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sulfadiazine and Central Nervous System Diseases

sulfadiazine has been researched along with Central Nervous System Diseases in 13 studies

Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
sulfadiazine : A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.
diazine : The parent structure of the diazines.

Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.

Research Excerpts

ExcerptRelevanceReference
"Thirty-five patients with the acquired immunodeficiency syndrome (AIDS) and central nervous system toxoplasmosis, seen over a 30-month period, were treated with the combination pyrimethamine/sulfadiazine."7.67Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy. ( Katlama, C; Leport, C; Marche, C; Matheron, S; Raffi, F; Regnier, B; Saimot, AG; Vedrenne, C; Vilde, JL, 1988)
"Three patients with acquired immune deficiency syndrome (AIDS), central nervous system toxoplasmosis, and hypersensitivity to sulfadiazine were given treatment with clindamycin plus pyrimethamine."7.67Role of clindamycin in the treatment of central nervous system toxoplasmosis. ( Hoy, J; Rolston, KV, 1987)
"We retrospectively examined 39 patients with AIDS and central nervous system toxoplasmosis in order to determine the efficacy and safety of two combinations: pyrimethamine-sulfadiazine and pyrimethamine-clindamycin."5.07Comparison of two medications in central nervous system toxoplasmosis in patients with AIDS. ( Ammassari, A; Antinori, A; Camilli, G; Damiano, F; Federico, G; Maiuro, G; Pizzigallo, E; Tamburrini, E, 1992)
"Thirty-five patients with the acquired immunodeficiency syndrome (AIDS) and central nervous system toxoplasmosis, seen over a 30-month period, were treated with the combination pyrimethamine/sulfadiazine."3.67Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy. ( Katlama, C; Leport, C; Marche, C; Matheron, S; Raffi, F; Regnier, B; Saimot, AG; Vedrenne, C; Vilde, JL, 1988)
"Three patients with acquired immune deficiency syndrome (AIDS), central nervous system toxoplasmosis, and hypersensitivity to sulfadiazine were given treatment with clindamycin plus pyrimethamine."3.67Role of clindamycin in the treatment of central nervous system toxoplasmosis. ( Hoy, J; Rolston, KV, 1987)
"Early detection and treatment of congenital toxoplasmosis may reduce these sequelae."1.29Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection. The New England Regional Toxoplasma Working Group. ( Abroms, I; Eaton, RB; Guerina, NG; Hoff, R; Hsu, HW; Lynfield, R; Maguire, JH; Meissner, HC; Pasternack, MS; Stechenberg, B, 1994)
"Forty-two cases of Toxoplasma gondii infection were analyzed, 25 in patients with neoplastic disease and 17 in apparently normal patients."1.27Toxoplasmosis. Problems in diagnosis and treatment. ( Armstrong, D; Hakes, TB, 1983)
"Toxoplasmosis is usually an asymptomatic infection, but symptomatic cases are becoming more common with the rise in AIDS cases and the increased number of patients receiving immunosuppressive therapy."1.27Toxoplasmosis of the central nervous system. ( Meredith, JT, 1987)
"Previously, CNS-toxoplasmosis has been noted to complicate lymphomas after initiation of anti-neoplastic therapy."1.26Favorable outcome of central nervous system toxoplasmosis occurring in a patient with untreated Hodgkin's disease. ( Cheson, BD; Green, JA; Spruance, SL, 1980)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19908 (61.54)18.7374
1990's4 (30.77)18.2507
2000's0 (0.00)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stack, A1
Schott, HC1
ANDRIOLE, VT1
BALLAS, M1
WILSON, GL1
Hakes, TB1
Armstrong, D1
Green, JA1
Spruance, SL1
Cheson, BD1
Guerina, NG1
Hsu, HW1
Meissner, HC1
Maguire, JH1
Lynfield, R1
Stechenberg, B1
Abroms, I1
Pasternack, MS1
Hoff, R1
Eaton, RB1
Antinori, A1
Ammassari, A1
Maiuro, G1
Camilli, G1
Damiano, F1
Federico, G1
Pizzigallo, E1
Tamburrini, E1
Mitchell, CD1
Erlich, SS1
Mastrucci, MT1
Hutto, SC1
Parks, WP1
Scott, GB1
Pedrol, E1
González-Clemente, JM1
Gatell, JM1
Mallolas, J1
Miró, JM1
Graus, F1
Alvarez, R1
Mercader, JM1
Berenguer, J1
Jiménez de Anta, MT1
Leport, C1
Raffi, F1
Matheron, S1
Katlama, C1
Regnier, B1
Saimot, AG1
Marche, C1
Vedrenne, C1
Vilde, JL1
Meredith, JT1
Rolston, KV1
Hoy, J1
Richter, RW1
Silva, M1
Neu, HC1
Silverstein, PM1
Dumas, M1
N'Diaye, IP1
Girard, PL1

Trials

1 trial available for sulfadiazine and Central Nervous System Diseases

ArticleYear
Comparison of two medications in central nervous system toxoplasmosis in patients with AIDS.
    Italian journal of neurological sciences, 1992, Volume: 13, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Central Nervous System Diseases; Clindamycin; Drug Combinations;

1992

Other Studies

12 other studies available for sulfadiazine and Central Nervous System Diseases

ArticleYear
Suspect novel adverse drug reactions to trimethoprim-sulphonamide combinations in horses: a case series.
    Equine veterinary journal, 2011, Volume: 43, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Central Nervous System Diseases; Drug Overdose; Drug Therapy, Combin

2011
THE ASSOCIATION OF NOCARDIOSIS AND PULMONARY ALVEOLAR PROTEINOSIS. A CASE STUDY.
    Annals of internal medicine, 1964, Volume: 60

    Topics: Brain Abscess; Candidiasis; Central Nervous System Diseases; Humans; Iodides; Nocardia Infections; P

1964
Toxoplasmosis. Problems in diagnosis and treatment.
    Cancer, 1983, Oct-15, Volume: 52, Issue:8

    Topics: Adolescent; Adult; Central Nervous System Diseases; Drug Therapy, Combination; Female; Hodgkin Disea

1983
Favorable outcome of central nervous system toxoplasmosis occurring in a patient with untreated Hodgkin's disease.
    Cancer, 1980, Feb-15, Volume: 45, Issue:4

    Topics: Adult; Antineoplastic Agents; Central Nervous System Diseases; Drug Therapy, Combination; Hodgkin Di

1980
Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection. The New England Regional Toxoplasma Working Group.
    The New England journal of medicine, 1994, Jun-30, Volume: 330, Issue:26

    Topics: Antibodies, Protozoan; Central Nervous System Diseases; Follow-Up Studies; Humans; Immunoglobulin G;

1994
Congenital toxoplasmosis occurring in infants perinatally infected with human immunodeficiency virus 1.
    The Pediatric infectious disease journal, 1990, Volume: 9, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Animals; Central Nervous System Diseases; Family Health; Female;

1990
Central nervous system toxoplasmosis in AIDS patients: efficacy of an intermittent maintenance therapy.
    AIDS (London, England), 1990, Volume: 4, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Central Nervous System Diseases; Clindamycin; Drug Combinations;

1990
Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy.
    The American journal of medicine, 1988, Volume: 84, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Central Nervous System Diseases; Drug Therapy, Combinatio

1988
Toxoplasmosis of the central nervous system.
    American family physician, 1987, Volume: 35, Issue:5

    Topics: Adult; Central Nervous System Diseases; Cerebellum; Encephalitis; Female; Humans; Pyrimethamine; Sul

1987
Role of clindamycin in the treatment of central nervous system toxoplasmosis.
    The American journal of medicine, 1987, Volume: 83, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Central Nervous System Diseases; Clindamycin; Drug Therap

1987
The neurological aspects of Nocardia asteroides infection.
    Research publications - Association for Research in Nervous and Mental Disease, 1968, Volume: 44

    Topics: Adult; Brain; Brain Abscess; Central Nervous System Diseases; Drainage; Female; Humans; Long-Term Ca

1968
[Nervous system mycoses in Senegal].
    The African journal of medical sciences, 1973, Volume: 4, Issue:2

    Topics: Adult; Black or African American; Black People; Brain Abscess; Brain Diseases; Carotid Arteries; Cen

1973