Page last updated: 2024-11-04

sulfadiazine and Hypertrophy

sulfadiazine has been researched along with Hypertrophy in 3 studies

Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
sulfadiazine : A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.
diazine : The parent structure of the diazines.

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
"Compared to nonoperative treatment with silver sulfadiazine cream, early excision and grafting of 22 patients with indeterminant burns of less than 20% TBSA resulted in an average shorter hospitalization, lower cost, and less time away from work than 25 patients treated nonoperatively."5.05Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study. ( Engrav, LH; Harnar, TJ; Heimbach, DM; Marvin, JA; Reus, JL, 1983)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SCHMELZ, W1
Engrav, LH1
Heimbach, DM1
Reus, JL1
Harnar, TJ1
Marvin, JA1
Hsueh, W1
Rostorfer, HH1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Tranexamic Acid (TXA) on Blood Loss and Transfusion Rates in Burn Wound Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT02753816]25 participants (Actual)Interventional2016-04-30Terminated (stopped due to Study enrollment and goals unable to be reached.)
Cost-effectiveness of Laser Doppler Imaging in Burn Care in the Netherlands[NCT01489540]200 participants (Anticipated)Interventional2011-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Blood Transfusion Rates, Defined Nominally (Binary) as Having at Least One Transfusion

To determine the impact of perioperative administration of Tranexamic Acid on transfusion rates in major burn surgeries. (NCT02753816)
Timeframe: First burn surgery to hospital discharge

InterventionPatients with 1 or more transfusions (Number)
Tranexamic Acid2
Placebo3

Effect of Tranexamic Acid on the Total Length of Hospital Admission for a Large (350 cm2) Burn Injury

To determine the impact of Tranexamic Acid on total hospital length of stay by comparing the hospital admission date and the hospital discharge date. This determination will take into account current burn size and location, procedures performed and their effect on wound healing and skin graft survival. (NCT02753816)
Timeframe: Hospital admission to hospital discharge

InterventionDays (Median)
Tranexamic Acid23
Placebo9

Intraoperative Blood Loss in mL

To determine the impact of perioperative administration of Tranexamic Acid on blood loss in major burn surgeries. (NCT02753816)
Timeframe: Intraoperative, average 122 minutes

InterventionmL (Median)
Tranexamic Acid100
Placebo325

Trials

1 trial available for sulfadiazine and Hypertrophy

ArticleYear
Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study.
    The Journal of trauma, 1983, Volume: 23, Issue:11

    Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix; Clinical Trials as Topic; Female;

1983
Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study.
    The Journal of trauma, 1983, Volume: 23, Issue:11

    Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix; Clinical Trials as Topic; Female;

1983
Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study.
    The Journal of trauma, 1983, Volume: 23, Issue:11

    Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix; Clinical Trials as Topic; Female;

1983
Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study.
    The Journal of trauma, 1983, Volume: 23, Issue:11

    Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix; Clinical Trials as Topic; Female;

1983

Other Studies

2 other studies available for sulfadiazine and Hypertrophy

ArticleYear
[Clinical experiences with solu-supronal with special reference to coli infections in cystitis and prostate hypertrophy].
    Zeitschrift fur Urologie, 1953, Volume: 46, Issue:8

    Topics: Cystitis; Drug Combinations; Escherichia coli; Escherichia coli Infections; Humans; Hypertrophy; Mal

1953
Chemically induced renal hypertrophy in the rat.
    Laboratory investigation; a journal of technical methods and pathology, 1973, Volume: 29, Issue:5

    Topics: Adrenalectomy; Alanine Transaminase; Alkaline Phosphatase; Animals; Autoradiography; Blood Urea Nitr

1973