sulfamethoxazole has been researched along with AIDS-Related Opportunistic Infections in 29 studies
Sulfamethoxazole: A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
sulfamethoxazole : An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
AIDS-Related Opportunistic Infections: Opportunistic infections found in patients who test positive for human immunodeficiency virus (HIV). The most common include PNEUMOCYSTIS PNEUMONIA, Kaposi's sarcoma, cryptosporidiosis, herpes simplex, toxoplasmosis, cryptococcosis, and infections with Mycobacterium avium complex, Microsporidium, and Cytomegalovirus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe a retrospective study of six HIV-positive individuals with compensated metabolic acidosis while receiving intravenous trimethoprim/sulfamethoxazole (TMP/SMX)." | 7.70 | Trimethoprim/sulfamethoxazole and metabolic acidosis in HIV-infected patients. ( Castrillón, JL; Lecumberri, JN; Porras, MC, 1998) |
| "To report a case of trimethoprim/sulfamethoxazole (TMP/SMX)-induced tremor responsive to a reduction in dosage." | 7.70 | Trimethoprim/sulfamethoxazole-induced tremor in a patient with AIDS. ( Lerner, SA; Rybak, MJ; Slavik, RS, 1998) |
| "Sulfamethoxazole (SMX) is a commonly used antibiotic for prevention of infectious diseases associated with HIV/AIDS and immune-compromised states." | 5.38 | Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients. ( Curtis, A; Koletar, SL; Papp, AC; Para, MF; Wang, D, 2012) |
| "To describe a retrospective study of six HIV-positive individuals with compensated metabolic acidosis while receiving intravenous trimethoprim/sulfamethoxazole (TMP/SMX)." | 3.70 | Trimethoprim/sulfamethoxazole and metabolic acidosis in HIV-infected patients. ( Castrillón, JL; Lecumberri, JN; Porras, MC, 1998) |
| "To report a case of trimethoprim/sulfamethoxazole (TMP/SMX)-induced tremor responsive to a reduction in dosage." | 3.70 | Trimethoprim/sulfamethoxazole-induced tremor in a patient with AIDS. ( Lerner, SA; Rybak, MJ; Slavik, RS, 1998) |
| "Trimetrexate is a powerful inhibitor of the dihydrofolate reductase of Pneumocystis carinii." | 2.67 | Trimetrexate with leucovorin versus trimethoprim-sulfamethoxazole for moderate to severe episodes of Pneumocystis carinii pneumonia in patients with AIDS: a prospective, controlled multicenter investigation of the AIDS Clinical Trials Group Protocol 029/0 ( Akil, B; Baughman, R; Boylen, CT; Davis, R; Frame, P; Hughlett, C; Nichols, L; Sattler, FR; Shelton, B; Weiss, W, 1994) |
| "We report a case of P carinii infection presenting as bilateral aural polyps, otitis media and mastoiditis in human immunodeficiency (HIV)-positive patient with no history of prior or concomitant P carinii infection." | 2.41 | Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient. ( Elmahallawy, M; Horsfield, C; Praveen, CV; Terry, RM, 2002) |
| "Sulfamethoxazole (SMX) is a commonly used antibiotic for prevention of infectious diseases associated with HIV/AIDS and immune-compromised states." | 1.38 | Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients. ( Curtis, A; Koletar, SL; Papp, AC; Para, MF; Wang, D, 2012) |
| "Nine patients had cervical lymphadenitis; 2 had disseminated infection." | 1.31 | Clinical and pathologic features of Mycobacterium fortuitum infections. An emerging pathogen in patients with AIDS. ( Boyars, MC; Schnadig, VJ; Smith, MB; Woods, GL, 2001) |
| "aureus bacteremia were compared against 188 controls selected from patients with CD4 cell counts < 200 x 10(6)/l." | 1.30 | Prior antimicrobials and staphylococcal bacteremia in HIV-infected patients. ( Chaisson, RE; Moore, RD; Styrt, BA, 1997) |
| " Ro 11-8958, TMP, and diaveridine used at a dosage of 20 mg/kg/day with SMX were only slightly more effective than SMX used alone." | 1.29 | Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis. ( Foy, J; Steele, P; Walzer, PD; White, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 17 (58.62) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 2 (6.90) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Vidal, JE | 1 |
| Cunha, MA | 1 |
| Kassab, MJ | 1 |
| Dauar, RF | 1 |
| Vasconcelos, DM | 1 |
| Li, Y | 1 |
| Zeng, YM | 1 |
| Lu, YQ | 1 |
| Qin, YY | 1 |
| Chen, YK | 1 |
| Cho, JY | 1 |
| Kim, DM | 1 |
| Kwon, YE | 1 |
| Yoon, SH | 1 |
| Lee, SI | 1 |
| Francesconi, F | 1 |
| Rocha, MA | 1 |
| Bonilla, LF | 1 |
| da Silva, LA | 1 |
| Francesconi, VA | 1 |
| Thomas, M | 1 |
| Rupali, P | 1 |
| Woodhouse, A | 1 |
| Ellis-Pegler, R | 1 |
| Goussard, P | 1 |
| Kling, S | 1 |
| Gie, RP | 1 |
| Nel, ED | 1 |
| Heyns, L | 1 |
| Rossouw, GJ | 1 |
| Janson, JT | 1 |
| Wang, D | 1 |
| Curtis, A | 1 |
| Papp, AC | 1 |
| Koletar, SL | 1 |
| Para, MF | 1 |
| Rodriguez, M | 1 |
| Fishman, JA | 1 |
| Crone, KG | 1 |
| Muraski, MB | 1 |
| Skeel, JD | 1 |
| Love-Gregory, L | 1 |
| Ladenson, JH | 1 |
| Gronowski, AM | 1 |
| Raszka, WV | 1 |
| Skillman, LP | 1 |
| McEvoy, PL | 1 |
| Alder, J | 1 |
| Hutch, T | 1 |
| Meulbroek, JA | 1 |
| Clement, JC | 1 |
| Sattler, FR | 1 |
| Frame, P | 1 |
| Davis, R | 1 |
| Nichols, L | 1 |
| Shelton, B | 1 |
| Akil, B | 1 |
| Baughman, R | 1 |
| Hughlett, C | 1 |
| Weiss, W | 1 |
| Boylen, CT | 1 |
| Lee, BL | 1 |
| Delahunty, T | 1 |
| Safrin, S | 1 |
| Hale, E | 1 |
| Habte-Gabr, E | 1 |
| McQueen, R | 1 |
| Gordon, R | 1 |
| Walzer, PD | 1 |
| Foy, J | 1 |
| Steele, P | 1 |
| White, M | 1 |
| Martinez, M | 1 |
| Soriano, V | 1 |
| González-Lahoz, J | 1 |
| Kaplan, JE | 1 |
| Hu, DJ | 1 |
| Holmes, KK | 1 |
| Jaffe, HW | 1 |
| Masur, H | 1 |
| De Cock, KM | 1 |
| Tumbarello, M | 1 |
| Tacconelli, E | 1 |
| Cauda, R | 1 |
| Ortona, L | 1 |
| Styrt, BA | 1 |
| Chaisson, RE | 2 |
| Moore, RD | 2 |
| Bernard, E | 1 |
| Delgiudice, P | 1 |
| Carles, M | 1 |
| Boissy, C | 1 |
| Saint-Paul, MC | 1 |
| Le Fichoux, Y | 1 |
| Michiels, JF | 1 |
| Dellamonica, P | 1 |
| Porras, MC | 1 |
| Lecumberri, JN | 1 |
| Castrillón, JL | 1 |
| Slavik, RS | 1 |
| Rybak, MJ | 1 |
| Lerner, SA | 1 |
| Eldred, LJ | 1 |
| Wu, AW | 1 |
| al-Tawfiq, JA | 1 |
| Sorensen, SJ | 1 |
| Cushing, HE | 1 |
| Meshnick, SR | 1 |
| Helweg-Larsen, J | 1 |
| Benfield, TL | 1 |
| Eugen-Olsen, J | 1 |
| Lundgren, JD | 1 |
| Lundgren, B | 1 |
| Asencio Marchante, R | 1 |
| Lissen Otero, E | 1 |
| Smith, MB | 1 |
| Schnadig, VJ | 1 |
| Boyars, MC | 1 |
| Woods, GL | 1 |
| Praveen, CV | 1 |
| Terry, RM | 1 |
| Elmahallawy, M | 1 |
| Horsfield, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Comparative, Double-Blind Trial of Trimetrexate (CI-898) With Leucovorin Calcium Rescue Versus Trimethoprim / Sulfamethoxazole for Moderately Severe Pneumocystis Carinii Pneumonia in Patients With AIDS[NCT00001014] | Phase 3 | 302 participants | Interventional | Completed | |||
| A Randomized, Comparative, Double-Blind Trial of Trimetrexate (CI-898) With Leucovorin Calcium Rescue Versus Trimethoprim / Sulfamethoxazole for Moderately Severe Pneumocystis Carinii Pneumonia in Patients With AIDS[NCT00001013] | Phase 3 | 364 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for sulfamethoxazole and AIDS-Related Opportunistic Infections
| Article | Year |
|---|---|
Prevention of infection due to Pneumocystis spp. in human immunodeficiency virus-negative immunocompromised patients.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Bone Marrow Transplantation; Humans; Immun | 2004 |
Preventing opportunistic infections in human immunodeficiency virus-infected persons: implications for the developing world.
Topics: Africa; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antitubercular Agents; Asia; B | 1996 |
Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Dapsone; Ear Neoplasms; Ear, Middle | 2002 |
5 trials available for sulfamethoxazole and AIDS-Related Opportunistic Infections
21 other studies available for sulfamethoxazole and AIDS-Related Opportunistic Infections
| Article | Year |
|---|---|
First case report of eosinophilic meningitis associated with cerebral toxoplasmosis in an HIV-positive patient.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Anti-Inflammatory Agents; Brain | 2020 |
Newly formed cystic lesions for the development of pneumomediastinum in Pneumocystis jirovecii pneumonia.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Humans; Male; Mediastinal Emphy | 2009 |
A rapidly growing lesion on the lip--quiz case.
Topics: Adult; AIDS-Related Opportunistic Infections; Biopsy, Needle; Disease Progression; Drug Therapy, Com | 2009 |
Good outcome with trimethoprim 10 mg/kg/day-sulfamethoxazole 50 mg/kg/day for Pneumocystis jirovecii pneumonia in HIV infected patients.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Female; HIV Infections; H | 2009 |
Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Catalytic Domain; Female; Genot | 2012 |
Between a rock and a hard place: disclosing medical errors.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Fatal Outcome; Female; Humans; | 2006 |
In vitro susceptibility of clinical isolates of Mycobacterium avium and M. intracellulare to folate antagonists.
Topics: Adult; Aged; Aged, 80 and over; AIDS-Related Opportunistic Infections; Child; Child, Preschool; Drug | 1994 |
Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine.
Topics: AIDS-Related Opportunistic Infections; Animals; Clarithromycin; Disease Models, Animal; Dose-Respons | 1994 |
Co-trimoxazole for the treatment of listeriosis and its successful use in a patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Humans; Listeria monocytogenes; Listeriosis; Male; Sul | 1994 |
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis.
Topics: AIDS-Related Opportunistic Infections; Animals; Dapsone; Disease Models, Animal; Dose-Response Relat | 1993 |
Secondary Pneumocystis carinii pneumonia prophylaxis with trimethoprim-sulphamethoxazole does not prevent bacterial pneumonia in HIV-infected persons.
Topics: Adult; AIDS-Related Opportunistic Infections; Case-Control Studies; Drug Therapy, Combination; Human | 1996 |
Prior antimicrobials and staphylococcal bacteremia in HIV-infected patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Bacteremia; Case-Control Studie | 1997 |
Disseminated isosporiasis in an AIDS patient.
Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Anti-Infective Agents; Coccidiosis; Female; H | 1997 |
Trimethoprim/sulfamethoxazole and metabolic acidosis in HIV-infected patients.
Topics: Acidosis; Adult; Aged; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Female; Humans; | 1998 |
Trimethoprim/sulfamethoxazole-induced tremor in a patient with AIDS.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Humans; Male; Middle Aged; Pneumonia, | 1998 |
Adherence to antiretroviral and pneumocystis prophylaxis in HIV disease.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Anti-Infective Agents; An | 1998 |
Therapeutic failure of trimethoprim/sulfamethoxazole in the treatment of Pneumocystis carinii pneumonia.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Drug Combinations; Humans; Male; Middl | 1999 |
Drug-resistant Pneumocystis carinii.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Dihydropteroate Synthase; Dru | 1999 |
Effects of mutations in Pneumocystis carinii dihydropteroate synthase gene on outcome of AIDS-associated P. carinii pneumonia.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Bronchoalveolar Lavage Fluid; Cohort Studies; Di | 1999 |
[Secondary prevention of opportunistic infections in HIV-infected patients].
Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal A | 2001 |
Clinical and pathologic features of Mycobacterium fortuitum infections. An emerging pathogen in patients with AIDS.
Topics: Abscess; Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Biopsy, N | 2001 |