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sulfadimethoxine and Bilirubinemia

sulfadimethoxine has been researched along with Bilirubinemia in 9 studies

Sulfadimethoxine: A sulfanilamide that is used as an anti-infective agent.
sulfadimethoxine : A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position.

Research Excerpts

ExcerptRelevanceReference
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)
"To determine the effects of albumin on BAEPs and brain bilirubin content in two Gunn rat pup models of acute hyperbilirubinemia."3.79Albumin administration protects against bilirubin-induced auditory brainstem dysfunction in Gunn rat pups. ( Rice, AC; Schreuder, AB; Shapiro, SM; Vanikova, J; Verkade, HJ; Vitek, L, 2013)
"Excessive hyperbilirubinemia in human neonates can cause permanent dysfunction of the auditory system, as assessed with brainstem auditory evoked potentials (BAEPs)."3.77Profile of minocycline neuroprotection in bilirubin-induced auditory system dysfunction. ( Chiou, VL; Rice, AC; Shapiro, SM; Zuckoff, SB, 2011)
"Bilirubin encephalopathy or kernicterus is a potentially serious complication of neonatal hyperbilirubinemia."3.74NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity. ( Geiger, A; Rice, AC; Shapiro, SM; Sombati, S, 2007)
" We calculated in vivo CNS B(F) levels in Gunn rat pups (15-19 d old; heterozygous nonjaundiced Gunn rats (J/j) and homozygous jaundiced Gunn rats (j/j); saline or sulfadimethoxine treated) based on 1) total brain bilirubin (TBB) content, 2) brain albumin level, 3) CNS bilirubin binding capacity attributable to brain albumin determined using an ultrafiltration technique, and 4) published Gunn rat albumin-bilirubin binding constants (k)."3.73Calculated in vivo free bilirubin levels in the central nervous system of Gunn rat pups. ( Daood, MJ; Watchko, JF, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tukey, RH1
Strassburg, CP1
Schreuder, AB1
Rice, AC3
Vanikova, J1
Vitek, L1
Shapiro, SM3
Verkade, HJ1
Haustein, MD1
Read, DJ1
Steinert, JR1
Pilati, N1
Dinsdale, D1
Forsythe, ID1
Chiou, VL1
Zuckoff, SB1
Daood, MJ1
Watchko, JF1
Sombati, S1
Geiger, A1
Johnson, JA1
Hayward, JJ1
Kornguth, SE1
Siegel, FL1
Davis, DR2
Yeary, RA2

Reviews

1 review available for sulfadimethoxine and Bilirubinemia

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000

Other Studies

8 other studies available for sulfadimethoxine and Bilirubinemia

ArticleYear
Albumin administration protects against bilirubin-induced auditory brainstem dysfunction in Gunn rat pups.
    Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:10

    Topics: Analysis of Variance; Animals; Bilirubin; Evoked Potentials, Auditory, Brain Stem; Hyperbilirubinemi

2013
Acute hyperbilirubinaemia induces presynaptic neurodegeneration at a central glutamatergic synapse.
    The Journal of physiology, 2010, Dec-01, Volume: 588, Issue:Pt 23

    Topics: Acute Disease; Animals; Female; Hearing Loss; Hyperbilirubinemia; Male; Neurons; Patch-Clamp Techniq

2010
Profile of minocycline neuroprotection in bilirubin-induced auditory system dysfunction.
    Brain research, 2011, Jan-12, Volume: 1368

    Topics: Animals; Animals, Newborn; Bilirubin; Brain; Disease Models, Animal; Evoked Potentials, Auditory, Br

2011
Calculated in vivo free bilirubin levels in the central nervous system of Gunn rat pups.
    Pediatric research, 2006, Volume: 60, Issue:1

    Topics: Albumins; Animals; Animals, Newborn; Bilirubin; Central Nervous System; Cerebellum; Female; Heterozy

2006
NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity.
    Neonatology, 2007, Volume: 92, Issue:4

    Topics: Animals; Animals, Newborn; Anti-Infective Agents; Bilirubin; Cell Survival; Disease Models, Animal;

2007
Effects of hyperbilirubinaemia on glutathione S-transferase isoenzymes in cerebellar cortex of the Gunn rat.
    The Biochemical journal, 1993, Apr-15, Volume: 291 ( Pt 2)

    Topics: Aging; Animals; Brain; Cerebellar Cortex; Chromatography, High Pressure Liquid; Cytosol; Glutathione

1993
Effects of sulfadimethoxine on tissue distribution of (14C)bilirubin in the newborn and adult hyperbilirubinemic Gunn rate.
    Pediatric research, 1975, Volume: 9, Issue:11

    Topics: Animals; Animals, Newborn; Bilirubin; Brain; Digestive System; Female; Humans; Hyperbilirubinemia; L

1975
Protein binding of bilirubin: comparison of in vitro and in vivo measurements of bilirubin displacement by drugs.
    Toxicology and applied pharmacology, 1974, Volume: 28, Issue:2

    Topics: Animals; Azo Compounds; Benzoates; Bilirubin; Binding, Competitive; Blood Proteins; Chromatography,

1974