sulfamethazine has been researched along with Thyroid Neoplasms in 4 studies
Sulfamethazine: A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
sulfamethazine : A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position.
Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These questions center on the suitability of the rodent model for agents that exert their toxic effects via specific enzyme interactions and endocrine mechanisms which appear to be inoperative within humans." | 2.40 | An FDA review of sulfamethazine toxicity. ( Casciano, DA; Doerge, DR; Gaylor, DW; Kadlubar, FF; Lorentzen, RJ; Miller, MA; Poirier, LA; Schwetz, BA, 1999) |
| " No difference in feed consumption was found between the control and dosed rats." | 1.28 | Chronic toxicity/carcinogenicity studies of sulphamethazine in Fischer 344/N rats: two-generation exposure. ( Allen, R; Gaylor, DW; Littlefield, NA; Sheldon, WG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McClain, RM | 1 |
| Poirier, LA | 1 |
| Doerge, DR | 1 |
| Gaylor, DW | 3 |
| Miller, MA | 1 |
| Lorentzen, RJ | 1 |
| Casciano, DA | 1 |
| Kadlubar, FF | 1 |
| Schwetz, BA | 1 |
| Littlefield, NA | 2 |
| Sheldon, WG | 1 |
| Allen, R | 1 |
| Blackwell, BN | 1 |
| Allen, RR | 1 |
2 reviews available for sulfamethazine and Thyroid Neoplasms
| Article | Year |
|---|---|
Mechanistic considerations for the relevance of animal data on thyroid neoplasia to human risk assessment.
Topics: Animals; Humans; Risk Assessment; Species Specificity; Sulfamethazine; Thyroid Gland; Thyroid Hormon | 1995 |
An FDA review of sulfamethazine toxicity.
Topics: Animals; Anti-Infective Agents; Carcinogenicity Tests; Carcinogens; Humans; Sulfamethazine; Thyroid | 1999 |
2 other studies available for sulfamethazine and Thyroid Neoplasms
| Article | Year |
|---|---|
Chronic toxicity/carcinogenicity studies of sulphamethazine in Fischer 344/N rats: two-generation exposure.
Topics: Adenocarcinoma; Adenoma; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Dose-Response Rel | 1990 |
Chronic toxicity/carcinogenicity studies of sulphamethazine in B6C3F1 mice.
Topics: Adenoma; Animals; Body Weight; Carcinogens; Diet; Dose-Response Relationship, Drug; Eating; Female; | 1989 |