sulfadimethoxine has been researched along with Jaundice in 13 studies
Sulfadimethoxine: A sulfanilamide that is used as an anti-infective agent.
sulfadimethoxine : A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position.
Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acute brainstem auditory evoked potential (BAEP) abnormalities occur after giving sulfadimethoxine to 16-day-old jaundiced Gunn rats to displace bilirubin into tissue including brain." | 7.74 | Minocycline blocks acute bilirubin-induced neurological dysfunction in jaundiced Gunn rats. ( Geiger, AS; Rice, AC; Shapiro, SM, 2007) |
| "Bilirubin content was analyzed by high-performance liquid chromatography and Cyp1a1, 1a2, and 2a3 mRNA expression was analyzed by quantitative PCR (qPCR) in cortex (Cx), cerebellum (Cll), superior colliculi (SC), and inferior colliculi (IC) of 17-d-old hyperbilirubinemic (jj) Gunn rat pups before and after administration of sulphadimethoxine to acutely displace bilirubin from plasma albumin." | 5.38 | Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups. ( Berengeno, AL; Gazzin, S; Giraudi, PJ; Konickova, R; Raseni, A; Robert, MC; Tiribelli, C; Vitek, L; Zabetta, CC; Zdrahalova, L; Zelenka, J, 2012) |
| "Spontaneously jaundiced Gunn rats exposed to sulfadimethoxine develop bilirubin encephalopathy (kernicterus) with hearing loss and dystonia, closely resembling the human syndrome." | 3.75 | Quantification of gait in dystonic Gunn rats. ( Baron, MS; Chaniary, KD; Ramakrishnan, V; Rice, AC; Shapiro, SM; Wetzel, PA, 2009) |
| " Acute brainstem auditory evoked potential (BAEP) abnormalities occur after giving sulfadimethoxine to 16-day-old jaundiced Gunn rats to displace bilirubin into tissue including brain." | 3.74 | Minocycline blocks acute bilirubin-induced neurological dysfunction in jaundiced Gunn rats. ( Geiger, AS; Rice, AC; Shapiro, SM, 2007) |
| "Bilirubin encephalopathy or kernicterus is a potentially serious complication of neonatal hyperbilirubinemia." | 3.74 | NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity. ( Geiger, A; Rice, AC; Shapiro, SM; Sombati, S, 2007) |
| "At 15 days of age, jj and nonjaundiced (Nj) littermates were injected with sulfadimethoxine (sulfa) and killed 3 days later by transcardial perfusion." | 3.73 | The jaundiced gunn rat model of auditory neuropathy/dyssynchrony. ( Shaia, WT; Shapiro, SM; Spencer, RF, 2005) |
| " We calculated in vivo CNS B(F) levels in Gunn rat pups (15-19 d old; heterozygous nonjaundiced Gunn rats (J/j) and homozygous jaundiced Gunn rats (j/j); saline or sulfadimethoxine treated) based on 1) total brain bilirubin (TBB) content, 2) brain albumin level, 3) CNS bilirubin binding capacity attributable to brain albumin determined using an ultrafiltration technique, and 4) published Gunn rat albumin-bilirubin binding constants (k)." | 3.73 | Calculated in vivo free bilirubin levels in the central nervous system of Gunn rat pups. ( Daood, MJ; Watchko, JF, 2006) |
| " Abnormal BAEP occur in jaundiced Gunn rats after injection of sulfadimethoxine (sulfa) 100 mg/kg intraperitoneally, which displaces bilirubin from blood albumin binding sites and promotes the net transfer of bilirubin into brain tissue." | 3.68 | Reversible brainstem auditory evoked potential abnormalities in jaundiced Gunn rats given sulfonamide. ( Shapiro, SM, 1993) |
| "Bilirubin content was analyzed by high-performance liquid chromatography and Cyp1a1, 1a2, and 2a3 mRNA expression was analyzed by quantitative PCR (qPCR) in cortex (Cx), cerebellum (Cll), superior colliculi (SC), and inferior colliculi (IC) of 17-d-old hyperbilirubinemic (jj) Gunn rat pups before and after administration of sulphadimethoxine to acutely displace bilirubin from plasma albumin." | 1.38 | Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups. ( Berengeno, AL; Gazzin, S; Giraudi, PJ; Konickova, R; Raseni, A; Robert, MC; Tiribelli, C; Vitek, L; Zabetta, CC; Zdrahalova, L; Zelenka, J, 2012) |
| "Bilirubin toxicity causes encephalopathy associated with lesions of the central auditory nervous system." | 1.28 | Binaural effects in brainstem auditory evoked potentials of jaundiced Gunn rats. ( Shapiro, SM, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaniary, KD | 1 |
| Baron, MS | 1 |
| Rice, AC | 3 |
| Wetzel, PA | 1 |
| Ramakrishnan, V | 1 |
| Shapiro, SM | 8 |
| Gazzin, S | 1 |
| Zelenka, J | 1 |
| Zdrahalova, L | 1 |
| Konickova, R | 1 |
| Zabetta, CC | 1 |
| Giraudi, PJ | 1 |
| Berengeno, AL | 1 |
| Raseni, A | 1 |
| Robert, MC | 1 |
| Vitek, L | 1 |
| Tiribelli, C | 1 |
| Shaia, WT | 1 |
| Spencer, RF | 1 |
| Daood, MJ | 1 |
| Watchko, JF | 1 |
| Geiger, AS | 1 |
| Sombati, S | 1 |
| Geiger, A | 1 |
| Conlee, JW | 1 |
| Yeary, RA | 1 |
| Wise, KJ | 1 |
| Davis, DR | 1 |
| Ballowitz, L | 1 |
| Hanefeld, F | 1 |
| Jerofke, R | 1 |
| Keller, P | 1 |
| Korn, J | 1 |
| Schweitzer, U | 1 |
| Smirnov, AN | 1 |
13 other studies available for sulfadimethoxine and Jaundice
| Article | Year |
|---|---|
Quantification of gait in dystonic Gunn rats.
Topics: Animals; Anti-Infective Agents; Biomechanical Phenomena; Disability Evaluation; Disease Models, Anim | 2009 |
Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups.
Topics: Albumins; Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter | 2012 |
The jaundiced gunn rat model of auditory neuropathy/dyssynchrony.
Topics: Animals; Animals, Newborn; Auditory Cortex; Axons; Brain Stem; Cochlear Nerve; Disease Models, Anima | 2005 |
Calculated in vivo free bilirubin levels in the central nervous system of Gunn rat pups.
Topics: Albumins; Animals; Animals, Newborn; Bilirubin; Central Nervous System; Cerebellum; Female; Heterozy | 2006 |
Minocycline blocks acute bilirubin-induced neurological dysfunction in jaundiced Gunn rats.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Anti-Infective Agents; Bilirubin; Disease Models, | 2007 |
NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity.
Topics: Animals; Animals, Newborn; Anti-Infective Agents; Bilirubin; Cell Survival; Disease Models, Animal; | 2007 |
Reversible brainstem auditory evoked potential abnormalities in jaundiced Gunn rats given sulfonamide.
Topics: Animals; Bilirubin; Brain; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Humans; | 1993 |
Development of cerebellar hypoplasia in jaundiced Gunn rats: a quantitative light microscopic analysis.
Topics: Aging; Animals; Bilirubin; Cerebellar Diseases; Cerebellum; Female; Heterozygote; Homozygote; Jaundi | 1997 |
Effects of bilirubin on glucuronidation of p-nitrophenol and morphine.
Topics: Animals; Bile Ducts; Bilirubin; Glucuronates; Glucuronosyltransferase; In Vitro Techniques; Jaundice | 1977 |
Sephadex-gel filtration (SGF) in infant and adult Gunn rats.
Topics: Age Factors; Animals; Bilirubin; Chromatography, Gel; Jaundice; Nutrition Disorders; Rats; Serum Alb | 1978 |
Binaural effects in brainstem auditory evoked potentials of jaundiced Gunn rats.
Topics: Animals; Bilirubin; Brain Diseases; Ear; Evoked Potentials, Auditory, Brain Stem; Jaundice; Rats; Ra | 1991 |
[Acute drug-induced hemolytic anemia].
Topics: Acute Disease; Adult; Anemia, Hemolytic; Aspirin; Diagnosis, Differential; Female; Glucosephosphate | 1989 |
Acute brainstem auditory evoked potential abnormalities in jaundiced Gunn rats given sulfonamide.
Topics: Animals; Evoked Potentials, Auditory; Humans; Jaundice; Rats; Rats, Gunn; Reaction Time; Serum Album | 1988 |