sulfamethoxazole has been researched along with Disease Models, Animal in 43 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
Excerpt | Relevance | Reference |
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"The prophylactic effect of in-feed medication of conventional pigs with sulphadimethoxine (SDM), sulphamethoxazole (SMX), and trimethoprim (TMP) was tested by using an Actinobacillus pleuropneumoniae infection model." | 7.70 | Prevention of pleuropneumonia in pigs by in-feed medication with sulphadimethoxine and sulphamethoxazole in combination with trimethoprim. ( Kuiper, HA; Mengelers, MJ; Pijpers, A; van Miert, AS; Verheijden, JH, 2000) |
"Co-trimazine, a new combination of trimethoprim and sulphadiazine intended for treatment of urinary tract infections, was tested and compared to co-trimoxazole in an experimental model of acute, obstructive pyelonephritis in the rat." | 7.66 | Efficacy of two trimethoprim-sulphonamide combinations in experimental pyelonephritis in the rat. ( Ritzerfeld, W, 1979) |
" Adult wild-type (WT) and Cxcr2-/- mice were fed a diet supplemented with sulfamethoxazole/trimethoprim (SMZ/TMP) during pregnancy and lactation, and their pups were injected intraperitoneally with rhesus rotavirus (RRV) within 24 hours of life to induce experimental biliary atresia." | 3.85 | Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia. ( Bezerra, JA; Fei, L; Jee, J; Mourya, R; Shivakumar, P; Wagner, M, 2017) |
"The prophylactic effect of in-feed medication of conventional pigs with sulphadimethoxine (SDM), sulphamethoxazole (SMX), and trimethoprim (TMP) was tested by using an Actinobacillus pleuropneumoniae infection model." | 3.70 | Prevention of pleuropneumonia in pigs by in-feed medication with sulphadimethoxine and sulphamethoxazole in combination with trimethoprim. ( Kuiper, HA; Mengelers, MJ; Pijpers, A; van Miert, AS; Verheijden, JH, 2000) |
"Co-trimazine, a new combination of trimethoprim and sulphadiazine intended for treatment of urinary tract infections, was tested and compared to co-trimoxazole in an experimental model of acute, obstructive pyelonephritis in the rat." | 3.66 | Efficacy of two trimethoprim-sulphonamide combinations in experimental pyelonephritis in the rat. ( Ritzerfeld, W, 1979) |
"The results of the treatment of chronic bacterial prostatitis are disappointing." | 2.36 | Chronic bacterial prostatitis: theoretical and experimental considerations. ( Iversen, P; Jensen, KM; Madsen, PO, 1983) |
" Testing of biological activity revealed limited potential for resistance to these agents, low toxicity, and highly effective in vivo activity, even with low dosing regimens." | 1.40 | Antibacterial activity of a series of N2,N4-disubstituted quinazoline-2,4-diamines. ( Burda, WN; Fleeman, R; Manetsch, R; Shaw, LN; Van Horn, KS, 2014) |
"Thirty-four privately owned sulphonamide HS dogs, 10 sulphonamide-'tolerant' dogs, 18 sulphonamide-naïve dogs, and four dogs experimentally dosed with SMX and the oxidative metabolite SMX-nitroso, were tested for drug-serum adducts by immunoblotting, and anti-drug antibodies by ELISA." | 1.33 | Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity. ( Danhof, RS; Lavergne, SN; Trepanier, LA; Volkman, EM, 2006) |
" Extending these experiments, we have now shown that roxithromycin at doses of 400 or 200 mg/kg/day combined with dapsone at doses of 5, 25 or 50 mg/kg/day completely prevented the development of T." | 1.30 | Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model. ( Brun-Pascaud, M; Chau, F; Derouin, F; Girard, PM, 1998) |
" In the chronic cystogenic murine models, the combination TMP plus SMX administered from day 5 for 15 days or from day 28 for 288 days, gave protection and even apparent toxoplasmal eradication ('cure') at the highest dosing (60/300 mg/kg per day)." | 1.30 | Evaluation of trimethoprim and sulphamethoxazole as monotherapy or in combination in the management of toxoplasmosis in murine models. ( Dumas, JL; Pechère, JC; Pizzolato, G, 1999) |
"Trimethoprim K values were also not affected by model testing sequence (p = 0/760), but were by model type (p = 0." | 1.29 | Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics. ( Canafax, DM; Erdmann, GR; Giebink, GS; Le, CT; Lovdahl, MJ; Russlie, H, 1994) |
" Ro 11-8958, TMP, and diaveridine used at a dosage of 20 mg/kg/day with SMX were only slightly more effective than SMX used alone." | 1.29 | Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis. ( Foy, J; Steele, P; Walzer, PD; White, M, 1993) |
"Pneumocystis carinii pneumonia is a major cause of death in AIDS patients in the United States." | 1.28 | Treatment of Pneumocystis carinii pneumonia with 1,3-beta-glucan synthesis inhibitors. ( Fromtling, RA; Nollstadt, KH; Pittarelli, LA; Romancheck, MA; Schmatz, DM; Schwartz, RE; Turner, MJ; Vanmiddlesworth, FL; Wilson, KE, 1990) |
"Antimicrobial treatment of otitis media, especially drug dosing considerations, is largely empiric, with few reported pharmacologic studies of drug distribution into the middle ear." | 1.28 | Experimental animal models for studying antimicrobial pharmacokinetics in otitis media. ( Canafax, DM; Erdmann, GR; Giebink, GS; Juhn, SK; Le, CT; Nonomura, N, 1989) |
"The purpose of this study was to identify new drugs for the prevention and treatment of Pneumocystis carinii pneumonitis (PCP) induced in rats by continuous daily dosage with dexamethasone." | 1.27 | Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis. ( Hughes, WT; Smith, BL, 1984) |
"Suramin and dapsone were weakly active." | 1.27 | Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia. ( Clarkson, AB; Rosenberg, C; Williams, DE, 1988) |
"Pentamidine was administered three times weekly via a Bird micronebulizer." | 1.27 | Pentamidine aerosol in prophylaxis and treatment of murine Pneumocystis carinii pneumonia. ( Brun-Pascaud, M; Farinotti, R; Girard, PM; Kernbaum, S; Tamisier, L, 1987) |
"Norfloxacin was substantially more effective than trimethoprim-sulphamethoxazole in reducing the number of colony forming units from kidney homogenates when the test animals were diabetic." | 1.27 | Norfloxacin versus trimethoprim-sulphamethoxazole: efficacy in a model of ascending urinary tract infection in normal and streptozotocin-induced diabetic mice. ( Abruzzo, GK; Fromtling, RA; Gadebusch, HH; Gilfillan, EC; Pelak, BA, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (48.84) | 18.7374 |
1990's | 9 (20.93) | 18.2507 |
2000's | 4 (9.30) | 29.6817 |
2010's | 6 (13.95) | 24.3611 |
2020's | 3 (6.98) | 2.80 |
Authors | Studies |
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Van Horn, KS | 1 |
Burda, WN | 1 |
Fleeman, R | 1 |
Shaw, LN | 1 |
Manetsch, R | 1 |
Abrams, RPM | 1 |
Yasgar, A | 1 |
Teramoto, T | 1 |
Lee, MH | 1 |
Dorjsuren, D | 1 |
Eastman, RT | 1 |
Malik, N | 1 |
Zakharov, AV | 1 |
Li, W | 1 |
Bachani, M | 1 |
Brimacombe, K | 1 |
Steiner, JP | 1 |
Hall, MD | 1 |
Balasubramanian, A | 1 |
Jadhav, A | 1 |
Padmanabhan, R | 1 |
Simeonov, A | 1 |
Nath, A | 1 |
Ang, CW | 1 |
Lee, BM | 1 |
Jackson, CJ | 1 |
Wang, Y | 3 |
Franzblau, SG | 1 |
Francisco, AF | 1 |
Kelly, JM | 1 |
Bernhardt, PV | 1 |
Tan, L | 1 |
West, NP | 1 |
Sykes, ML | 1 |
Hinton, AO | 1 |
Bolisetti, R | 1 |
Avery, VM | 1 |
Cooper, MA | 1 |
Blaskovich, MAT | 1 |
Karpińska, G | 1 |
Dobrowolski, JC | 1 |
Yinda, CK | 1 |
Rector, A | 1 |
Zeller, M | 1 |
Conceição-Neto, N | 1 |
Heylen, E | 1 |
Maes, P | 1 |
Ghogomu, SM | 1 |
Van Ranst, M | 1 |
Matthijnssens, J | 1 |
Arthanari, SK | 1 |
Vanitha, J | 1 |
Ganesh, M | 1 |
Venkateshwaran, K | 1 |
de Lama Caro-Patón, G | 1 |
García-Salido, A | 1 |
Iglesias-Bouzas, MI | 1 |
Guillén, M | 1 |
Cañedo-Villaroya, E | 1 |
Martínez-Romera, I | 1 |
Serrano-González, A | 1 |
Casado-Flores, J | 1 |
Gale, P | 2 |
Chen, X | 2 |
Li, H | 1 |
Lucero-Prisno, DE | 1 |
Abdullah, AS | 1 |
Huang, J | 1 |
Laurence, C | 1 |
Liang, X | 1 |
Ma, Z | 1 |
Mao, Z | 1 |
Ren, R | 1 |
Wu, S | 1 |
Wang, N | 1 |
Wang, P | 2 |
Wang, T | 1 |
Yan, H | 1 |
Zou, Y | 1 |
Olsen, KM | 1 |
Gabler, NK | 1 |
Rademacher, CJ | 1 |
Schwartz, KJ | 1 |
Schweer, WP | 1 |
Gourley, GG | 1 |
Patience, JF | 1 |
Rauch, JC | 1 |
Stokes, RS | 1 |
Shike, DW | 1 |
Luebbe, KM | 1 |
Stalker, LA | 1 |
Klopfenstein, TJ | 1 |
Funston, RN | 1 |
Unger, PA | 1 |
Lighaam, LC | 1 |
Vermeulen, E | 1 |
Kruithof, S | 1 |
Makuch, M | 1 |
Culver, EL | 1 |
van Bruggen, R | 1 |
Remmerswaal, EBM | 1 |
Ten Berge, IJM | 1 |
Emmens, RW | 1 |
Niessen, HWM | 1 |
Barnes, E | 1 |
Wolbink, GJ | 1 |
van Ham, SM | 1 |
Rispens, T | 1 |
Liang, JX | 1 |
Lin, J | 1 |
Liu, J | 1 |
Wang, X | 1 |
Zhang, T | 1 |
Li, J | 1 |
Wu, Y | 2 |
Venier, M | 1 |
Salamova, A | 1 |
Gonçales, VR | 1 |
Lian, J | 1 |
Gautam, S | 1 |
Tilley, RD | 1 |
Gooding, JJ | 1 |
Kandel, YR | 1 |
Bradley, CA | 1 |
Chilvers, MI | 1 |
Mathew, FM | 1 |
Tenuta, AU | 1 |
Smith, DL | 1 |
Wise, KA | 1 |
Mueller, DS | 1 |
Lu, N | 1 |
Lu, M | 1 |
Liu, P | 1 |
Xu, H | 1 |
Qiu, X | 1 |
Hu, S | 1 |
Bai, S | 1 |
Wu, J | 1 |
Xue, S | 1 |
Dai, X | 1 |
Dharmage, SC | 1 |
Abramson, MJ | 1 |
Erbas, B | 1 |
Bennett, CM | 1 |
Svanes, C | 1 |
Hui, J | 1 |
Axelrad, C | 1 |
Lowe, AJ | 1 |
Lodge, CJ | 1 |
Hoshi, M | 1 |
Osawa, Y | 1 |
Nakamoto, K | 1 |
Morita, N | 1 |
Yamamoto, Y | 1 |
Ando, T | 1 |
Tashita, C | 1 |
Nabeshima, T | 1 |
Saito, K | 1 |
Gianesello, L | 1 |
Del Prete, D | 1 |
Ceol, M | 1 |
Priante, G | 1 |
Calò, LA | 1 |
Anglani, F | 1 |
Vekaria, HJ | 1 |
Hubbard, WB | 1 |
Scholpa, NE | 1 |
Spry, ML | 1 |
Gooch, JL | 1 |
Prince, SJ | 1 |
Schnellmann, RG | 1 |
Sullivan, PG | 1 |
Zhang, Q | 1 |
Hu, R | 1 |
Gu, Z | 1 |
Zhang, M | 1 |
Zhang, Z | 1 |
Peng, Y | 1 |
Feng, L | 1 |
Li, X | 4 |
Zhao, C | 1 |
Sarfaraz, K | 1 |
Gao, L | 1 |
Wang, H | 1 |
Wan, C | 1 |
Leng, J | 1 |
Yang, P | 1 |
Gao, X | 1 |
Gao, J | 1 |
Emam, HE | 1 |
Saad, NM | 1 |
Abdallah, AEM | 1 |
Ahmed, HB | 1 |
Palombo, M | 1 |
Ianus, A | 1 |
Guerreri, M | 1 |
Nunes, D | 1 |
Alexander, DC | 1 |
Shemesh, N | 1 |
Zhang, H | 1 |
Xiong, Q | 1 |
Liu, YS | 1 |
Hu, LX | 1 |
Shi, ZQ | 1 |
Ying, GG | 1 |
Chen, R | 1 |
Hong, X | 1 |
Yan, S | 1 |
Zha, J | 1 |
Gu, H | 1 |
Zhong, Q | 1 |
Zeng, Y | 1 |
Zhang, S | 1 |
Bu, Y | 1 |
Farghali, M | 1 |
Mayumi, M | 1 |
Syo, K | 1 |
Satoshi, A | 1 |
Seiichi, Y | 1 |
Takashima, S | 1 |
Ono, H | 1 |
Ap, Y | 1 |
Yamashiro, T | 1 |
Ahmed, MM | 1 |
Kotb, S | 1 |
Iwasaki, M | 1 |
Ihara, I | 1 |
Umetsu, K | 1 |
Hu, B | 1 |
Quan, J | 1 |
Huang, K | 1 |
Gu, X | 1 |
Zhu, J | 1 |
Yan, Y | 1 |
Wu, P | 1 |
Yang, L | 1 |
Zhao, J | 1 |
Koók, L | 1 |
Nemestóthy, N | 1 |
Bélafi-Bakó, K | 1 |
Bakonyi, P | 1 |
Luo, X | 1 |
Zhang, F | 1 |
Li, Q | 1 |
Xia, Q | 1 |
Li, Z | 1 |
Ye, W | 1 |
Li, S | 1 |
Ge, C | 1 |
Zakkula, A | 1 |
Pulipati, S | 1 |
Dittakavi, S | 1 |
Bestha, RM | 1 |
Zainuddin, M | 1 |
Trivedi, RK | 1 |
Mullangi, R | 1 |
Lo, GH | 1 |
Lin, CW | 1 |
Tai, CM | 1 |
Perng, DS | 1 |
Chen, IL | 1 |
Yeh, JH | 1 |
Lin, HC | 1 |
Rocha, GS | 1 |
Silva, MKL | 1 |
Cesarino, I | 1 |
Hazzaa, SM | 1 |
Abdelaziz, SAM | 1 |
Abd Eldaim, MA | 1 |
Abdel-Daim, MM | 1 |
Elgarawany, GE | 1 |
Larsson, P | 1 |
Ljuslinder, I | 1 |
Öhlund, D | 1 |
Myte, R | 1 |
Löfgren-Burström, A | 1 |
Zingmark, C | 1 |
Ling, A | 1 |
Edin, S | 1 |
Palmqvist, R | 1 |
Murthi, P | 1 |
Rajaraman, G | 1 |
Erwich, JJHM | 1 |
Dimitriadis, E | 1 |
Yoon, HG | 1 |
Oh, D | 1 |
Ahn, YC | 1 |
Noh, JM | 1 |
Pyo, H | 1 |
Cho, WK | 1 |
Song, YM | 1 |
Park, M | 1 |
Hwang, NY | 1 |
Sun, JM | 1 |
Kim, HK | 1 |
Zo, JI | 1 |
Shim, YM | 1 |
Persano, A | 1 |
Quaranta, F | 1 |
Taurino, A | 1 |
Siciliano, PA | 1 |
Iannacci, J | 1 |
Malekbala, MR | 1 |
Soltani, S | 1 |
Abdul Rashid, S | 1 |
Abdullah, LC | 1 |
Rashid, U | 1 |
Nehdi, IA | 1 |
Choong, TSY | 1 |
Teo, SH | 1 |
Xu, P | 1 |
Yan, F | 1 |
Zhao, Y | 1 |
Sun, S | 1 |
Ying, L | 1 |
Quinzi, V | 1 |
Caruso, S | 1 |
Mummolo, S | 1 |
Nota, A | 1 |
Angelone, AM | 1 |
Mattei, A | 1 |
Gatto, R | 1 |
Marzo, G | 1 |
Xin, W | 1 |
Severino, J | 1 |
Venkert, A | 1 |
Yu, H | 1 |
Knorr, D | 1 |
Yang, JM | 1 |
Carlson, L | 1 |
Hicks, R | 1 |
De Rosa, I | 1 |
Beckmann, NA | 1 |
Bitsch, RG | 1 |
Schonhoff, M | 1 |
Siebenrock, KA | 1 |
Schwarze, M | 1 |
Jaeger, S | 1 |
Jee, J | 1 |
Mourya, R | 1 |
Shivakumar, P | 1 |
Fei, L | 1 |
Wagner, M | 1 |
Bezerra, JA | 1 |
Eldesouky, HE | 1 |
Abutaleb, NS | 1 |
Mohammad, H | 1 |
Seleem, MN | 1 |
Simon, V | 1 |
K V, S | 1 |
Sasikumar, R | 1 |
Kanthlal, SK | 1 |
Belal, US | 2 |
Norose, K | 2 |
Mohamed, RM | 2 |
Sekine, S | 1 |
Nukaga, T | 1 |
Ito, K | 1 |
Abdellatif, MZ | 1 |
Abdelgelil, NH | 1 |
Yano, A | 2 |
Bougie, DW | 1 |
Nayak, D | 1 |
Boylan, B | 1 |
Newman, PJ | 1 |
Aster, RH | 1 |
Aosai, F | 1 |
Mun, HS | 1 |
Ahmed, AK | 1 |
Chen, M | 1 |
Piao, LX | 1 |
Iwakura, Y | 1 |
Lavergne, SN | 1 |
Danhof, RS | 1 |
Volkman, EM | 1 |
Trepanier, LA | 1 |
Hughes, WT | 2 |
Smith, BL | 1 |
Madsen, PO | 1 |
Jensen, KM | 1 |
Iversen, P | 1 |
Killmar, JT | 1 |
Oz, HS | 1 |
Alder, J | 1 |
Hutch, T | 1 |
Meulbroek, JA | 1 |
Clement, JC | 1 |
Canafax, DM | 2 |
Russlie, H | 1 |
Lovdahl, MJ | 1 |
Erdmann, GR | 2 |
Le, CT | 2 |
Giebink, GS | 2 |
Shanks, GD | 1 |
Edstein, MD | 1 |
Chedester, AL | 1 |
Smith, CD | 1 |
Corcoran, KD | 1 |
Ngampochjana, M | 1 |
Hansukjariya, P | 1 |
Sattabongkot, J | 1 |
Webster, HK | 1 |
Walzer, PD | 1 |
Foy, J | 1 |
Steele, P | 1 |
White, M | 1 |
Yeo, AE | 1 |
Brun-Pascaud, M | 2 |
Chau, F | 1 |
Derouin, F | 1 |
Girard, PM | 2 |
Dumas, JL | 1 |
Pizzolato, G | 1 |
Pechère, JC | 1 |
Mengelers, MJ | 1 |
Kuiper, HA | 1 |
Pijpers, A | 1 |
Verheijden, JH | 1 |
van Miert, AS | 1 |
Choquet-Kastylevsky, G | 1 |
Santolaria, N | 1 |
Tedone, R | 1 |
Aujoulat, M | 1 |
Descotes, J | 1 |
Dhondt, JL | 2 |
Farriaux, JP | 2 |
Dautrevaux, M | 1 |
Biserte, G | 1 |
Hamilton-Miller, JM | 1 |
Ritzerfeld, W | 2 |
Schmatz, DM | 1 |
Romancheck, MA | 1 |
Pittarelli, LA | 1 |
Schwartz, RE | 1 |
Fromtling, RA | 2 |
Nollstadt, KH | 1 |
Vanmiddlesworth, FL | 1 |
Wilson, KE | 1 |
Turner, MJ | 1 |
Nonomura, N | 1 |
Juhn, SK | 1 |
Bartlett, MS | 1 |
Durkin, MM | 1 |
Jay, MA | 1 |
Queener, SF | 1 |
Smith, JW | 1 |
Pueschel, SM | 1 |
Boylan, J | 1 |
Ellenbogen, R | 1 |
Clarkson, AB | 1 |
Williams, DE | 1 |
Rosenberg, C | 1 |
Muhvich, KH | 1 |
Myers, RA | 1 |
Marzella, L | 1 |
Domer, JE | 1 |
Hector, RF | 1 |
Farinotti, R | 1 |
Tamisier, L | 1 |
Kernbaum, S | 1 |
Abruzzo, GK | 1 |
Gilfillan, EC | 1 |
Pelak, BA | 1 |
Gadebusch, HH | 1 |
Kawaler, B | 1 |
Hof, H | 1 |
Vischer, WA | 1 |
Prát, V | 1 |
Hatala, M | 1 |
Konícková, L | 1 |
Van der Waaij, D | 1 |
Cohen, BJ | 1 |
Anver, MR | 1 |
Philippon, A | 1 |
Kazmierczak, A | 1 |
Névot, P | 1 |
Burrous, SE | 1 |
Cawein, JB | 1 |
Roy, AD | 1 |
Cameron, HM | 1 |
3 reviews available for sulfamethoxazole and Disease Models, Animal
Article | Year |
---|---|
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am | 2013 |
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am | 2013 |
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am | 2013 |
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am | 2013 |
Chronic bacterial prostatitis: theoretical and experimental considerations.
Topics: Animals; Antibody Formation; Antibody-Coated Bacteria Test, Urinary; Bacterial Infections; Chronic D | 1983 |
Antimicrobial agents acting against anaerobes.
Topics: Aminoglycosides; Anaerobiosis; Animals; Anti-Bacterial Agents; Bacteria; Chloramphenicol; Clindamyci | 1975 |
1 trial available for sulfamethoxazole and Disease Models, Animal
40 other studies available for sulfamethoxazole and Disease Models, Animal
Article | Year |
---|---|
Antibacterial activity of a series of N2,N4-disubstituted quinazoline-2,4-diamines.
Topics: Animals; Anti-Bacterial Agents; Diamines; Disease Models, Animal; Hemolysis; Humans; Larva; Microbia | 2014 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Nitroimidazopyrazinones with Oral Activity against Tuberculosis and Chagas Disease in Mouse Models of Infection.
Topics: Animals; Chagas Disease; Disease Models, Animal; Mice; Mycobacterium tuberculosis; Nitroimidazoles; | 2022 |
Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia.
Topics: Animals; Bile Ducts; Biliary Atresia; Disease Models, Animal; Female; Gene Expression Profiling; Inf | 2017 |
Synergistic interactions of sulfamethoxazole and azole antifungal drugs against emerging multidrug-resistant Candida auris.
Topics: Animals; Antifungal Agents; Caenorhabditis elegans; Candida; Candidiasis; Disease Models, Animal; Dr | 2018 |
In Vitro Protective Effect of Ascorbic Acid Against Antibiotic-Induced Hepatotoxicity.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cell Survival; Chemical and Drug Induce | 2020 |
Quantitative assessment of the effects of sulfamethoxazole on Toxoplasma gondii loads in susceptible WT C57BL/6 mice as an immunocompetent host model.
Topics: Animals; Brain; Coccidiostats; Disease Models, Animal; DNA, Protozoan; Heart; Immunocompetence; Lung | 2016 |
Drug-dependent clearance of human platelets in the NOD/scid mouse by antibodies from patients with drug-induced immune thrombocytopenia.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Antibodies; Antibodies, Monoclonal; Blood | 2010 |
Evaluation of the effects of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-gamma knockout mice using QC-PCR.
Topics: Animals; Disease Models, Animal; Interferon-gamma; Mice; Mice, Inbred BALB C; Mice, Knockout; Revers | 2004 |
Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity.
Topics: Animals; Anti-Infective Agents; Antibody Specificity; Blood Proteins; Cross Reactions; Disease Model | 2006 |
Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis.
Topics: Animals; Dapsone; Disease Models, Animal; Drug Combinations; Male; Pneumonia, Pneumocystis; Rats; Ra | 1984 |
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Tria | 1994 |
Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine.
Topics: AIDS-Related Opportunistic Infections; Animals; Clarithromycin; Disease Models, Animal; Dose-Respons | 1994 |
Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics.
Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Chinchilla; Diffusion; Disease Models, Animal; Ear, Mid | 1994 |
Proguanil plus sulfamethoxazole is not causally prophylactic in the Macaca mulatta--Plasmodium cynomolgi model.
Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Liver; Macaca mulatta; Malaria; Male; Pl | 1994 |
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis.
Topics: AIDS-Related Opportunistic Infections; Animals; Dapsone; Disease Models, Animal; Dose-Response Relat | 1993 |
Direct comparison of antimalarial activity among PS-15 combination therapies by bioassay of serum samples from treated Saimiri sciureus.
Topics: Animals; Antimalarials; Atovaquone; Biological Assay; Dapsone; Disease Models, Animal; Drug Synergis | 1997 |
Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Disease Models, Animal; Dose-Respons | 1998 |
Evaluation of trimethoprim and sulphamethoxazole as monotherapy or in combination in the management of toxoplasmosis in murine models.
Topics: Animals; Chronic Disease; Disease Models, Animal; Drug Evaluation; Mice; Sulfamethoxazole; Toxoplasm | 1999 |
Prevention of pleuropneumonia in pigs by in-feed medication with sulphadimethoxine and sulphamethoxazole in combination with trimethoprim.
Topics: Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animal Feed; Animals; Anti-Bacterial Age | 2000 |
Induction of delayed-type hypersensitivity to sulfamethoxazole in mice: role of metabolites.
Topics: Animals; Anti-Infective Agents; CD4 Lymphocyte Count; Disease Models, Animal; Drug Hypersensitivity; | 2001 |
Study of blood aminoacids in experimental hyperphenylalaninemia.
Topics: Amino Acids; Animals; Disease Models, Animal; Fenclonine; Humans; Male; Phenylalanine; Phenylketonur | 1977 |
A new experimental model of hyperphenylalaninemia in rat. Effect of p-chlorophenylalanine and cotrimoxazole.
Topics: Animals; Disease Models, Animal; Drug Combinations; Fenclonine; Humans; Kidney; Liver; Male; Phenyla | 1977 |
Efficacy of two trimethoprim-sulphonamide combinations in experimental pyelonephritis in the rat.
Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Escherichia coli I | 1979 |
Treatment of Pneumocystis carinii pneumonia with 1,3-beta-glucan synthesis inhibitors.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Disease Models, Animal; Echinoc | 1990 |
Experimental animal models for studying antimicrobial pharmacokinetics in otitis media.
Topics: Amoxicillin; Animals; Anti-Infective Agents; Chinchilla; Disease Models, Animal; Ear, Middle; Eustac | 1989 |
Sources of rats free of latent Pneumocystis carinii.
Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Immunosuppression Therapy; Pneumonia, Pn | 1987 |
Studies on experimentally induced hyperphenylalaninemia.
Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Fenclonine; Phenylalanine; Phenylalanine | 1988 |
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Dapsone; Diminazene; Disease Models, Animal; Drug Com | 1988 |
Effect of hyperbaric oxygenation, combined with antimicrobial agents and surgery, in a rat model of intraabdominal infection.
Topics: Abdomen; Abscess; Animals; Anti-Bacterial Agents; Bacteroides fragilis; Bacteroides Infections; Dise | 1988 |
Enhanced immune responses in mice treated with penicillin-tetracycline or trimethoprim-sulfamethoxazole when colonized intragastrically with Candida albicans.
Topics: Animals; Antibodies, Fungal; Candida albicans; Candidiasis; Disease Models, Animal; Drug Combination | 1987 |
Pentamidine aerosol in prophylaxis and treatment of murine Pneumocystis carinii pneumonia.
Topics: Aerosols; Amidines; Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Disease Mo | 1987 |
Norfloxacin versus trimethoprim-sulphamethoxazole: efficacy in a model of ascending urinary tract infection in normal and streptozotocin-induced diabetic mice.
Topics: Animals; Anti-Infective Agents; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Combin | 1985 |
Murine model for therapy of listeriosis in the compromised host. IV. Cotrimoxazole.
Topics: Ampicillin; Animals; Anti-Infective Agents, Urinary; Disease Models, Animal; Drug Combinations; Fema | 1985 |
[Comparative study on the effect of some clinically used sulfanilamide derivatives against toxoplasmosis in the mouse].
Topics: Aminobenzoates; Animals; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syn | 1973 |
[Models of urinary infection].
Topics: Animals; Bacterial Infections; Bacteriuria; Carbenicillin; Disease Models, Animal; Drug Therapy, Com | 1974 |
Mitigation of experimental inflammatory bowel disease in guinea pigs by selective elimination of the aerobic gram-negative intestinal microflora.
Topics: Animals; Bacteria; Body Weight; Carrageenan; Cecum; Colitis, Ulcerative; Colon; Disease Models, Anim | 1974 |
[Treatment of brucellosis associated with corynebacterium parvum infection in mice with antibiotics (tetracycline, ampicillin, trimethoprim-sulfamethoxazole)].
Topics: Ampicillin; Animals; Brucellosis; Cell Count; Complement Fixation Tests; Corynebacterium Infections; | 1972 |
Rat pyelonephritis model suitable for primary or secondary screening.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Disease Models, Animal; Escherich | 1969 |
Rhinophycomycosis entomophthorae occurring in a chimpanzee in the wild in East Africa.
Topics: Africa, Eastern; Animals; Disease Models, Animal; Female; Fungi; Mycoses; Nose; Nose Diseases; Pan t | 1972 |