Page last updated: 2024-11-04

sulfamethoxazole and HIV

sulfamethoxazole has been researched along with HIV in 5 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.

Research Excerpts

ExcerptRelevanceReference
"Trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis in HIV-uninfected, exposed (HUE) children variably reduces clinical malaria burden despite antifolate resistance, but data regarding achieved serum levels and adherence are lacking."7.88Sulfamethoxazole Levels in HIV-Exposed Uninfected Ugandan Children. ( Anok, A; Duffy, PE; Eastman, RT; Gabriel, EE; Hobbs, CV; Kasule, J; Neal, J; Newell, K; Penzak, S; Reynolds, SJ; Serwadda, D, 2018)
"Hypersensitivity adverse drug reactions are much more common among patients with acquired immunodeficiency syndrome (AIDS) than in the general population."5.33Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro. ( Dekaban, GA; Rieder, MJ; Wijsman, JA, 2005)
"Trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis in HIV-uninfected, exposed (HUE) children variably reduces clinical malaria burden despite antifolate resistance, but data regarding achieved serum levels and adherence are lacking."3.88Sulfamethoxazole Levels in HIV-Exposed Uninfected Ugandan Children. ( Anok, A; Duffy, PE; Eastman, RT; Gabriel, EE; Hobbs, CV; Kasule, J; Neal, J; Newell, K; Penzak, S; Reynolds, SJ; Serwadda, D, 2018)
"Hypersensitivity adverse drug reactions are much more common among patients with acquired immunodeficiency syndrome (AIDS) than in the general population."1.33Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro. ( Dekaban, GA; Rieder, MJ; Wijsman, JA, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Washino, T1
Mikita, K1
Kosaka, A1
Sakamoto, N1
Iwabuchi, S1
Nakamura-Uchiyama, F1
Kasule, J1
Gabriel, EE1
Anok, A1
Neal, J1
Eastman, RT1
Penzak, S1
Newell, K1
Serwadda, D1
Duffy, PE1
Reynolds, SJ1
Hobbs, CV1
Wei, KC1
Sy, C1
Wu, SY1
Chuang, TJ1
Huang, WC1
Lai, PC1
Wijsman, JA1
Dekaban, GA1
Rieder, MJ1
Blossom, DB1
Namayanja-Kaye, G1
Nankya-Mutyoba, J1
Mukasa, JB1
Bakka, H1
Rwambuya, S1
Windau, A1
Bajaksouzian, S1
Walker, CJ1
Joloba, ML1
Kityo, C1
Mugyenyi, P1
Whalen, CC1
Jacobs, MR1
Salata, RA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Trimethoprim-sulfamethoxazole Prophylaxis on Malaria Infection and Immunity in Children in Uganda[NCT02094508]173 participants (Actual)Observational2014-03-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for sulfamethoxazole and HIV

ArticleYear
Disseminated Toxoplasmosis associated with Haemophagocytic Lymphohistiocytosis in a Patient with the Human Immunodeficiency Virus: A Case Report and Literature Review.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022, Volume: 123

    Topics: Adult; Clindamycin; Female; HIV; HIV Infections; Humans; Lymphohistiocytosis, Hemophagocytic; Sulfam

2022

Other Studies

4 other studies available for sulfamethoxazole and HIV

ArticleYear
Sulfamethoxazole Levels in HIV-Exposed Uninfected Ugandan Children.
    The American journal of tropical medicine and hygiene, 2018, Volume: 98, Issue:6

    Topics: Anti-Retroviral Agents; Antimalarials; Drug Resistance; Female; Folic Acid Antagonists; HIV; HIV Inf

2018
Pneumocystis jirovecii pneumonia in HIV-uninfected, rituximab treated non-Hodgkin lymphoma patients.
    Scientific reports, 2018, 05-29, Volume: 8, Issue:1

    Topics: Adult; Aged; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamid

2018
Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:3

    Topics: Animals; Anti-Infective Agents; Biotransformation; Cell Line; Cell Survival; Clindamycin; Coculture

2005
Oropharyngeal colonization by Streptococcus pneumoniae among HIV-infected adults in Uganda: assessing prevalence and antimicrobial susceptibility.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2006, Volume: 10, Issue:6

    Topics: Adult; Ambulatory Care Facilities; Anti-Infective Agents; Carrier State; Cross-Sectional Studies; Dr

2006