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sulfamethoxazole and Disease Models, Animal

sulfamethoxazole has been researched along with Disease Models, Animal in 43 studies

Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"The prophylactic effect of in-feed medication of conventional pigs with sulphadimethoxine (SDM), sulphamethoxazole (SMX), and trimethoprim (TMP) was tested by using an Actinobacillus pleuropneumoniae infection model."7.70Prevention of pleuropneumonia in pigs by in-feed medication with sulphadimethoxine and sulphamethoxazole in combination with trimethoprim. ( Kuiper, HA; Mengelers, MJ; Pijpers, A; van Miert, AS; Verheijden, JH, 2000)
"Co-trimazine, a new combination of trimethoprim and sulphadiazine intended for treatment of urinary tract infections, was tested and compared to co-trimoxazole in an experimental model of acute, obstructive pyelonephritis in the rat."7.66Efficacy of two trimethoprim-sulphonamide combinations in experimental pyelonephritis in the rat. ( Ritzerfeld, W, 1979)
" Adult wild-type (WT) and Cxcr2-/- mice were fed a diet supplemented with sulfamethoxazole/trimethoprim (SMZ/TMP) during pregnancy and lactation, and their pups were injected intraperitoneally with rhesus rotavirus (RRV) within 24 hours of life to induce experimental biliary atresia."3.85Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia. ( Bezerra, JA; Fei, L; Jee, J; Mourya, R; Shivakumar, P; Wagner, M, 2017)
"The prophylactic effect of in-feed medication of conventional pigs with sulphadimethoxine (SDM), sulphamethoxazole (SMX), and trimethoprim (TMP) was tested by using an Actinobacillus pleuropneumoniae infection model."3.70Prevention of pleuropneumonia in pigs by in-feed medication with sulphadimethoxine and sulphamethoxazole in combination with trimethoprim. ( Kuiper, HA; Mengelers, MJ; Pijpers, A; van Miert, AS; Verheijden, JH, 2000)
"Co-trimazine, a new combination of trimethoprim and sulphadiazine intended for treatment of urinary tract infections, was tested and compared to co-trimoxazole in an experimental model of acute, obstructive pyelonephritis in the rat."3.66Efficacy of two trimethoprim-sulphonamide combinations in experimental pyelonephritis in the rat. ( Ritzerfeld, W, 1979)
"The results of the treatment of chronic bacterial prostatitis are disappointing."2.36Chronic bacterial prostatitis: theoretical and experimental considerations. ( Iversen, P; Jensen, KM; Madsen, PO, 1983)
" Testing of biological activity revealed limited potential for resistance to these agents, low toxicity, and highly effective in vivo activity, even with low dosing regimens."1.40Antibacterial activity of a series of N2,N4-disubstituted quinazoline-2,4-diamines. ( Burda, WN; Fleeman, R; Manetsch, R; Shaw, LN; Van Horn, KS, 2014)
"Thirty-four privately owned sulphonamide HS dogs, 10 sulphonamide-'tolerant' dogs, 18 sulphonamide-naïve dogs, and four dogs experimentally dosed with SMX and the oxidative metabolite SMX-nitroso, were tested for drug-serum adducts by immunoblotting, and anti-drug antibodies by ELISA."1.33Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity. ( Danhof, RS; Lavergne, SN; Trepanier, LA; Volkman, EM, 2006)
" Extending these experiments, we have now shown that roxithromycin at doses of 400 or 200 mg/kg/day combined with dapsone at doses of 5, 25 or 50 mg/kg/day completely prevented the development of T."1.30Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model. ( Brun-Pascaud, M; Chau, F; Derouin, F; Girard, PM, 1998)
" In the chronic cystogenic murine models, the combination TMP plus SMX administered from day 5 for 15 days or from day 28 for 288 days, gave protection and even apparent toxoplasmal eradication ('cure') at the highest dosing (60/300 mg/kg per day)."1.30Evaluation of trimethoprim and sulphamethoxazole as monotherapy or in combination in the management of toxoplasmosis in murine models. ( Dumas, JL; Pechère, JC; Pizzolato, G, 1999)
"Trimethoprim K values were also not affected by model testing sequence (p = 0/760), but were by model type (p = 0."1.29Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics. ( Canafax, DM; Erdmann, GR; Giebink, GS; Le, CT; Lovdahl, MJ; Russlie, H, 1994)
" Ro 11-8958, TMP, and diaveridine used at a dosage of 20 mg/kg/day with SMX were only slightly more effective than SMX used alone."1.29Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis. ( Foy, J; Steele, P; Walzer, PD; White, M, 1993)
"Pneumocystis carinii pneumonia is a major cause of death in AIDS patients in the United States."1.28Treatment of Pneumocystis carinii pneumonia with 1,3-beta-glucan synthesis inhibitors. ( Fromtling, RA; Nollstadt, KH; Pittarelli, LA; Romancheck, MA; Schmatz, DM; Schwartz, RE; Turner, MJ; Vanmiddlesworth, FL; Wilson, KE, 1990)
"Antimicrobial treatment of otitis media, especially drug dosing considerations, is largely empiric, with few reported pharmacologic studies of drug distribution into the middle ear."1.28Experimental animal models for studying antimicrobial pharmacokinetics in otitis media. ( Canafax, DM; Erdmann, GR; Giebink, GS; Juhn, SK; Le, CT; Nonomura, N, 1989)
"The purpose of this study was to identify new drugs for the prevention and treatment of Pneumocystis carinii pneumonitis (PCP) induced in rats by continuous daily dosage with dexamethasone."1.27Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis. ( Hughes, WT; Smith, BL, 1984)
"Suramin and dapsone were weakly active."1.27Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia. ( Clarkson, AB; Rosenberg, C; Williams, DE, 1988)
"Pentamidine was administered three times weekly via a Bird micronebulizer."1.27Pentamidine aerosol in prophylaxis and treatment of murine Pneumocystis carinii pneumonia. ( Brun-Pascaud, M; Farinotti, R; Girard, PM; Kernbaum, S; Tamisier, L, 1987)
"Norfloxacin was substantially more effective than trimethoprim-sulphamethoxazole in reducing the number of colony forming units from kidney homogenates when the test animals were diabetic."1.27Norfloxacin versus trimethoprim-sulphamethoxazole: efficacy in a model of ascending urinary tract infection in normal and streptozotocin-induced diabetic mice. ( Abruzzo, GK; Fromtling, RA; Gadebusch, HH; Gilfillan, EC; Pelak, BA, 1985)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199021 (48.84)18.7374
1990's9 (20.93)18.2507
2000's4 (9.30)29.6817
2010's6 (13.95)24.3611
2020's3 (6.98)2.80

Authors

AuthorsStudies
Van Horn, KS1
Burda, WN1
Fleeman, R1
Shaw, LN1
Manetsch, R1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Ang, CW1
Lee, BM1
Jackson, CJ1
Wang, Y3
Franzblau, SG1
Francisco, AF1
Kelly, JM1
Bernhardt, PV1
Tan, L1
West, NP1
Sykes, ML1
Hinton, AO1
Bolisetti, R1
Avery, VM1
Cooper, MA1
Blaskovich, MAT1
Karpińska, G1
Dobrowolski, JC1
Yinda, CK1
Rector, A1
Zeller, M1
Conceição-Neto, N1
Heylen, E1
Maes, P1
Ghogomu, SM1
Van Ranst, M1
Matthijnssens, J1
Arthanari, SK1
Vanitha, J1
Ganesh, M1
Venkateshwaran, K1
de Lama Caro-Patón, G1
García-Salido, A1
Iglesias-Bouzas, MI1
Guillén, M1
Cañedo-Villaroya, E1
Martínez-Romera, I1
Serrano-González, A1
Casado-Flores, J1
Gale, P2
Chen, X2
Li, H1
Lucero-Prisno, DE1
Abdullah, AS1
Huang, J1
Laurence, C1
Liang, X1
Ma, Z1
Mao, Z1
Ren, R1
Wu, S1
Wang, N1
Wang, P2
Wang, T1
Yan, H1
Zou, Y1
Olsen, KM1
Gabler, NK1
Rademacher, CJ1
Schwartz, KJ1
Schweer, WP1
Gourley, GG1
Patience, JF1
Rauch, JC1
Stokes, RS1
Shike, DW1
Luebbe, KM1
Stalker, LA1
Klopfenstein, TJ1
Funston, RN1
Unger, PA1
Lighaam, LC1
Vermeulen, E1
Kruithof, S1
Makuch, M1
Culver, EL1
van Bruggen, R1
Remmerswaal, EBM1
Ten Berge, IJM1
Emmens, RW1
Niessen, HWM1
Barnes, E1
Wolbink, GJ1
van Ham, SM1
Rispens, T1
Liang, JX1
Lin, J1
Liu, J1
Wang, X1
Zhang, T1
Li, J1
Wu, Y2
Venier, M1
Salamova, A1
Gonçales, VR1
Lian, J1
Gautam, S1
Tilley, RD1
Gooding, JJ1
Kandel, YR1
Bradley, CA1
Chilvers, MI1
Mathew, FM1
Tenuta, AU1
Smith, DL1
Wise, KA1
Mueller, DS1
Lu, N1
Lu, M1
Liu, P1
Xu, H1
Qiu, X1
Hu, S1
Bai, S1
Wu, J1
Xue, S1
Dai, X1
Dharmage, SC1
Abramson, MJ1
Erbas, B1
Bennett, CM1
Svanes, C1
Hui, J1
Axelrad, C1
Lowe, AJ1
Lodge, CJ1
Hoshi, M1
Osawa, Y1
Nakamoto, K1
Morita, N1
Yamamoto, Y1
Ando, T1
Tashita, C1
Nabeshima, T1
Saito, K1
Gianesello, L1
Del Prete, D1
Ceol, M1
Priante, G1
Calò, LA1
Anglani, F1
Vekaria, HJ1
Hubbard, WB1
Scholpa, NE1
Spry, ML1
Gooch, JL1
Prince, SJ1
Schnellmann, RG1
Sullivan, PG1
Zhang, Q1
Hu, R1
Gu, Z1
Zhang, M1
Zhang, Z1
Peng, Y1
Feng, L1
Li, X4
Zhao, C1
Sarfaraz, K1
Gao, L1
Wang, H1
Wan, C1
Leng, J1
Yang, P1
Gao, X1
Gao, J1
Emam, HE1
Saad, NM1
Abdallah, AEM1
Ahmed, HB1
Palombo, M1
Ianus, A1
Guerreri, M1
Nunes, D1
Alexander, DC1
Shemesh, N1
Zhang, H1
Xiong, Q1
Liu, YS1
Hu, LX1
Shi, ZQ1
Ying, GG1
Chen, R1
Hong, X1
Yan, S1
Zha, J1
Gu, H1
Zhong, Q1
Zeng, Y1
Zhang, S1
Bu, Y1
Farghali, M1
Mayumi, M1
Syo, K1
Satoshi, A1
Seiichi, Y1
Takashima, S1
Ono, H1
Ap, Y1
Yamashiro, T1
Ahmed, MM1
Kotb, S1
Iwasaki, M1
Ihara, I1
Umetsu, K1
Hu, B1
Quan, J1
Huang, K1
Gu, X1
Zhu, J1
Yan, Y1
Wu, P1
Yang, L1
Zhao, J1
Koók, L1
Nemestóthy, N1
Bélafi-Bakó, K1
Bakonyi, P1
Luo, X1
Zhang, F1
Li, Q1
Xia, Q1
Li, Z1
Ye, W1
Li, S1
Ge, C1
Zakkula, A1
Pulipati, S1
Dittakavi, S1
Bestha, RM1
Zainuddin, M1
Trivedi, RK1
Mullangi, R1
Lo, GH1
Lin, CW1
Tai, CM1
Perng, DS1
Chen, IL1
Yeh, JH1
Lin, HC1
Rocha, GS1
Silva, MKL1
Cesarino, I1
Hazzaa, SM1
Abdelaziz, SAM1
Abd Eldaim, MA1
Abdel-Daim, MM1
Elgarawany, GE1
Larsson, P1
Ljuslinder, I1
Öhlund, D1
Myte, R1
Löfgren-Burström, A1
Zingmark, C1
Ling, A1
Edin, S1
Palmqvist, R1
Murthi, P1
Rajaraman, G1
Erwich, JJHM1
Dimitriadis, E1
Yoon, HG1
Oh, D1
Ahn, YC1
Noh, JM1
Pyo, H1
Cho, WK1
Song, YM1
Park, M1
Hwang, NY1
Sun, JM1
Kim, HK1
Zo, JI1
Shim, YM1
Persano, A1
Quaranta, F1
Taurino, A1
Siciliano, PA1
Iannacci, J1
Malekbala, MR1
Soltani, S1
Abdul Rashid, S1
Abdullah, LC1
Rashid, U1
Nehdi, IA1
Choong, TSY1
Teo, SH1
Xu, P1
Yan, F1
Zhao, Y1
Sun, S1
Ying, L1
Quinzi, V1
Caruso, S1
Mummolo, S1
Nota, A1
Angelone, AM1
Mattei, A1
Gatto, R1
Marzo, G1
Xin, W1
Severino, J1
Venkert, A1
Yu, H1
Knorr, D1
Yang, JM1
Carlson, L1
Hicks, R1
De Rosa, I1
Beckmann, NA1
Bitsch, RG1
Schonhoff, M1
Siebenrock, KA1
Schwarze, M1
Jaeger, S1
Jee, J1
Mourya, R1
Shivakumar, P1
Fei, L1
Wagner, M1
Bezerra, JA1
Eldesouky, HE1
Abutaleb, NS1
Mohammad, H1
Seleem, MN1
Simon, V1
K V, S1
Sasikumar, R1
Kanthlal, SK1
Belal, US2
Norose, K2
Mohamed, RM2
Sekine, S1
Nukaga, T1
Ito, K1
Abdellatif, MZ1
Abdelgelil, NH1
Yano, A2
Bougie, DW1
Nayak, D1
Boylan, B1
Newman, PJ1
Aster, RH1
Aosai, F1
Mun, HS1
Ahmed, AK1
Chen, M1
Piao, LX1
Iwakura, Y1
Lavergne, SN1
Danhof, RS1
Volkman, EM1
Trepanier, LA1
Hughes, WT2
Smith, BL1
Madsen, PO1
Jensen, KM1
Iversen, P1
Killmar, JT1
Oz, HS1
Alder, J1
Hutch, T1
Meulbroek, JA1
Clement, JC1
Canafax, DM2
Russlie, H1
Lovdahl, MJ1
Erdmann, GR2
Le, CT2
Giebink, GS2
Shanks, GD1
Edstein, MD1
Chedester, AL1
Smith, CD1
Corcoran, KD1
Ngampochjana, M1
Hansukjariya, P1
Sattabongkot, J1
Webster, HK1
Walzer, PD1
Foy, J1
Steele, P1
White, M1
Yeo, AE1
Brun-Pascaud, M2
Chau, F1
Derouin, F1
Girard, PM2
Dumas, JL1
Pizzolato, G1
Pechère, JC1
Mengelers, MJ1
Kuiper, HA1
Pijpers, A1
Verheijden, JH1
van Miert, AS1
Choquet-Kastylevsky, G1
Santolaria, N1
Tedone, R1
Aujoulat, M1
Descotes, J1
Dhondt, JL2
Farriaux, JP2
Dautrevaux, M1
Biserte, G1
Hamilton-Miller, JM1
Ritzerfeld, W2
Schmatz, DM1
Romancheck, MA1
Pittarelli, LA1
Schwartz, RE1
Fromtling, RA2
Nollstadt, KH1
Vanmiddlesworth, FL1
Wilson, KE1
Turner, MJ1
Nonomura, N1
Juhn, SK1
Bartlett, MS1
Durkin, MM1
Jay, MA1
Queener, SF1
Smith, JW1
Pueschel, SM1
Boylan, J1
Ellenbogen, R1
Clarkson, AB1
Williams, DE1
Rosenberg, C1
Muhvich, KH1
Myers, RA1
Marzella, L1
Domer, JE1
Hector, RF1
Farinotti, R1
Tamisier, L1
Kernbaum, S1
Abruzzo, GK1
Gilfillan, EC1
Pelak, BA1
Gadebusch, HH1
Kawaler, B1
Hof, H1
Vischer, WA1
Prát, V1
Hatala, M1
Konícková, L1
Van der Waaij, D1
Cohen, BJ1
Anver, MR1
Philippon, A1
Kazmierczak, A1
Névot, P1
Burrous, SE1
Cawein, JB1
Roy, AD1
Cameron, HM1

Reviews

3 reviews available for sulfamethoxazole and Disease Models, Animal

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
Chronic bacterial prostatitis: theoretical and experimental considerations.
    Urological research, 1983, Volume: 11, Issue:1

    Topics: Animals; Antibody Formation; Antibody-Coated Bacteria Test, Urinary; Bacterial Infections; Chronic D

1983
Antimicrobial agents acting against anaerobes.
    The Journal of antimicrobial chemotherapy, 1975, Volume: 1, Issue:3

    Topics: Aminoglycosides; Anaerobiosis; Animals; Anti-Bacterial Agents; Bacteria; Chloramphenicol; Clindamyci

1975

Trials

1 trial available for sulfamethoxazole and Disease Models, Animal

ArticleYear
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013
    Computational & theoretical chemistry, 2013, Feb-01, Volume: 1005

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am

2013

Other Studies

40 other studies available for sulfamethoxazole and Disease Models, Animal

ArticleYear
Antibacterial activity of a series of N2,N4-disubstituted quinazoline-2,4-diamines.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Diamines; Disease Models, Animal; Hemolysis; Humans; Larva; Microbia

2014
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Nitroimidazopyrazinones with Oral Activity against Tuberculosis and Chagas Disease in Mouse Models of Infection.
    Journal of medicinal chemistry, 2022, 10-13, Volume: 65, Issue:19

    Topics: Animals; Chagas Disease; Disease Models, Animal; Mice; Mycobacterium tuberculosis; Nitroimidazoles;

2022
Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Animals; Bile Ducts; Biliary Atresia; Disease Models, Animal; Female; Gene Expression Profiling; Inf

2017
Synergistic interactions of sulfamethoxazole and azole antifungal drugs against emerging multidrug-resistant Candida auris.
    International journal of antimicrobial agents, 2018, Volume: 52, Issue:6

    Topics: Animals; Antifungal Agents; Caenorhabditis elegans; Candida; Candidiasis; Disease Models, Animal; Dr

2018
In Vitro Protective Effect of Ascorbic Acid Against Antibiotic-Induced Hepatotoxicity.
    Current drug discovery technologies, 2020, Volume: 17, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cell Survival; Chemical and Drug Induce

2020
Quantitative assessment of the effects of sulfamethoxazole on Toxoplasma gondii loads in susceptible WT C57BL/6 mice as an immunocompetent host model.
    Parasitology international, 2016, Volume: 65, Issue:1

    Topics: Animals; Brain; Coccidiostats; Disease Models, Animal; DNA, Protozoan; Heart; Immunocompetence; Lung

2016
Drug-dependent clearance of human platelets in the NOD/scid mouse by antibodies from patients with drug-induced immune thrombocytopenia.
    Blood, 2010, Oct-21, Volume: 116, Issue:16

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Antibodies; Antibodies, Monoclonal; Blood

2010
Evaluation of the effects of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-gamma knockout mice using QC-PCR.
    Microbiology and immunology, 2004, Volume: 48, Issue:3

    Topics: Animals; Disease Models, Animal; Interferon-gamma; Mice; Mice, Inbred BALB C; Mice, Knockout; Revers

2004
Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:7

    Topics: Animals; Anti-Infective Agents; Antibody Specificity; Blood Proteins; Cross Reactions; Disease Model

2006
Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:4

    Topics: Animals; Dapsone; Disease Models, Animal; Drug Combinations; Male; Pneumonia, Pneumocystis; Rats; Ra

1984
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:4

    Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Tria

1994
Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine.
    Journal of acquired immune deficiency syndromes, 1994, Volume: 7, Issue:11

    Topics: AIDS-Related Opportunistic Infections; Animals; Clarithromycin; Disease Models, Animal; Dose-Respons

1994
Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics.
    Pharmaceutical research, 1994, Volume: 11, Issue:6

    Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Chinchilla; Diffusion; Disease Models, Animal; Ear, Mid

1994
Proguanil plus sulfamethoxazole is not causally prophylactic in the Macaca mulatta--Plasmodium cynomolgi model.
    The American journal of tropical medicine and hygiene, 1994, Volume: 50, Issue:5

    Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Liver; Macaca mulatta; Malaria; Male; Pl

1994
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Animals; Dapsone; Disease Models, Animal; Dose-Response Relat

1993
Direct comparison of antimalarial activity among PS-15 combination therapies by bioassay of serum samples from treated Saimiri sciureus.
    The Journal of parasitology, 1997, Volume: 83, Issue:3

    Topics: Animals; Antimalarials; Atovaquone; Biological Assay; Dapsone; Disease Models, Animal; Drug Synergis

1997
Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41 Suppl B

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Disease Models, Animal; Dose-Respons

1998
Evaluation of trimethoprim and sulphamethoxazole as monotherapy or in combination in the management of toxoplasmosis in murine models.
    International journal of antimicrobial agents, 1999, Volume: 13, Issue:1

    Topics: Animals; Chronic Disease; Disease Models, Animal; Drug Evaluation; Mice; Sulfamethoxazole; Toxoplasm

1999
Prevention of pleuropneumonia in pigs by in-feed medication with sulphadimethoxine and sulphamethoxazole in combination with trimethoprim.
    The veterinary quarterly, 2000, Volume: 22, Issue:3

    Topics: Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animal Feed; Animals; Anti-Bacterial Age

2000
Induction of delayed-type hypersensitivity to sulfamethoxazole in mice: role of metabolites.
    Toxicology letters, 2001, Mar-08, Volume: 119, Issue:3

    Topics: Animals; Anti-Infective Agents; CD4 Lymphocyte Count; Disease Models, Animal; Drug Hypersensitivity;

2001
Study of blood aminoacids in experimental hyperphenylalaninemia.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:2

    Topics: Amino Acids; Animals; Disease Models, Animal; Fenclonine; Humans; Male; Phenylalanine; Phenylketonur

1977
A new experimental model of hyperphenylalaninemia in rat. Effect of p-chlorophenylalanine and cotrimoxazole.
    Biochimie, 1977, Volume: 59, Issue:8-9

    Topics: Animals; Disease Models, Animal; Drug Combinations; Fenclonine; Humans; Kidney; Liver; Male; Phenyla

1977
Efficacy of two trimethoprim-sulphonamide combinations in experimental pyelonephritis in the rat.
    Infection, 1979, Volume: 7 Suppl 4

    Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Escherichia coli I

1979
Treatment of Pneumocystis carinii pneumonia with 1,3-beta-glucan synthesis inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:15

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Disease Models, Animal; Echinoc

1990
Experimental animal models for studying antimicrobial pharmacokinetics in otitis media.
    Pharmaceutical research, 1989, Volume: 6, Issue:4

    Topics: Amoxicillin; Animals; Anti-Infective Agents; Chinchilla; Disease Models, Animal; Ear, Middle; Eustac

1989
Sources of rats free of latent Pneumocystis carinii.
    Journal of clinical microbiology, 1987, Volume: 25, Issue:9

    Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Immunosuppression Therapy; Pneumonia, Pn

1987
Studies on experimentally induced hyperphenylalaninemia.
    Journal of mental deficiency research, 1988, Volume: 32 ( Pt 4)

    Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Fenclonine; Phenylalanine; Phenylalanine

1988
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8

    Topics: Amphotericin B; Animals; Antiprotozoal Agents; Dapsone; Diminazene; Disease Models, Animal; Drug Com

1988
Effect of hyperbaric oxygenation, combined with antimicrobial agents and surgery, in a rat model of intraabdominal infection.
    The Journal of infectious diseases, 1988, Volume: 157, Issue:5

    Topics: Abdomen; Abscess; Animals; Anti-Bacterial Agents; Bacteroides fragilis; Bacteroides Infections; Dise

1988
Enhanced immune responses in mice treated with penicillin-tetracycline or trimethoprim-sulfamethoxazole when colonized intragastrically with Candida albicans.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:5

    Topics: Animals; Antibodies, Fungal; Candida albicans; Candidiasis; Disease Models, Animal; Drug Combination

1987
Pentamidine aerosol in prophylaxis and treatment of murine Pneumocystis carinii pneumonia.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:7

    Topics: Aerosols; Amidines; Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Disease Mo

1987
Norfloxacin versus trimethoprim-sulphamethoxazole: efficacy in a model of ascending urinary tract infection in normal and streptozotocin-induced diabetic mice.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:6

    Topics: Animals; Anti-Infective Agents; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Combin

1985
Murine model for therapy of listeriosis in the compromised host. IV. Cotrimoxazole.
    Chemotherapy, 1985, Volume: 31, Issue:5

    Topics: Ampicillin; Animals; Anti-Infective Agents, Urinary; Disease Models, Animal; Drug Combinations; Fema

1985
[Comparative study on the effect of some clinically used sulfanilamide derivatives against toxoplasmosis in the mouse].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1973, Volume: 223, Issue:2

    Topics: Aminobenzoates; Animals; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syn

1973
[Models of urinary infection].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1974, Volume: 227, Issue:1-4

    Topics: Animals; Bacterial Infections; Bacteriuria; Carbenicillin; Disease Models, Animal; Drug Therapy, Com

1974
Mitigation of experimental inflammatory bowel disease in guinea pigs by selective elimination of the aerobic gram-negative intestinal microflora.
    Gastroenterology, 1974, Volume: 67, Issue:3

    Topics: Animals; Bacteria; Body Weight; Carrageenan; Cecum; Colitis, Ulcerative; Colon; Disease Models, Anim

1974
[Treatment of brucellosis associated with corynebacterium parvum infection in mice with antibiotics (tetracycline, ampicillin, trimethoprim-sulfamethoxazole)].
    Annales de l'Institut Pasteur, 1972, Volume: 123, Issue:3

    Topics: Ampicillin; Animals; Brucellosis; Cell Count; Complement Fixation Tests; Corynebacterium Infections;

1972
Rat pyelonephritis model suitable for primary or secondary screening.
    Applied microbiology, 1969, Volume: 18, Issue:3

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Disease Models, Animal; Escherich

1969
Rhinophycomycosis entomophthorae occurring in a chimpanzee in the wild in East Africa.
    The American journal of tropical medicine and hygiene, 1972, Volume: 21, Issue:2

    Topics: Africa, Eastern; Animals; Disease Models, Animal; Female; Fungi; Mycoses; Nose; Nose Diseases; Pan t

1972