Page last updated: 2024-11-04

succinylcholine and Poisoning

succinylcholine has been researched along with Poisoning in 17 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
" OP compounds act by irreversibly binding to pseudocholinesterase enzyme and hence prolong the apnea in patients being given suxamethonium."8.02Prolonged apnea after ECT in organophosphorus poisoning - the need to redefine norms. ( Dhillon, HS; Sasidharan, S, 2021)
" A 7-h period of apnea and paralysis after administration of succinylcholine was attributed to the decreased rate of succinylcholine metabolism resulting from inhibition of pseudocholinesterase by the insecticide."7.71Prolonged apnea following succinylcholine administration in undiagnosed acute organophosphate poisoning. ( Kocamanoglu, S; Sener, EB; Tur, A; Ustun, E, 2002)
" OP compounds act by irreversibly binding to pseudocholinesterase enzyme and hence prolong the apnea in patients being given suxamethonium."4.02Prolonged apnea after ECT in organophosphorus poisoning - the need to redefine norms. ( Dhillon, HS; Sasidharan, S, 2021)
" A 7-h period of apnea and paralysis after administration of succinylcholine was attributed to the decreased rate of succinylcholine metabolism resulting from inhibition of pseudocholinesterase by the insecticide."3.71Prolonged apnea following succinylcholine administration in undiagnosed acute organophosphate poisoning. ( Kocamanoglu, S; Sener, EB; Tur, A; Ustun, E, 2002)
"For the cases of sudden death or suspicious death, determination of suxamethonium chloride should be taken as a routine detection index to prevent missing inspection."1.46[Forensic Analysis for 54 Cases of Suxamethonium Chloride Poisoning]. ( Chen, FY; Ma, KJ; Zhang, J; Zhao, BQ; Zhao, YF, 2017)
" Detection of SUX as well as its metabolite succinylmonocholine (SMC) is difficult: both substances are analytically challenging, and the extremely short plasma half-life of SUX additionally hampers detection of the parent compound."1.37Pharmacokinetic properties of succinylmonocholine in surgical patients. ( Herbstreit, F; Hilger, RA; Kuepper, U; Madea, B; Musshoff, F, 2011)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's1 (5.88)18.2507
2000's4 (23.53)29.6817
2010's3 (17.65)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Sasidharan, S1
Dhillon, HS1
Zhao, YF1
Zhao, BQ1
Ma, KJ1
Zhang, J1
Chen, FY1
Kuepper, U2
Musshoff, F2
Madea, B2
Hilger, RA1
Herbstreit, F1
Sener, EB1
Ustun, E1
Kocamanoglu, S1
Tur, A1
PETERSON, DI1
HARDINGE, MG1
TILTON, BE1
DeBalli, P1
Cook, DR1
Yuan, HJ1
Yu, WY1
Shi, CH1
Sun, MJ1
Pellegrini, JE1
Baker, AB1
Fontenot, DJ1
Cardenas, AF1
Maeda, H1
Fujita, MQ1
Zhu, BL1
Ishidam, K1
Oritani, S1
Tsuchihashi, H1
Nishikawa, M1
Izumi, M1
Matsumoto, F1
Wattel, F1
Chopin, C1
Durocher, A1
Berzin, B1
Dronen, SC1
Merigian, KS1
Hedges, JR1
Hoekstra, JW1
Borron, SW1
Nelson, TC1
Burritt, MF1
Coulter, C1
Edmunds, J1
Pyle, PO1
Seybold, R2
Bräutigam, KH2
Ibe, K1

Reviews

1 review available for succinylcholine and Poisoning

ArticleYear
[Rhabdomyolysis in acute intoxications (author's transl)].
    La Nouvelle presse medicale, 1978, Sep-09, Volume: 7, Issue:29

    Topics: Alcoholic Intoxication; Anesthesia, General; Animals; Carbon Monoxide Poisoning; Foodborne Diseases;

1978

Trials

2 trials available for succinylcholine and Poisoning

ArticleYear
The effect of oral pyridostigmine bromide nerve agent prophylaxis on return of twitch height in persons receiving succinylcholine.
    Military medicine, 2000, Volume: 165, Issue:4

    Topics: Administration, Oral; Anesthesia, Inhalation; Chemical Warfare Agents; Cholinesterase Inhibitors; Do

2000
A comparison of blind nasotracheal and succinylcholine-assisted intubation in the poisoned patient.
    Annals of emergency medicine, 1987, Volume: 16, Issue:6

    Topics: Adult; Humans; Intubation, Intratracheal; Mouth; Nose; Pneumonia, Aspiration; Poisoning; Prospective

1987

Other Studies

14 other studies available for succinylcholine and Poisoning

ArticleYear
Prolonged apnea after ECT in organophosphorus poisoning - the need to redefine norms.
    BMC psychiatry, 2021, 03-10, Volume: 21, Issue:1

    Topics: Apnea; Electroconvulsive Therapy; Female; Humans; Neuromuscular Depolarizing Agents; Organophosphate

2021
[Forensic Analysis for 54 Cases of Suxamethonium Chloride Poisoning].
    Fa yi xue za zhi, 2017, Volume: 33, Issue:4

    Topics: Adult; Death, Sudden; Edema; Forensic Pathology; Forensic Toxicology; Humans; Lung; Male; Myocardium

2017
Applicability of succinylmonocholine as a marker for succinylcholine administration--comparative analysis of samples from a fatal succinylcholine-intoxication versus postmortem control specimens.
    Forensic science international, 2011, Apr-15, Volume: 207, Issue:1-3

    Topics: Biomarkers; Brain Chemistry; Case-Control Studies; Forensic Toxicology; Gas Chromatography-Mass Spec

2011
Pharmacokinetic properties of succinylmonocholine in surgical patients.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:5

    Topics: Adult; Aged; Blood Chemical Analysis; Female; Forensic Toxicology; Half-Life; Humans; Limit of Detec

2011
Prolonged apnea following succinylcholine administration in undiagnosed acute organophosphate poisoning.
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:8

    Topics: Acute Disease; Apnea; Diagnostic Errors; Dichlorvos; Food Contamination; Humans; Infant; Insecticide

2002
NEUROMUSCULAR BLOCK AS A POSSIBLE MECHANISM OF DEATH IN AMPHETAMINE POISONING.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 146

    Topics: Carbachol; Curare; Dextroamphetamine; Injections; Injections, Intraperitoneal; Neostigmine; Neuromus

1964
Treatment of sarin exposure.
    JAMA, 2004, Jan-14, Volume: 291, Issue:2

    Topics: Androstanols; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Humans; Intubation, Int

2004
Characteristics of recombinant human butyrylcholinesterase.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:1

    Topics: Animals; Butyrylcholinesterase; CHO Cells; Cricetinae; Electroporation; Mice; Plasmids; Poisoning; R

1999
A case of serial homicide by injection of succinylcholine.
    Medicine, science, and the law, 2000, Volume: 40, Issue:2

    Topics: Adult; Autopsy; Female; Gas Chromatography-Mass Spectrometry; Homicide; Humans; Male; Middle Aged; N

2000
Pesticide poisoning, succinylcholine-induced apnea, and pseudocholinesterase.
    Mayo Clinic proceedings, 1986, Volume: 61, Issue:9

    Topics: Apnea; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Dibucaine; Humans; Pestici

1986
An overdose of Parstelin.
    Anaesthesia, 1971, Volume: 26, Issue:4

    Topics: Adult; Diazepam; Humans; Male; Poisoning; Positive-Pressure Respiration; Spasm; Succinylcholine; Tac

1971
[Prolonged succinyl apnea as an indication of alkylphosphate poisoning].
    Deutsche medizinische Wochenschrift (1946), 1968, Jul-19, Volume: 93, Issue:29

    Topics: Adult; Anesthesia, General; Apnea; Cerebral Ventriculography; Cholinesterase Inhibitors; Humans; Ins

1968
Prolonged suxamethonium-induced apnoea as a sign of organophosphate poisoning.
    German medical monthly, 1969, Volume: 14, Issue:1

    Topics: Adult; Apnea; Humans; Male; Parathion; Phosphates; Poisoning; Succinylcholine; Suicide

1969
[Acute methaqualone poisoning. II. Clinical picture, pathophysiology and therapy].
    Archiv fur Toxikologie, 1966, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Blood Vessels; Female; Humans; Kidney; Liver; Male; Methaqualone; Middle Aged; Mu

1966