sulfadiazine has been researched along with Uremia in 4 studies
Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
sulfadiazine : A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.
diazine : The parent structure of the diazines.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Scatchard plots for sulfadiazine binding in plasma from patients with uremia and in normal plasma carbamylated in vitro with potassium cyanate showed changes in the 2 groups when compared with those in normal individuals." | 3.66 | Plasma protein carbamylation and decreased acidic drug protein binding in uremia. ( Calvo, R; Carlos, R; Erill, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erill, S | 1 |
| Calvo, R | 1 |
| Carlos, R | 1 |
| Seppänen, J | 1 |
| Viranta, M | 1 |
| Julkunen, R | 1 |
| Wilén, G | 1 |
| Boobis, SW | 1 |
| Ollstein, RN | 1 |
| Symonds, FC | 1 |
| Crikelair, GF | 1 |
| Pelle, L | 1 |
4 other studies available for sulfadiazine and Uremia
| Article | Year |
|---|---|
Plasma protein carbamylation and decreased acidic drug protein binding in uremia.
Topics: Adult; Binding Sites; Binding, Competitive; Blood Proteins; Carbamates; Charcoal; Cyanates; Female; | 1980 |
Pharmacokinetics of low dose sulfadiazine in patients with renal failure.
Topics: Acetylation; Adult; Aged; Blood Proteins; Female; Humans; Kinetics; Male; Middle Aged; Protein Bindi | 1980 |
Alteration of plasma albumin in relation to decreased drug binding in uremia.
Topics: Adult; Aged; Amino Acids; Female; Humans; Immunodiffusion; Isoelectric Focusing; Kidney Failure, Chr | 1977 |
Alternate case study of topical sulfamylon and silver sulfadiazine in burns.
Topics: Acidosis; Adolescent; Adult; Anemia; Burns; Child; Child, Preschool; Female; Humans; Male; Pseudomon | 1971 |