sulfamethazine has been researched along with Aging in 9 studies
Sulfamethazine: A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
sulfamethazine : A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetylator phenotypes were determined with sulfamethazine in 114 healthy volunteers, 87 patients with immunogenic hyperthyroidism (Graves' disease) and 38 patients with disseminated thyroid autonomies." | 3.67 | N-acetylator phenotypes in hyperthyroidism. ( Franke, G; Gothe, P; Meng, S; Meng, W; Siegmund, W, 1988) |
| " Differences were found between one-three-weeks-old calves and seven-fifteen-weeks-old calves, in pharmacokinetic parameters (clearance, area under the concentration-time curve and elimination half-life) and in the PK/PD integration." | 2.73 | Effects of age on the pharmacokinetics of single dose sulfamethazine after intravenous administration in cattle. ( Baroni, EE; Boggio, JC; Díaz, DC; Picco, E; Rodríguez, C; San Andrés, MI; Waxman, S, 2008) |
| " The inducer dose of 150 mg SMZ/kg and the inhibitory dose of 300 mg SMZ/kg were selected for dosing young male, old male and adult female rats." | 1.30 | In vivo and in vitro effect of sulfamethazine on hepatic mixed function oxidases in rats. ( Govindwar, SP; Kodam, KM, 1997) |
| "In 41 patients aged 3-15 y with phenylketonuria, the acetylation indices showed a significantly higher proportion of fast acetylators - 24 (58." | 1.28 | N-acetylation in healthy and diseased children. ( Brysová, V; Hadasová, E; Kadlcáková, E, 1990) |
| "Plasma disposition, protein binding, urinary recovery, and renal clearance of sulfamethazine (SMZ), its N4-acetylsulfamethazine (N4-SMZ), and its 2 hydroxy metabolites--6-hydroxymethylsulfamethazine (SCH2OH) and 5-hydroxysulfamethazine (SOL)--and the glucuronide of the latter were studied in 7 cows and 7 calves to determine the relationship between these values and the age of the animal and dosage applied." | 1.27 | Age and dosage dependency in the plasma disposition and the renal clearance of sulfamethazine and its N4-acetyl and hydroxy metabolites in calves and cows. ( Baakman, M; Breukink, HJ; Driessens, F; Mevius, D; Nouws, JF; Vree, TB, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuenzel, WJ | 1 |
| Baroni, EE | 1 |
| Díaz, DC | 1 |
| Picco, E | 1 |
| Waxman, S | 1 |
| Rodríguez, C | 1 |
| San Andrés, MI | 1 |
| Boggio, JC | 1 |
| Gachályi, B | 1 |
| Vas, A | 1 |
| Hajós, P | 1 |
| Káldor, A | 1 |
| Gupta, RC | 1 |
| Nair, CR | 1 |
| Jindal, SK | 1 |
| Malik, SK | 1 |
| Kodam, KM | 1 |
| Govindwar, SP | 1 |
| Hadasová, E | 1 |
| Brysová, V | 1 |
| Kadlcáková, E | 1 |
| Siegmund, W | 1 |
| Franke, G | 1 |
| Meng, S | 1 |
| Gothe, P | 1 |
| Meng, W | 1 |
| Nouws, JF | 1 |
| Vree, TB | 1 |
| Baakman, M | 1 |
| Driessens, F | 1 |
| Breukink, HJ | 1 |
| Mevius, D | 1 |
| Pontiroli, AE | 1 |
| De Pasqua, A | 1 |
| Bonisolli, L | 1 |
| Pozza, G | 1 |
1 trial available for sulfamethazine and Aging
| Article | Year |
|---|---|
Effects of age on the pharmacokinetics of single dose sulfamethazine after intravenous administration in cattle.
Topics: Aging; Animals; Anti-Bacterial Agents; Area Under Curve; Cattle; Dose-Response Relationship, Drug; F | 2008 |
8 other studies available for sulfamethazine and Aging
| Article | Year |
|---|---|
A landmark contribution to poultry science--a possible mode of action of sulfamethazine on the reproductive system of Leghorn cockerels.
Topics: Aging; Animals; Anti-Bacterial Agents; Chickens; History, 20th Century; Male; Publishing; Sulfametha | 2009 |
Acetylator phenotypes: effect of age.
Topics: Acetylation; Adult; Aged; Aging; Chemistry, Organic; Female; Humans; Hungary; Kinetics; Male; Middle | 1984 |
Incidence of isoniazid acetylation phenotypes in North Indians.
Topics: Acetylation; Adult; Aging; Alcohol Drinking; Female; Humans; India; Isoniazid; Kinetics; Male; Middl | 1984 |
In vivo and in vitro effect of sulfamethazine on hepatic mixed function oxidases in rats.
Topics: Aging; Aminopyrine N-Demethylase; Animals; Anti-Infective Agents; Dose-Response Relationship, Drug; | 1997 |
N-acetylation in healthy and diseased children.
Topics: Acetylation; Adolescent; Aging; Child; Child, Preschool; Czechoslovakia; Diabetes Mellitus, Type 1; | 1990 |
N-acetylator phenotypes in hyperthyroidism.
Topics: Acetylation; Adult; Aged; Aging; Female; Humans; Hyperthyroidism; Male; Middle Aged; Phenotype; Sulf | 1988 |
Age and dosage dependency in the plasma disposition and the renal clearance of sulfamethazine and its N4-acetyl and hydroxy metabolites in calves and cows.
Topics: Aging; Animals; Cattle; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Fema | 1986 |
Ageing and acetylator phenotype as determined by administration of sulphadimidine.
Topics: Acetylation; Adolescent; Adult; Aged; Aging; Humans; Middle Aged; Phenotype; Sulfamethazine | 1985 |