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succinylcholine and Obesity

succinylcholine has been researched along with Obesity in 19 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"We used published models to simulate the duration of unresponsiveness and ventilatory depression using a common induction technique with predicted rates of oxygen desaturation in various size patients and explored to what degree rapid reversal of rocuronium-induced neuromuscular blockade with sugammadex might improve the return of spontaneous ventilation in CICV situations."3.83The Myth of Rescue Reversal in "Can't Intubate, Can't Ventilate" Scenarios. ( Brewer, L; Johnson, KB; Kopman, AF; LaPierre, C; Naguib, M, 2016)
"In the elective obese or sleep apnea patient with no other risk factors for pulmonary aspiration, the risks and benefits of rapid sequence induction and cricoid pressure should be weighed."2.43The rapid sequence induction revisited: obesity and sleep apnea syndrome. ( Freid, EB, 2005)
"There are limited data regarding appropriateness of sedative and paralytic dosing of obese patients undergoing rapid sequence intubation (RSI) in the emergency department."1.43Accuracy of rapid sequence intubation medication dosing in obese patients intubated in the ED. ( Bhat, R; Dynin, M; Goyal, M; Mazer-Amirshahi, M; Sun, C; Tefera, E; Towle, D; Vaughns, J, 2016)
"The potency estimates for succinylcholine in obese (body mass index > 30 kg/m(2)) adolescents are comparable to those in similarly aged nonobese adolescents when dosing is calculated based on total body mass and not lean body mass."1.31The potency of succinylcholine in obese adolescents. ( Katz, MS; Rose, JB; Theroux, MC, 2000)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199011 (57.89)18.7374
1990's1 (5.26)18.2507
2000's4 (21.05)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Naguib, M1
Brewer, L1
LaPierre, C1
Kopman, AF1
Johnson, KB1
Bhat, R1
Mazer-Amirshahi, M1
Sun, C1
Vaughns, J1
Dynin, M1
Tefera, E1
Towle, D1
Goyal, M1
Cabaton, J1
Rondelet, B1
Gergele, L1
Besnard, C1
Piriou, V1
Minville, V1
Ruiz, S1
Ferre, F1
Gris, C1
Girbet, MN1
Freid, EB1
Van Lith, P1
Johnson, FN1
Sharp, JT1
Lee, C1
Katz, RL1
Kutty, KM1
Bentley, JB1
Borel, JD1
Vaughan, RW1
Gandolfi, AJ1
Dilger, JA1
Tetzlaff, JE1
Bell, GR1
Kosmorsky, GS1
Agnor, RC1
O'Hara, JF1
Rose, JB1
Theroux, MC1
Katz, MS1
Matthews, JM1
Fox, GS1
Dalrymple, DG1
Parbrook, GD1
Steel, DF1
Nelson, RA1
Miller, T1
Wulfsohn, NL1
Mignault, G1
Labrecque, B1
Hamel, S1
Warner, WA1
Garrett, LP1
Evers, W1
Racz, GB1
Dobkin, AB1

Reviews

2 reviews available for succinylcholine and Obesity

ArticleYear
The rapid sequence induction revisited: obesity and sleep apnea syndrome.
    Anesthesiology clinics of North America, 2005, Volume: 23, Issue:3

    Topics: Anesthesia, General; Humans; Neuromuscular Nondepolarizing Agents; Obesity; Pneumonia, Aspiration; S

2005
Biological function of cholinesterase.
    Clinical biochemistry, 1980, Volume: 13, Issue:6

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Butyrylcholinesterase; Choline; Cholinesterases; Clini

1980

Other Studies

17 other studies available for succinylcholine and Obesity

ArticleYear
The Myth of Rescue Reversal in "Can't Intubate, Can't Ventilate" Scenarios.
    Anesthesia and analgesia, 2016, Volume: 123, Issue:1

    Topics: Adult; Androstanols; Anesthesia Recovery Period; Anesthesia, General; Biomarkers; Body Mass Index; C

2016
Accuracy of rapid sequence intubation medication dosing in obese patients intubated in the ED.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:12

    Topics: Adult; Body Mass Index; Databases, Factual; Emergency Service, Hospital; Etomidate; Female; Humans;

2016
[Tako-Tsubo syndrome after anaphylaxis caused by succinylcholine during general anaesthesia].
    Annales francaises d'anesthesie et de reanimation, 2008, Volume: 27, Issue:10

    Topics: Anaphylaxis; Anesthesia, General; Anesthesia, Intravenous; Diabetes Mellitus, Type 2; Female; Gastro

2008
[Medication error: account the shape but the context too].
    Annales francaises d'anesthesie et de reanimation, 2012, Volume: 31, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Obstetrical; Anesthetics, Intravenous;

2012
Respiratory elastances in relaxed and paralyzed states in normal and abnormal men.
    Journal of applied physiology, 1967, Volume: 23, Issue:4

    Topics: Adult; Aged; Elasticity; Humans; Lung; Middle Aged; Muscle Contraction; Muscles; Neuromuscular Junct

1967
Neuromuscular pharmacology. A clinical update and commentary.
    British journal of anaesthesia, 1980, Volume: 52, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cholinesterase Inhibitors; Drug Interactions; Electric Stimulation;

1980
Weight, pseudocholinesterase activity, and succinylcholine requirement.
    Anesthesiology, 1982, Volume: 57, Issue:1

    Topics: Adult; Anesthesia, General; Body Surface Area; Body Weight; Butyrylcholinesterase; Cholinesterases;

1982
Ischaemic optic neuropathy after spinal fusion.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Loss, Surgi

1998
The potency of succinylcholine in obese adolescents.
    Anesthesia and analgesia, 2000, Volume: 90, Issue:3

    Topics: Adolescent; Child; Dose-Response Relationship, Drug; Humans; Neuromuscular Depolarizing Agents; Obes

2000
Succinylcholine-induced hyperkalemia and rhabdomyolysis in a patient with necrotizing pancreatitis.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:6

    Topics: Humans; Hyperkalemia; Male; Middle Aged; Neuromuscular Depolarizing Agents; Obesity; Pancreatitis, A

2000
Anaesthesia for intestinal short circuiting in the morbidly obese with reference to the pathophysiology of gross obesity.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, General; Epinephrine; Humans; Intestines; Intubation, Intratrachea

1975
Factors predisposing to postoperative pain and pulmonary complications: a study of female patients undergoing elective cholecystectomy.
    British journal of anaesthesia, 1973, Volume: 45, Issue:6

    Topics: Adolescent; Adult; Age Factors; Analgesics; Cholecystectomy; Female; Humans; Lung Diseases; Middle A

1973
Apneic anesthesia for microlaryngeal surgery.
    The Laryngoscope, 1973, Volume: 83, Issue:8

    Topics: Anesthesia, Intravenous; Apnea; Carbon Dioxide; Humans; Hydrogen-Ion Concentration; Laryngoscopy; La

1973
Succinylcholine dosage based on lean body mass.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Apnea; Body Weight; Female; Halothane; Humans; Intubat

1972
[Methoxyflurane and nephrotoxicity: study of the renal function in 22 patients anesthetized with methoxyflurane].
    Canadian Anaesthetists' Society journal, 1970, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Blood Urea Nitrogen; Creatinine; Diuresis; Female;

1970
The obese patient and anesthesia.
    JAMA, 1968, Jul-08, Volume: 205, Issue:2

    Topics: Adult; Anesthesia; Female; Humans; Meperidine; Mepivacaine; Methoxyflurane; Obesity; Pentobarbital;

1968
A study of plasma potassium and electrocardiographic changes after a single dose of succinylcholine.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:4

    Topics: Atropine; Bradycardia; Cardiovascular Diseases; Debridement; Diabetes Complications; Electrocardiogr

1969