sulfadimethoxine has been researched along with Thyroid Neoplasms in 16 studies
Sulfadimethoxine: A sulfanilamide that is used as an anti-infective agent.
sulfadimethoxine : A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position.
Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have shown phosphoinositide 3-kinase (PI3K)/Akt signaling activation in thyroid capsular invasive carcinomas (CICs), which are highly induced by promotion with sulfadimethoxine (SDM) in a rat 2-stage thyroid carcinogenesis model." | 7.77 | Preventive effects of calcitriol on the development of capsular invasive carcinomas in a rat two-stage thyroid carcinogenesis model. ( Fujimoto, H; Hirose, M; Kemmochi, S; Mitsumori, K; Nishikawa, A; Shibutani, M; Woo, GH, 2011) |
| "We previously demonstrated that thyroid capsular inflammation induced by continuous treatment with the antithyroidal agent sulfadimethoxine is associated with development of invasive follicular cell carcinomas in rats initiated with N-bis(2-hydroxypropyl)nitrosamine (DHPN)." | 7.74 | Depression of T cell-mediated immunity reduces sulfadimethoxine-induced capsular inflammation and inhibits associated development of invasive thyroid follicular cell carcinomas in rats. ( Cho, YM; Hasumura, M; Hirose, M; Imai, T; Onose, J, 2007) |
| "We have shown phosphoinositide 3-kinase (PI3K)/Akt signaling activation in thyroid capsular invasive carcinomas (CICs), which are highly induced by promotion with sulfadimethoxine (SDM) in a rat 2-stage thyroid carcinogenesis model." | 3.77 | Preventive effects of calcitriol on the development of capsular invasive carcinomas in a rat two-stage thyroid carcinogenesis model. ( Fujimoto, H; Hirose, M; Kemmochi, S; Mitsumori, K; Nishikawa, A; Shibutani, M; Woo, GH, 2011) |
| "We have reported that thyroid capsular thickening with inflammation induced by an antithyroidal agent, sulfadimethoxine (SDM), might play a role in the development of invasive follicular carcinomas in rats initiated with N-bis(2-hydroxypropyl)nitrosamine (DHPN)." | 3.75 | Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation. ( Cho, YM; Hasumura, M; Hirose, M; Imai, T; Nishikawa, A; Ota, Y; Takami, S, 2009) |
| "We previously demonstrated that thyroid capsular inflammation induced by continuous treatment with the antithyroidal agent sulfadimethoxine is associated with development of invasive follicular cell carcinomas in rats initiated with N-bis(2-hydroxypropyl)nitrosamine (DHPN)." | 3.74 | Depression of T cell-mediated immunity reduces sulfadimethoxine-induced capsular inflammation and inhibits associated development of invasive thyroid follicular cell carcinomas in rats. ( Cho, YM; Hasumura, M; Hirose, M; Imai, T; Onose, J, 2007) |
| "We have previously reported that thyroid capsular inflammation induced by sulfadimethoxine (SDM), a goitrogen, might play a role in development of invasive follicular cell adenocarcinomas in rats initiated with N-bis(2-hydroxypropyl)nitrosamine (DHPN)." | 3.73 | Development of invasive follicular cell carcinomas in a rat thyroid carcinogenesis model: biological impact of capsular inflammation and reduced cyclooxygenase-2 expression. ( Cho, YM; Hasumura, M; Hirose, M; Imai, T; Onose, J; Takizawa, T; Ueda, M, 2005) |
| " injection) were examined following chronic administration of 0." | 1.29 | Effect of thyroid stimulating hormone on the development and progression of rat thyroid follicular cell tumors. ( Hayashi, Y; Kitaura, K; Mitsumori, K; Onodera, H; Shimo, T; Takahashi, M; Yasuhara, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 8 (50.00) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woo, GH | 3 |
| Takahashi, M | 8 |
| Inoue, K | 2 |
| Fujimoto, H | 3 |
| Igarashi, K | 1 |
| Kanno, J | 1 |
| Hirose, M | 10 |
| Nishikawa, A | 7 |
| Shibutani, M | 5 |
| Imai, T | 4 |
| Hasumura, M | 4 |
| Cho, YM | 4 |
| Ota, Y | 2 |
| Takami, S | 2 |
| Hoshi, S | 1 |
| Hoshi, N | 1 |
| Okamoto, M | 1 |
| Paiz, J | 1 |
| Kusakabe, T | 1 |
| Ward, JM | 1 |
| Kimura, S | 2 |
| Kemmochi, S | 4 |
| Mitsumori, K | 8 |
| Oyamada, T | 1 |
| Ogawa, K | 1 |
| Shimamoto, K | 2 |
| Shiraki, A | 1 |
| Onda, N | 2 |
| Hasumi, K | 2 |
| Suzuki, K | 2 |
| Yamamichi, S | 1 |
| Onose, J | 2 |
| Ueda, M | 1 |
| Takizawa, T | 1 |
| Onodera, H | 4 |
| Shimo, T | 3 |
| Yasuhara, K | 3 |
| Kitaura, K | 2 |
| Hayashi, Y | 2 |
| Ueno, Y | 1 |
| Katayama, J | 1 |
| Saito, A | 1 |
| Son, HY | 2 |
| Ikeda, T | 2 |
| Nakamura, H | 2 |
| Miyauchi, M | 2 |
| Imazawa, T | 2 |
| Furukawa, F | 1 |
| Takagi, H | 1 |
| Nasu, M | 1 |
| Tamura, T | 1 |
| Takegawa, K | 1 |
16 other studies available for sulfadimethoxine and Thyroid Neoplasms
| Article | Year |
|---|---|
Cellular distributions of molecules with altered expression specific to thyroid proliferative lesions developing in a rat thyroid carcinogenesis model.
Topics: Adenoma; Animals; Cadherins; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Ceruloplasmin | 2009 |
Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation.
Topics: Adenocarcinoma, Follicular; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Progressi | 2009 |
Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice.
Topics: Adenoma; Amitrole; Animals; Carcinogens; Female; Genes, ras; Hyperplasia; Male; Mice; Nitrosamines; | 2009 |
Involvement of PTEN/Akt signaling in capsular invasive carcinomas developed in a rat two-stage thyroid carcinogenesis model after promotion with sulfadimethoxine.
Topics: Animals; Cell Proliferation; Immunohistochemistry; Male; Neoplasm Invasiveness; Proto-Oncogene Prote | 2011 |
Preventive effects of calcitriol on the development of capsular invasive carcinomas in a rat two-stage thyroid carcinogenesis model.
Topics: Animals; Apoptosis; Body Weight; Calcitriol; Calcium Channel Agonists; Carcinoma; Male; Phosphatidyl | 2011 |
Prostaglandin synthases influence thyroid follicular cell proliferation but not carcinogenesis in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.
Topics: Adenocarcinoma, Follicular; Animals; Antithyroid Agents; Cell Proliferation; Cyclooxygenase 2; Cyclo | 2012 |
Promoting effects of carminic acid-enriched cochineal extracts on capsular invasive thyroid carcinomas through targeting activation of angiogenesis in rats.
Topics: Angiogenesis Inducing Agents; Animals; Carmine; Disease Models, Animal; Drinking Water; Hypoxia-Indu | 2012 |
Lac color inhibits development of rat thyroid carcinomas through targeting activation of plasma hyaluronan-binding protein.
Topics: Animals; Azo Compounds; Carcinoma, Papillary, Follicular; Cell Proliferation; Disease Models, Animal | 2012 |
Development of invasive follicular cell carcinomas in a rat thyroid carcinogenesis model: biological impact of capsular inflammation and reduced cyclooxygenase-2 expression.
Topics: Adenocarcinoma, Follicular; Animals; Anti-Infective Agents; Antithyroid Agents; Blotting, Western; C | 2005 |
Depression of T cell-mediated immunity reduces sulfadimethoxine-induced capsular inflammation and inhibits associated development of invasive thyroid follicular cell carcinomas in rats.
Topics: Adenocarcinoma, Follicular; Administration, Oral; Animals; Immunity, Cellular; Immunohistochemistry; | 2007 |
Thyroid proliferative lesions induced by anti-thyroid drugs in rats are not always accompanied by sustained increases in serum TSH.
Topics: Animals; Antithyroid Agents; Male; Nitrosamines; Rats; Rats, Inbred F344; Sulfadimethoxine; Thiourea | 1994 |
Effect of rat thyroid proliferative lesion development by intermittent treatment with sulfadimethoxine.
Topics: Animals; Carcinogens; Drug Administration Schedule; Endoplasmic Reticulum, Rough; Hyperplasia; Male; | 1995 |
Effect of thyroid stimulating hormone on the development and progression of rat thyroid follicular cell tumors.
Topics: Animals; Carcinogens; Cell Division; Disease Progression; Goiter; Hyperplasia; Male; Nitrosamines; O | 1995 |
Lack of modifying effects of environmental estrogenic compounds on the development of thyroid proliferative lesions in male rats pretreated with N-bis(2-hydroxypropyl)nitrosamine (DHPN).
Topics: Animals; Body Weight; Furans; Genistein; Glycine max; Male; Nitrosamines; Organ Size; Phenols; Rats; | 2000 |
Synergistic effects of high-dose soybean intake with iodine deficiency, but not sulfadimethoxine or phenobarbital, on rat thyroid proliferation.
Topics: Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Female; Glycine max; Hyper | 2001 |
Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats.
Topics: Adenoma; Animals; Benzhydryl Compounds; Body Weight; Carcinogens; Cholesterol; Disease Models, Anima | 2002 |