Page last updated: 2024-11-04

sulfadiazine and Central Nervous System Toxoplasmosis

sulfadiazine has been researched along with Central Nervous System Toxoplasmosis in 97 studies

Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
sulfadiazine : A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.
diazine : The parent structure of the diazines.

Research Excerpts

ExcerptRelevanceReference
"The preferred therapeutic regimen for Toxoplasma encephalitis (TE) is a combination of pyrimethamine and sulfadiazine, and trimethoprim-sulfamethoxazole (TMP-SMX) plus azithromycin is the widespread alternative therapeutic regimen."9.51Synergistic sulfonamides plus clindamycin as an alternative therapeutic regimen for HIV-associated Toxoplasma encephalitis: a randomized controlled trial. ( Chen, H; Chen, Y; He, X; Huang, Y; Li, Y; Lu, Y; Wu, Y; Zeng, Y; Zhang, W, 2022)
"An open, randomised, multicentre trial was conducted to evaluate the efficacy of thrice-weekly versus daily therapy with sulfadiazine-pyrimethamine in the prevention of relapses of toxoplasmic encephalitis in HIV-infected patients."9.09Thrice-weekly sulfadiazine-pyrimethamine for maintenance therapy of toxoplasmic encephalitis in HIV-infected patients. Spanish Toxoplasmosis Study Group. ( Arrizabalaga, J; Cosin, J; Cruceta, A; Domingo, P; Fariñas, MC; Ferrer, E; Gatell, JM; Gudiol, F; Knobel, H; Leyes, M; Martínez-Lacasa, J; Miró, JM; Podzamczer, D; Polo, R; Ramón, JM; Ribera, E; Sirera, G, 2000)
"To evaluate the efficacy and tolerance of atovaquone used as long-term maintenance therapy in patients with toxoplasmic encephalitis and intolerant of conventional anti-Toxoplasma therapies."9.08Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group. ( Gourdon, D; Katlama, C; Lapierre, D; Mouthon, B; Rousseau, F, 1996)
"Between February 1990 and June 1993, 105 patients with HIV infection were enrolled after each had had resolution of an acute episode of toxoplasmic encephalitis treated with sulfadiazine (1 g four times per day) plus pyrimethamine (50 mg/d) plus folinic acid (15 mg/d) for 4 to 8 weeks."9.08Twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent recurrent toxoplasmic encephalitis in patients with AIDS. Spanish Toxoplasmosis Study Group. ( Bolao, F; Cosín, J; Domingo, P; Gatell, JM; Laguna, F; Miró, JM; Podzamczer, D; Santamaría, J; Sirera, G; Verdejo, J, 1995)
"This European multicenter study compares the efficacy and tolerance of the combination of pyrimethamine-clindamycin (Pyr-Cm) with the standard therapy pyrimethamine-sulfadiazine (Pyr-Sdz) for the treatment of toxoplasmic encephalitis (TE) in patients with AIDS."9.08Pyrimethamine-clindamycin vs. pyrimethamine-sulfadiazine as acute and long-term therapy for toxoplasmic encephalitis in patients with AIDS. ( Clumeck, N; De Wit, S; Katlama, C; O'Doherty, E; Van Glabeke, M, 1996)
"A prospective study was conducted to evaluate azithromycin in combination with pyrimethamine for treatment of acute Toxoplasma encephalitis in patients with AIDS."9.07Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. ( Hazebroucq, V; Joly, V; Leport, C; Morlat, P; Raffi, F; Saba, J; Vildé, JL, 1993)
"To compare pyrimethamine plus clindamycin (PC) to pyrimethamine plus sulfadiazine (PS) as a treatment for toxoplasmic encephalitis (TE) in patients with the acquired immunodeficiency syndrome (AIDS)."9.07Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group. ( Antoniskis, D; Chiu, J; Clumeck, N; Dannemann, B; Israelski, D; Leport, C; Luft, B; McCutchan, JA; Morlat, P; Nussbaum, J, 1992)
" The standard treatment for toxoplasmic encephalitis is pyrimethamine and sulfadiazine."7.71Treatment of Toxoplasma brain abscess with clindamycin and sulfadiazine in an AIDS patient with concurrent atypical Pneumocystis carinii pneumonia. ( Chen, ER; Chen, YS; Huang, CK; Lee, SS; Lin, HH; Lin, WR; Liu, YC; Tsai, HC, 2002)
"The effectiveness of combinations of rifabutin with atovaquone, clindamycin, pyrimethamine, or sulfadiazine in the treatment of toxoplasmic encephalitis in a murine model was investigated."7.69Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice. ( Araujo, FG; Remington, JS; Suzuki, Y, 1996)
"Patients with AIDS and Toxoplasma encephalitis may have several predisposing conditions that can lead to the development of sulfadiazine-induced crystalluria, including poor fluid intake, fever, diarrhea, and hypoalbuminemia, in addition to the high doses of the drug required and the prolonged period of treatment."7.69Sulfadiazine-induced multiple urolithiasis and acute renal failure in a patient with AIDS and Toxoplasma encephalitis. ( Collazos, J; Díaz, F; Martínez, E; Mayo, J, 1996)
"The preferred therapeutic regimen for Toxoplasma encephalitis (TE) is a combination of pyrimethamine and sulfadiazine, and trimethoprim-sulfamethoxazole (TMP-SMX) plus azithromycin is the widespread alternative therapeutic regimen."5.51Synergistic sulfonamides plus clindamycin as an alternative therapeutic regimen for HIV-associated Toxoplasma encephalitis: a randomized controlled trial. ( Chen, H; Chen, Y; He, X; Huang, Y; Li, Y; Lu, Y; Wu, Y; Zeng, Y; Zhang, W, 2022)
"An open, randomised, multicentre trial was conducted to evaluate the efficacy of thrice-weekly versus daily therapy with sulfadiazine-pyrimethamine in the prevention of relapses of toxoplasmic encephalitis in HIV-infected patients."5.09Thrice-weekly sulfadiazine-pyrimethamine for maintenance therapy of toxoplasmic encephalitis in HIV-infected patients. Spanish Toxoplasmosis Study Group. ( Arrizabalaga, J; Cosin, J; Cruceta, A; Domingo, P; Fariñas, MC; Ferrer, E; Gatell, JM; Gudiol, F; Knobel, H; Leyes, M; Martínez-Lacasa, J; Miró, JM; Podzamczer, D; Polo, R; Ramón, JM; Ribera, E; Sirera, G, 2000)
"To evaluate the efficacy and tolerance of atovaquone used as long-term maintenance therapy in patients with toxoplasmic encephalitis and intolerant of conventional anti-Toxoplasma therapies."5.08Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group. ( Gourdon, D; Katlama, C; Lapierre, D; Mouthon, B; Rousseau, F, 1996)
"Between February 1990 and June 1993, 105 patients with HIV infection were enrolled after each had had resolution of an acute episode of toxoplasmic encephalitis treated with sulfadiazine (1 g four times per day) plus pyrimethamine (50 mg/d) plus folinic acid (15 mg/d) for 4 to 8 weeks."5.08Twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent recurrent toxoplasmic encephalitis in patients with AIDS. Spanish Toxoplasmosis Study Group. ( Bolao, F; Cosín, J; Domingo, P; Gatell, JM; Laguna, F; Miró, JM; Podzamczer, D; Santamaría, J; Sirera, G; Verdejo, J, 1995)
"This European multicenter study compares the efficacy and tolerance of the combination of pyrimethamine-clindamycin (Pyr-Cm) with the standard therapy pyrimethamine-sulfadiazine (Pyr-Sdz) for the treatment of toxoplasmic encephalitis (TE) in patients with AIDS."5.08Pyrimethamine-clindamycin vs. pyrimethamine-sulfadiazine as acute and long-term therapy for toxoplasmic encephalitis in patients with AIDS. ( Clumeck, N; De Wit, S; Katlama, C; O'Doherty, E; Van Glabeke, M, 1996)
"To compare pyrimethamine plus clindamycin (PC) to pyrimethamine plus sulfadiazine (PS) as a treatment for toxoplasmic encephalitis (TE) in patients with the acquired immunodeficiency syndrome (AIDS)."5.07Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group. ( Antoniskis, D; Chiu, J; Clumeck, N; Dannemann, B; Israelski, D; Leport, C; Luft, B; McCutchan, JA; Morlat, P; Nussbaum, J, 1992)
"A prospective study was conducted to evaluate azithromycin in combination with pyrimethamine for treatment of acute Toxoplasma encephalitis in patients with AIDS."5.07Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. ( Hazebroucq, V; Joly, V; Leport, C; Morlat, P; Raffi, F; Saba, J; Vildé, JL, 1993)
" The standard treatment for toxoplasmic encephalitis is pyrimethamine and sulfadiazine."3.71Treatment of Toxoplasma brain abscess with clindamycin and sulfadiazine in an AIDS patient with concurrent atypical Pneumocystis carinii pneumonia. ( Chen, ER; Chen, YS; Huang, CK; Lee, SS; Lin, HH; Lin, WR; Liu, YC; Tsai, HC, 2002)
"In 26 AIDS patients treated for toxoplasmic encephalitis, the inhibitory effect on Toxoxplasma growth of sequential sera taken before and after initiation of therapy was determined using a culture-based immunoassay and compared with pyrimethamine blood levels."3.70Determination of the inhibitory effect on Toxoplasma growth in the serum of AIDS patients during acute therapy for toxoplasmic encephalitis. ( Derouin, F; Farinotti, R; Gérard, L; Leport, C; Maslo, C, 1998)
"The effectiveness of combinations of rifabutin with atovaquone, clindamycin, pyrimethamine, or sulfadiazine in the treatment of toxoplasmic encephalitis in a murine model was investigated."3.69Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice. ( Araujo, FG; Remington, JS; Suzuki, Y, 1996)
"Patients with AIDS and Toxoplasma encephalitis may have several predisposing conditions that can lead to the development of sulfadiazine-induced crystalluria, including poor fluid intake, fever, diarrhea, and hypoalbuminemia, in addition to the high doses of the drug required and the prolonged period of treatment."3.69Sulfadiazine-induced multiple urolithiasis and acute renal failure in a patient with AIDS and Toxoplasma encephalitis. ( Collazos, J; Díaz, F; Martínez, E; Mayo, J, 1996)
"11), and drug discontinuation because of adverse events (P-C: RR 0."2.55A systematic review and meta-analysis of the relative efficacy and safety of treatment regimens for HIV-associated cerebral toxoplasmosis: is trimethoprim-sulfamethoxazole a real option? ( Benites-Zapata, VA; Deshpande, A; Hernandez, AV; Pasupuleti, V; Pellegrino, D; Penalva de Oliveira, AC; Thota, P; Vidal, JE, 2017)
" Dosage must be adjusted to the results of blood counts."2.38[Usefulness of folinic acid in cytopenia induced by antiparasitic drugs in AIDS patients]. ( Leport, C; Niyongabo, T; Vildé, JL, 1991)
"The simultaneous occurrence of cerebral toxoplasmosis and cryptococcosis is rare."1.91A Case of Cerebral Toxoplasmosis and Cryptococcosis Preferred Therapy Associated Adverse Drug Reactions in a Patient Newly Co-diagnosed with Acquired Immune Deficiency Syndrome. ( Panda, BK; Purandare, B; Rege, S; Suryawanshi, VR, 2023)
"This study showed that a 10-day treatment with 20 mg/kg of fluconazole combined with sulfadiazine and pyrimethamine 1."1.62Determination of parasitic burden in the brain tissue of infected mice in acute toxoplasmosis after treatment by fluconazole combined with sulfadiazine and pyrimethamine. ( Anita, M; Hadi, M; Mohammad, JM; Reza, S; Sina, S; Soudabeh, E, 2021)
"The current standard treatment for cerebral toxoplasmosis (pyrimethamine/sulfadiazine) often encounters problems of poor tolerability, adverse effects, frequent dropouts and non-availability of pyrimethamine/sulfadiazine in some parts of India."1.42Alternative treatment approach to cerebral toxoplasmosis in HIV/AIDS: experience from a resource-poor setting. ( Goswami, RP; Rahman, M; Ray, Y; Tripathi, SK, 2015)
"Severe forms of cerebral toxoplasmosis in patients with HIV infection are characterized by a good prognosis in approximately 50% of cases."1.38Neurologic outcomes and adjunctive steroids in HIV patients with severe cerebral toxoplasmosis. ( Ait Hssain, A; Bouadma, L; da Silva, D; Klein, IF; Messika, J; Mourvillier, B; Schmidt, M; Sonneville, R; Wolff, M, 2012)
"The retrieved renal calculi were negative for the common stones that are routinely tested for in our laboratory and had the macroscopic characteristics of a sulphadiazine stone."1.38Sulphadiazine-induced renal stones in a 63-year-old HIV-infected man treated for toxoplasmosis. ( Hew, M; McGettigan, BD; McLean-Tooke, A; Phillips, E, 2012)
"Sulfadiazine was withdrawn after 14-21 days to allow reactivation."1.34The timing of sulfadiazine therapy impacts the reactivation of latent Toxoplasma infection in IRF-8-/- mice. ( Jost, C; Liesenfeld, O; Reiter-Owona, I, 2007)
"Atovaquone was detectable in sera, brains, livers, and lungs of infected mice by high-performance liquid chromatography and/or mass spectrometry."1.32Atovaquone maintenance therapy prevents reactivation of toxoplasmic encephalitis in a murine model of reactivated toxoplasmosis. ( Arasteh, K; Borner, K; Bushrab, FN; Dunay, IR; Fitzner, R; Heimesaat, MM; Kurowski, M; Liesenfeld, O; Müller, RH; Stocker, H, 2004)
"Six patients had cerebral toxoplasmosis diagnosed on the basis of neurological signs and observation of the patients' mental confusion, seizures, and typical lesions (which were assessed by computed tomography, magnetic resonance imaging, or both)."1.31Toxoplasmosis, a severe complication in allogeneic hematopoietic stem cell transplantation: successful treatment strategies during a 5-year single-center experience. ( Basara, N; Bischoff, M; Blau, IW; Fauser, AA; Günzelmann, S; Kiehl, MG; Kirsten, D; Roemer, E; Sanchez, H; Wocker, EL, 2001)
"Neurotoxoplasmosis was the most frequent presenting symptom of AIDS (53."1.30[Cerebral toxoplasmosis and AIDS in Martinique]. ( Bourée, P; Dumazedier, D; Magdeleine, C; Sobesky, G, 1997)
"Cerebral toxoplasmosis is a rare late complication in allogeneic bone marrow transplanted patients."1.30Post-transplant cerebral toxoplasmosis diagnosed by magnetic resonance imaging. ( De Rosa, G; Di Salle, F; Pezzullo, L; Picardi, M; Raiola, A; Rotoli, B, 1998)
"In particular, in patients with AIDS who are more susceptible for adverse drug reactions and who are simultaneously receiving a variety of drugs with a considerable potential of cutaneous side effects, therapy cannot be withhold for lack of therapeutic alternatives."1.29[Drug-induced Stevens-Johnson syndrome in a patient with AIDS]. ( Bircher, A; Haefeli, WE; Leib, SL; Lüscher, TF; Schlienger, RG, 1993)
"A pregnant woman was diagnosed with central nervous system toxoplasmosis and human immunodeficiency virus infection."1.29Normal fetal outcome in a pregnancy with central nervous system toxoplasmosis and human immunodeficiency virus infection. A case report. ( Brown, GM; Hedriana, HL; Mitchell, JL; Williams, SB, 1993)
"Cerebral toxoplasmosis is the most common opportunistic infection of the central nervous system in AIDS patients."1.29[Therapeutic alternatives for cases of cerebral toxoplasmosis in patients with AIDS: clarithromycin and atovaquone]. ( Cardenal, C; Gatell, JM; Guelar, A; Mallolas, J; Miró, JM; Soriano, E; Zamora, L, 1994)
"Three of 50 (6%) had hemichoreoathetosis."1.29Choreoathetosis in acquired immune deficiency syndrome patients with cerebral toxoplasmosis. ( Andreula, C; Angarano, G; Armenise, S; De Blasi, R; de Mari, M; Maggi, P; Romanelli, C; Zimatore, G, 1996)
"Sulfadiazine-nephropathy and -nephrolithiasis were well known complications of high dose sulfadiazine therapy 50 years ago."1.29[Sulfadiazine nephrolithiasis and nephropathy]. ( Furrer, H; Hess, B; Jaeger, P; von Overbeck, J, 1994)
"Ten (91%) of these 11 patients with recurrence showed focal persistent enhancement after the initial treatment of toxoplasmosis abscess."1.29Persistent enhancement after treatment for cerebral toxoplasmosis in patients with AIDS: predictive value for subsequent recurrence. ( Benmelha, Z; Bouvet, E; Casalino, E; Laissy, JP; Lariven, S; Parlier, C; Servois, V; Sibert, A; Soyer, P; Vachon, F, 1994)
"The survival from AIDS or CD4 count = 50 cells/mm3 did not differ significantly between those with treated CTOX and a control group who had no toxoplasma infection, suggesting that treatment is reasonably effective."1.29Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients. ( Brettle, RP; Burns, SM; Flegg, PJ; Laing, RB; Leen, CL, 1996)
"Sulphadiazine-induced crystalluria and acute renal failure is increasingly frequent."1.29Acute renal failure due to sulphadiazine crystalluria in AIDS patients. ( Abad, J; Albalate, M; Caramelo, C; Casado, S; de Sequera, P; Fernández Guerrero, M; Hernandez, J; Ortiz, A; Ramiro, E; Vazquez, A, 1996)
"Treatment with pyrimethamine plus sulfadiazine produced clinical cures in 100% of the infected mice 1 month after infection."1.29A clinical-parasitological monotherapy cure in the treatment of experimental infection by a highly virulent strain of Toxoplasma gondii. ( Arribas, JR; de Diego, JA; Penin, P; Vázquez, E; Vázquez, JJ, 1996)
"ET was the AIDS-defining condition in 44% of the patients."1.29[Cerebral toxoplasmosis in patients with human immunodeficiency virus (HIV) infection. Clinico-radiological and therapeutic aspects in 63 patients]. ( Barrio, JL; Cadafalch, J; Domingo, P; Ferrer, S; Fuentes, I; Fuster, M; Iranzo, A; Muñoz, C; Nolla, J; Ris, J; Sambeat, MA, 1996)
"Cerebral toxoplasmosis is optimally treated with the combination of high doses of sulphadiazine and pyrimethamine."1.29Renal failure due to sulphadiazine in AIDS patients with cerebral toxoplasmosis. ( Echevarría, S; Fariñas, MC; González, A; González-Macías, J; Pérez del Molino, A; Sampedro, I, 1993)
"One complication of this is acute renal failure secondary to sulphadiazine-induced crystalluria."1.29Renal ultrasonic findings in sulphadiazine-induced renal failure. ( Kane, D; Keating, S; Mulcahy, FM; Murphy, JM; Wilson, GF, 1996)

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's65 (67.01)18.2507
2000's14 (14.43)29.6817
2010's12 (12.37)24.3611
2020's6 (6.19)2.80

Authors

AuthorsStudies
Patel, J1
Kuppachi, S1
Huffman, AM1
Ayariga, JA1
Napier, A1
Robertson, BK1
Abugri, DA1
Suryawanshi, VR1
Purandare, B1
Rege, S1
Panda, BK1
Li, Y2
Zeng, Y1
Lu, Y1
He, X1
Wu, Y1
Zhang, W1
Huang, Y1
Chen, H1
Chen, Y1
Zeng, YM1
Lu, YQ1
Qin, YY1
Chen, YK1
Sina, S1
Mohammad, JM1
Reza, S1
Anita, M1
Soudabeh, E1
Hadi, M1
Bejjanki, H1
Olaoye, OA1
Santos, AH1
Koratala, A1
Le Clech, L1
Hutin, P1
Le Gal, S1
Guillerm, G1
Olmos Soto, S1
Reus Bañuls, S1
Mora Castera, E1
Villarubia Lor, MB1
Goswami, RP2
Rahman, M1
Ray, Y1
Tripathi, SK1
Miyagi, T1
Itonaga, H1
Aosai, F1
Taguchi, J1
Norose, K1
Mochizuki, K1
Fujii, H1
Furumoto, A1
Ohama, M1
Karimata, K1
Yamanoha, A1
Taniguchi, H1
Sato, S1
Taira, N1
Moriuchi, Y1
Fukushima, T1
Masuzaki, H1
Miyazaki, Y1
Hernandez, AV1
Thota, P1
Pellegrino, D1
Pasupuleti, V1
Benites-Zapata, VA1
Deshpande, A1
Penalva de Oliveira, AC1
Vidal, JE1
Faucher, B1
Moreau, J1
Zaegel, O1
Franck, J1
Piarroux, R1
Diz, S1
Barbolla, I1
Egea, M1
de Luna, G1
Allinson, J1
Topping, W1
Edwards, SG1
Miller, RF1
Kanno, A1
Suzuki, Y2
Minami, M1
Ogawa, K1
Oishi, M1
Kamei, S1
McGettigan, BD1
Hew, M1
Phillips, E1
McLean-Tooke, A1
Sonneville, R1
Schmidt, M1
Messika, J1
Ait Hssain, A1
da Silva, D1
Klein, IF1
Bouadma, L1
Wolff, M1
Mourvillier, B1
Ball, SC1
Tsai, HC1
Lee, SS1
Lin, HH1
Lin, WR1
Chen, YS1
Huang, CK1
Liu, YC1
Chen, ER1
Lee, SA1
James, CW1
Szabo, S1
Dressler, RM1
Dunay, IR1
Heimesaat, MM1
Bushrab, FN1
Müller, RH1
Stocker, H1
Arasteh, K1
Kurowski, M1
Fitzner, R1
Borner, K1
Liesenfeld, O2
Holtkamp, M1
Okuducu, AF1
Klingebiel, R1
Ploner, CJ1
Di Carlo, P1
Mazzola, A1
Romano, A1
Schimmenti, MG1
Colicchia, P1
Bellipanni, P1
Titone, L1
Solano Remírez, M1
Oliván Ballabriga, AS1
da Costa Rodríguez, GM1
Alvarez Frías, MT1
González Arencibia, C1
Schuler, AK1
Talor, Z1
Jost, C1
Reiter-Owona, I1
de la Prada Alvarez, FJ1
Prados Gallardo, AM1
Tugores Vázquez, A1
Uriol Rivera, M1
Morey Molina, A1
Arens, J1
Barnes, K1
Crowley, N1
Maartens, G1
Winstanley, P1
Podzamczer, D2
Miró, JM3
Bolao, F1
Gatell, JM3
Cosín, J2
Sirera, G2
Domingo, P3
Laguna, F1
Santamaría, J1
Verdejo, J1
Kovacs, JA1
Langmann, P1
Klinker, H1
Richter, E1
Huber, W1
Bautz, W1
Classen, M1
Schepp, W1
Potter, JL1
Kofron, WG1
Laissy, JP1
Soyer, P1
Parlier, C1
Lariven, S1
Benmelha, Z1
Servois, V1
Casalino, E1
Bouvet, E1
Sibert, A1
Vachon, F1
Fernandez, JM1
Sadaba, F1
Villaverde, FJ1
Alvaro, LC1
Cortina, C1
Marques, LP1
Madeira, EP1
Santos, OR1
Furrer, H1
von Overbeck, J1
Jaeger, P1
Hess, B1
Oksenhendler, E1
Charreau, I1
Tournerie, C1
Azihary, M1
Carbon, C1
Aboulker, JP1
Guelar, A1
Mallolas, J1
Zamora, L1
Cardenal, C1
Soriano, E1
McAuley, J1
Boyer, KM2
Patel, D1
Mets, M1
Swisher, C1
Roizen, N1
Wolters, C1
Stein, L1
Stein, M1
Schey, W1
Walckenaer, G1
Leport, C5
Longuet, P1
Perronne, C1
Lacassin, F1
Vildé, JL3
Saba, J1
Morlat, P3
Raffi, F1
Hazebroucq, V1
Joly, V1
Araujo, FG3
Slifer, T2
Remington, JS3
Kronawitter, U1
Jakob, K1
Zoller, WG1
Rauh, G1
Goebel, FD1
McCabe, R1
Chirurgi, V1
Hedriana, HL1
Mitchell, JL1
Brown, GM1
Williams, SB1
Schlienger, RG1
Haefeli, WE1
Bircher, A1
Leib, SL1
Lüscher, TF1
Ragnaud, JM1
Dupon, M1
Lacoste, D1
Pellegrin, JL1
Chene, G1
Desguerre, I1
Pedespan, JM1
Buissonnière, R1
Couvreur, J1
Ponsot, G1
Nath, A1
Hobson, DE1
Russell, A1
Fariñas, MC3
Echevarría, S1
Sampedro, I1
González, A1
Pérez del Molino, A1
González-Macías, J2
Murray-Pulsifer, K1
Hein, R1
Brunkhorst, R1
Thon, WF1
Schedel, I1
Schmidt, RE1
Caumes, E1
Bocquet, H1
Guermonprez, G1
Rogeaux, O1
Bricaire, F1
Katlama, C3
Gentilini, M1
Van Delden, C1
Hirschel, B1
Patel, DV1
Holfels, EM1
Vogel, NP1
Mets, MB1
Swisher, CN1
Roizen, NJ1
Stein, LK1
Stein, MA1
Hopkins, J1
Withers, SE1
Mack, DG1
Luciano, RA1
Meier, P1
McLeod, RL1
Ferrer, S1
Fuentes, I1
Muñoz, C1
Iranzo, A1
Barrio, JL1
Fuster, M1
Ris, J1
Sambeat, MA1
Cadafalch, J1
Nolla, J1
Rodríguez-Carballeira, M1
Casagran, A1
Moré, J1
Argilaga, R1
García, M1
Wei, ME1
Campbell, SH1
Taylor, C1
Díaz, F1
Collazos, J1
Mayo, J1
Martínez, E1
Maggi, P1
de Mari, M1
De Blasi, R1
Armenise, S1
Romanelli, C1
Andreula, C1
Zimatore, G1
Angarano, G1
De Wit, S1
O'Doherty, E1
Van Glabeke, M1
Clumeck, N2
Mouthon, B1
Gourdon, D1
Lapierre, D1
Rousseau, F1
Laing, RB1
Flegg, PJ1
Brettle, RP1
Leen, CL1
Burns, SM1
de Sequera, P1
Albalate, M1
Hernandez, J1
Vazquez, A1
Abad, J1
Ramiro, E1
Fernández Guerrero, M1
Caramelo, C1
Casado, S1
Ortiz, A1
Kane, D1
Murphy, JM1
Keating, S1
Wilson, GF1
Mulcahy, FM1
de Diego, JA1
Penin, P1
Arribas, JR1
Vázquez, E1
Vázquez, JJ1
Hoetelmans, RM1
Kraaijeveld, CL1
Meenhorst, PL1
Mulder, JW1
Burger, DM1
Koks, CH1
Beijnen, JH1
de Luis, DA1
Fortun, J1
Pintado, V1
Aller de la Fuente, R1
Supiot, F1
Guillaume, MP1
Hermanus, N1
Telerman-Toppet, N1
Karmali, R1
Bourée, P1
Dumazedier, D1
Magdeleine, C1
Sobesky, G1
Sillevis Smitt, P1
Swaak, T1
Brinkman, K1
Debast, S1
Sauerwein, R1
Ooyman, F1
Hiel, J1
Raemaekers, J1
Campany, D1
Sales, P1
Grau, S1
Saballs, P1
Drobnic, L1
Gimeno, JL1
Arjol, AM1
Sánchez, C1
Dalmau, D1
Picardi, M1
De Rosa, G1
Di Salle, F1
Pezzullo, L1
Raiola, A1
Rotoli, B1
Derouin, F1
Gérard, L1
Farinotti, R1
Maslo, C2
Carrión-Carrión, C1
Morales-Suárez-Varela, MM1
Llopis-González, A1
Colebunders, R1
Depraetere, K1
De Droogh, E1
Kamper, A1
Corthout, B1
Bottiau, E1
Ferrer, E1
Ramón, JM1
Ribera, E1
Cruceta, A1
Knobel, H1
Polo, R1
Leyes, M1
Arrizabalaga, J2
Martínez-Lacasa, J1
Gudiol, F1
Roemer, E1
Blau, IW1
Basara, N1
Kiehl, MG1
Bischoff, M1
Günzelmann, S1
Kirsten, D1
Sanchez, H1
Wocker, EL1
Fauser, AA1
Fernández-Ayala, M1
Nan, D1
Kupila, L1
Sonninen, V1
Peltonen, R1
Uksila, J1
Hukkanen, V1
Kotilainen, P1
Iribarren, JA1
Garde, C1
Rodriguez-Arrondo, F1
Blanco, A1
Reboli, AC1
Mandler, HD1
De Jaureguiberry, JP1
Reboul, P1
Vey, N1
Jaubert, D1
Lüscher, C1
Horber, FF1
Iannucci, AA1
Hart, LL1
Corbella, X1
Mascaró, J1
Santín, M1
Carratalà, J1
Dannemann, B1
McCutchan, JA1
Israelski, D1
Antoniskis, D1
Luft, B1
Nussbaum, J1
Chiu, J1
de Gans, J1
Portegies, P1
Reiss, P1
Troost, D1
van Gool, T1
Lange, JM1
Fégueux, S1
De Truchis, P1
Balloul, H1
Matheron, S1
Coulaud, JP1
Niyongabo, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Dose-Escalation, Phase I/II Study of Oral Azithromycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS[NCT00000966]Phase 145 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for sulfadiazine and Central Nervous System Toxoplasmosis

ArticleYear
Successful treatment of toxoplasmic encephalitis diagnosed early by polymerase chain reaction after allogeneic hematopoietic stem cell transplantation: two case reports and review of the literature.
    Transplant infectious disease : an official journal of the Transplantation Society, 2015, Volume: 17, Issue:4

    Topics: Adult; Antiprotozoal Agents; Drug Therapy, Combination; Early Diagnosis; Hematopoietic Stem Cell Tra

2015
A systematic review and meta-analysis of the relative efficacy and safety of treatment regimens for HIV-associated cerebral toxoplasmosis: is trimethoprim-sulfamethoxazole a real option?
    HIV medicine, 2017, Volume: 18, Issue:2

    Topics: Adult; Antiprotozoal Agents; Clindamycin; Cohort Studies; Female; HIV Infections; Humans; Male; Midd

2017
[Acute kidney failure caused by sulfadiazine stones. A complication of the therapy of toxoplasmosis in AIDS].
    Deutsche medizinische Wochenschrift (1946), 1993, Nov-19, Volume: 118, Issue:46

    Topics: Acute Kidney Injury; AIDS-Related Opportunistic Infections; Clindamycin; Drug Therapy, Combination;

1993
Issues in toxoplasmosis.
    Infectious disease clinics of North America, 1993, Volume: 7, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Animals; Clindamycin; Drug Therapy, Combination; Encephalitis

1993
Movement disorders with cerebral toxoplasmosis and AIDS.
    Movement disorders : official journal of the Movement Disorder Society, 1993, Volume: 8, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Basal Ganglia Diseases; Cerebral Cortex; Chorea; Drug

1993
Clindamycin in the treatment of toxoplasmosis in AIDS.
    The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Humans; Pyrimethamine; Retrospective Studies; Sulfa

1992
[Usefulness of folinic acid in cytopenia induced by antiparasitic drugs in AIDS patients].
    Presse medicale (Paris, France : 1983), 1991, Oct-26, Volume: 20, Issue:34

    Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Folic Acid; Hematologic Diseases; Hum

1991

Trials

9 trials available for sulfadiazine and Central Nervous System Toxoplasmosis

ArticleYear
Synergistic sulfonamides plus clindamycin as an alternative therapeutic regimen for HIV-associated Toxoplasma encephalitis: a randomized controlled trial.
    Chinese medical journal, 2022, Nov-20, Volume: 135, Issue:22

    Topics: Acquired Immunodeficiency Syndrome; Azithromycin; Clindamycin; Encephalitis; Humans; Sulfadiazine; S

2022
A study for precision diagnosing and treatment strategies in difficult-to-treat AIDS cases and HIV-infected patients with highly fatal or highly disabling opportunistic infections.
    Medicine, 2020, Volume: 99, Issue:20

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-I

2020
Twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent recurrent toxoplasmic encephalitis in patients with AIDS. Spanish Toxoplasmosis Study Group.
    Annals of internal medicine, 1995, Aug-01, Volume: 123, Issue:3

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Drug Administration Schedule; Drug Therapy, Comb

1995
Early and longitudinal evaluations of treated infants and children and untreated historical patients with congenital toxoplasmosis: the Chicago Collaborative Treatment Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:1

    Topics: Animals; Calcinosis; Chemistry, Pharmaceutical; Child; Child, Preschool; Drug Administration Schedul

1994
Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:11

    Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Azithromycin; Drug Administration Sched

1993
Pyrimethamine-clindamycin vs. pyrimethamine-sulfadiazine as acute and long-term therapy for toxoplasmic encephalitis in patients with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 22, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Clindamycin; Drug Therapy, Comb

1996
Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group.
    AIDS (London, England), 1996, Volume: 10, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiprotozoal Agents; Atovaquone; Clindamycin; Encephalit

1996
Thrice-weekly sulfadiazine-pyrimethamine for maintenance therapy of toxoplasmic encephalitis in HIV-infected patients. Spanish Toxoplasmosis Study Group.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2000, Volume: 19, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Drug Therapy, Combination; Encep

2000
Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group.
    Annals of internal medicine, 1992, Jan-01, Volume: 116, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Clindamycin; Drug Evaluation; Drug Therapy, Combination;

1992

Other Studies

81 other studies available for sulfadiazine and Central Nervous System Toxoplasmosis

ArticleYear
AKI in a Patient with Cerebral Toxoplasmosis.
    Kidney360, 2020, Apr-30, Volume: 1, Issue:4

    Topics: Acute Kidney Injury; Humans; Sulfadiazine; Toxoplasmosis, Cerebral; Ureteral Calculi

2020
Inhibition of
    Frontiers in cellular and infection microbiology, 2022, Volume: 12

    Topics: Antiparasitic Agents; Humans; Quinidine; Sulfadiazine; Toxoplasma; Toxoplasmosis, Cerebral

2022
A Case of Cerebral Toxoplasmosis and Cryptococcosis Preferred Therapy Associated Adverse Drug Reactions in a Patient Newly Co-diagnosed with Acquired Immune Deficiency Syndrome.
    Current drug safety, 2023, Volume: 18, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Amphotericin B; Antifungal Agents; Coinfection; Cryptococ

2023
Determination of parasitic burden in the brain tissue of infected mice in acute toxoplasmosis after treatment by fluconazole combined with sulfadiazine and pyrimethamine.
    European journal of medical research, 2021, Jun-30, Volume: 26, Issue:1

    Topics: 14-alpha Demethylase Inhibitors; Acute Disease; Animals; Antiprotozoal Agents; Brain; Disease Models

2021
Liver transplant, toxoplasmosis and kidney stones: connecting the dots.
    BMJ case reports, 2019, Feb-15, Volume: 12, Issue:2

    Topics: Aftercare; Antimalarials; Antiprotozoal Agents; Atovaquone; Brain; Brain Edema; Female; Humans; Kidn

2019
Skin nodules in a patient with acute lymphoblastic leukaemia.
    BMJ case reports, 2014, Jan-09, Volume: 2014

    Topics: Adolescent; Amphotericin B; Cord Blood Stem Cell Transplantation; Dermatomycoses; Diagnosis, Differe

2014
[Cerebral toxoplasmosis in a patient with Waldenström's macroglobulinemia].
    Enfermedades infecciosas y microbiologia clinica, 2014, Volume: 32, Issue:8

    Topics: Aged; Antiprotozoal Agents; Biopsy; Cross Infection; Drug Therapy, Combination; Fatal Outcome; Human

2014
Alternative treatment approach to cerebral toxoplasmosis in HIV/AIDS: experience from a resource-poor setting.
    International journal of STD & AIDS, 2015, Volume: 26, Issue:12

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Clindamycin; Female; Huma

2015
Failure of conventional treatment with pyrimethamine and sulfadiazine for secondary prophylaxis of cerebral toxoplasmosis in a patient with AIDS.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Antiprotozoal Agents; CD4 Lymphocyte Cou

2011
[Disseminated cerebral haemorrhages in a patient with HIV infection].
    Enfermedades infecciosas y microbiologia clinica, 2011, Volume: 29, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiprotozoal Agents; Antiretroviral

2011
Sulphadiazine-induced obstructive renal failure complicating treatment of HIV-associated toxoplasmosis.
    International journal of STD & AIDS, 2012, Volume: 23, Issue:3

    Topics: Antiprotozoal Agents; Fluid Therapy; HIV Infections; Humans; Middle Aged; Nephrostomy, Percutaneous;

2012
A healthy, 81-year-old woman with toxoplasmic encephalitis.
    Geriatrics & gerontology international, 2012, Volume: 12, Issue:4

    Topics: Aged, 80 and over; Antiprotozoal Agents; Diagnosis, Differential; Female; Humans; Pyrimethamine; Sul

2012
Sulphadiazine-induced renal stones in a 63-year-old HIV-infected man treated for toxoplasmosis.
    BMJ case reports, 2012, Sep-21, Volume: 2012

    Topics: AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Diagnosis, Differential; HIV-1; Humans;

2012
Neurologic outcomes and adjunctive steroids in HIV patients with severe cerebral toxoplasmosis.
    Neurology, 2012, Oct-23, Volume: 79, Issue:17

    Topics: Adult; Antiprotozoal Agents; Comorbidity; Disease Progression; Drug Therapy, Combination; Female; Gl

2012
A solitary brain lesion in a patient with AIDS.
    The AIDS reader, 2003, Volume: 13, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Drug Therapy, Combination; Femal

2003
Treatment of Toxoplasma brain abscess with clindamycin and sulfadiazine in an AIDS patient with concurrent atypical Pneumocystis carinii pneumonia.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2002, Volume: 101, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Brain Abscess; Clindamycin; Drug Therapy, Combination;

2002
Sulfadiazine-induced nephrolithiasis detected by spiral CT scan.
    Delaware medical journal, 2004, Volume: 76, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Humans; Male; Sulfadiazine; Tomography, X-Ray Computed

2004
Atovaquone maintenance therapy prevents reactivation of toxoplasmic encephalitis in a murine model of reactivated toxoplasmosis.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:12

    Topics: Animals; Antiprotozoal Agents; Atovaquone; Brain; Brain Chemistry; Chromatography, High Pressure Liq

2004
Cerebral toxoplasmosis in a patient with common variable immunodeficiency.
    Neurology, 2004, Dec-14, Volume: 63, Issue:11

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Protozoan; Antiprotozoal Agents; Biopsy; Brain; Central N

2004
[Postnatal follow-up of infants born to mothers with certain Toxoplasma gondii infection: evaluation of prenatal management].
    Le infezioni in medicina, 2005, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Amniocentesis; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Chorioretini

2005
[Renal failure caused by sulfadiazine in a HIV patient with toxoplasmic encephalitis].
    Anales de medicina interna (Madrid, Spain : 1984), 2005, Volume: 22, Issue:8

    Topics: Adult; Antiprotozoal Agents; Encephalitis; Female; HIV Infections; Humans; Sulfadiazine; Toxoplasmos

2005
The case: 69 year old man with sand in the urine. N-acetylsulfadiazine crystals.
    Kidney international, 2007, Volume: 72, Issue:6

    Topics: Acute Kidney Injury; Aged; Crystallization; Humans; Male; Sulfadiazine; Tomography, X-Ray Computed;

2007
The timing of sulfadiazine therapy impacts the reactivation of latent Toxoplasma infection in IRF-8-/- mice.
    Parasitology research, 2007, Volume: 101, Issue:6

    Topics: Animals; Antiprotozoal Agents; Brain; Disease Models, Animal; Drug Administration Schedule; Humans;

2007
[Acute renal failure due to sulfadiazine crystalluria].
    Anales de medicina interna (Madrid, Spain : 1984), 2007, Volume: 24, Issue:5

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Alkalies; Animals; Antiprotozoal

2007
Treating AIDS-associated cerebral toxoplasmosis - pyrimethamine plus sulfadiazine compared with cotrimoxazole, and outcome with adjunctive glucocorticoids.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2007, Volume: 97, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antiprotozoal Agents; Drug Ther

2007
Drug treatment of toxoplasmic encephalitis in acquired immunodeficiency syndrome.
    Postgraduate medical journal, 1995, Volume: 71, Issue:837

    Topics: AIDS-Related Opportunistic Infections; Atovaquone; Clindamycin; Coccidiostats; Humans; Naphthoquinon

1995
Toxoplasmosis in AIDS: keeping the lid on.
    Annals of internal medicine, 1995, Aug-01, Volume: 123, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Drug Therapy, Combination; Encephalitis; Humans; Pyrimethamin

1995
[Pyrimethamine-sulfadiazine resistant cerebral toxoplasmosis in AIDS].
    Deutsche medizinische Wochenschrift (1946), 1995, May-26, Volume: 120, Issue:21

    Topics: Acquired Immunodeficiency Syndrome; Animals; Drug Resistance; Drug Therapy, Combination; Humans; Pyr

1995
[Pyrimethamine-sulfadiazine resistant cerebral toxoplasmosis in AIDS].
    Deutsche medizinische Wochenschrift (1946), 1995, Jan-20, Volume: 120, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Clindamycin; Dexamethasone; Drug Resistance, Microbial; Drug

1995
Sulfadiazine/N4-acetylsulfadiazine crystalluria in a patient with the acquired immune deficiency syndrome (AIDS)
    Clinica chimica acta; international journal of clinical chemistry, 1994, Oct-31, Volume: 230, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Hemophilia A; Huma

1994
Persistent enhancement after treatment for cerebral toxoplasmosis in patients with AIDS: predictive value for subsequent recurrence.
    AJNR. American journal of neuroradiology, 1994, Volume: 15, Issue:9

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Atrophy; Brain; Brain Abscess; Drug Therapy, Com

1994
Cataplexy associated with midbrain lesion.
    Neurology, 1995, Volume: 45, Issue:2

    Topics: Adult; AIDS-Related Opportunistic Infections; Cataplexy; HIV Seropositivity; Humans; Magnetic Resona

1995
Renal alterations induced by sulfadiazine therapy in an AIDS patients.
    Clinical nephrology, 1994, Volume: 42, Issue:1

    Topics: Adult; AIDS-Related Opportunistic Infections; Drug Therapy, Combination; Female; Humans; Kidney Calc

1994
[Sulfadiazine nephrolithiasis and nephropathy].
    Schweizerische medizinische Wochenschrift, 1994, Nov-19, Volume: 124, Issue:46

    Topics: Adult; AIDS-Related Opportunistic Infections; Bicarbonates; Fluid Therapy; HIV Infections; Humans; H

1994
Toxoplasma gondii infection in advanced HIV infection.
    AIDS (London, England), 1994, Volume: 8, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Encephalitis; Female; Humans; Male; Middle Ag

1994
[Therapeutic alternatives for cases of cerebral toxoplasmosis in patients with AIDS: clarithromycin and atovaquone].
    Enfermedades infecciosas y microbiologia clinica, 1994, Volume: 12, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Atovaquone; Clarithromycin; Clindamycin; Drug

1994
[Recurrence of cerebral toxoplasmosis in 15 AIDS patients].
    Annales de medecine interne, 1994, Volume: 145, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Brain; Clindamycin; Drug Therapy, Combination; Female;

1994
Rifabutin is active in murine models of toxoplasmosis.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3

    Topics: Animals; Antiprotozoal Agents; Atovaquone; Brain; Clindamycin; Drug Therapy, Combination; Female; Mi

1994
Normal fetal outcome in a pregnancy with central nervous system toxoplasmosis and human immunodeficiency virus infection. A case report.
    The Journal of reproductive medicine, 1993, Volume: 38, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Antibodies, Protozoan; Drug Hypersensitivity;

1993
[Drug-induced Stevens-Johnson syndrome in a patient with AIDS].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1993, Aug-17, Volume: 82, Issue:33

    Topics: Acquired Immunodeficiency Syndrome; Humans; Male; Middle Aged; Phenytoin; Pyrimethamine; Stevens-Joh

1993
[Cerebral toxoplasmosis in AIDS. 73 cases. Clinical Epidemiology Group on AIDS in Aquitania].
    Presse medicale (Paris, France : 1983), 1993, May-29, Volume: 22, Issue:19

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Clarithromycin; Cl

1993
[Acquired cerebral toxoplasmosis in an non-immunosuppressed child].
    Archives francaises de pediatrie, 1993, Volume: 50, Issue:4

    Topics: Child, Preschool; Drug Therapy, Combination; Female; Humans; Immunocompetence; Magnetic Resonance Im

1993
Renal failure due to sulphadiazine in AIDS patients with cerebral toxoplasmosis.
    Journal of internal medicine, 1993, Volume: 233, Issue:4

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Crystallization; Humans; Male; Su

1993
Two central nervous system infectious diseases in a patient with AIDS.
    The Journal of family practice, 1993, Volume: 36, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Hu

1993
Symptomatic sulfadiazine crystalluria in AIDS patients: a report of two cases.
    Clinical nephrology, 1993, Volume: 39, Issue:5

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Drug Therapy, Combination; Humans

1993
Adverse cutaneous reactions to pyrimethamine/sulfadiazine and pyrimethamine/clindamycin in patients with AIDS and toxoplasmic encephalitis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Clindamy

1995
Nonionic block copolymers potentiate activities of drugs for treatment of infections with Toxoplasma gondii.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:12

    Topics: Animals; Anti-Infective Agents; Cytokines; Drug Synergism; Encephalitis; Female; Lymphocyte Activati

1995
Folinic acid supplements to pyrimethamine-sulfadiazine for Toxoplasma encephalitis are associated with better outcome.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:5

    Topics: Antiprotozoal Agents; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Encephalitis;

1996
Resolution of intracranial calcifications in infants with treated congenital toxoplasmosis.
    Radiology, 1996, Volume: 199, Issue:2

    Topics: Anti-Infective Agents; Brain; Calcinosis; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leucov

1996
[Cerebral toxoplasmosis in patients with human immunodeficiency virus (HIV) infection. Clinico-radiological and therapeutic aspects in 63 patients].
    Anales de medicina interna (Madrid, Spain : 1984), 1996, Volume: 13, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Clind

1996
[Acute renal insufficiency caused by a sulfadiazine in a patient with cerebral toxoplasmosis and AIDS].
    Enfermedades infecciosas y microbiologia clinica, 1996, Volume: 14, Issue:2

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Humans; Ki

1996
Precipitous visual loss secondary to optic nerve toxoplasmosis as an unusual presentation of AIDS.
    Australian and New Zealand journal of ophthalmology, 1996, Volume: 24, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Drug Therap

1996
Sulfadiazine-induced multiple urolithiasis and acute renal failure in a patient with AIDS and Toxoplasma encephalitis.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:1

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Crystalliz

1996
Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; Brain; Clin

1996
Choreoathetosis in acquired immune deficiency syndrome patients with cerebral toxoplasmosis.
    Movement disorders : official journal of the Movement Disorder Society, 1996, Volume: 11, Issue:4

    Topics: Adult; AIDS Dementia Complex; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Athetosi

1996
Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients.
    International journal of STD & AIDS, 1996, Volume: 7, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal

1996
Acute renal failure due to sulphadiazine crystalluria in AIDS patients.
    Postgraduate medical journal, 1996, Volume: 72, Issue:851

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Crystalliz

1996
Renal ultrasonic findings in sulphadiazine-induced renal failure.
    The British journal of radiology, 1996, Volume: 69, Issue:826

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Crystallization; Humans; Male; Mi

1996
A clinical-parasitological monotherapy cure in the treatment of experimental infection by a highly virulent strain of Toxoplasma gondii.
    Folia microbiologica, 1996, Volume: 41, Issue:6

    Topics: Animals; Antiprotozoal Agents; Brain; Drug Evaluation, Preclinical; Drug Therapy, Combination; Mice;

1996
Penetration of 3'-amino-3'-deoxythymidine, a cytotoxic metabolite of zidovudine, into the cerebrospinal fluid of HIV-1-infected patients.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Jun-01, Volume: 15, Issue:2

    Topics: Administration, Oral; Adult; Anti-HIV Agents; Anti-Infective Agents; Antidotes; Dideoxynucleosides;

1997
[HIV infection and Lyell syndrome: a wake-up call concerning anti-inflammatory agents].
    Enfermedades infecciosas y microbiologia clinica, 1997, Volume: 15, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory

1997
Toxoplasma encephalitis in a HIV patient: unusual involvement of the corpus callosum.
    Clinical neurology and neurosurgery, 1997, Volume: 99, Issue:4

    Topics: Adult; Animals; Anti-Infective Agents; Brain Neoplasms; Corpus Callosum; Diagnosis, Differential; En

1997
[Cerebral toxoplasmosis and AIDS in Martinique].
    Medecine tropicale : revue du Corps de sante colonial, 1997, Volume: 57, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Drug Therapy, Combination; Fema

1997
Neuropsychiatric lupus?
    Annals of the rheumatic diseases, 1998, Volume: 57, Issue:1

    Topics: Anti-Infective Agents; Antibodies, Protozoan; Drug Therapy, Combination; Humans; Lupus Erythematosus

1998
Toxoplasma retinitis/encephalitis 9 months after allogeneic bone marrow transplantation.
    Bone marrow transplantation, 1998, Volume: 21, Issue:6

    Topics: Adult; Anti-Infective Agents; Bone Marrow Transplantation; Clindamycin; Female; Graft vs Host Diseas

1998
[Desensitization with sulfadiazine in a patient with cerebral toxoplasmosis refractory to alternative treatment].
    Enfermedades infecciosas y microbiologia clinica, 1998, Volume: 16, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Desensitization, Immunologic; Drug Eruptions;

1998
[Acute encephalopathy caused by sulfadiazine and trimethoprim-sulfamethoxazole in a patient with AIDS].
    Enfermedades infecciosas y microbiologia clinica, 1998, Volume: 16, Issue:5

    Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Brain Neoplasms;

1998
Post-transplant cerebral toxoplasmosis diagnosed by magnetic resonance imaging.
    Haematologica, 1998, Volume: 83, Issue:6

    Topics: Adult; Anti-Infective Agents; Bone Marrow Transplantation; Hodgkin Disease; Humans; Male; Pyrimetham

1998
Determination of the inhibitory effect on Toxoplasma growth in the serum of AIDS patients during acute therapy for toxoplasmic encephalitis.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Sep-01, Volume: 19, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dr

1998
Fatal Stevens-Johnson syndrome in an AIDS patient treated with sulfadiazine.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiprotozoal Agents; Fatal Outcome; Humans; Male; Steven

1999
Obstructive nephropathy due to sulfa crystals in two HIV seropositive patients treated with sulfadiazine.
    JBR-BTR : organe de la Societe royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR), 1999, Volume: 82, Issue:4

    Topics: AIDS-Related Opportunistic Infections; Alkalies; Antiprotozoal Agents; Crystallization; Female; Flui

1999
Toxoplasmosis, a severe complication in allogeneic hematopoietic stem cell transplantation: successful treatment strategies during a 5-year single-center experience.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Volume: 32, Issue:1

    Topics: Adult; Animals; Antibodies, Protozoan; Clindamycin; Drug Therapy, Combination; Female; Hematopoietic

2001
[Kidney failure caused by sulphadiazine in patients with toxoplasma encephalitis].
    Anales de medicina interna (Madrid, Spain : 1984), 2000, Volume: 17, Issue:11

    Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Encephaliti

2000
[Toxoplasma encephalitis in a previously healthy man].
    Duodecim; laaketieteellinen aikakauskirja, 1999, Volume: 115, Issue:3

    Topics: Abattoirs; Antiprotozoal Agents; Drug Therapy, Combination; Encephalitis; Humans; Male; Middle Aged;

1999
Empiric treatment of acute Toxoplasma encephalitis in patients with acquired immunodeficiency syndrome.
    Archives of internal medicine, 1992, Volume: 152, Issue:10

    Topics: AIDS-Related Opportunistic Infections; Encephalitis; Humans; Pyrimethamine; Sulfadiazine; Toxoplasmo

1992
Encephalopathy and psychoses associated with sulfadiazine in two patients with AIDS and CNS toxoplasmosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 15, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Humans; Male; Psychoses, Substance-Induced; Sulfadiazine;

1992
[Acute renal failure caused by sulfadiazine crystalluria in AIDS. An historical resurgent iatrogenic complication].
    Annales de medecine interne, 1992, Volume: 143, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adult; Humans; Iatrogenic Disease; Male; Op

1992
Transitory alexia without agraphia in an HIV-positive patient suffering from toxoplasma encephalitis: a case report.
    European neurology, 1992, Volume: 32, Issue:1

    Topics: Adult; Agraphia; Drug Therapy, Combination; Dyslexia, Acquired; HIV Seropositivity; Humans; Leucovor

1992
[Acute kidney failure due to sulfadiazine in the treatment of cerebral toxoplasmosis].
    Revista clinica espanola, 1992, Volume: 190, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; HIV-1; Humans; Male; Middle Aged; Opportuni

1992
Pyrimethamine alone as maintenance therapy for central nervous system toxoplasmosis in 38 patients with AIDS.
    Journal of acquired immune deficiency syndromes, 1992, Volume: 5, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Therapy, Combination; Female; Humans; Male; Opportun

1992
Sulphadiazine desensitization in AIDS patients.
    AIDS (London, England), 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Desensitization, Immunologic; Female; Humans; Male; Sulfadiazine

1991