Page last updated: 2024-11-04

sulfamethoxazole and Inflammation

sulfamethoxazole has been researched along with Inflammation in 12 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to determine the clinical value of triple antibiotic therapy consisting of doxycycline, compound sulfamethoxazole and rifampicin in the treatment of brucellosis spondylitis."8.02Clinical Effect of Doxycycline Combined with Compound Sulfamethoxazole and Rifampicin in the Treatment of Brucellosis Spondylitis. ( Jia, YL; Tian, Y; Yang, XM; Yao, Y; Yin, YL; Zhang, PN; Zhang, Y, 2021)
"The purpose of this study was to determine the clinical value of triple antibiotic therapy consisting of doxycycline, compound sulfamethoxazole and rifampicin in the treatment of brucellosis spondylitis."4.02Clinical Effect of Doxycycline Combined with Compound Sulfamethoxazole and Rifampicin in the Treatment of Brucellosis Spondylitis. ( Jia, YL; Tian, Y; Yang, XM; Yao, Y; Yin, YL; Zhang, PN; Zhang, Y, 2021)
" Adult wild-type (WT) and Cxcr2-/- mice were fed a diet supplemented with sulfamethoxazole/trimethoprim (SMZ/TMP) during pregnancy and lactation, and their pups were injected intraperitoneally with rhesus rotavirus (RRV) within 24 hours of life to induce experimental biliary atresia."3.85Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia. ( Bezerra, JA; Fei, L; Jee, J; Mourya, R; Shivakumar, P; Wagner, M, 2017)
"Gallic acid (GA) and its derivatives are anti-inflammatory agents reported to have an effect on osteoarthritis (OA)."3.81A Novel Synthesized Sulfonamido-Based Gallate-JEZ-C as Potential Therapeutic Agents for Osteoarthritis. ( Lin, C; Lin, X; Liu, B; Lu, Z; Wei, S; Zhao, J; Zheng, L; Zou, Y, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's5 (41.67)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Yang, XM1
Jia, YL1
Zhang, Y1
Zhang, PN1
Yao, Y1
Yin, YL1
Tian, Y1
Wang, Y2
Wang, D2
Yin, K2
Liu, Y2
Lu, H2
Zhao, H1
Xing, M2
Su, H1
Li, B1
Alexander, M1
Turnbaugh, PJ1
Wu, Z1
Lu, Z2
Ou, J1
Su, X1
Liu, J1
Jee, J1
Mourya, R1
Shivakumar, P1
Fei, L1
Wagner, M1
Bezerra, JA1
Wei, S1
Zou, Y1
Lin, X1
Lin, C1
Liu, B1
Zheng, L1
Zhao, J1
Cribb, AE1
McQuaid, T1
Renton, KW1
Friess, G1
Hirschfeld, E1
Komarov, FI1
Daniliak, IG1
Guliaev, FE1
Romashova, NI1
Verenchikova, IaV1
Wawryk, R1
Krupa, B1
Nawrocki, W1

Other Studies

12 other studies available for sulfamethoxazole and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Clinical Effect of Doxycycline Combined with Compound Sulfamethoxazole and Rifampicin in the Treatment of Brucellosis Spondylitis.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Adult; Brucellosis; Doxycycline; Drug Therapy, Combination; Female; Humans; Inflammation; Low Back P

2021
Lycopene attenuates oxidative stress, inflammation, and apoptosis by modulating Nrf2/NF-κB balance in sulfamethoxazole-induced neurotoxicity in grass carp (Ctenopharyngodon Idella).
    Fish & shellfish immunology, 2022, Volume: 121

    Topics: Animal Feed; Animals; Apoptosis; Brain Injuries; Carps; Diet; Fish Proteins; Inflammation; Lycopene;

2022
NLRP3 inflammasome is involved in the mechanism of the mitigative effect of lycopene on sulfamethoxazole-induced inflammatory damage in grass carp kidneys.
    Fish & shellfish immunology, 2022, Volume: 123

    Topics: Animals; Anti-Bacterial Agents; Carps; Inflammasomes; Inflammation; Kidney; Lycopene; NLR Family, Py

2022
Stressed-out gut bacteria are pterin up gut inflammation.
    Nature microbiology, 2020, Volume: 5, Issue:11

    Topics: Antioxidants; Bacteria; Escherichia coli; Gastrointestinal Microbiome; Humans; Inflammation; Pharmac

2020
Inflammatory response and oxidative stress attenuated by sulfiredoxin‑1 in neuron‑like cells depends on nuclear factor erythroid‑2‑related factor 2.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Animals; Antioxidants; Cell Survival; Gene Expression Regulation; Heme Oxygenase-1; Inflammation; Li

2020
Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Animals; Bile Ducts; Biliary Atresia; Disease Models, Animal; Female; Gene Expression Profiling; Inf

2017
A Novel Synthesized Sulfonamido-Based Gallate-JEZ-C as Potential Therapeutic Agents for Osteoarthritis.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Antioxidants; Cartilage, Articular; Cell Line; Chondrocytes; Gallic Acid; Humans; Inflammation; Oste

2015
Effect of lipopolysaccharide (LPS)-evoked host defense activation on hepatic microsomal formation and reduction of sulfamethoxazole hydroxylamine in the rat.
    Biochemical pharmacology, 2001, Aug-15, Volume: 62, Issue:4

    Topics: Animals; Inflammation; Lipopolysaccharides; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases;

2001
[Allergic vasculitis with arthritis due to bactrim allergy (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1977, Jul-15, Volume: 119, Issue:28

    Topics: Aged; Arthritis; Blood Coagulation; Blood Platelets; Bronchitis; Drug Combinations; Drug Hypersensit

1977
[Use of preparations containing sulfanilamides and trimethoprim for treatment of inflammatory respiratory diseases].
    Klinicheskaia meditsina, 1976, Volume: 54, Issue:11

    Topics: Adolescent; Adult; Aged; Drug Combinations; Female; Humans; Inflammation; Lung Diseases; Male; Middl

1976
[Evaluation of Septrin in the treatment of inflammatory diseases in obstetrics and gynecology].
    Ginekologia polska, 1972, Volume: 43, Issue:8

    Topics: Adult; Anti-Infective Agents; Evaluation Studies as Topic; Female; Folic Acid Antagonists; Genital D

1972