sulf | 1973 |
Letter: Effect of sulphamethoxazole-trimethoprim on the viability of Plasmodium falciparum gametocytes.
Topics: Adolescent; Adult; Anopheles; Female; Humans; Insect Vectors; Malaria; Male; Middle Aged; Plasmodium | 1973 |
[Criteria for the selection of sulfonamides for the treatment of rodent malaria (Plasmodium vinckei)].
Topics: Animals; Biomechanical Phenomena; Female; Malaria; Male; Mice; Mice, Inbred Strains; Oxazoles; Plasm | 1972 |
National use of trimethoprim and sulphamethoxazole for one year--problems and solutions.
Topics: Anti-Infective Agents; Bronchial Diseases; Brucellosis; Drug Synergism; Gonorrhea; Humans; Malaria; | 1970 |