sulfadiazine has been researched along with Cicatrix in 3 studies
Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
sulfadiazine : A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.
diazine : The parent structure of the diazines.
Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Compared to nonoperative treatment with silver sulfadiazine cream, early excision and grafting of 22 patients with indeterminant burns of less than 20% TBSA resulted in an average shorter hospitalization, lower cost, and less time away from work than 25 patients treated nonoperatively." | 5.05 | Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study. ( Engrav, LH; Harnar, TJ; Heimbach, DM; Marvin, JA; Reus, JL, 1983) |
| "Many children with congenital toxoplasmosis have substantial retinal damage at birth and consequent loss of vision." | 1.30 | Eye manifestations of congenital toxoplasmosis. ( Boyer, KM; Holfels, E; Hopkins, J; Luciano, R; Mack, D; McLeod, R; Meier, P; Mets, MB; Patel, D; Remington, JS; Roizen, N; Stein, L; Stein, M; Swisher, CN; Withers, S, 1997) |
| "A rabbit serosal scarification model was utilized to compare the ability of four drugs, previously administered peri-operatively to horses undergoing exploratory celiotomy, to prevent the development of postoperative intestinal adhesions." | 1.29 | Utilization of the serosal scarification model of postoperative intestinal adhesion formation to investigate potential adhesion-preventing substances in the rabbit. ( Barker, IK; Conlon, PD; Hurtig, MB; Livesey, MA; Singer, ER, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Engrav, LH | 1 |
| Heimbach, DM | 1 |
| Reus, JL | 1 |
| Harnar, TJ | 1 |
| Marvin, JA | 1 |
| Singer, ER | 1 |
| Livesey, MA | 1 |
| Barker, IK | 1 |
| Hurtig, MB | 1 |
| Conlon, PD | 1 |
| Mets, MB | 1 |
| Holfels, E | 1 |
| Boyer, KM | 1 |
| Swisher, CN | 1 |
| Roizen, N | 1 |
| Stein, L | 1 |
| Stein, M | 1 |
| Hopkins, J | 1 |
| Withers, S | 1 |
| Mack, D | 1 |
| Luciano, R | 1 |
| Patel, D | 1 |
| Remington, JS | 1 |
| Meier, P | 1 |
| McLeod, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Tranexamic Acid (TXA) on Blood Loss and Transfusion Rates in Burn Wound Surgery - A Randomized, Double-Blinded Placebo-Controlled Trial[NCT02753816] | 25 participants (Actual) | Interventional | 2016-04-30 | Terminated (stopped due to Study enrollment and goals unable to be reached.) | |||
| Cost-effectiveness of Laser Doppler Imaging in Burn Care in the Netherlands[NCT01489540] | 200 participants (Anticipated) | Interventional | 2011-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
To determine the impact of perioperative administration of Tranexamic Acid on transfusion rates in major burn surgeries. (NCT02753816)
Timeframe: First burn surgery to hospital discharge
| Intervention | Patients with 1 or more transfusions (Number) |
|---|---|
| Tranexamic Acid | 2 |
| Placebo | 3 |
To determine the impact of Tranexamic Acid on total hospital length of stay by comparing the hospital admission date and the hospital discharge date. This determination will take into account current burn size and location, procedures performed and their effect on wound healing and skin graft survival. (NCT02753816)
Timeframe: Hospital admission to hospital discharge
| Intervention | Days (Median) |
|---|---|
| Tranexamic Acid | 23 |
| Placebo | 9 |
To determine the impact of perioperative administration of Tranexamic Acid on blood loss in major burn surgeries. (NCT02753816)
Timeframe: Intraoperative, average 122 minutes
| Intervention | mL (Median) |
|---|---|
| Tranexamic Acid | 100 |
| Placebo | 325 |
1 trial available for sulfadiazine and Cicatrix
| Article | Year |
|---|---|
Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study.
Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix; Clinical Trials as Topic; Female; | 1983 |
Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study.
Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix; Clinical Trials as Topic; Female; | 1983 |
Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study.
Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix; Clinical Trials as Topic; Female; | 1983 |
Early excision and grafting vs. nonoperative treatment of burns of indeterminant depth: a randomized prospective study.
Topics: Adolescent; Adult; Aged; Burns; Child; Child, Preschool; Cicatrix; Clinical Trials as Topic; Female; | 1983 |
2 other studies available for sulfadiazine and Cicatrix
| Article | Year |
|---|---|
Utilization of the serosal scarification model of postoperative intestinal adhesion formation to investigate potential adhesion-preventing substances in the rabbit.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Carboxymeth | 1996 |
Eye manifestations of congenital toxoplasmosis.
Topics: Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Choroid Diseases; Cicatrix; Femal | 1997 |