sulfamethoxazole has been researched along with Ascorbic Acid Deficiency in 2 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
Ascorbic Acid Deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfonamide antimicrobials such as sulfamethoxazole (SMX) have been associated with drug hypersensitivity reactions, particularly in patients with AIDS." | 3.76 | Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine. ( Abouraya, M; Bhusari, S; Drescher, NJ; Padilla, ML; Pinkerton, ME; Sacco, JC; Trepanier, LA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhusari, S | 1 |
| Abouraya, M | 1 |
| Padilla, ML | 1 |
| Pinkerton, ME | 1 |
| Drescher, NJ | 1 |
| Sacco, JC | 1 |
| Trepanier, LA | 2 |
| Yoder, AR | 1 |
| Bajad, S | 1 |
| Beckwith, MD | 1 |
| Bellehumeur, JL | 1 |
| Graziano, FM | 1 |
2 other studies available for sulfamethoxazole and Ascorbic Acid Deficiency
| Article | Year |
|---|---|
Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine.
Topics: Animals; Anti-Infective Agents; Antioxidants; Ascorbic Acid; Ascorbic Acid Deficiency; Cell Prolifer | 2010 |
Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
Topics: Adult; Anti-Infective Agents; Ascorbic Acid; Ascorbic Acid Deficiency; Case-Control Studies; CD4-CD8 | 2004 |