sucrose and Hemophilia A

sucrose has been researched along with Hemophilia A in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's1 (2.94)18.2507
2000's17 (50.00)29.6817
2010's13 (38.24)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Chen, Z; Huang, K; Li, G; Wu, R; Wu, X; Zhen, Y1
Ay, Y; Cubukcu, D; Gozmen, S; Karapinar, TH; Oymak, Y; Toret, E; Vergin, RC1
Beckmann, H; Hou, Q; Hu, Y; Sun, J; Wu, J; Wu, R; Xiao, J; Yang, R; Zhao, Y1
Bonanad, S; Bosch, P; Cid, AR; Haya, S; Marqués, MR; Megías-Vericat, JE; Monte-Boquet, E; Pérez-Alenda, S; Poveda, JL; Querol, F1
Achilles, K; Rivard, GE; Rothschild, C; Toll, T1
Gercheva, L; Ghinea, M; Goranov, S; Hong, W; Kempton, CL; Lissitchkov, T; Manco-Johnson, MJ; Reding, MT; Rescia, V; Rusen, L; Uscatescu, V1
Chan, AK; Nagel, K; Steele, MR1
Delesen, H; Enriquez, MM; Lalezari, S; Martinowitz, U; Scharrer, I; Schwartz, L; Windyga, J1
Coppola, A; Enriquez, MM; Ingerslev, J; Lalezari, S; Lin, J; Powell, J; Tseneklidou-Stoeter, D1
Brunn, M; Meijer, K; Platokouki, H; Rauchensteiner, S; Santagostino, E; Schinco, PC; Schutgens, RE; Tueckmantel, C; Valeri, F1
Al Zoebie, A; Andreeva, T; Brunn, M; Gouider, E; Meddeb, B; Mehadzic, S; Nefyodova, L; Rauchensteiner, S; Tueckmantel, C1
Lalezari, S; Lubetsky, A; Luboshitz, J; Martinowitz, U; Spira, J1
Delumeau, JC; Haupt, V; Ikegawa, C; Yokoyama, C1
Andreeva, TA; Khametova, RN; Plyushch, OP; Spira, J1
Bajwa, N; Enriquez, MM; Gorina, E; Lemm, G1
Bashari, D; Gorina, E; Lubetsky, A; Luboshitz, J; Martinowitz, U; Ravid, B; Regan, L; Stass, H1
Achilles, K; Chen, RL; Hsueh, EJ; Huang, ML; Liu, HC; Maas-Enriquez, M; Peng, CT; Young, JH1
Collins, P; Enriquez, MM; Faradji, A; Morfini, M; Schwartz, L1
Konigs, C; von Hentig, N1
Aledort, LM1
Aledort, LM; Navickis, RJ; Wilkes, MM1
Di Minno, G; Hellmann, A; Ingerslev, J; Maas Enriquez, M; Martinowitz, U; Pabinger, I; Powell, J; Schwartz, L; Windyga, J1
FANTL, P1
Shi, J; Sun, J; Wang, L; Wu, J; Yang, R; Zhao, Y1
Carcao, M; Hensman, C; Lillicrap, D; Rivard, GE; Rubinger, M; Teitel, J; Walker, I1
Faradji, A; Gorina, E; Ingerslev, J; Iorio, A; Lambert, T; Maas-Enriquez, M; Musso, R; Santagostino, E; van der Meer, J1
Frampton, JE; Wagstaff, AJ1
Bainton, R; Laidlaw, S; Makris, M; Wilkie, M1
Abshire, TC; Brackmann, HH; Gazengel, C; Gorina, E; Hoots, K; Kellermann, E; Powell, JS; Scharrer, I; Vosburgh, E1
Fukutake, K; Shima, M; Shirahata, A; Takamatsu, J; Yoshioka, A2
Abshire, T; Brackmann, HH; Gazengel, C; Gorina, E; Kellermann, E; Ragni, M; Scharrer, I; Sultan, Y; Vosburgh, E1
Brackmann, HH; Effenberger, W; Rothschild, C; Scharrer, I; Stieltjes, N; Torchet, MF; Vicariot, M1
Scharrer, I1

Reviews

2 review(s) available for sucrose and Hemophilia A

ArticleYear
A review of current literature on second-generation, sucrose-formulated, full-length recombinant factor VIII.
    Drugs of today (Barcelona, Spain : 1998), 2009, Volume: 45, Issue:7

    Topics: Animals; Clinical Trials as Topic; Drug Evaluation, Preclinical; Excipients; Factor VIII; Hemophilia A; Hemorrhage; Humans; Sucrose

2009
Sucrose-formulated octocog alfa: a review of its use in patients with haemophilia A.
    Drugs, 2008, Volume: 68, Issue:6

    Topics: Blood Loss, Surgical; Chemistry, Pharmaceutical; Coagulants; Excipients; Factor VIII; Hemophilia A; Hemorrhage; Humans; Sucrose; Treatment Outcome

2008

Trials

15 trial(s) available for sucrose and Hemophilia A

ArticleYear
Efficacy of standard prophylaxis versus on-demand treatment with bayer's sucrose-formulated recombinant FVIII (rFVIII-FS) in Chinese children with severe hemophilia A.
    Pediatric hematology and oncology, 2017, Volume: 34, Issue:3

    Topics: Adolescent; Asian People; Child; Child, Preschool; China; Factor VIII; Female; Follow-Up Studies; Hemophilia A; Hemorrhage; Humans; Male; Sucrose; Time Factors

2017
Randomized, controlled, parallel-group trial of routine prophylaxis vs. on-demand treatment with sucrose-formulated recombinant factor VIII in adults with severe hemophilia A (SPINART).
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Drug Administration Schedule; Factor VIII; Hemophilia A; Hemorrhage; Humans; International Cooperation; Magnetic Resonance Imaging; Male; Middle Aged; Quality of Life; Sucrose; Treatment Outcome; Young Adult

2013
Correlation between endogenous VWF:Ag and PK parameters and bleeding frequency in severe haemophilia A subjects during three-times-weekly prophylaxis with rFVIII-FS.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2014, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Blood Coagulation Tests; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Factor VIII; Hemophilia A; Hemorrhage; Humans; Male; Middle Aged; Premedication; Severity of Illness Index; Sucrose; Treatment Outcome; von Willebrand Factor; Young Adult

2014
Patient characteristics that influence efficacy of prophylaxis with rFVIII-FS three times per week: a subgroup analysis of the LIPLONG study.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2014, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Double-Blind Method; Drug Administration Schedule; Factor VIII; Hemophilia A; Humans; Male; Middle Aged; Prospective Studies; Sucrose; Treatment Outcome; Young Adult

2014
Infusion rates of recombinant FVIII-FS with PEGylated liposomes in haemophilia A.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2008, Volume: 14, Issue:5

    Topics: Adult; Aged; Drug Administration Schedule; Factor VIII; Hemophilia A; Humans; Infusions, Intravenous; Liposomes; Male; Middle Aged; Polyethylene Glycols; Sucrose; Young Adult

2008
Evaluation of liposomal dose in recombinant factor VIII reconstituted with pegylated liposomes for the treatment of patients with severe haemophilia A.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:3

    Topics: Adult; Cross-Over Studies; Factor VIII; Hemophilia A; Hemorrhage; Humans; Liposomes; Male; Middle Aged; Models, Genetic; Polyethylene Glycols; Safety; Sucrose; Time Factors; Treatment Outcome

2008
Stability, efficacy, and safety of continuously infused sucrose-formulated recombinant factor VIII (rFVIII-FS) during surgery in patients with severe haemophilia.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2009, Volume: 15, Issue:3

    Topics: Adult; Blood Coagulation Factor Inhibitors; Factor VIII; Hemophilia A; Hemostasis; Hemostatics; Humans; Infusions, Intravenous; Male; Middle Aged; Postoperative Hemorrhage; Preoperative Care; Sucrose; Treatment Outcome

2009
Efficacy and safety of secondary prophylactic vs. on-demand sucrose-formulated recombinant factor VIII treatment in adults with severe hemophilia A: results from a 13-month crossover study.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:1

    Topics: Adult; Chemistry, Pharmaceutical; Coagulants; Cross-Over Studies; Drug Administration Schedule; Europe; Factor VIII; Hemarthrosis; Hemophilia A; Home Infusion Therapy; Humans; Infusions, Intravenous; Male; Middle Aged; Prospective Studies; Secondary Prevention; Severity of Illness Index; Sucrose; Time Factors; Treatment Outcome; United States

2010
Efficacy and safety of prophylaxis with once-weekly BAY 79-4980 compared with thrice-weekly rFVIII-FS in haemophilia A patients. A randomised, active-controlled, double-blind study.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:5

    Topics: Adolescent; Adult; Chemistry, Pharmaceutical; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Factor VIII; Hemophilia A; Hemorrhage; Humans; Liposomes; Male; Middle Aged; Polyethylene Glycols; Solvents; Sucrose; Treatment Outcome; Young Adult

2012
Safety and efficacy of sucrose-formulated full-length recombinant factor VIII: experience in the standard clinical setting.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:1

    Topics: Adolescent; Adult; Blood Coagulation Factor Inhibitors; Blood Loss, Surgical; Chemistry, Pharmaceutical; Child; Child, Preschool; Coagulants; Europe; Excipients; Factor VIII; Hemophilia A; Hemorrhage; Humans; Infant; Infusions, Parenteral; Male; Product Surveillance, Postmarketing; Prospective Studies; Recombinant Proteins; Severity of Illness Index; Sucrose; Time Factors; Treatment Outcome

2008
Sucrose formulated recombinant human antihemophilic factor VIII is safe and efficacious for treatment of hemophilia A in home therapy--International Kogenate-FS Study Group.
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Antibodies; Child; Cross-Over Studies; Drug Compounding; Drug Evaluation; Factor VIII; Hemophilia A; Hemorrhage; Home Infusion Therapy; Humans; Male; Middle Aged; Partial Thromboplastin Time; Patient Satisfaction; Recombinant Proteins; Sucrose; Time Factors; Treatment Outcome

2000
Pharmacokinetics, prophylactic effects, and safety of a new recombinant FVIII formulated with sucrose (BAY 14-2222) in Japanese patients with hemophilia A.
    International journal of hematology, 2000, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Child; Consumer Product Safety; Drug Evaluation; Factor VIII; Half-Life; Hemophilia A; Hemorrhage; Humans; Japan; Male; Middle Aged; Recombinant Proteins; Sucrose

2000
Efficacy of a sucrose-formulated recombinant factor VIII used for 22 surgical procedures in patients with severe haemophilia A.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2000, Volume: 6, Issue:6

    Topics: Acute Disease; Adult; Blood Loss, Surgical; Chemistry, Pharmaceutical; Factor VIII; Female; Hemophilia A; Humans; Male; Middle Aged; Recombinant Proteins; Sucrose; Treatment Outcome

2000
Safety and efficacy of a new recombinant FVIII formulated with sucrose (rFVIII-FS) in patients with haemophilia A: a long-term, multicentre clinical study in Japan.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2001, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Child; Cohort Studies; Consumer Product Safety; Drug Combinations; Factor VIII; Hemophilia A; Hemorrhage; Hemostasis; Humans; Isoantibodies; Japan; Longitudinal Studies; Middle Aged; Recombinant Proteins; Sucrose; Therapeutic Equivalency

2001
European data of a clinical trial with a sucrose formulated recombinant factor VIII in previously treated haemophilia A patients.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2002, Volume: 8 Suppl 2

    Topics: Adolescent; Adult; Blood Component Transfusion; Child; Consumer Product Safety; Factor VIII; Hemophilia A; Humans; Middle Aged; Sucrose; Treatment Outcome

2002

Other Studies

17 other study(ies) available for sucrose and Hemophilia A

ArticleYear
Comparative pharmacokinetics of Kogenate FS and Kovaltry in 14 Chinese paediatric patients with haemophilia A: A single-centre study.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2021, Volume: 27, Issue:2

    Topics: Child; China; Factor VIII; Hemophilia A; Humans; Sucrose

2021
Which tests can most effectively indicate the clinical phenotype of paediatric haemophilia patients with prophylaxis?
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2021, Jun-01, Volume: 32, Issue:4

    Topics: Adolescent; Blood Coagulation Tests; Child; Factor VIII; Hemophilia A; Hemorrhage; Humans; Sucrose; Thrombelastography; Thrombin

2021
Cross-sectional comparative study of pharmacokinetics and efficacy between sucrose-formulated recombinant factor VIII (Kogenate
    Haemophilia : the official journal of the World Federation of Hemophilia, 2019, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Child; Cross-Sectional Studies; Drug Compounding; Factor VIII; Female; Hemophilia A; Hemorrhage; Humans; Middle Aged; Sucrose; Treatment Outcome; Young Adult

2019
Immune tolerance induction in haemophilia A patients with inhibitors by treatment with recombinant factor VIII: a retrospective non-interventional study.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2013, Volume: 19, Issue:3

    Topics: Blood Coagulation Factor Inhibitors; Child; Child, Preschool; Factor VIII; Follow-Up Studies; Hemophilia A; Humans; Immune Tolerance; Infant; Male; Retrospective Studies; Sucrose; Time Factors

2013
Pharmacokinetics of recombinant and plasma-derived factor VIII products in paediatric patients with severe haemophilia A.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2014, Volume: 20, Issue:1

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Factor VIII; Hemophilia A; Humans; Infant; Infant, Newborn; Severity of Illness Index; Sucrose

2014
Continuous infusion of recombinant factor VIII formulated with sucrose in surgery: non-interventional, observational study in patients with severe haemophilia A.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2015, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Blood Loss, Surgical; Blood Transfusion; Factor VIII; Hemophilia A; Humans; Male; Middle Aged; Safety; Sucrose; Treatment Outcome; Young Adult

2015
Real-life evidence in evaluating effectiveness of treatment in Haemophilia A with a recombinant FVIII concentrate: a non-interventional study in emerging countries.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2015, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Coagulation Factor Inhibitors; Child; Child, Preschool; Factor VIII; Hemophilia A; Humans; Infant; Infections; Isoantibodies; Joint Diseases; Male; Middle Aged; Premedication; Sucrose; Treatment Outcome; Young Adult

2015
An observational study of sucrose-formulated recombinant factor VIII for Japanese patients with haemophilia A.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:1

    Topics: Adolescent; Adult; Antibodies; Chemistry, Pharmaceutical; Child; Child, Preschool; Coagulants; Consumer Product Safety; Excipients; Factor VIII; Female; Hemophilia A; Humans; Japan; Male; Product Surveillance, Postmarketing; Prospective Studies; Severity of Illness Index; Sucrose; Treatment Outcome

2008
Cumulative analysis of inhibitor formation in patients with haemophilia A treated with sucrose-formulated recombinant factor VIII.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2009, Volume: 15, Issue:2

    Topics: Factor VIII; Hemophilia A; Humans; Sucrose; Treatment Outcome

2009
Efficacy and safety evaluation of sucrose-formulated recombinant factor VIII for Taiwanese patients with haemophilia A.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2009, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Coagulants; Factor VIII; Hemophilia A; Humans; Male; Middle Aged; Product Surveillance, Postmarketing; Sucrose; Taiwan; Treatment Outcome; Young Adult

2009
To bleed or not to bleed - is that a question?
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:1

    Topics: Coagulants; Drug Administration Schedule; Factor VIII; Hemarthrosis; Hemophilia A; Home Infusion Therapy; Humans; Infusions, Intravenous; Secondary Prevention; Severity of Illness Index; Sucrose; Time Factors; Treatment Outcome

2010
Best evidence on B-domain deletion and the immunogenicity of recombinant factor VIII.
    Journal of thrombosis and haemostasis : JTH, 2011, Volume: 9, Issue:11

    Topics: Autoantibodies; Clinical Trials as Topic; Coagulants; Factor VIII; Hemarthrosis; Hemophilia A; Home Infusion Therapy; Humans; Immunogenetic Phenomena; Male; Secondary Prevention; Sucrose

2011
CLOTTING IN HEPARINISED PLASMA. II. UNDERLYING REACTIONS.
    The Australian journal of experimental biology and medical science, 1965, Volume: 43

    Topics: Anticoagulants; Antithrombin III; Blood Coagulation; Blood Coagulation Disorders; Blood Platelets; Calcium; Chemical Phenomena; Chemistry; Drug Therapy; Enzyme Inhibitors; Factor VII Deficiency; Glucose; Glycine; Hemophilia A; Heparin; Humans; Hypoprothrombinemias; Mannitol; Phospholipids; Sucrose; Thiourea; Thrombin; Thromboplastin

1965
Safety and efficacy of a sucrose-formulated recombinant factor VIII product for the treatment of previously treated patients with haemophilia A in China.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2007, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Child; China; Drug Evaluation; Factor VIII; Hemophilia A; Hemorrhage; Humans; Middle Aged; Risk Factors; Sucrose

2007
A prospective surveillance study of factor VIII inhibitor development in the Canadian haemophilia A population following the switch to a recombinant factor VIII product formulated with sucrose.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2008, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Autoantibodies; Canada; Child; Factor VIII; Follow-Up Studies; Hemophilia A; Hemostatics; Humans; Prospective Studies; Sucrose

2008
Acute renal failure in acquired haemophilia following the use of high dose intravenous immunoglobulin.
    Haemophilia : the official journal of the World Federation of Hemophilia, 1999, Volume: 5, Issue:4

    Topics: Acute Kidney Injury; Autoantibodies; Diabetes Mellitus; Factor VIII; Hemophilia A; Humans; Immunoglobulins, Intravenous; Male; Middle Aged; Sucrose

1999
Experience with KOGENATE Bayer in surgical procedures.
    Haemophilia : the official journal of the World Federation of Hemophilia, 2002, Volume: 8 Suppl 2

    Topics: Adult; Blood Loss, Surgical; Blood Transfusion; Child; Factor VIII; Hemophilia A; Hemostasis, Surgical; Humans; Middle Aged; Sucrose; Surgical Procedures, Operative

2002