sulfadiazine has been researched along with Brain Inflammation in 47 studies
Sulfadiazine: One of the short-acting SULFONAMIDES used in combination with PYRIMETHAMINE to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
sulfadiazine : A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position.
diazine : The parent structure of the diazines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The preferred therapeutic regimen for Toxoplasma encephalitis (TE) is a combination of pyrimethamine and sulfadiazine, and trimethoprim-sulfamethoxazole (TMP-SMX) plus azithromycin is the widespread alternative therapeutic regimen." | 9.51 | Synergistic sulfonamides plus clindamycin as an alternative therapeutic regimen for HIV-associated Toxoplasma encephalitis: a randomized controlled trial. ( Chen, H; Chen, Y; He, X; Huang, Y; Li, Y; Lu, Y; Wu, Y; Zeng, Y; Zhang, W, 2022) |
| "In this international, noncomparative, randomized phase II trial, we evaluated the effectiveness and tolerance of atovaquone suspension (1500 mg orally twice daily) plus either pyrimethamine (75 mg per day after a 200-mg loading dose) or sulfadiazine (1500 mg 4 times daily) as treatment for acute disease (for 6 weeks) and as maintenance therapy (for 42 weeks) for toxoplasmic encephalitis (TE) in patients infected with human immunodeficiency virus." | 9.10 | Randomized phase II trial of atovaquone with pyrimethamine or sulfadiazine for treatment of toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome: ACTG 237/ANRS 039 Study. AIDS Clinical Trials Group 237/Agence Nationale de Recherche ( Andersen, J; Bosler, EM; Chirgwin, K; Hafner, R; Jayaweera, DT; Leport, C; Luft, BJ; McAuliffe, V; Morlat, P; Rajicic, N; Remington, J; Roque, C; Vilde, JL, 2002) |
| "An open, randomised, multicentre trial was conducted to evaluate the efficacy of thrice-weekly versus daily therapy with sulfadiazine-pyrimethamine in the prevention of relapses of toxoplasmic encephalitis in HIV-infected patients." | 9.09 | Thrice-weekly sulfadiazine-pyrimethamine for maintenance therapy of toxoplasmic encephalitis in HIV-infected patients. Spanish Toxoplasmosis Study Group. ( Arrizabalaga, J; Cosin, J; Cruceta, A; Domingo, P; Fariñas, MC; Ferrer, E; Gatell, JM; Gudiol, F; Knobel, H; Leyes, M; Martínez-Lacasa, J; Miró, JM; Podzamczer, D; Polo, R; Ramón, JM; Ribera, E; Sirera, G, 2000) |
| "This European multicenter study compares the efficacy and tolerance of the combination of pyrimethamine-clindamycin (Pyr-Cm) with the standard therapy pyrimethamine-sulfadiazine (Pyr-Sdz) for the treatment of toxoplasmic encephalitis (TE) in patients with AIDS." | 9.08 | Pyrimethamine-clindamycin vs. pyrimethamine-sulfadiazine as acute and long-term therapy for toxoplasmic encephalitis in patients with AIDS. ( Clumeck, N; De Wit, S; Katlama, C; O'Doherty, E; Van Glabeke, M, 1996) |
| "To evaluate the efficacy of twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent toxoplasmic encephalitis relapse in patients with the acquired immunodeficiency syndrome (AIDS)." | 9.08 | Twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent recurrent toxoplasmic encephalitis in patients with AIDS. Spanish Toxoplasmosis Study Group. ( Bolao, F; Cosín, J; Domingo, P; Gatell, JM; Laguna, F; Miró, JM; Podzamczer, D; Santamaría, J; Sirera, G; Verdejo, J, 1995) |
| "The aim of the present pilot study was to compare the efficacy and safety of trimethoprim (TMP) and sulfamethoxazole (SMX) with those of the standard therapy pyrimethamine (P)-sulfadiazine (S) for the treatment of toxoplasmic encephalitis in patients with AIDS." | 9.08 | Randomized trial of trimethoprim-sulfamethoxazole versus pyrimethamine-sulfadiazine for therapy of toxoplasmic encephalitis in patients with AIDS. Italian Collaborative Study Group. ( Angarano, G; Carosi, G; Casari, S; Chiodo, F; Donisi, A; Fiori, G; Gregis, G; Orani, A; Poggio, A; Ranieri, S; Speranza, F; Torre, D, 1998) |
| "Sixty-five patients intolerant of conventional toxoplasmic encephalitis therapies-pyrimethamine, sulphadiazine or clindamycin-received atovaquone as maintenance therapy after resolution of an acute episode of toxoplasmic encephalitis." | 9.08 | Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group. ( Gourdon, D; Katlama, C; Lapierre, D; Mouthon, B; Rousseau, F, 1996) |
| "A prospective study was conducted to evaluate azithromycin in combination with pyrimethamine for treatment of acute Toxoplasma encephalitis in patients with AIDS." | 9.07 | Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. ( Hazebroucq, V; Joly, V; Leport, C; Morlat, P; Raffi, F; Saba, J; Vildé, JL, 1993) |
| "To compare pyrimethamine plus clindamycin (PC) to pyrimethamine plus sulfadiazine (PS) as a treatment for toxoplasmic encephalitis (TE) in patients with the acquired immunodeficiency syndrome (AIDS)." | 9.07 | Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group. ( Antoniskis, D; Chiu, J; Clumeck, N; Dannemann, B; Israelski, D; Leport, C; Luft, B; McCutchan, JA; Morlat, P; Nussbaum, J, 1992) |
| "The interim results are presented of an ongoing large-scale, prospective, randomized study to determine the potential role of clindamycin in the treatment of toxoplasmic encephalitis." | 9.07 | Treatment of acute toxoplasmosis with intravenous clindamycin. The California Collaborative Treatment Group. ( Antoniskis, D; Chiu, J; Dannemann, BR; Israelski, DM; Leport, C; Luft, BJ; McCutchan, JA; Nussbaum, JN; Orellana, M; Vildé, JL, 1991) |
| " The standard treatment for toxoplasmic encephalitis is pyrimethamine and sulfadiazine." | 7.71 | Treatment of Toxoplasma brain abscess with clindamycin and sulfadiazine in an AIDS patient with concurrent atypical Pneumocystis carinii pneumonia. ( Chen, ER; Chen, YS; Huang, CK; Lee, SS; Lin, HH; Lin, WR; Liu, YC; Tsai, HC, 2002) |
| "A patient with AIDS who was being treated with pyrimethamine and sulfadiazine for Toxoplasma encephalitis developed lumbar pain, dysuria, urinary frequency, and hematuria." | 7.69 | Sulfadiazine-induced multiple urolithiasis and acute renal failure in a patient with AIDS and Toxoplasma encephalitis. ( Collazos, J; Díaz, F; Martínez, E; Mayo, J, 1996) |
| "The effectiveness of combinations of rifabutin with atovaquone, clindamycin, pyrimethamine, or sulfadiazine in the treatment of toxoplasmic encephalitis in a murine model was investigated." | 7.69 | Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice. ( Araujo, FG; Remington, JS; Suzuki, Y, 1996) |
| " Provided prophylactic and therapeutic recommendations are complied with, outcome of this drug-related side effect is usually excellent, and rare relapses will similarly respond well." | 6.39 | Sulfadiazine-associated nephrotoxicity in patients with the acquired immunodeficiency syndrome. ( Becker, K; Häussinger, D; Jablonowski, H, 1996) |
| "Toxoplasma gondii encephalitis is an important opportunistic infection in the acquired immunodeficiency syndrome, estimated to occur in 20,000 to 40,000 patients with acquired immunodeficiency syndrome in the United States by 1991." | 6.38 | Sulfadiazine crystalluria revisited. The treatment of Toxoplasma encephalitis in patients with acquired immunodeficiency syndrome. ( Brosius, FC; Rothstein, DM; Simon, DI, 1990) |
| "The preferred therapeutic regimen for Toxoplasma encephalitis (TE) is a combination of pyrimethamine and sulfadiazine, and trimethoprim-sulfamethoxazole (TMP-SMX) plus azithromycin is the widespread alternative therapeutic regimen." | 5.51 | Synergistic sulfonamides plus clindamycin as an alternative therapeutic regimen for HIV-associated Toxoplasma encephalitis: a randomized controlled trial. ( Chen, H; Chen, Y; He, X; Huang, Y; Li, Y; Lu, Y; Wu, Y; Zeng, Y; Zhang, W, 2022) |
| "Toxoplasma encephalitis is the most common opportunistic infection of the central nervous system in patients with AIDS." | 5.28 | Sulfadiazine-induced crystalluria in AIDS patients with toxoplasma encephalitis. ( Belenfant, X; Doco-Lecompte, T; Idatte, JM; Modai, J; Molina, JM, 1991) |
| "In this international, noncomparative, randomized phase II trial, we evaluated the effectiveness and tolerance of atovaquone suspension (1500 mg orally twice daily) plus either pyrimethamine (75 mg per day after a 200-mg loading dose) or sulfadiazine (1500 mg 4 times daily) as treatment for acute disease (for 6 weeks) and as maintenance therapy (for 42 weeks) for toxoplasmic encephalitis (TE) in patients infected with human immunodeficiency virus." | 5.10 | Randomized phase II trial of atovaquone with pyrimethamine or sulfadiazine for treatment of toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome: ACTG 237/ANRS 039 Study. AIDS Clinical Trials Group 237/Agence Nationale de Recherche ( Andersen, J; Bosler, EM; Chirgwin, K; Hafner, R; Jayaweera, DT; Leport, C; Luft, BJ; McAuliffe, V; Morlat, P; Rajicic, N; Remington, J; Roque, C; Vilde, JL, 2002) |
| "An open, randomised, multicentre trial was conducted to evaluate the efficacy of thrice-weekly versus daily therapy with sulfadiazine-pyrimethamine in the prevention of relapses of toxoplasmic encephalitis in HIV-infected patients." | 5.09 | Thrice-weekly sulfadiazine-pyrimethamine for maintenance therapy of toxoplasmic encephalitis in HIV-infected patients. Spanish Toxoplasmosis Study Group. ( Arrizabalaga, J; Cosin, J; Cruceta, A; Domingo, P; Fariñas, MC; Ferrer, E; Gatell, JM; Gudiol, F; Knobel, H; Leyes, M; Martínez-Lacasa, J; Miró, JM; Podzamczer, D; Polo, R; Ramón, JM; Ribera, E; Sirera, G, 2000) |
| "To evaluate the efficacy of twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent toxoplasmic encephalitis relapse in patients with the acquired immunodeficiency syndrome (AIDS)." | 5.08 | Twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent recurrent toxoplasmic encephalitis in patients with AIDS. Spanish Toxoplasmosis Study Group. ( Bolao, F; Cosín, J; Domingo, P; Gatell, JM; Laguna, F; Miró, JM; Podzamczer, D; Santamaría, J; Sirera, G; Verdejo, J, 1995) |
| "This European multicenter study compares the efficacy and tolerance of the combination of pyrimethamine-clindamycin (Pyr-Cm) with the standard therapy pyrimethamine-sulfadiazine (Pyr-Sdz) for the treatment of toxoplasmic encephalitis (TE) in patients with AIDS." | 5.08 | Pyrimethamine-clindamycin vs. pyrimethamine-sulfadiazine as acute and long-term therapy for toxoplasmic encephalitis in patients with AIDS. ( Clumeck, N; De Wit, S; Katlama, C; O'Doherty, E; Van Glabeke, M, 1996) |
| "Sixty-five patients intolerant of conventional toxoplasmic encephalitis therapies-pyrimethamine, sulphadiazine or clindamycin-received atovaquone as maintenance therapy after resolution of an acute episode of toxoplasmic encephalitis." | 5.08 | Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group. ( Gourdon, D; Katlama, C; Lapierre, D; Mouthon, B; Rousseau, F, 1996) |
| "The aim of the present pilot study was to compare the efficacy and safety of trimethoprim (TMP) and sulfamethoxazole (SMX) with those of the standard therapy pyrimethamine (P)-sulfadiazine (S) for the treatment of toxoplasmic encephalitis in patients with AIDS." | 5.08 | Randomized trial of trimethoprim-sulfamethoxazole versus pyrimethamine-sulfadiazine for therapy of toxoplasmic encephalitis in patients with AIDS. Italian Collaborative Study Group. ( Angarano, G; Carosi, G; Casari, S; Chiodo, F; Donisi, A; Fiori, G; Gregis, G; Orani, A; Poggio, A; Ranieri, S; Speranza, F; Torre, D, 1998) |
| "A prospective study was conducted to evaluate azithromycin in combination with pyrimethamine for treatment of acute Toxoplasma encephalitis in patients with AIDS." | 5.07 | Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. ( Hazebroucq, V; Joly, V; Leport, C; Morlat, P; Raffi, F; Saba, J; Vildé, JL, 1993) |
| "To compare pyrimethamine plus clindamycin (PC) to pyrimethamine plus sulfadiazine (PS) as a treatment for toxoplasmic encephalitis (TE) in patients with the acquired immunodeficiency syndrome (AIDS)." | 5.07 | Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group. ( Antoniskis, D; Chiu, J; Clumeck, N; Dannemann, B; Israelski, D; Leport, C; Luft, B; McCutchan, JA; Morlat, P; Nussbaum, J, 1992) |
| "The interim results are presented of an ongoing large-scale, prospective, randomized study to determine the potential role of clindamycin in the treatment of toxoplasmic encephalitis." | 5.07 | Treatment of acute toxoplasmosis with intravenous clindamycin. The California Collaborative Treatment Group. ( Antoniskis, D; Chiu, J; Dannemann, BR; Israelski, DM; Leport, C; Luft, BJ; McCutchan, JA; Nussbaum, JN; Orellana, M; Vildé, JL, 1991) |
| " The standard treatment for toxoplasmic encephalitis is pyrimethamine and sulfadiazine." | 3.71 | Treatment of Toxoplasma brain abscess with clindamycin and sulfadiazine in an AIDS patient with concurrent atypical Pneumocystis carinii pneumonia. ( Chen, ER; Chen, YS; Huang, CK; Lee, SS; Lin, HH; Lin, WR; Liu, YC; Tsai, HC, 2002) |
| "In 26 AIDS patients treated for toxoplasmic encephalitis, the inhibitory effect on Toxoxplasma growth of sequential sera taken before and after initiation of therapy was determined using a culture-based immunoassay and compared with pyrimethamine blood levels." | 3.70 | Determination of the inhibitory effect on Toxoplasma growth in the serum of AIDS patients during acute therapy for toxoplasmic encephalitis. ( Derouin, F; Farinotti, R; Gérard, L; Leport, C; Maslo, C, 1998) |
| "The effectiveness of combinations of rifabutin with atovaquone, clindamycin, pyrimethamine, or sulfadiazine in the treatment of toxoplasmic encephalitis in a murine model was investigated." | 3.69 | Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice. ( Araujo, FG; Remington, JS; Suzuki, Y, 1996) |
| "A patient with AIDS who was being treated with pyrimethamine and sulfadiazine for Toxoplasma encephalitis developed lumbar pain, dysuria, urinary frequency, and hematuria." | 3.69 | Sulfadiazine-induced multiple urolithiasis and acute renal failure in a patient with AIDS and Toxoplasma encephalitis. ( Collazos, J; Díaz, F; Martínez, E; Mayo, J, 1996) |
| " Provided prophylactic and therapeutic recommendations are complied with, outcome of this drug-related side effect is usually excellent, and rare relapses will similarly respond well." | 2.39 | Sulfadiazine-associated nephrotoxicity in patients with the acquired immunodeficiency syndrome. ( Becker, K; Häussinger, D; Jablonowski, H, 1996) |
| "Toxoplasma gondii encephalitis is an important opportunistic infection in the acquired immunodeficiency syndrome, estimated to occur in 20,000 to 40,000 patients with acquired immunodeficiency syndrome in the United States by 1991." | 2.38 | Sulfadiazine crystalluria revisited. The treatment of Toxoplasma encephalitis in patients with acquired immunodeficiency syndrome. ( Brosius, FC; Rothstein, DM; Simon, DI, 1990) |
| "Sulfadiazine (SD) is a classic antibiotic for intracranial infection." | 1.42 | The Role of Sulfadiazine for the Treatment of Refractory Intracranial Infection. ( Ding, X; Hu, G; Hu, L; Lu, Y; Zhang, C, 2015) |
| "Toxoplasma encephalitis is the most common opportunistic infection of the central nervous system in patients with AIDS." | 1.28 | Sulfadiazine-induced crystalluria in AIDS patients with toxoplasma encephalitis. ( Belenfant, X; Doco-Lecompte, T; Idatte, JM; Modai, J; Molina, JM, 1991) |
| "Toxoplasmosis is usually an asymptomatic infection, but symptomatic cases are becoming more common with the rise in AIDS cases and the increased number of patients receiving immunosuppressive therapy." | 1.27 | Toxoplasmosis of the central nervous system. ( Meredith, JT, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (17.02) | 18.7374 |
| 1990's | 29 (61.70) | 18.2507 |
| 2000's | 8 (17.02) | 29.6817 |
| 2010's | 1 (2.13) | 24.3611 |
| 2020's | 1 (2.13) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Zeng, Y | 1 |
| Lu, Y | 2 |
| He, X | 1 |
| Wu, Y | 1 |
| Zhang, W | 1 |
| Huang, Y | 1 |
| Chen, H | 1 |
| Chen, Y | 1 |
| Zhang, C | 1 |
| Hu, L | 1 |
| Ding, X | 1 |
| Hu, G | 1 |
| Hill, D | 1 |
| Dubey, JP | 2 |
| Tsai, HC | 1 |
| Lee, SS | 1 |
| Lin, HH | 1 |
| Lin, WR | 1 |
| Chen, YS | 1 |
| Huang, CK | 1 |
| Liu, YC | 1 |
| Chen, ER | 1 |
| Filice, G | 1 |
| Carnevale, G | 1 |
| Orsolini, P | 1 |
| Soldini, L | 1 |
| Meroni, V | 1 |
| Comolli, G | 1 |
| Carenzo, L | 1 |
| Solano Remírez, M | 1 |
| Oliván Ballabriga, AS | 1 |
| da Costa Rodríguez, GM | 1 |
| Alvarez Frías, MT | 1 |
| González Arencibia, C | 1 |
| de la Prada Alvarez, FJ | 1 |
| Prados Gallardo, AM | 1 |
| Tugores Vázquez, A | 1 |
| Uriol Rivera, M | 1 |
| Morey Molina, A | 1 |
| Robinson, RO | 1 |
| Baumann, RJ | 1 |
| Podzamczer, D | 2 |
| Miró, JM | 2 |
| Bolao, F | 1 |
| Gatell, JM | 2 |
| Cosín, J | 2 |
| Sirera, G | 2 |
| Domingo, P | 2 |
| Laguna, F | 1 |
| Santamaría, J | 1 |
| Verdejo, J | 1 |
| Kovacs, JA | 1 |
| Peh, CA | 1 |
| Kimber, TE | 1 |
| Shaw, DR | 1 |
| Clarkson, AR | 1 |
| Oksenhendler, E | 1 |
| Charreau, I | 1 |
| Tournerie, C | 2 |
| Azihary, M | 1 |
| Carbon, C | 1 |
| Aboulker, JP | 1 |
| Saba, J | 1 |
| Morlat, P | 3 |
| Raffi, F | 1 |
| Hazebroucq, V | 1 |
| Joly, V | 1 |
| Leport, C | 6 |
| Vildé, JL | 4 |
| McCabe, R | 1 |
| Chirurgi, V | 1 |
| Caumes, E | 1 |
| Bocquet, H | 1 |
| Guermonprez, G | 1 |
| Rogeaux, O | 1 |
| Bricaire, F | 1 |
| Katlama, C | 4 |
| Gentilini, M | 1 |
| Araujo, FG | 2 |
| Slifer, T | 1 |
| Van Delden, C | 1 |
| Hirschel, B | 1 |
| Becker, K | 1 |
| Jablonowski, H | 1 |
| Häussinger, D | 1 |
| Díaz, F | 1 |
| Collazos, J | 1 |
| Mayo, J | 1 |
| Martínez, E | 1 |
| Suzuki, Y | 2 |
| Remington, JS | 2 |
| De Wit, S | 1 |
| O'Doherty, E | 1 |
| Van Glabeke, M | 1 |
| Clumeck, N | 2 |
| Mouthon, B | 1 |
| Gourdon, D | 1 |
| Lapierre, D | 1 |
| Rousseau, F | 1 |
| Supiot, F | 1 |
| Guillaume, MP | 1 |
| Hermanus, N | 1 |
| Telerman-Toppet, N | 1 |
| Karmali, R | 1 |
| Torre, D | 1 |
| Casari, S | 1 |
| Speranza, F | 1 |
| Donisi, A | 1 |
| Gregis, G | 1 |
| Poggio, A | 1 |
| Ranieri, S | 1 |
| Orani, A | 1 |
| Angarano, G | 1 |
| Chiodo, F | 1 |
| Fiori, G | 1 |
| Carosi, G | 1 |
| Derouin, F | 1 |
| Gérard, L | 1 |
| Farinotti, R | 1 |
| Maslo, C | 1 |
| Ferrer, E | 1 |
| Ramón, JM | 1 |
| Ribera, E | 1 |
| Cruceta, A | 1 |
| Knobel, H | 1 |
| Polo, R | 1 |
| Leyes, M | 1 |
| Fariñas, MC | 2 |
| Arrizabalaga, J | 2 |
| Martínez-Lacasa, J | 1 |
| Gudiol, F | 1 |
| Kang, H | 1 |
| Parmley, S | 1 |
| Lim, S | 1 |
| Park, D | 1 |
| Fernández-Ayala, M | 1 |
| Nan, D | 1 |
| González-Macías, J | 1 |
| Kupila, L | 1 |
| Sonninen, V | 1 |
| Peltonen, R | 1 |
| Uksila, J | 1 |
| Hukkanen, V | 1 |
| Kotilainen, P | 1 |
| Chirgwin, K | 1 |
| Hafner, R | 2 |
| Remington, J | 1 |
| Andersen, J | 1 |
| Bosler, EM | 1 |
| Roque, C | 1 |
| Rajicic, N | 1 |
| McAuliffe, V | 1 |
| Jayaweera, DT | 1 |
| Luft, BJ | 4 |
| Iribarren, JA | 1 |
| Garde, C | 1 |
| Rodriguez-Arrondo, F | 1 |
| Blanco, A | 1 |
| Dannemann, B | 1 |
| McCutchan, JA | 2 |
| Israelski, D | 1 |
| Antoniskis, D | 2 |
| Luft, B | 1 |
| Nussbaum, J | 1 |
| Chiu, J | 2 |
| Molina, JM | 1 |
| Belenfant, X | 1 |
| Doco-Lecompte, T | 1 |
| Idatte, JM | 1 |
| Modai, J | 1 |
| Tenant-Flowers, M | 1 |
| Boyle, MJ | 1 |
| Carey, D | 1 |
| Marriott, DJ | 1 |
| Harkness, JL | 1 |
| Penny, R | 1 |
| Cooper, DA | 1 |
| Raguin, G | 1 |
| Fernandez-Martin, J | 1 |
| Niyongabo, T | 1 |
| Dannemann, BR | 1 |
| Israelski, DM | 1 |
| Nussbaum, JN | 1 |
| Orellana, M | 1 |
| Simon, DI | 1 |
| Brosius, FC | 1 |
| Rothstein, DM | 1 |
| Lindsay, DS | 1 |
| Carrazana, EJ | 1 |
| Rossitch, E | 1 |
| Samuels, MA | 1 |
| Cohn, JA | 1 |
| McMeeking, A | 1 |
| Cohen, W | 1 |
| Jacobs, J | 1 |
| Holzman, RS | 1 |
| Wanke, C | 1 |
| Tuazon, CU | 1 |
| Kovacs, A | 1 |
| Dina, T | 1 |
| Davis, DO | 1 |
| Barton, N | 1 |
| Katz, D | 1 |
| Lunde, M | 1 |
| Levy, C | 1 |
| Conley, FK | 1 |
| Lim, BT | 1 |
| Carbaat, PA | 1 |
| van Knapen, F | 1 |
| Meredith, JT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Dose-Escalation, Phase I/II Study of Oral Azithromycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDS[NCT00000966] | Phase 1 | 45 participants | Interventional | Completed | |||
| Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis[NCT00000794] | Phase 2 | 100 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for sulfadiazine and Brain Inflammation
| Article | Year |
|---|---|
Toxoplasma gondii: transmission, diagnosis and prevention.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antibodies, Protozoan; Cats; Cattle; Deer; Encephalitis | 2002 |
Issues in toxoplasmosis.
Topics: AIDS-Related Opportunistic Infections; Animals; Clindamycin; Drug Therapy, Combination; Encephalitis | 1993 |
Sulfadiazine-associated nephrotoxicity in patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Age | 1996 |
Sulfadiazine crystalluria revisited. The treatment of Toxoplasma encephalitis in patients with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adult; Crystallization; Drug Therapy, Combi | 1990 |
AIDS commentary. Toxoplasmic encephalitis.
Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-Bacterial Agents; Antibodies, Protozoan; Antimetab | 1988 |
12 trials available for sulfadiazine and Brain Inflammation
| Article | Year |
|---|---|
Synergistic sulfonamides plus clindamycin as an alternative therapeutic regimen for HIV-associated Toxoplasma encephalitis: a randomized controlled trial.
Topics: Acquired Immunodeficiency Syndrome; Azithromycin; Clindamycin; Encephalitis; Humans; Sulfadiazine; S | 2022 |
Twice-weekly maintenance therapy with sulfadiazine-pyrimethamine to prevent recurrent toxoplasmic encephalitis in patients with AIDS. Spanish Toxoplasmosis Study Group.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Drug Administration Schedule; Drug Therapy, Comb | 1995 |
Pyrimethamine plus azithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS.
Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Azithromycin; Drug Administration Sched | 1993 |
Pyrimethamine-clindamycin vs. pyrimethamine-sulfadiazine as acute and long-term therapy for toxoplasmic encephalitis in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Clindamycin; Drug Therapy, Comb | 1996 |
Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiprotozoal Agents; Atovaquone; Clindamycin; Encephalit | 1996 |
Randomized trial of trimethoprim-sulfamethoxazole versus pyrimethamine-sulfadiazine for therapy of toxoplasmic encephalitis in patients with AIDS. Italian Collaborative Study Group.
Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Anti-Infective Agents; Encephalitis; Female; | 1998 |
Thrice-weekly sulfadiazine-pyrimethamine for maintenance therapy of toxoplasmic encephalitis in HIV-infected patients. Spanish Toxoplasmosis Study Group.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Drug Therapy, Combination; Encep | 2000 |
TMP-SMX superior in treating Toxoplasma encephalitis.
Topics: Anti-Infective Agents; Encephalitis; Humans; Pyrimethamine; Randomized Controlled Trials as Topic; S | 1997 |
Randomized phase II trial of atovaquone with pyrimethamine or sulfadiazine for treatment of toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome: ACTG 237/ANRS 039 Study. AIDS Clinical Trials Group 237/Agence Nationale de Recherche
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; AIDS-Related Opportunistic Infections; Ani | 2002 |
Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Clindamycin; Drug Evaluation; Drug Therapy, Combination; | 1992 |
Evaluation of the efficacy and safety of clindamycin plus pyrimethamine for induction and maintenance therapy of toxoplasmic encephalitis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Drug Therapy, Combination; Encephalitis; Humans; Op | 1991 |
Treatment of acute toxoplasmosis with intravenous clindamycin. The California Collaborative Treatment Group.
Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Drug Therapy, Combination; Encephalitis; Humans; In | 1991 |
30 other studies available for sulfadiazine and Brain Inflammation
| Article | Year |
|---|---|
The Role of Sulfadiazine for the Treatment of Refractory Intracranial Infection.
Topics: Adult; Anti-Infective Agents; China; Encephalitis; Female; Humans; Male; Middle Aged; Retrospective | 2015 |
Treatment of Toxoplasma brain abscess with clindamycin and sulfadiazine in an AIDS patient with concurrent atypical Pneumocystis carinii pneumonia.
Topics: Adult; AIDS-Related Opportunistic Infections; Brain Abscess; Clindamycin; Drug Therapy, Combination; | 2002 |
Chemotherapy of toxoplasmic encephalitis in AIDS patients.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Encephalitis; Hum | 1989 |
[Renal failure caused by sulfadiazine in a HIV patient with toxoplasmic encephalitis].
Topics: Adult; Antiprotozoal Agents; Encephalitis; Female; HIV Infections; Humans; Sulfadiazine; Toxoplasmos | 2005 |
[Acute renal failure due to sulfadiazine crystalluria].
Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Alkalies; Animals; Antiprotozoal | 2007 |
Late cerebral relapse of congenital toxoplasmosis.
Topics: Child; Chorioretinitis; Drug Therapy, Combination; Encephalitis; Female; Humans; Pyrimethamine; Recu | 1980 |
Toxoplasmosis in AIDS: keeping the lid on.
Topics: AIDS-Related Opportunistic Infections; Drug Therapy, Combination; Encephalitis; Humans; Pyrimethamin | 1995 |
Acute renal failure due to sulphadiazine in a patient with acquired immunodeficiency syndrome (AIDS)
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infection | 1995 |
Toxoplasma gondii infection in advanced HIV infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Encephalitis; Female; Humans; Male; Middle Ag | 1994 |
Adverse cutaneous reactions to pyrimethamine/sulfadiazine and pyrimethamine/clindamycin in patients with AIDS and toxoplasmic encephalitis.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Clindamy | 1995 |
Nonionic block copolymers potentiate activities of drugs for treatment of infections with Toxoplasma gondii.
Topics: Animals; Anti-Infective Agents; Cytokines; Drug Synergism; Encephalitis; Female; Lymphocyte Activati | 1995 |
Folinic acid supplements to pyrimethamine-sulfadiazine for Toxoplasma encephalitis are associated with better outcome.
Topics: Antiprotozoal Agents; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Encephalitis; | 1996 |
Sulfadiazine-induced multiple urolithiasis and acute renal failure in a patient with AIDS and Toxoplasma encephalitis.
Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Crystalliz | 1996 |
Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; Brain; Clin | 1996 |
Toxoplasma encephalitis in a HIV patient: unusual involvement of the corpus callosum.
Topics: Adult; Animals; Anti-Infective Agents; Brain Neoplasms; Corpus Callosum; Diagnosis, Differential; En | 1997 |
Determination of the inhibitory effect on Toxoplasma growth in the serum of AIDS patients during acute therapy for toxoplasmic encephalitis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dr | 1998 |
Induction of tumor necrosis factor-alpha and inducible nitric oxide synthase fails to prevent toxoplasmic encephalitis in the absence of interferon-gamma in genetically resistant BALB/c mice.
Topics: Animals; Antigens, Protozoan; Antiprotozoal Agents; Brain; Disease Models, Animal; Encephalitis; Fem | 2000 |
[Kidney failure caused by sulphadiazine in patients with toxoplasma encephalitis].
Topics: Acute Kidney Injury; Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Encephaliti | 2000 |
[Toxoplasma encephalitis in a previously healthy man].
Topics: Abattoirs; Antiprotozoal Agents; Drug Therapy, Combination; Encephalitis; Humans; Male; Middle Aged; | 1999 |
Empiric treatment of acute Toxoplasma encephalitis in patients with acquired immunodeficiency syndrome.
Topics: AIDS-Related Opportunistic Infections; Encephalitis; Humans; Pyrimethamine; Sulfadiazine; Toxoplasmo | 1992 |
Sulfadiazine-induced crystalluria in AIDS patients with toxoplasma encephalitis.
Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adult; Crystallization; Encephalitis; Femal | 1991 |
Sulphadiazine desensitization in patients with AIDS and cerebral toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Brain Edema; Desensitization, Immun | 1991 |
Long-term follow-up of patients with AIDS on maintenance therapy for toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Drug Therapy, Combination; Encephalitis; Follow-Up | 1991 |
Effects of sulfadiazine and amprolium on Neospora caninum (Protozoa: Apicomplexa) infections in mice.
Topics: Acute Disease; Amprolium; Animals; Disease Models, Animal; Encephalitis; Female; Mice; Picolines; Pn | 1990 |
Toxoplasmic encephalitis.
Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Encephalitis; Humans; Opportunistic Infection | 1990 |
Cerebral toxoplasmosis in the acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Encephalitis; Female; Humans; Male; Middle Aged; Py | 1989 |
Evaluation of the policy of empiric treatment of suspected Toxoplasma encephalitis in patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopsy; Brain; Clindamycin; Encephalitis; Female; Humans; | 1989 |
Toxoplasma encephalitis in patients with acquired immune deficiency syndrome: diagnosis and response to therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antibodies; Drug Therapy, Combination; Encephalitis; Huma | 1987 |
[A young man with acute toxoplasmosis encephalitis].
Topics: Acute Disease; Adult; Drug Therapy, Combination; Encephalitis; Humans; Leucovorin; Male; Pyrimethami | 1987 |
Toxoplasmosis of the central nervous system.
Topics: Adult; Central Nervous System Diseases; Cerebellum; Encephalitis; Female; Humans; Pyrimethamine; Sul | 1987 |