sulfamethoxazole has been researched along with Chemical and Drug Induced Liver Injury in 36 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with several episodes of jaundice associated with sulfamethoxazole therapy is described." | 3.66 | Sulfamethoxazole-induced hepatic injury. ( Mishkin, S; Steinbrecher, UP, 1981) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "During the decade 1968-1978 the Danish Board of Adverse Reactions to Drugs received 572 (6% of the total number) reports on hepatotoxicity." | 1.26 | Drug-induced liver disease in Denmark. An analysis of 572 cases of hepatotoxicity reported to the Danish Board of Adverse Reactions to Drugs. ( Andreasen, PB; Døssing, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (72.22) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (19.44) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 1 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Karpińska, G | 1 |
| Dobrowolski, JC | 1 |
| Yinda, CK | 1 |
| Rector, A | 1 |
| Zeller, M | 1 |
| Conceição-Neto, N | 1 |
| Heylen, E | 1 |
| Maes, P | 1 |
| Ghogomu, SM | 1 |
| Van Ranst, M | 1 |
| Matthijnssens, J | 1 |
| Arthanari, SK | 1 |
| Vanitha, J | 1 |
| Ganesh, M | 1 |
| Venkateshwaran, K | 1 |
| de Lama Caro-Patón, G | 1 |
| García-Salido, A | 1 |
| Iglesias-Bouzas, MI | 1 |
| Guillén, M | 1 |
| Cañedo-Villaroya, E | 1 |
| Martínez-Romera, I | 1 |
| Serrano-González, A | 1 |
| Casado-Flores, J | 1 |
| Gale, P | 2 |
| Chen, X | 2 |
| Li, H | 1 |
| Lucero-Prisno, DE | 1 |
| Abdullah, AS | 1 |
| Huang, J | 1 |
| Laurence, C | 1 |
| Liang, X | 1 |
| Ma, Z | 1 |
| Mao, Z | 1 |
| Ren, R | 1 |
| Wu, S | 1 |
| Wang, N | 1 |
| Wang, P | 2 |
| Wang, T | 1 |
| Yan, H | 1 |
| Zou, Y | 1 |
| Olsen, KM | 1 |
| Gabler, NK | 1 |
| Rademacher, CJ | 1 |
| Schwartz, KJ | 1 |
| Schweer, WP | 1 |
| Gourley, GG | 1 |
| Patience, JF | 1 |
| Rauch, JC | 1 |
| Stokes, RS | 1 |
| Shike, DW | 1 |
| Luebbe, KM | 1 |
| Stalker, LA | 1 |
| Klopfenstein, TJ | 1 |
| Funston, RN | 1 |
| Unger, PA | 1 |
| Lighaam, LC | 1 |
| Vermeulen, E | 1 |
| Kruithof, S | 1 |
| Makuch, M | 1 |
| Culver, EL | 1 |
| van Bruggen, R | 1 |
| Remmerswaal, EBM | 1 |
| Ten Berge, IJM | 1 |
| Emmens, RW | 1 |
| Niessen, HWM | 1 |
| Barnes, E | 1 |
| Wolbink, GJ | 1 |
| van Ham, SM | 1 |
| Rispens, T | 1 |
| Liang, JX | 1 |
| Lin, J | 1 |
| Liu, J | 1 |
| Wang, X | 1 |
| Zhang, T | 1 |
| Li, J | 1 |
| Wu, Y | 2 |
| Venier, M | 1 |
| Salamova, A | 1 |
| Gonçales, VR | 1 |
| Lian, J | 1 |
| Gautam, S | 1 |
| Tilley, RD | 1 |
| Gooding, JJ | 1 |
| Kandel, YR | 1 |
| Bradley, CA | 1 |
| Chilvers, MI | 1 |
| Mathew, FM | 1 |
| Tenuta, AU | 1 |
| Smith, DL | 1 |
| Wise, KA | 1 |
| Mueller, DS | 1 |
| Lu, N | 1 |
| Lu, M | 1 |
| Liu, P | 1 |
| Xu, H | 1 |
| Qiu, X | 1 |
| Hu, S | 1 |
| Bai, S | 1 |
| Wu, J | 1 |
| Xue, S | 1 |
| Dai, X | 1 |
| Dharmage, SC | 1 |
| Abramson, MJ | 1 |
| Erbas, B | 1 |
| Bennett, CM | 1 |
| Svanes, C | 1 |
| Hui, J | 1 |
| Axelrad, C | 1 |
| Lowe, AJ | 1 |
| Lodge, CJ | 1 |
| Hoshi, M | 1 |
| Osawa, Y | 1 |
| Nakamoto, K | 1 |
| Morita, N | 1 |
| Yamamoto, Y | 1 |
| Ando, T | 1 |
| Tashita, C | 1 |
| Nabeshima, T | 1 |
| Saito, K | 1 |
| Gianesello, L | 1 |
| Del Prete, D | 1 |
| Ceol, M | 1 |
| Priante, G | 1 |
| Calò, LA | 1 |
| Anglani, F | 1 |
| Vekaria, HJ | 1 |
| Hubbard, WB | 1 |
| Scholpa, NE | 1 |
| Spry, ML | 1 |
| Gooch, JL | 1 |
| Prince, SJ | 1 |
| Schnellmann, RG | 1 |
| Sullivan, PG | 1 |
| Zhang, Q | 1 |
| Hu, R | 1 |
| Gu, Z | 1 |
| Zhang, M | 1 |
| Zhang, Z | 1 |
| Peng, Y | 1 |
| Feng, L | 1 |
| Li, X | 3 |
| Zhao, C | 1 |
| Sarfaraz, K | 1 |
| Gao, L | 1 |
| Wang, H | 1 |
| Wan, C | 1 |
| Leng, J | 1 |
| Yang, P | 1 |
| Gao, X | 1 |
| Gao, J | 1 |
| Emam, HE | 1 |
| Saad, NM | 1 |
| Abdallah, AEM | 1 |
| Ahmed, HB | 1 |
| Palombo, M | 1 |
| Ianus, A | 1 |
| Guerreri, M | 1 |
| Nunes, D | 1 |
| Alexander, DC | 1 |
| Shemesh, N | 1 |
| Zhang, H | 1 |
| Xiong, Q | 1 |
| Liu, YS | 1 |
| Hu, LX | 1 |
| Shi, ZQ | 1 |
| Ying, GG | 1 |
| Chen, R | 1 |
| Hong, X | 1 |
| Yan, S | 1 |
| Zha, J | 1 |
| Gu, H | 1 |
| Zhong, Q | 1 |
| Zeng, Y | 1 |
| Zhang, S | 1 |
| Bu, Y | 1 |
| Farghali, M | 1 |
| Mayumi, M | 1 |
| Syo, K | 1 |
| Satoshi, A | 1 |
| Seiichi, Y | 1 |
| Takashima, S | 1 |
| Ono, H | 1 |
| Ap, Y | 1 |
| Yamashiro, T | 1 |
| Ahmed, MM | 1 |
| Kotb, S | 1 |
| Iwasaki, M | 1 |
| Ihara, I | 1 |
| Umetsu, K | 1 |
| Hu, B | 1 |
| Wang, Y | 2 |
| Quan, J | 1 |
| Huang, K | 1 |
| Gu, X | 1 |
| Zhu, J | 1 |
| Yan, Y | 1 |
| Wu, P | 1 |
| Yang, L | 1 |
| Zhao, J | 1 |
| Koók, L | 1 |
| Nemestóthy, N | 1 |
| Bélafi-Bakó, K | 1 |
| Bakonyi, P | 1 |
| Luo, X | 1 |
| Zhang, F | 1 |
| Li, Q | 1 |
| Xia, Q | 1 |
| Li, Z | 1 |
| Ye, W | 1 |
| Li, S | 1 |
| Ge, C | 1 |
| Zakkula, A | 1 |
| Pulipati, S | 1 |
| Dittakavi, S | 1 |
| Bestha, RM | 1 |
| Zainuddin, M | 1 |
| Trivedi, RK | 1 |
| Mullangi, R | 1 |
| Lo, GH | 1 |
| Lin, CW | 1 |
| Tai, CM | 1 |
| Perng, DS | 1 |
| Chen, IL | 1 |
| Yeh, JH | 1 |
| Lin, HC | 1 |
| Rocha, GS | 1 |
| Silva, MKL | 1 |
| Cesarino, I | 1 |
| Hazzaa, SM | 1 |
| Abdelaziz, SAM | 1 |
| Abd Eldaim, MA | 1 |
| Abdel-Daim, MM | 1 |
| Elgarawany, GE | 1 |
| Larsson, P | 1 |
| Ljuslinder, I | 1 |
| Öhlund, D | 1 |
| Myte, R | 1 |
| Löfgren-Burström, A | 1 |
| Zingmark, C | 1 |
| Ling, A | 1 |
| Edin, S | 1 |
| Palmqvist, R | 1 |
| Murthi, P | 1 |
| Rajaraman, G | 1 |
| Erwich, JJHM | 1 |
| Dimitriadis, E | 1 |
| Yoon, HG | 1 |
| Oh, D | 1 |
| Ahn, YC | 1 |
| Noh, JM | 1 |
| Pyo, H | 1 |
| Cho, WK | 1 |
| Song, YM | 1 |
| Park, M | 1 |
| Hwang, NY | 1 |
| Sun, JM | 1 |
| Kim, HK | 1 |
| Zo, JI | 1 |
| Shim, YM | 1 |
| Persano, A | 1 |
| Quaranta, F | 1 |
| Taurino, A | 1 |
| Siciliano, PA | 1 |
| Iannacci, J | 1 |
| Malekbala, MR | 1 |
| Soltani, S | 1 |
| Abdul Rashid, S | 1 |
| Abdullah, LC | 1 |
| Rashid, U | 1 |
| Nehdi, IA | 1 |
| Choong, TSY | 1 |
| Teo, SH | 1 |
| Xu, P | 1 |
| Yan, F | 1 |
| Zhao, Y | 1 |
| Sun, S | 1 |
| Ying, L | 1 |
| Quinzi, V | 1 |
| Caruso, S | 1 |
| Mummolo, S | 1 |
| Nota, A | 1 |
| Angelone, AM | 1 |
| Mattei, A | 1 |
| Gatto, R | 1 |
| Marzo, G | 1 |
| Xin, W | 1 |
| Severino, J | 1 |
| Venkert, A | 1 |
| Yu, H | 1 |
| Knorr, D | 1 |
| Yang, JM | 1 |
| Carlson, L | 1 |
| Hicks, R | 1 |
| De Rosa, I | 1 |
| Beckmann, NA | 1 |
| Bitsch, RG | 1 |
| Schonhoff, M | 1 |
| Siebenrock, KA | 1 |
| Schwarze, M | 1 |
| Jaeger, S | 1 |
| Simon, V | 1 |
| K V, S | 1 |
| Sasikumar, R | 1 |
| Kanthlal, SK | 1 |
| Thies, PW | 1 |
| Dull, WL | 1 |
| Kossow, AS | 1 |
| Døssing, M | 1 |
| Andreasen, PB | 1 |
| Wist, E | 1 |
| Coto, H | 1 |
| McGowan, WR | 1 |
| Pierce, EH | 1 |
| Thomas, E | 1 |
| Steinbrecher, UP | 1 |
| Mishkin, S | 1 |
| Knudsen, L | 1 |
| Weismann, K | 1 |
| Stevenson, DK | 1 |
| Christie, DL | 1 |
| Haas, JE | 1 |
| Talbot, IC | 1 |
| Juul, P | 1 |
| Colucci, CF | 1 |
| Lo Cicero, M | 1 |
| Hermansen, K | 1 |
| Baunsgaard, P | 1 |
| Heydenreich, G | 1 |
| Nielsen, G | 1 |
| Hofer, T | 1 |
| Becker, EW | 1 |
| Weigand, K | 1 |
| Berg, PA | 2 |
| Muñoz, SJ | 1 |
| Martinez-Hernandez, A | 1 |
| Maddrey, WC | 1 |
| Pavlova, MV | 1 |
| Natov, SN | 1 |
| Badev, IR | 1 |
| Victorino, RM | 1 |
| Maria, VA | 1 |
| Karim, AH | 1 |
| Goldberg, J | 1 |
| Kassel, LE | 1 |
| Bhagavan, BS | 1 |
| Israel, HL | 1 |
| Daniel, PT | 1 |
| Horák, J | 1 |
| Mertl, L | 1 |
| Hrabal, P | 1 |
| Bartlett, JC | 1 |
| Park, H | 1 |
| Moe, R | 1 |
| Acero, D | 1 |
| Masabeu, A | 1 |
| Alabern, C | 1 |
| Oterino, A | 1 |
| Klein, U | 1 |
| Gikalov, I | 1 |
| Keller, M | 1 |
| Hoigné, R | 1 |
| Macoul, KL | 1 |
| Babior, BM | 1 |
| Davidson, CS | 1 |
| Tönder, M | 1 |
| Nordöy, A | 1 |
| Elgjo, K | 1 |
| Shaw, DJ | 1 |
| Jacobs, RP | 1 |
| Fries, J | 1 |
| Siragenian, R | 1 |
2 reviews available for sulfamethoxazole and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am | 2013 |
Acute liver injury.
Topics: Acetaminophen; Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hepati | 1975 |
1 trial available for sulfamethoxazole and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am | 2013 |
34 other studies available for sulfamethoxazole and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
In Vitro Protective Effect of Ascorbic Acid Against Antibiotic-Induced Hepatotoxicity.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cell Survival; Chemical and Drug Induce | 2020 |
Trimethoprim-sulfamethoxazole-induced cholestatic hepatitis. Inadvertent rechallenge.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Combinations; Humans | 1984 |
Hepatic injury complicating sulfa therapy: case report.
Topics: Aged; Chemical and Drug Induced Liver Injury; Drug Combinations; Humans; Male; Sulfamethoxazole; Tri | 1984 |
Drug-induced liver disease in Denmark. An analysis of 572 cases of hepatotoxicity reported to the Danish Board of Adverse Reactions to Drugs.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Antidepressive Agents, Tricyclic; Antituber | 1982 |
[Pathological liver function tests due to trimethoprim-sulfamethoxazole].
Topics: Aged; Anti-Infective Agents, Urinary; Chemical and Drug Induced Liver Injury; Drug Combinations; Fem | 1982 |
Intrahepatic cholestasis due to trimethoprim-sulfamethoxazole.
Topics: Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Combinations; Humans; Liver; | 1981 |
Sulfamethoxazole-induced hepatic injury.
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Female; Humans; Jaundice | 1981 |
[Pustular eruption and damage of internal organs after sulfamethoxazole combined with trimethoprim].
Topics: Aged; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug Eruptions; Humans; Kidney; Kid | 1977 |
Hepatic injury in a child caused by trimethoprim-sulfamethoxazole.
Topics: Adolescent; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Combinations; Drug Hyp | 1978 |
[Adverse effects of treatment with sulfamethoxazole and trimethoprim. Report to the Adverse Drug Reaction Committee of the National Board of Health and Welfare].
Topics: Aged; Chemical and Drug Induced Liver Injury; Denmark; Drug Combinations; Drug Hypersensitivity; Fem | 1977 |
Letter: Hepatic necrosis and trimethoprim-sulfamethoxazole.
Topics: Aged; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Necrosis; Orchitis; Sulfamethoxaz | 1975 |
[Liver changes after sulfamethoxazole-trimethoprim (Bactrim, Trisural)].
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Liver; Male; Sulfa | 1976 |
Demonstration of sensitized lymphocytes to trimethoprim/sulfamethoxazole and ofloxacin in a patient with cholestatic hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Female; Humans; O | 1992 |
Intrahepatic cholestasis and phospholipidosis associated with the use of trimethoprim-sulfamethoxazole.
Topics: Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Combinations; Female; Humans | 1990 |
[A case of drug-induced recurrent cholestatic hepatitis].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Combinations; Humans; | 1989 |
Drug-induced hepatitis and lymphocyte transformation test in presence of prostaglandin inhibitor.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Combinations; Humans; In Vitro Techniques; Lymph | 1986 |
Postantibiotic fever, jaundice, dysuria.
Topics: Aged; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Drug Combinations; Fever; Human | 1986 |
Sulfamethoxazole-trimethoprim therapy for Wegener's granulomatosis.
Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Granulom | 1988 |
Co-trimoxazole-induced hepatic injury--an analysis of cases with hypersensitivity-like reactions.
Topics: Adult; Aged; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug | 1987 |
[Acute liver failure and severe cholestasis due to sulfonamides].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Combinations; Female; Hepatic Encep | 1985 |
Hepatic toxicity associated with trimethoprim-sulfamethoxazole: report of a case.
Topics: Aged; Anti-Infective Agents, Urinary; Chemical and Drug Induced Liver Injury; Drug Combinations; Hum | 1985 |
[Cholestasis caused by co-trimoxazole. Presentation of a new patient and review of the literature].
Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Combinations; Drug Hyp | 1985 |
[Drug monitoring in the medical ward of a regional hospital].
Topics: Adult; Ampicillin; Anticoagulants; Antidepressive Agents; Central Nervous System Stimulants; Chemica | 1972 |
Hepatitis attributed to sulfamethoxazole.
Topics: Aged; Chemical and Drug Induced Liver Injury; Drug Eruptions; Humans; Male; Sulfamethoxazole; Sulfon | 1966 |
Hepatitis: drug or viral?
Topics: Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Halothane; Hepatitis A; Humans; Ipr | 1966 |
Sulfonamide-induced chronic liver disease.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Follow-Up Studies; Humans; | 1974 |
Simultaneous occurrence of toxic hepatitis and Stevens-Johnson syndrome following therapy with sulfisoxazole and sulfamethoxazole.
Topics: Adult; Biopsy; Chemical and Drug Induced Liver Injury; Eosinophilia; Erythema Multiforme; Female; Hu | 1970 |
Sulfonamide hepatitis. Report of a case due to sulfamethoxazole and sulfisoxazole.
Topics: Chemical and Drug Induced Liver Injury; Female; Humans; Middle Aged; Sulfamethoxazole; Sulfisoxazole | 1966 |