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sulfamethazine and Thyroid Neoplasms

sulfamethazine has been researched along with Thyroid Neoplasms in 4 studies

Sulfamethazine: A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
sulfamethazine : A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position.

Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.

Research Excerpts

ExcerptRelevanceReference
" These questions center on the suitability of the rodent model for agents that exert their toxic effects via specific enzyme interactions and endocrine mechanisms which appear to be inoperative within humans."2.40An FDA review of sulfamethazine toxicity. ( Casciano, DA; Doerge, DR; Gaylor, DW; Kadlubar, FF; Lorentzen, RJ; Miller, MA; Poirier, LA; Schwetz, BA, 1999)
" No difference in feed consumption was found between the control and dosed rats."1.28Chronic toxicity/carcinogenicity studies of sulphamethazine in Fischer 344/N rats: two-generation exposure. ( Allen, R; Gaylor, DW; Littlefield, NA; Sheldon, WG, 1990)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McClain, RM1
Poirier, LA1
Doerge, DR1
Gaylor, DW3
Miller, MA1
Lorentzen, RJ1
Casciano, DA1
Kadlubar, FF1
Schwetz, BA1
Littlefield, NA2
Sheldon, WG1
Allen, R1
Blackwell, BN1
Allen, RR1

Reviews

2 reviews available for sulfamethazine and Thyroid Neoplasms

ArticleYear
Mechanistic considerations for the relevance of animal data on thyroid neoplasia to human risk assessment.
    Mutation research, 1995, Volume: 333, Issue:1-2

    Topics: Animals; Humans; Risk Assessment; Species Specificity; Sulfamethazine; Thyroid Gland; Thyroid Hormon

1995
An FDA review of sulfamethazine toxicity.
    Regulatory toxicology and pharmacology : RTP, 1999, Volume: 30, Issue:3

    Topics: Animals; Anti-Infective Agents; Carcinogenicity Tests; Carcinogens; Humans; Sulfamethazine; Thyroid

1999

Other Studies

2 other studies available for sulfamethazine and Thyroid Neoplasms

ArticleYear
Chronic toxicity/carcinogenicity studies of sulphamethazine in Fischer 344/N rats: two-generation exposure.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1990, Volume: 28, Issue:3

    Topics: Adenocarcinoma; Adenoma; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Dose-Response Rel

1990
Chronic toxicity/carcinogenicity studies of sulphamethazine in B6C3F1 mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1989, Volume: 27, Issue:7

    Topics: Adenoma; Animals; Body Weight; Carcinogens; Diet; Dose-Response Relationship, Drug; Eating; Female;

1989