sulfamethazine has been researched along with Hyperplasia in 4 studies
Sulfamethazine: A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
sulfamethazine : A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " No difference in feed consumption was found between the control and dosed rats." | 1.28 | Chronic toxicity/carcinogenicity studies of sulphamethazine in Fischer 344/N rats: two-generation exposure. ( Allen, R; Gaylor, DW; Littlefield, NA; Sheldon, WG, 1990) |
| " Thyroid gland enlargement was evident at necropsy in one half of the rats (12 of 24) which received the 3600 ppm dosage level of sulfamethazine and in 1 of 24 rats fed the 2400 ppm level." | 1.27 | Effect of subchronic oral sulfamethazine administration on Fischer 344 rats and B6C3F1 mice. ( Heath, JE; Littlefield, NA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heath, JE | 2 |
| Littlefield, NA | 4 |
| Sheldon, WG | 1 |
| Allen, R | 1 |
| Gaylor, DW | 2 |
| Blackwell, BN | 1 |
| Allen, RR | 1 |
4 other studies available for sulfamethazine and Hyperplasia
| Article | Year |
|---|---|
Morphological effects of subchronic oral sulfamethazine administration on Fischer 344 rats and B6C3F1 mice.
Topics: Administration, Oral; Animals; Female; Hyperplasia; Male; Mice; Microscopy, Electron; Rats; Rats, In | 1984 |
Effect of subchronic oral sulfamethazine administration on Fischer 344 rats and B6C3F1 mice.
Topics: Administration, Oral; Animals; Female; Hyperplasia; Male; Mice; Rats; Rats, Inbred F344; Sulfamethaz | 1984 |
Chronic toxicity/carcinogenicity studies of sulphamethazine in Fischer 344/N rats: two-generation exposure.
Topics: Adenocarcinoma; Adenoma; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Dose-Response Rel | 1990 |
Chronic toxicity/carcinogenicity studies of sulphamethazine in B6C3F1 mice.
Topics: Adenoma; Animals; Body Weight; Carcinogens; Diet; Dose-Response Relationship, Drug; Eating; Female; | 1989 |