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sulfamethizole and Chemical and Drug Induced Liver Injury

sulfamethizole has been researched along with Chemical and Drug Induced Liver Injury in 13 studies

Sulfamethizole: A sulfathiazole antibacterial agent.
sulfamethizole : A sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2.

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems."1.36Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's1 (7.69)18.2507
2000's0 (0.00)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Greene, N1
Fisk, L1
Naven, RT1
Note, RR1
Patel, ML1
Pelletier, DJ1
Ekins, S1
Williams, AJ1
Xu, JJ1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Warner, DJ1
Chen, H1
Cantin, LD1
Kenna, JG1
Stahl, S1
Walker, CL1
Noeske, T1
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
HUSEBYE, KO1
Jørgensen, G1
Iwarson, S1
Lundin, P1
Tönder, M1
Nordöy, A1
Elgjo, K1
Konttinen, A3
Peräsalo, JO1
Eisalo, A1
Peräsalo, J1

Reviews

1 review available for sulfamethizole and Chemical and Drug Induced Liver Injury

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Other Studies

12 other studies available for sulfamethizole and Chemical and Drug Induced Liver Injury

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
JAUNDICE WITH PERSISTING PERICHOLANGIOLITIC INFLAMMATION IN A PATIENT TREATED WITH CHLOROTHIAZIDE. REPORT OF A CASE.
    The American journal of digestive diseases, 1964, Volume: 9

    Topics: Biopsy; Cerebral Hemorrhage; Chemical and Drug Induced Liver Injury; Chlorothiazide; Coronary Diseas

1964
[Effects of drugs on the liver. A review illustrated with 3 clinical cases].
    Ugeskrift for laeger, 1994, Jan-10, Volume: 156, Issue:2

    Topics: Acetaminophen; Adult; Aged; Androgens; Chemical and Drug Induced Liver Injury; Denmark; Disulfiram;

1994
Multiple attacks of jaundice associated with repeated sulfonamide treatment.
    Acta medica Scandinavica, 1979, Volume: 206, Issue:3

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Liver; Liver

1979
Sulfonamide-induced chronic liver disease.
    Scandinavian journal of gastroenterology, 1974, Volume: 9, Issue:1

    Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Follow-Up Studies; Humans;

1974
Hepatotoxicity of sulphamethoxyridazine.
    British medical journal, 1972, Apr-15, Volume: 2, Issue:5806

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Co

1972
Sulfonamide hepatitis.
    Acta medica Scandinavica, 1972, Volume: 191, Issue:5

    Topics: Aged; Aniline Compounds; Bilirubin; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans;

1972
[Sulfonamide hepatitis].
    Duodecim; laaketieteellinen aikakauskirja, 1971, Volume: 87, Issue:22

    Topics: Administration, Oral; Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Middle Ag

1971