sulfamethoxazole has been researched along with Allergy, Drug in 116 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections." | 9.05 | Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections. ( de Jersey, P; Wooller, HO, 1982) |
| "To utilize T cells from sulfamethoxazole (SMX) hypersensitive patients with cystic fibrosis to examine the HLA molecules that interact with nitroso SMX (SMX-NO)-derived antigens." | 7.81 | HLA-DQ allele-restricted activation of nitroso sulfamethoxazole-specific CD4-positive T lymphocytes from patients with cystic fibrosis. ( Alfirevic, A; Baker, DM; Faulkner, L; Naisbitt, DJ; Ogese, MO; Park, BK; Peckham, D; Pirmohamed, M; Saide, K; Sette, A; Whitaker, P, 2015) |
| "To compare mechanisms of antigen presentation and characterize the phenotype and function of T cells from sulfamethoxazole-hypersensitive patients with and without cystic fibrosis." | 7.77 | Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis. ( Callan, H; Castrejon, L; El-Ghaiesh, S; Elsheikh, A; Farrell, J; Lavergne, SN; Monshi, M; Naisbitt, DJ; Park, BK; Peckham, D; Pichler, WJ; Whitaker, P, 2011) |
| "Sulfamethoxazole (SMX) is an important antibiotic in the management of patients with cystic fibrosis, but allergic reactions may develop thus restricting therapy." | 7.76 | Drug metabolite-specific lymphocyte responses in sulfamethoxazole allergic patients with cystic fibrosis. ( Conway, S; Lavergne, SN; Naisbitt, DJ; Park, BK; Peckham, D; Whitaker, P, 2010) |
| "Intravenous administration of trimethoprim-sulfamethoxazole (TMS) on three occasions resulted in fever, rash, and wheezing in a 30-year-old man with acquired immunodeficiency syndrome with Pneumocytis carinii pneumonia." | 7.67 | Oral desensitization to trimethoprim-sulfamethoxazole in a patient with acquired immunodeficiency syndrome. ( Finegold, I, 1986) |
| "In three of eight patients with the acquired immune deficiency syndrome the Pneumocystis carinii pneumonia treated with intravenous trimethoprim sulfamethoxazole, drug-related reactions occurred 9, 10, and 13 days after therapy." | 7.67 | Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia. ( Brunner, E; Haddad, ZH; Sainz, C; White, MV, 1989) |
| " Only 5 of 37 patients started on trimethoprim-sulfamethoxazole were able to complete treatment; in 29 patients drug toxicity occurred and in 19 treatment was changed due to adverse reactions that included rash, fever, neutropenia, thrombocytopenia, and transaminase elevation." | 7.67 | Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. ( Gordin, FM; Mills, J; Simon, GL; Wofsy, CB, 1984) |
| "Hypersensitivity adverse drug reactions are much more common among patients with acquired immunodeficiency syndrome (AIDS) than in the general population." | 5.33 | Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro. ( Dekaban, GA; Rieder, MJ; Wijsman, JA, 2005) |
| "A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections." | 5.05 | Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections. ( de Jersey, P; Wooller, HO, 1982) |
| "To utilize T cells from sulfamethoxazole (SMX) hypersensitive patients with cystic fibrosis to examine the HLA molecules that interact with nitroso SMX (SMX-NO)-derived antigens." | 3.81 | HLA-DQ allele-restricted activation of nitroso sulfamethoxazole-specific CD4-positive T lymphocytes from patients with cystic fibrosis. ( Alfirevic, A; Baker, DM; Faulkner, L; Naisbitt, DJ; Ogese, MO; Park, BK; Peckham, D; Pirmohamed, M; Saide, K; Sette, A; Whitaker, P, 2015) |
| "To compare mechanisms of antigen presentation and characterize the phenotype and function of T cells from sulfamethoxazole-hypersensitive patients with and without cystic fibrosis." | 3.77 | Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis. ( Callan, H; Castrejon, L; El-Ghaiesh, S; Elsheikh, A; Farrell, J; Lavergne, SN; Monshi, M; Naisbitt, DJ; Park, BK; Peckham, D; Pichler, WJ; Whitaker, P, 2011) |
| "Sulfonamide antimicrobials such as sulfamethoxazole (SMX) have been associated with drug hypersensitivity reactions, particularly in patients with AIDS." | 3.76 | Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine. ( Abouraya, M; Bhusari, S; Drescher, NJ; Padilla, ML; Pinkerton, ME; Sacco, JC; Trepanier, LA, 2010) |
| "Sulfamethoxazole (SMX) is an important antibiotic in the management of patients with cystic fibrosis, but allergic reactions may develop thus restricting therapy." | 3.76 | Drug metabolite-specific lymphocyte responses in sulfamethoxazole allergic patients with cystic fibrosis. ( Conway, S; Lavergne, SN; Naisbitt, DJ; Park, BK; Peckham, D; Whitaker, P, 2010) |
| " the LTA by using trypan blue exclusion and to determine the utility of the assay to confirm drug hypersensitivity syndrome (DHS) to sulphonamides (SMX) and aromatic anticonvulsants." | 3.70 | A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes. ( Malkiewicz, IM; Neuman, MG; Shear, NH, 2000) |
| "Intravenous administration of trimethoprim-sulfamethoxazole (TMS) on three occasions resulted in fever, rash, and wheezing in a 30-year-old man with acquired immunodeficiency syndrome with Pneumocytis carinii pneumonia." | 3.67 | Oral desensitization to trimethoprim-sulfamethoxazole in a patient with acquired immunodeficiency syndrome. ( Finegold, I, 1986) |
| "An immunoassay was developed for the detection of sulfamethoxazole reactive IgE antibodies in the sera of patients who experienced life threatening anaphylactic reactions following the ingestion of co-trimoxazole (trimethoprim and sulfamethoxazole)." | 3.67 | Drugs as allergens: detection and combining site specificities of IgE antibodies to sulfamethoxazole. ( Baldo, BA; Harle, DG; Wells, JV, 1988) |
| "A patient with acquired immunodeficiency syndrome (AIDS) developed rash, fever, neutropenia, and elevated liver function tests during an initial course of trimethoprim-sulfamethoxazole (TMP-SMX) therapy." | 3.67 | Severe hypersensitivity reaction upon rechallenge with trimethoprim-sulfamethoxazole in a patient with AIDS. ( Arnold, PA; Guglielmo, BJ; Hollander, H, 1988) |
| "In three of eight patients with the acquired immune deficiency syndrome the Pneumocystis carinii pneumonia treated with intravenous trimethoprim sulfamethoxazole, drug-related reactions occurred 9, 10, and 13 days after therapy." | 3.67 | Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia. ( Brunner, E; Haddad, ZH; Sainz, C; White, MV, 1989) |
| " Only 5 of 37 patients started on trimethoprim-sulfamethoxazole were able to complete treatment; in 29 patients drug toxicity occurred and in 19 treatment was changed due to adverse reactions that included rash, fever, neutropenia, thrombocytopenia, and transaminase elevation." | 3.67 | Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. ( Gordin, FM; Mills, J; Simon, GL; Wofsy, CB, 1984) |
| "A patient with several episodes of jaundice associated with sulfamethoxazole therapy is described." | 3.66 | Sulfamethoxazole-induced hepatic injury. ( Mishkin, S; Steinbrecher, UP, 1981) |
| "After an acute course of pharyngitis and bronchitis treated with Bactrim (trimethoprim and sulfamethoxazol), a 52 year old woman suddenly developed a widespread, sterile pustular eruption with predilection of the distal parts of the extremities." | 3.66 | [Generalized acute pustulosis. An unusual presentation of leukocytoclastic vasculitis]. ( Braun-Falco, O; Luderschmidt, C; Maciejewski, W; Scherer, R, 1978) |
| "Sulfamethoxazole (SMX) is an effective drug for the management of opportunistic infections, but its use is limited by hypersensitivity reactions, particularly in HIV-infected patients." | 2.72 | Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso. ( Bajad, SU; Graziano, FM; Guzinski, MV; Kurian, JR; Lavergne, SN; Maki, JE; Trepanier, LA; Yoder, AR, 2006) |
| "The differential incidence of adverse drug reactions (ADR) between trimethoprim-sulfamethoxazole and dapsone might be explained, in part, by differences in the inherent toxicity of the hydroxylamine metabolites of sulfamethoxazole and dapsone." | 2.69 | Comparison of the in vitro cytotoxicity of hydroxylamine metabolites of sulfamethoxazole and dapsone. ( Bellevue, FH; Reilly, TP; Svensson, CK; Woster, PM, 1998) |
| "The onset of cutaneous adverse effects attributable to sulfamethoxazole-trimethoprim therapy within 3 months after desensitization." | 2.68 | Efficacy and safety of desensitization with sulfamethoxazole and trimethoprim in 48 previously hypersensitive patients infected with human immunodeficiency virus. ( Bricaire, F; Caumes, E; Guermonprez, G; Katlama, C; Lecomte, C, 1997) |
| "Hypersensitivity syndromes are severe drug induced side effects with skin rashes, fever and/or multiorgan-system abnormalities which are not pharmacologically related." | 2.40 | [Drug-induced hypersensitivity syndrome. A review and presentation of 2 personal cases]. ( Pichler, WJ; Schnyder, B; Zanni, MP, 1997) |
| " The data also provide evidence that accumulation of toxic reactive metabolites could be an important component in the cascade of events leading to the development of DHRs in CF patients." | 1.91 | Drug Hypersensitivity Reactions in Patients with Cystic Fibrosis: Potential Value of the Lymphocyte Toxicity Assay to Assess Risk. ( Abuzgaia, AM; Elzagallaai, AA; Mullowney, T; Rieder, MJ, 2023) |
| "Drug hypersensitivity reactions (DHRs) are rare but potentially fatal adverse drug reactions (ADRs)." | 1.39 | The predictive value of the in vitro platelet toxicity assay (iPTA) for the diagnosis of hypersensitivity reactions to sulfonamides. ( Elzagallaai, AA; Koren, G; Rieder, MJ, 2013) |
| " Anti-drug antibodies were also found in dogs experimentally dosed with SMX-nitroso followed by SMX, but not in a dog dosed with drug vehicle, followed by SMX." | 1.33 | Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity. ( Danhof, RS; Lavergne, SN; Trepanier, LA; Volkman, EM, 2006) |
| "Hypersensitivity adverse drug reactions are much more common among patients with acquired immunodeficiency syndrome (AIDS) than in the general population." | 1.33 | Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro. ( Dekaban, GA; Rieder, MJ; Wijsman, JA, 2005) |
| " Dosing was by the intraperitoneal route, once daily for four consecutive days per week, for 2 weeks total, followed by a third week of observation." | 1.33 | Evaluation of the clinical, immunologic, and biochemical effects of nitroso sulfamethoxazole administration to dogs: a pilot study. ( Lavergne, SN; Maki, JE; Trepanier, LA; Volkman, EM; Yoder, AR, 2005) |
| " Male Wistar rats were dosed with sulphamethoxazole, sulphamethoxazole hydroxylamine or nitroso sulphamethoxazole." | 1.31 | Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo. ( Burkhart, C; Cribb, AE; Gordon, SF; Naisbitt, DJ; Park, BK; Pichler, WJ; Pirmohamed, M, 2001) |
| " The immunogenic potential of SMX and its metabolites, SMX-NOH and SMX-NO, were assessed in rats by analyzing serum samples for the presence of anti-SMX IgG antibodies during a 4-week dosing period." | 1.30 | The relationship between the disposition and immunogenicity of sulfamethoxazole in the rat. ( Gill, HJ; Hough, SJ; Kitteringham, NR; Maggs, JL; Naisbitt, DJ; Park, BK; Pirmohamed, M, 1997) |
| " For a better understanding of the molecular basis of the recognition of such drugs by specific TCC, we investigated 1) the fine specificity of the recognizing TCR, 2) the dose-response relationship for the induction of proliferation or cytokine production, and 3) the mechanism of TCR triggering." | 1.30 | Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human alpha beta+ T cell clones. ( Burkhart, C; Frutig, K; Pichler, WJ; Schnyder, B; von Greyerz, S; Zanni, MP, 1999) |
| "It has been suggested that the high rates of adverse reactions to sulfonamides among patients with AIDS may be related to an increased sensitivity to reactive drug metabolites among HIV-infected cells." | 1.29 | Toxicity of sulfonamide-reactive metabolites in HIV-infected, HTLV-infected, and noninfected cells. ( Bird, IA; Dekaban, GA; Krause, R; Rieder, MJ, 1995) |
| "An undoubtable role of the melioidosis germ persistence in the form of L-variants with the development of DTH in the relapses of the disease was stated." | 1.29 | [Laboratory control of effectiveness of chemotherapy in melioidosis]. ( Antonov, IuV; Batmanov, VP; Iliukhin, VI, 1995) |
| " In addition, heterogeneity in cellular repair mechanisms and the diversity of the human immune response [22] may also contribute to the manifestation of the toxic effects of sulphonamides." | 1.28 | Glutathione transferase mu deficiency is not a marker for predisposition to sulphonamide toxicity. ( Cribb, AE; Riley, RJ; Spielberg, SP, 1991) |
| "Thirty-four homosexual patients with AIDS were treated for Pneumocystis carinii pneumonia between April 1984 and November 1985." | 1.28 | Successful prophylaxis of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in AIDS patients with previous allergic reactions. ( Seitzman, PA; Shafer, RW; Tapper, ML, 1989) |
| "Clinical features of 49 episodes of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome were compared with those of 39 episodes in patients with other immunosuppressive diseases." | 1.27 | Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. ( Hiemenz, JW; Honig, C; Kovacs, JA; Lane, HC; Longo, DL; Macher, AM; Murray, HW; Shelhamer, J; Stover, D; Urmacher, C, 1984) |
| "Sulfamethoxazole (SMX) was coupled to CNBr-activated cellulose disks to form a matrix predominantly substituted with isourea-linked N4-SMX determinants." | 1.27 | Studies of human IgE to a sulfonamide determinant. ( Carrington, DM; Earl, HS; Sullivan, TJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (47.41) | 18.7374 |
| 1990's | 24 (20.69) | 18.2507 |
| 2000's | 19 (16.38) | 29.6817 |
| 2010's | 15 (12.93) | 24.3611 |
| 2020's | 3 (2.59) | 2.80 |
| Authors | Studies |
|---|---|
| Abuzgaia, AM | 2 |
| Elzagallaai, AA | 4 |
| Mullowney, T | 1 |
| Rieder, MJ | 9 |
| Sultan, EA | 1 |
| Bend, JR | 1 |
| Loubani, E | 1 |
| Pereira, ARF | 1 |
| Aun, MV | 1 |
| Kelmann, NCP | 1 |
| Motta, AA | 1 |
| Kalil, J | 1 |
| Giavina-Bianchi, P | 1 |
| Gibson, A | 2 |
| Faulkner, L | 3 |
| Lichtenfels, M | 1 |
| Ogese, M | 1 |
| Al-Attar, Z | 1 |
| Alfirevic, A | 4 |
| Esser, PR | 1 |
| Martin, SF | 1 |
| Pirmohamed, M | 10 |
| Park, BK | 14 |
| Naisbitt, DJ | 17 |
| Monroy-Arreola, A | 1 |
| Durán-Figueroa, NV | 1 |
| Méndez-Flores, S | 1 |
| Domínguez-Cherit, J | 1 |
| Watkinson, J | 1 |
| Badillo-Corona, JA | 1 |
| Whitaker, P | 4 |
| Castrejón-Flores, JL | 1 |
| Tamura, A | 1 |
| Miyawaki, I | 1 |
| Yamada, T | 1 |
| Kimura, J | 1 |
| Funabashi, H | 1 |
| Koren, G | 2 |
| Ogese, MO | 1 |
| Saide, K | 1 |
| Peckham, D | 3 |
| Baker, DM | 1 |
| Sette, A | 1 |
| Sullivan, A | 1 |
| Tailor, A | 1 |
| Usui, T | 1 |
| Kevin Park, B | 1 |
| Kuretski, J | 1 |
| Dahya, V | 1 |
| Cason, L | 1 |
| Chalasani, P | 1 |
| Ramgopal, M | 1 |
| Lavergne, SN | 6 |
| Wang, H | 1 |
| Callan, HE | 1 |
| Pichler, WJ | 11 |
| Castrejon, JL | 1 |
| Berry, N | 1 |
| El-Ghaiesh, S | 2 |
| Gerber, B | 1 |
| Bhusari, S | 1 |
| Abouraya, M | 2 |
| Padilla, ML | 1 |
| Pinkerton, ME | 1 |
| Drescher, NJ | 1 |
| Sacco, JC | 2 |
| Trepanier, LA | 6 |
| Zawodniak, A | 1 |
| Lochmatter, P | 1 |
| Beeler, A | 1 |
| Conway, S | 1 |
| Kahl, BS | 1 |
| Elsheikh, A | 1 |
| Castrejon, L | 1 |
| Monshi, M | 1 |
| Callan, H | 1 |
| Farrell, J | 2 |
| Eyanagi, R | 1 |
| Toda, A | 1 |
| Imoto, M | 1 |
| Uchiyama, H | 1 |
| Ishii, Y | 1 |
| Kuroki, H | 1 |
| Kuramoto, Y | 1 |
| Soeda, S | 1 |
| Shimeno, H | 1 |
| Gordon, F | 1 |
| Burkhart, C | 4 |
| Britschgi, M | 2 |
| Strasser, I | 1 |
| Depta, JP | 2 |
| von Greyerz, S | 4 |
| Barnaba, V | 1 |
| Stalford, AC | 2 |
| Vilar, FJ | 2 |
| Wilkins, EG | 2 |
| Hopkins, JE | 1 |
| Humphreys, N | 1 |
| Dearman, RJ | 1 |
| Kimber, I | 1 |
| Volkman, EM | 2 |
| Maki, JE | 2 |
| Yoder, AR | 2 |
| Wijsman, JA | 1 |
| Dekaban, GA | 2 |
| Kurian, JR | 1 |
| Bajad, SU | 1 |
| Guzinski, MV | 1 |
| Graziano, FM | 1 |
| Danhof, RS | 1 |
| Figueroa, J | 1 |
| Ortega, N | 1 |
| Almeida, L | 1 |
| Blanco, C | 1 |
| Castillo, R | 1 |
| Sanderson, JP | 1 |
| Ashby, CA | 1 |
| Tucker, MJ | 1 |
| Clarke, SE | 1 |
| Dujovne, CA | 1 |
| Chan, CH | 1 |
| Zimmerman, HJ | 1 |
| Schainuck, LI | 1 |
| Hano, JE | 1 |
| Clark, AJ | 1 |
| Mouchizadeh, J | 1 |
| Faunch, R | 1 |
| McMichael, HB | 1 |
| Lennon, D | 1 |
| Gordin, FM | 1 |
| Simon, GL | 1 |
| Wofsy, CB | 1 |
| Mills, J | 1 |
| Kovacs, JA | 1 |
| Hiemenz, JW | 1 |
| Macher, AM | 1 |
| Stover, D | 1 |
| Murray, HW | 1 |
| Shelhamer, J | 1 |
| Lane, HC | 1 |
| Urmacher, C | 1 |
| Honig, C | 1 |
| Longo, DL | 1 |
| Burt, RA | 1 |
| Boghaert, A | 1 |
| Moulaert, P | 1 |
| Nollet, G | 1 |
| Bellon, A | 1 |
| Kremer, I | 1 |
| Ritz, R | 1 |
| Brunner, F | 1 |
| Cohn, DL | 1 |
| Penley, KA | 1 |
| Judson, FN | 1 |
| Kirkpatrick, CH | 1 |
| Horsburgh, CR | 1 |
| Davis, KC | 1 |
| Warrington, RJ | 1 |
| Sauder, PJ | 1 |
| McPhillips, S | 1 |
| Adiga, KM | 1 |
| de Jersey, P | 1 |
| Wooller, HO | 1 |
| Steinbrecher, UP | 1 |
| Mishkin, S | 1 |
| Chanu, B | 1 |
| Kernbaum, S | 1 |
| Uzzan, B | 1 |
| Faille, A | 1 |
| Blasetti, A | 1 |
| Rouffy, J | 1 |
| Nenci, GG | 1 |
| Agnelli, G | 1 |
| Berrettini, M | 1 |
| Hertl, M | 1 |
| Jugert, F | 1 |
| Merk, HF | 1 |
| Batmanov, VP | 1 |
| Iliukhin, VI | 1 |
| Antonov, IuV | 1 |
| Daftarian, MP | 1 |
| Filion, LG | 1 |
| Cameron, W | 1 |
| Conway, B | 1 |
| Roy, R | 1 |
| Tropper, F | 1 |
| Diaz-Mitoma, F | 1 |
| Meekins, CV | 1 |
| Sullivan, TJ | 2 |
| Gruchalla, RS | 2 |
| Krause, R | 1 |
| Bird, IA | 1 |
| Agarwal, BR | 1 |
| Sathe, AS | 1 |
| Currimbhoy, Z | 1 |
| Carr, A | 1 |
| Tindall, B | 1 |
| Penny, R | 1 |
| Cooper, DA | 1 |
| Cribb, AE | 4 |
| Lee, BL | 1 |
| Spielberg, SP | 4 |
| Zanni, MP | 3 |
| Schnyder, B | 4 |
| Mauri-Hellweg, D | 2 |
| Brander, C | 1 |
| Kalbermatten, C | 1 |
| Caumes, E | 1 |
| Guermonprez, G | 1 |
| Lecomte, C | 1 |
| Katlama, C | 1 |
| Bricaire, F | 1 |
| Zanni, M | 1 |
| Bettens, F | 1 |
| Gill, HJ | 2 |
| Hough, SJ | 2 |
| Maggs, JL | 1 |
| Kitteringham, NR | 2 |
| Rich, JD | 1 |
| Sullivan, T | 1 |
| Greineder, D | 1 |
| Kazanjian, PH | 1 |
| Pesenko, RD | 1 |
| Do, TT | 1 |
| Skiest, DJ | 1 |
| Reilly, TP | 2 |
| Bellevue, FH | 1 |
| Woster, PM | 2 |
| Svensson, CK | 2 |
| Frutig, K | 1 |
| MacArthur, RD | 1 |
| Farrough, MJ | 1 |
| Crane, LR | 1 |
| Bedard, K | 1 |
| Smith, S | 1 |
| Cribb, A | 1 |
| Neuman, MG | 1 |
| Malkiewicz, IM | 1 |
| Shear, NH | 3 |
| Park, KB | 1 |
| Choquet-Kastylevsky, G | 1 |
| Santolaria, N | 1 |
| Tedone, R | 1 |
| Aujoulat, M | 1 |
| Descotes, J | 1 |
| Gordon, SF | 1 |
| Richmond, JM | 1 |
| Whitworth, JA | 1 |
| Fairley, KF | 1 |
| Kincaid-Smith, P | 1 |
| Kunz, HD | 1 |
| Friess, G | 1 |
| Hirschfeld, E | 1 |
| Azinge, NO | 1 |
| Garrick, GA | 1 |
| Stevenson, DK | 1 |
| Christie, DL | 1 |
| Haas, JE | 1 |
| Braun-Falco, O | 1 |
| Luderschmidt, C | 1 |
| Maciejewski, W | 1 |
| Scherer, R | 1 |
| Juul, P | 1 |
| Lynn, KL | 1 |
| Little, PJ | 1 |
| Brathwaite, AR | 1 |
| Dry, J | 1 |
| Leynadier, F | 1 |
| Herman, D | 1 |
| Pradalier, A | 1 |
| André, JM | 1 |
| Hofer, T | 1 |
| Becker, EW | 1 |
| Weigand, K | 1 |
| Berg, PA | 2 |
| Gupta, A | 1 |
| Eggo, MC | 1 |
| Uetrecht, JP | 1 |
| Daneman, D | 1 |
| Cannon, M | 2 |
| Riley, RJ | 1 |
| O'Neil, CE | 1 |
| Reed, MA | 1 |
| Lopez, M | 1 |
| Hyslop, N | 1 |
| Gutierrez, E | 1 |
| Salvaggio, J | 1 |
| Greenberger, PA | 1 |
| Carrington, DM | 1 |
| Earl, HS | 1 |
| White, MV | 1 |
| Haddad, ZH | 1 |
| Brunner, E | 1 |
| Sainz, C | 1 |
| Shafer, RW | 1 |
| Seitzman, PA | 1 |
| Tapper, ML | 1 |
| Ulstad, DR | 1 |
| Ampel, NM | 1 |
| Shon, BY | 1 |
| Galgiani, JN | 1 |
| Cutcher, AB | 1 |
| Papakonstantinou, G | 2 |
| Füessl, H | 2 |
| Matuschke, A | 1 |
| Hehlmann, R | 2 |
| Gottlieb, MS | 1 |
| Young, LS | 1 |
| Uetrecht, J | 1 |
| Miller, M | 1 |
| Arnold, PA | 1 |
| Guglielmo, BJ | 1 |
| Hollander, H | 1 |
| Pioda, GB | 2 |
| Del Favero, A | 2 |
| Menichetti, F | 2 |
| Spinozzi, F | 1 |
| Gernini, I | 2 |
| Rambotti, P | 2 |
| Tanabe, K | 1 |
| Nakagawa, A | 1 |
| Kimura, S | 1 |
| Mitamura, K | 1 |
| Shimada, K | 1 |
| Mori, S | 1 |
| Wakabayashi, T | 1 |
| Inagaki, M | 1 |
| Miura, T | 1 |
| Harle, DG | 2 |
| Baldo, BA | 2 |
| Wells, JV | 1 |
| Sanders, PS | 1 |
| Daniel, PT | 1 |
| Guerciolini, R | 1 |
| Wälti, M | 1 |
| Neftel, KA | 1 |
| Cohen, M | 1 |
| Winkler, P | 1 |
| de Weck, AL | 1 |
| Smal, MA | 1 |
| Van Nunen, SA | 1 |
| Finegold, I | 1 |
| Gibbons, RB | 1 |
| Lindauer, JA | 1 |
| Acero, D | 1 |
| Masabeu, A | 1 |
| Alabern, C | 1 |
| Oterino, A | 1 |
| Mayer, KH | 1 |
| DeTorres, OH | 1 |
| Christiansen, AH | 1 |
| Klein, U | 1 |
| Gikalov, I | 1 |
| Keller, M | 1 |
| Hoigné, R | 1 |
| Halpern, G | 1 |
| Münnich, D | 1 |
| Brumfitt, W | 1 |
| Pursell, R | 1 |
| Gavras, H | 1 |
| Lawson, DH | 1 |
| Linton, AL | 1 |
5 reviews available for sulfamethoxazole and Allergy, Drug
| Article | Year |
|---|---|
The danger hypothesis--potential role in idiosyncratic drug reactions.
Topics: Animals; Anti-Infective Agents; Antigen-Presenting Cells; Drug Hypersensitivity; Drug-Related Side E | 2002 |
Drug hypersensitivity reactions in skin: understanding mechanisms and the development of diagnostic and predictive tests.
Topics: Animals; Anti-Infective Agents; Cells, Cultured; Dermatitis, Allergic Contact; Drug Hypersensitivity | 2004 |
Adverse reactions to sulphonamide and sulphonamide-trimethoprim antimicrobials: clinical syndromes and pathogenesis.
Topics: Anti-Infective Agents; Drug Combinations; Drug Hypersensitivity; Humans; Sulfamethoxazole; Sulfamoxo | 1996 |
[Drug-induced hypersensitivity syndrome. A review and presentation of 2 personal cases].
Topics: Adult; Aged; Allopurinol; CD8 Antigens; Drug Eruptions; Drug Hypersensitivity; Female; HLA-DR Antige | 1997 |
Current guidelines on the use of antibacterial drugs in patients with malignancies.
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Antibody Formation; Bacterial Infecti | 1985 |
11 trials available for sulfamethoxazole and Allergy, Drug
| Article | Year |
|---|---|
Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Cell Separation; Cyclic N-Oxides; Drug Hypersensitivity; F | 2006 |
Sulfonamide allergy without cross-reactivity to celecoxib.
Topics: Adolescent; Adult; Bronchial Provocation Tests; Celecoxib; Cross Reactions; Drug Hypersensitivity; F | 2007 |
Trimethoprim alone.
Topics: Adult; Clinical Trials as Topic; Drug Combinations; Drug Hypersensitivity; Humans; Male; Sulfamethox | 1980 |
Review of adverse reactions associated with cinoxacin and other drugs used to treat urinary tract infections.
Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents, Urinary; Central Nervous System Diseases; Cinoxacin | 1984 |
Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Cinoxacin; Clinical Trials as | 1982 |
Efficacy and safety of desensitization with sulfamethoxazole and trimethoprim in 48 previously hypersensitive patients infected with human immunodeficiency virus.
Topics: Adult; Anti-Infective Agents; Desensitization, Immunologic; Drug Administration Schedule; Drug Erupt | 1997 |
Comparison of the in vitro cytotoxicity of hydroxylamine metabolites of sulfamethoxazole and dapsone.
Topics: Cell Survival; Dapsone; Drug Hypersensitivity; Erythrocytes; Humans; Hydroxylamine; In Vitro Techniq | 1998 |
Is hydroxylamine-induced cytotoxicity a valid marker for hypersensitivity reactions to sulfamethoxazole in human immunodeficiency virus-infected individuals?
Topics: Adult; Anti-Infective Agents; Benzoxazoles; Biomarkers; Cell Separation; Cell Survival; Dapsone; Dru | 1999 |
Treatment of gonorrhea in the male with trimethoprim-sulfamethoxazole using a one- or two-dose regimen.
Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Drug Combinations; Drug Evaluatio | 1975 |
[Radioimmunologic detection of IgE and IgG antibodies against drugs. Conclusions after experience with over 1200 patients].
Topics: Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Hypersensitivity; Flavonoids; Hum | 1986 |
Double-blind trial to compare ampicillin, cephalexin, co-trimoxazole, and trimethoprim in treatment of urinary infection.
Topics: Ampicillin; Bacteriuria; Cephalexin; Cephalosporins; Drug Hypersensitivity; Escherichia coli Infecti | 1972 |
100 other studies available for sulfamethoxazole and Allergy, Drug
| Article | Year |
|---|---|
Drug Hypersensitivity Reactions in Patients with Cystic Fibrosis: Potential Value of the Lymphocyte Toxicity Assay to Assess Risk.
Topics: Anti-Bacterial Agents; Cystic Fibrosis; Drug Hypersensitivity; Humans; Lymphocytes; Sulfamethoxazole | 2023 |
Role of Oxidative Stress in Hypersensitivity Reactions to Sulfonamides.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Blood Platelets; Cell Survival; Child; Drug Hypersen | 2020 |
Loss of tolerance 5 days after discontinuing sulphonamide introduced via desensitization in delayed reaction.
Topics: Aged; Desensitization, Immunologic; Drug Eruptions; Drug Hypersensitivity; Humans; Male; Sulfamethox | 2020 |
The Effect of Inhibitory Signals on the Priming of Drug Hapten-Specific T Cells That Express Distinct Vβ Receptors.
Topics: CD4-Positive T-Lymphocytes; CTLA-4 Antigen; Drug Hypersensitivity; Haptens; Hepatitis A Virus Cellul | 2017 |
Up-Regulation of T-Cell Activation MicroRNAs in Drug-Specific CD4
Topics: Adult; Carbamazepine; CD4-Positive T-Lymphocytes; Cytokines; Drug Hypersensitivity; Female; Humans; | 2018 |
Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensiti
Topics: Administration, Oral; Amoxicillin; Animals; Biomarkers; Carbamazepine; Drug Hypersensitivity; Flow C | 2013 |
The predictive value of the in vitro platelet toxicity assay (iPTA) for the diagnosis of hypersensitivity reactions to sulfonamides.
Topics: Adolescent; Adult; Aged; Blood Platelets; Case-Control Studies; Child; Dose-Response Relationship, D | 2013 |
HLA-DQ allele-restricted activation of nitroso sulfamethoxazole-specific CD4-positive T lymphocytes from patients with cystic fibrosis.
Topics: Alleles; CD4-Positive T-Lymphocytes; Cell Proliferation; Cystic Fibrosis; Drug Hypersensitivity; Fem | 2015 |
Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.
Topics: Adult; Biological Specimen Banks; Cell Proliferation; Cells, Cultured; Coculture Techniques; Cytokin | 2016 |
Nocardia Bacteremia and Endocarditis in a Patient With a Sulfa Allergy.
Topics: Amikacin; Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Drug Hypersensitivity; Dyspnea; Endocard | 2016 |
"Danger" conditions increase sulfamethoxazole-protein adduct formation in human antigen-presenting cells.
Topics: Anti-Infective Agents; Antigen-Presenting Cells; B-Lymphocytes; Cell Line; Cyclohexanones; Cytokines | 2009 |
Predicting drug hypersensitivity by in vitro tests.
Topics: Allergens; Antigen-Antibody Reactions; Antigens; Drug Hypersensitivity; Haptens; Humans; Nitroso Com | 2007 |
Stimulation of human T cells with sulfonamides and sulfonamide metabolites.
Topics: Anti-Infective Agents; Antigen Presentation; Clone Cells; Drug Hypersensitivity; Humans; Lymphocyte | 2010 |
Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine.
Topics: Animals; Anti-Infective Agents; Antioxidants; Ascorbic Acid; Ascorbic Acid Deficiency; Cell Prolifer | 2010 |
The in vitro platelet toxicity assay (iPTA): a novel approach for assessment of drug hypersensitivity syndrome.
Topics: Adult; Animals; Anti-Infective Agents; Anticonvulsants; Blood Platelets; Carbamazepine; Cell Surviva | 2011 |
Cross-reactivity in drug hypersensitivity reactions to sulfasalazine and sulfamethoxazole.
Topics: Adult; Aged; Anti-Infective Agents; Cross Reactions; Drug Hypersensitivity; Female; Humans; Male; Mi | 2010 |
Drug metabolite-specific lymphocyte responses in sulfamethoxazole allergic patients with cystic fibrosis.
Topics: Adolescent; Adult; Anti-Infective Agents; Cystic Fibrosis; Drug Hypersensitivity; Female; Humans; Hy | 2010 |
Evaluation of sulfonamide detoxification pathways in haematologic malignancy patients prior to intermittent trimethoprim-sulfamethoxazole prophylaxis.
Topics: Adult; Aged; Anti-Infective Agents; Ascorbic Acid; Case-Control Studies; Cell Proliferation; Cytochr | 2011 |
Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis.
Topics: Anti-Bacterial Agents; Antigen Presentation; Antigen-Presenting Cells; Case-Control Studies; Cell Pr | 2011 |
Covalent binding of nitroso-sulfonamides to glutathione S-transferase in guinea pigs with delayed type hypersensitivity.
Topics: Animals; Drug Hypersensitivity; Female; Glutathione Transferase; Guinea Pigs; Haptens; Hypersensitiv | 2012 |
Non-covalent presentation of sulfamethoxazole to human CD4+ T cells is independent of distinct human leucocyte antigen-bound peptides.
Topics: Allergens; Antigen-Presenting Cells; CD4-Positive T-Lymphocytes; Cell Division; Coculture Techniques | 2002 |
Slow acetylator phenotype and genotype in HIV-positive patients with sulphamethoxazole hypersensitivity.
Topics: Acetylation; Adult; Drug Hypersensitivity; Genotype; HIV Infections; Humans; Middle Aged; Phenotype; | 2003 |
Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells.
Topics: Animals; Anti-Infective Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; D | 2005 |
Evaluation of the clinical, immunologic, and biochemical effects of nitroso sulfamethoxazole administration to dogs: a pilot study.
Topics: Animals; Anti-Infective Agents; Antibody Formation; Ascorbic Acid; Biotransformation; Cysteine; Dogs | 2005 |
Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro.
Topics: Animals; Anti-Infective Agents; Biotransformation; Cell Line; Cell Survival; Clindamycin; Coculture | 2005 |
Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity.
Topics: Animals; Anti-Infective Agents; Antibody Specificity; Blood Proteins; Cross Reactions; Disease Model | 2006 |
Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.
Topics: Animals; Anti-Infective Agents; Aryl Hydrocarbon Hydroxylases; CD40 Antigens; CD40 Ligand; Cytochrom | 2007 |
Sulfonamide hepatic injury. Review of the literature and report of a case due to sulfamethoxazole.
Topics: Adult; Anuria; Drug Hypersensitivity; Eosinophilia; Humans; Jaundice; Male; Sulfamethoxazole; Sulfon | 1967 |
Bilateral ureteral obstruction following sulfamethoxazole.
Topics: Aged; Diuresis; Drug Hypersensitivity; Humans; Male; Radiography; Sulfamethoxazole; Ureteral Obstruc | 1967 |
Co-trimoxazole toxicity.
Topics: Adult; Drug Combinations; Drug Hypersensitivity; Humans; Sulfamethoxazole; Trimethoprim; Trimethopri | 1984 |
Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; | 1984 |
Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Child; Drug Combinations; Drug Eruption | 1984 |
Identification of the causative antigen in immune complex allergy. A simple method.
Topics: Antigens; Complement System Proteins; Drug Hypersensitivity; Female; Humans; Immune Complex Diseases | 1980 |
Aseptic meningitis as an adverse effect of co-trimoxazole.
Topics: Adult; Drug Combinations; Drug Hypersensitivity; Female; Humans; Meningitis; Meningitis, Aseptic; Su | 1983 |
The acquired immunodeficiency syndrome and a trimethoprim-sulfamethoxazole adverse reaction.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Drug Hypersensitivity; Humans; Male; P | 1984 |
Lymphocyte transformation studies in suspected hypersensitivity to trimethoprim-sulphamethoxazole.
Topics: Adolescent; Adult; Aged; Child; Drug Hypersensitivity; Female; Humans; Lymphocyte Activation; Male; | 1983 |
Conjunctival photosensitivity to co-trimoxazole.
Topics: Conjunctival Diseases; Drug Combinations; Drug Hypersensitivity; Humans; Male; Middle Aged; Sulfamet | 1982 |
Sulfamethoxazole-induced hepatic injury.
Topics: Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Female; Humans; Jaundice | 1981 |
[Bone marrow aplasia induced by sulfamethoxazole-trimethoprim. Evidence of an allergic mechanism].
Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Pancytopenia; Sulfamethoxazole; Trimethoprim | 1981 |
[Acute immunoallergic thrombopenia due to sulfamethoxazole-trimethoprim].
Topics: Acute Disease; Drug Hypersensitivity; Humans; Sulfamethoxazole; Thrombocytopenia; Trimethoprim | 1980 |
CD8+ dermal T cells from a sulphamethoxazole-induced bullous exanthem proliferate in response to drug-modified liver microsomes.
Topics: Aged; Animals; CD8 Antigens; CD8-Positive T-Lymphocytes; Cytochrome P-450 Enzyme System; Drug Hypers | 1995 |
[Laboratory control of effectiveness of chemotherapy in melioidosis].
Topics: Animals; Anti-Bacterial Agents; Burkholderia pseudomallei; Complement System Proteins; Drug Hypersen | 1995 |
Immune response to sulfamethoxazole in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antibody Formation; Antibody Specificity; Drug Hypersensi | 1995 |
Immunochemical analysis of sulfonamide drug allergy: identification of sulfamethoxazole-substituted human serum proteins.
Topics: Animals; Blood Proteins; Blotting, Western; Drug Hypersensitivity; Goats; Haptens; Protein Binding; | 1994 |
Toxicity of sulfonamide-reactive metabolites in HIV-infected, HTLV-infected, and noninfected cells.
Topics: Adult; Cells, Cultured; Deltaretrovirus Infections; Dose-Response Relationship, Drug; Drug Hypersens | 1995 |
Marked atypical lymphocytosis and skin rash following sulfamethoxazole.
Topics: Drug Eruptions; Drug Hypersensitivity; Humans; Infant; Lymphocytosis; Male; Sulfamethoxazole; Trimet | 1993 |
In vitro cytotoxicity as a marker of hypersensitivity to sulphamethoxazole in patients with HIV.
Topics: Adult; CD4-CD8 Ratio; Cytokines; Cytotoxicity, Immunologic; Drug Hypersensitivity; Glutathione; HIV | 1993 |
T cell reactions in patients showing adverse immune reactions to drugs.
Topics: Adult; Anesthetics, Local; Anti-Infective Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphoc | 1996 |
Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones.
Topics: Antigen-Presenting Cells; Antigens, CD; B-Lymphocytes; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8 | 1997 |
The relationship between the disposition and immunogenicity of sulfamethoxazole in the rat.
Topics: Animals; Antibody Specificity; Biotransformation; Drug Hypersensitivity; Immunoglobulin G; Male; Rat | 1997 |
Trimethoprim/sulfamethoxazole incremental dose regimen in human immunodeficiency virus-infected persons.
Topics: Administration, Oral; Adult; CD4-Positive T-Lymphocytes; Dose-Response Relationship, Drug; Drug Admi | 1997 |
Sulfonamide-induced reactions in desensitized patients with AIDS--the role of covalent protein haptenation by sulfamethoxazole.
Topics: Acquired Immunodeficiency Syndrome; Anti-Infective Agents; CD4 Lymphocyte Count; Drug Hypersensitivi | 1998 |
Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human alpha beta+ T cell clones.
Topics: Clone Cells; Cross Reactions; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Epitop | 1999 |
Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity.
Topics: Adult; Animals; Anti-Infective Agents; Cattle; Cysteine; Dicumarol; Drug Hypersensitivity; Enzyme In | 1999 |
Sequential assessment of an antidrug antibody response in a patient with a systemic delayed-onset sulphonamide hypersensitivity syndrome reaction.
Topics: Adult; Anti-Infective Agents; Blotting, Western; Drug Hypersensitivity; Enzyme-Linked Immunosorbent | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Surviva | 2000 |
Plasma cysteine deficiency and decreased reduction of nitrososulfamethoxazole with HIV infection.
Topics: Adult; Chromatography, High Pressure Liquid; Cysteine; Disease Progression; Drug Hypersensitivity; H | 2000 |
Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells.
Topics: Adult; Anti-Infective Agents; CD4-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Colony-For | 2001 |
Induction of delayed-type hypersensitivity to sulfamethoxazole in mice: role of metabolites.
Topics: Animals; Anti-Infective Agents; CD4 Lymphocyte Count; Disease Models, Animal; Drug Hypersensitivity; | 2001 |
Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo.
Topics: Adjuvants, Immunologic; Animals; Antigen Presentation; Antigens, Surface; Cell Division; Cytokines; | 2001 |
Co-trimoxazole nephrotoxicity.
Topics: Acute Kidney Injury; Drug Combinations; Drug Hypersensitivity; Erythema; Humans; Kidney; Stevens-Joh | 1979 |
[Allergic-toxic agranulocytosis].
Topics: Abscess; Agranulocytosis; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Leukemia; | 1979 |
[Allergic vasculitis with arthritis due to bactrim allergy (author's transl)].
Topics: Aged; Arthritis; Blood Coagulation; Blood Platelets; Bronchitis; Drug Combinations; Drug Hypersensit | 1977 |
Stevens-Johnson syndrome (erythema multiforme) following ingestion of trimethoprim-sulfamethoxazole on two separate occasions in the same person: a case report.
Topics: Drug Combinations; Drug Hypersensitivity; Erythema Multiforme; Humans; Male; Middle Aged; Sulfametho | 1978 |
Hepatic injury in a child caused by trimethoprim-sulfamethoxazole.
Topics: Adolescent; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Combinations; Drug Hyp | 1978 |
[Generalized acute pustulosis. An unusual presentation of leukocytoclastic vasculitis].
Topics: Basement Membrane; Bronchitis; Complement C3; Drug Combinations; Drug Hypersensitivity; Female; Huma | 1978 |
[Adverse effects of treatment with sulfamethoxazole and trimethoprim. Report to the Adverse Drug Reaction Committee of the National Board of Health and Welfare].
Topics: Aged; Chemical and Drug Induced Liver Injury; Denmark; Drug Combinations; Drug Hypersensitivity; Fem | 1977 |
Letter: Reaction to trimoxazole.
Topics: Aged; Drug Combinations; Drug Hypersensitivity; Humans; Male; Sulfamethoxazole; Trimethoprim | 1976 |
[Letter: Sulfamethoxazole-trimethoprim combination (cotrimoxazole). Unusual immuno-allergic reaction].
Topics: Blood Platelet Disorders; Drug Combinations; Drug Hypersensitivity; Drug Tolerance; Female; Humans; | 1975 |
[Letter: Acute iatrogenic colitis following clindamycin and various antibiotics].
Topics: Acute Disease; Anti-Bacterial Agents; Bone Diseases; Clindamycin; Colistin; Colitis; Drug Combinatio | 1975 |
Demonstration of sensitized lymphocytes to trimethoprim/sulfamethoxazole and ofloxacin in a patient with cholestatic hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Female; Humans; O | 1992 |
Drug-induced hypothyroidism: the thyroid as a target organ in hypersensitivity reactions to anticonvulsants and sulfonamides.
Topics: Adolescent; Animals; Antibody Formation; Anticonvulsants; Cells, Cultured; Child; Child, Preschool; | 1992 |
Glutathione transferase mu deficiency is not a marker for predisposition to sulphonamide toxicity.
Topics: Adolescent; Adult; Cell Survival; Child; Child, Preschool; Disease Susceptibility; Drug Evaluation, | 1991 |
Evaluation of immune parameters in HIV+ subjects reporting adverse reactions to sulfamethoxazole.
Topics: Antigen-Antibody Complex; Drug Hypersensitivity; HIV Seropositivity; Humans; Immunoglobulin G; Sulfa | 1991 |
Allergy to sulfa drugs with postcoital urticaria.
Topics: Coitus; Drug Hypersensitivity; Female; Humans; Male; Prostatitis; Sulfamethoxazole; Trimethoprim; Ur | 1991 |
Studies of human IgE to a sulfonamide determinant.
Topics: Adolescent; Adult; Antibody Specificity; Cellulose; Child; Child, Preschool; Drug Hypersensitivity; | 1987 |
Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anti-Infective Agents; Desensitizat | 1989 |
Successful prophylaxis of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in AIDS patients with previous allergic reactions.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anti-Infective Agents; Cohort Studi | 1989 |
Reaction after re-exposure to trimethoprim-sulfamethoxazole.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Drug Hypersensitivity; Humans; Male; P | 1989 |
Therapy of pneumocystis carinii pneumonia after trimethoprim-sulfamethoxazole desensitization.
Topics: Acquired Immunodeficiency Syndrome; Adult; Combined Modality Therapy; Desensitization, Immunologic; | 1989 |
Adverse reactions to pyrimethamine-sulfadoxine in context of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Drug Hypersensitivity; Humans; Pyrimethamine; | 1985 |
Diagnosis of sulfonamide hypersensitivity reactions by in-vitro "rechallenge" with hydroxylamine metabolites.
Topics: Adult; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Female; Humans; Hydroxylamine | 1989 |
Severe hypersensitivity reaction upon rechallenge with trimethoprim-sulfamethoxazole in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Dermatitis, Exfoliative; Drug Combinations; Drug Hypersen | 1988 |
[Allergy to trimethoprim-sulfamethoxazole in normal, atopic and immunodepressed subjects].
Topics: Anti-Infective Agents; Drug Combinations; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate | 1987 |
[A case report of acquired immunodeficiency syndrome (AIDS) with hypersensitivity reactions to trimethoprim-sulfamethoxazole].
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Infective Agents; Drug Combinations; Drug Hypersensi | 1988 |
Drugs as allergens: detection and combining site specificities of IgE antibodies to sulfamethoxazole.
Topics: Adult; Aged; Allergens; Anaphylaxis; Binding, Competitive; Drug Hypersensitivity; Female; Humans; Im | 1988 |
Trimethoprim-sulfamethoxazole desensitization in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Desensitization, Immunologic; Drug Hypersensitivity; Huma | 1988 |
Malpractice claim review. Pediatrics, urology.
Topics: Child; Drug Combinations; Drug Hypersensitivity; Humans; Male; Malpractice; Sulfamethoxazole; Trimet | 1987 |
Co-trimoxazole-induced hepatic injury--an analysis of cases with hypersensitivity-like reactions.
Topics: Adult; Aged; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug | 1987 |
[Immuno-allergic reactions to cotrimoxazole in a hospital population].
Topics: Anti-Infective Agents; Complement Activation; Drug Combinations; Drug Hypersensitivity; Hospitalizat | 1987 |
An immunoassay for the detection of IgE antibodies to trimethoprim in the sera of allergic patients.
Topics: Adult; Drug Combinations; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Radioimmunoassay; | 1987 |
Oral desensitization to trimethoprim-sulfamethoxazole in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Hypersensitivity; Humans; Male; Sulfamethoxazole; Tr | 1986 |
Successful treatment of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in hypersensitive AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Diphenhydramine; Drug Combinations; Drug Hypersensitivity | 1985 |
[Cholestasis caused by co-trimoxazole. Presentation of a new patient and review of the literature].
Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Combinations; Drug Hyp | 1985 |
Precipitating antibodies to sulfathiazole in serum of patients with suspected allergy to sulfonamides.
Topics: Aged; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Immunodiffusion; Male; Middle Aged; Pre | 1974 |
[Drug monitoring in the medical ward of a regional hospital].
Topics: Adult; Ampicillin; Anticoagulants; Antidepressive Agents; Central Nervous System Stimulants; Chemica | 1972 |
[Allergic reactons and composite drugs].
Topics: Adult; Anti-Infective Agents; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; Female; Foli | 1971 |
The treatment of salmonellosis with trimethoprim-sulphamethoxazole and their combination with polymyxin B in adult patients.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Drug Combinations; Drug Hypersensitivity; Feces; Fem | 1973 |
Extended therapy with a trimethoprim-sulphonamide for the treatment of established urinary tract infection.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Drug Combinations; Drug Hypersensitivity; Escherichi | 1971 |
Adverse effects of drugs commonly used in the treatment of urinary tract infection. A report from the Australian Drug Evaluation Committee.
Topics: Ampicillin; Anti-Infective Agents, Urinary; Australia; Chloramphenicol; Drug Hypersensitivity; Human | 1972 |