sulfamethoxazole has been researched along with Bile Duct Obstruction in 9 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 52-year old woman developed severe cholestasis seven days after the administration of trimethoprim-sulfamethoxazole (RMP-SMZ) The clinical and pathologic features are discussed as well as the various mechanisms of liver injury following TMP-SMZ use." | 7.66 | Trimethoprim-sulfamethoxazole-induced cholestasis. ( Abi-Mansur, P; Allam, C; Ardiaca, MC; Shamma'a, M, 1981) |
| "A patient with several episodes of jaundice associated with sulfamethoxazole therapy is described." | 3.66 | Sulfamethoxazole-induced hepatic injury. ( Mishkin, S; Steinbrecher, UP, 1981) |
| "A 52-year old woman developed severe cholestasis seven days after the administration of trimethoprim-sulfamethoxazole (RMP-SMZ) The clinical and pathologic features are discussed as well as the various mechanisms of liver injury following TMP-SMZ use." | 3.66 | Trimethoprim-sulfamethoxazole-induced cholestasis. ( Abi-Mansur, P; Allam, C; Ardiaca, MC; Shamma'a, M, 1981) |
| " The method was validated and applied to compare the pharmacokinetic profiles of the analytes in serum of Alpha-naphthylisothiocyanate (ANIT)-induced cholestasis and control rats after oral administration of XYLDF." | 1.62 | Pharmacokinetic study of seven bioactive components of Xiaoyan Lidan Formula in cholestatic and control rats using UPLC-MS/MS. ( Huang, T; Lin, C; Liu, F; Wang, M; Yao, Y; Zhang, K; Zhu, C, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, K | 1 |
| Wang, M | 1 |
| Yao, Y | 1 |
| Huang, T | 1 |
| Liu, F | 1 |
| Zhu, C | 1 |
| Lin, C | 1 |
| Searashi, Y | 1 |
| Matsudaira, H | 1 |
| Takagi, I | 1 |
| Steinbrecher, UP | 1 |
| Mishkin, S | 1 |
| Abi-Mansur, P | 1 |
| Ardiaca, MC | 1 |
| Allam, C | 1 |
| Shamma'a, M | 1 |
| Stevenson, DK | 1 |
| Christie, DL | 1 |
| Haas, JE | 1 |
| Talbot, IC | 1 |
| Hofer, T | 1 |
| Becker, EW | 1 |
| Weigand, K | 1 |
| Berg, PA | 1 |
| Horák, J | 1 |
| Mertl, L | 1 |
| Hrabal, P | 1 |
| Fowle, AS | 1 |
| Zorab, PA | 1 |
2 reviews available for sulfamethoxazole and Bile Duct Obstruction
| Article | Year |
|---|---|
[Drug-induced cholestasis].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antineoplastic Agen | 2007 |
Acute liver injury.
Topics: Acetaminophen; Acute Disease; Chemical and Drug Induced Liver Injury; Cholestasis; Halothane; Hepati | 1975 |
7 other studies available for sulfamethoxazole and Bile Duct Obstruction
| Article | Year |
|---|---|
Pharmacokinetic study of seven bioactive components of Xiaoyan Lidan Formula in cholestatic and control rats using UPLC-MS/MS.
Topics: Animals; Biotransformation; Cholestasis; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal | 2021 |
Sulfamethoxazole-induced hepatic injury.
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Female; Humans; Jaundice | 1981 |
Trimethoprim-sulfamethoxazole-induced cholestasis.
Topics: Biopsy; Cholestasis; Female; Humans; Liver; Middle Aged; Sulfamethoxazole; Trimethoprim | 1981 |
Hepatic injury in a child caused by trimethoprim-sulfamethoxazole.
Topics: Adolescent; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Combinations; Drug Hyp | 1978 |
Demonstration of sensitized lymphocytes to trimethoprim/sulfamethoxazole and ofloxacin in a patient with cholestatic hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Female; Humans; O | 1992 |
[Acute liver failure and severe cholestasis due to sulfonamides].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Combinations; Female; Hepatic Encep | 1985 |
Esch. coli endocarditis successfully treated with oral trimethoprim and sulphamethoxazole.
Topics: Adult; Cholestasis; Endocarditis, Subacute Bacterial; Escherichia coli; Escherichia coli Infections; | 1970 |