sulfamethoxazole has been researched along with Body Weight in 20 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection." | 9.04 | Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975) |
| "Trimethoprim/sulfamethoxazole (TMP/SMX) and clindamycin are frequently prescribed to treat cellulitis." | 7.85 | Clinical outcomes in patients hospitalized with cellulitis treated with oral clindamycin and trimethoprim/sulfamethoxazole: The role of weight-based dosing. ( Alexander, B; Cox, KK; Heintz, BH; Livorsi, DJ, 2017) |
| "The disposition of 12 mg of trimethoprim and 60 mg of sulfamethoxazole per kg of body weight in six healthy male volunteers is described." | 7.68 | Multiple-dose pharmacokinetics of 12 milligrams of trimethoprim and 60 milligrams of sulfamethoxazole per kilogram of body weight per day in healthy volunteers. ( Laizure, SC; Sanders, PL; Stein, DS; Stevens, RC, 1993) |
| " the half-life t1/2 of their elimination from the plasma; 4." | 5.25 | [Comparison of pharmacokinetics of the combination trimethoprim and sulfamethoxazole in patients with liver diseases and healthy persons]. ( Rieder, VJ; Schwartz, DE, 1975) |
| "Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection." | 5.04 | Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975) |
| "Trimethoprim/sulfamethoxazole (TMP/SMX) and clindamycin are frequently prescribed to treat cellulitis." | 3.85 | Clinical outcomes in patients hospitalized with cellulitis treated with oral clindamycin and trimethoprim/sulfamethoxazole: The role of weight-based dosing. ( Alexander, B; Cox, KK; Heintz, BH; Livorsi, DJ, 2017) |
| "The disposition of 12 mg of trimethoprim and 60 mg of sulfamethoxazole per kg of body weight in six healthy male volunteers is described." | 3.68 | Multiple-dose pharmacokinetics of 12 milligrams of trimethoprim and 60 milligrams of sulfamethoxazole per kilogram of body weight per day in healthy volunteers. ( Laizure, SC; Sanders, PL; Stein, DS; Stevens, RC, 1993) |
| " They were aged 2-12 years at the start of prophylaxis which was given in a daily dose of approximately 10 mg sulphamethoxazole (SMX) and 2 mg trimethoprim (TMP)/kg body weight for at least 6 months and for up to 6 years." | 3.66 | Normal somatic growth in children receiving low-dose prophylactic co-trimoxazole. ( Paton, AM; Preece, MA; Smellie, JM, 1983) |
| "Body weight was the same in all groups." | 1.28 | Ascending pyelonephritis in young rats retards kidney growth. ( Aperia, A; Celsi, G; Eklöf, AC; Hannerz, L; Olling, S; Wikstad, I, 1989) |
| "Fifteen patients with AIDS were hospitalized on the pulmonary service during the period from 1981 to 1983." | 1.27 | Pulmonary manifestations of the acquired immunodeficiency syndrome (AIDS). ( Chitkara, RK; Khan, FA; Shivaram, U; Wollschlager, CM, 1984) |
| " This value is one of important parameters in a dosage equation by the pharmacokinetics, it showing sigma in an equation, were determined by clinical trial for acute simple cystitis of women." | 1.25 | The correlation between the clinical effectiveness and ratio of blood concentration to minimum inhibitory concentration of sulfamethoxazole against Escherichia coli isolates. The determination of a parameter in a dosage equation by the pharmacokinetics. ( Kuraoka, Y; Otaya, H, 1975) |
| " the half-life t1/2 of their elimination from the plasma; 4." | 1.25 | [Comparison of pharmacokinetics of the combination trimethoprim and sulfamethoxazole in patients with liver diseases and healthy persons]. ( Rieder, VJ; Schwartz, DE, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (80.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cox, KK | 1 |
| Alexander, B | 1 |
| Livorsi, DJ | 1 |
| Heintz, BH | 1 |
| Yu, Z | 1 |
| Yin, D | 1 |
| Zhang, J | 1 |
| Smellie, JM | 2 |
| Preece, MA | 2 |
| Paton, AM | 2 |
| Wollschlager, CM | 1 |
| Khan, FA | 1 |
| Chitkara, RK | 1 |
| Shivaram, U | 1 |
| Sieniawska, M | 1 |
| Wróblewska-Kałuzewska, M | 1 |
| Białasik, D | 1 |
| Korniszewska, J | 1 |
| Wierzbowska-Lange, B | 1 |
| Wierzba, K | 1 |
| Stevens, RC | 1 |
| Laizure, SC | 1 |
| Sanders, PL | 1 |
| Stein, DS | 1 |
| Torii, M | 1 |
| Itoh, F | 1 |
| Yabuuchi, K | 1 |
| Ohno, K | 1 |
| Kominami, G | 1 |
| Hirano, K | 1 |
| Tasaki, T | 1 |
| Nara, H | 1 |
| Sabel, KG | 1 |
| Brandberg, A | 1 |
| Cameron, GG | 1 |
| Pomahac, AC | 1 |
| Johnston, MT | 1 |
| Otaya, H | 1 |
| Kuraoka, Y | 1 |
| Rieder, VJ | 1 |
| Schwartz, DE | 1 |
| Hannerz, L | 1 |
| Celsi, G | 1 |
| Eklöf, AC | 1 |
| Olling, S | 1 |
| Wikstad, I | 1 |
| Aperia, A | 1 |
| Van der Waaij, D | 1 |
| Cohen, BJ | 1 |
| Anver, MR | 1 |
| Koch-Weser, J | 1 |
| Sidel, VW | 1 |
| Dexter, M | 1 |
| Parish, C | 1 |
| Finer, DC | 1 |
| Kanarek, P | 1 |
| Pohjanpelto, PE | 1 |
| Sarmela, TJ | 1 |
| Raines, T | 1 |
| Wolfsdorf, J | 1 |
| Myer, EC | 1 |
| Swarm, RL | 1 |
| Roberts, GK | 1 |
| Levy, AC | 1 |
| Hines, LR | 1 |
| Suter, HJ | 1 |
| Guggenheim, B | 1 |
| Bach, MC | 1 |
| Gold, O | 1 |
| Finland, M | 1 |
3 trials available for sulfamethoxazole and Body Weight
| Article | Year |
|---|---|
Somatic growth in girls receiving low dose prophylactic co-trimoxazole.
Topics: Anti-Infective Agents, Urinary; Body Weight; Child; Child, Preschool; Drug Combinations; Female; Gro | 1983 |
Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media.
Topics: Administration, Oral; Ampicillin; Bacterial Infections; Body Weight; Child; Clinical Trials as Topic | 1975 |
Trimethoprim-sulphonamide mixture in the treatment of infantile gastro-enteritis.
Topics: Body Weight; Child, Preschool; Clinical Trials as Topic; Diarrhea, Infantile; Drug Combinations; Esc | 1973 |
17 other studies available for sulfamethoxazole and Body Weight
| Article | Year |
|---|---|
Clinical outcomes in patients hospitalized with cellulitis treated with oral clindamycin and trimethoprim/sulfamethoxazole: The role of weight-based dosing.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Body Weight; Cellulitis; Clindamycin; Cohort Stud | 2017 |
Sex-dependent effects of sulfamethoxazole exposure on pro-/anti-oxidant status with stimulation on growth, behavior and reproduction in the amphipod Hyalella azteca.
Topics: Acetylcholinesterase; Amphipoda; Animals; Anti-Infective Agents; Antioxidants; Body Weight; Female; | 2019 |
Normal somatic growth in children receiving low-dose prophylactic co-trimoxazole.
Topics: Body Height; Body Weight; Child; Child, Preschool; Drug Combinations; Female; Growth; Humans; Sulfam | 1983 |
Pulmonary manifestations of the acquired immunodeficiency syndrome (AIDS).
Topics: Acquired Immunodeficiency Syndrome; Adult; Body Weight; Cough; Female; Humans; Lung; Lung Diseases; | 1984 |
[Biseptol dosage in children in relation to the degree of renal failure and body weight. II].
Topics: Acute Kidney Injury; Adolescent; Body Weight; Child; Child, Preschool; Dose-Response Relationship, D | 1984 |
Multiple-dose pharmacokinetics of 12 milligrams of trimethoprim and 60 milligrams of sulfamethoxazole per kilogram of body weight per day in healthy volunteers.
Topics: Adult; Body Weight; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Male; Su | 1993 |
Twenty-six-week carcinogenicity study of sulfamethoxazole in CB6F1-Tg-rasH2 mice.
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Female; Genes, ras; Harderian Gland; Human | 2001 |
Treatment of meningitis and septicemia in infancy with a sulphamethoxazole/trimethorpim combination.
Topics: Ampicillin; Anemia, Hypochromic; Body Weight; Drug Synergism; Drug Therapy, Combination; Escherichia | 1975 |
The correlation between the clinical effectiveness and ratio of blood concentration to minimum inhibitory concentration of sulfamethoxazole against Escherichia coli isolates. The determination of a parameter in a dosage equation by the pharmacokinetics.
Topics: Adult; Body Weight; Cystitis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug R | 1975 |
[Comparison of pharmacokinetics of the combination trimethoprim and sulfamethoxazole in patients with liver diseases and healthy persons].
Topics: Adult; Aged; Body Weight; Drug Combinations; Female; Half-Life; Humans; Liver Diseases; Male; Middle | 1975 |
Ascending pyelonephritis in young rats retards kidney growth.
Topics: Aging; Animals; Body Weight; DNA; Drug Combinations; Escherichia coli Infections; Female; Glomerular | 1989 |
Mitigation of experimental inflammatory bowel disease in guinea pigs by selective elimination of the aerobic gram-negative intestinal microflora.
Topics: Animals; Bacteria; Body Weight; Carrageenan; Cecum; Colitis, Ulcerative; Colon; Disease Models, Anim | 1974 |
Adverse reactions to sulfisoxazole, sulfamethoxazole, and nitrofurantoin. Manifestations and specific reaction rates during 2,118 courses of therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Body Weight; Drug Eruptions; Eosinophilia; Female; Fever; Gast | 1971 |
Penetration of trimethoprim and sulphamethoxazole into the aqueous humour.
Topics: Administration, Oral; Animals; Aqueous Humor; Body Weight; Drug Synergism; Female; Humans; Male; Rab | 1974 |
Observations on the thyroid gland in rats following the administration of sulfamethoxazole and trimethoprim.
Topics: Animals; Anti-Infective Agents; Appetite; Behavior, Animal; Body Weight; Dose-Response Relationship, | 1973 |
The inhibitory effect of two slightly soluble compounds on rat caries.
Topics: Administration, Topical; Animals; Body Weight; Cariostatic Agents; Dental Caries; Diet, Cariogenic; | 1972 |
Absorption and urinary execretion of trimethoprim, sulfamethoxazole, and trimethoprim-sulfamethoxazole: results with single doses in normal young adults and preliminary observations during therapy with trimethoprim-sulfamethoxazole.
Topics: Administration, Oral; Body Weight; Drug Combinations; Erythrocytes; Female; Humans; Male; Sulfametho | 1973 |