succinylcholine has been researched along with Neuromuscular Blockade in 118 studies
Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.
Neuromuscular Blockade: The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study investigated the effect of preoperative consumption of potatoes on succinylcholine-induced block and recovery from anesthesia." | 9.17 | The effect of preoperative consumption of potatoes on succinylcholine-induced block and recovery from anesthesia. ( Bestas, A; Erhan, OL; Goksu, H, 2013) |
| "Muscle fasciculations were observed in 19 of the 20 patients in the control group and in 3 of the 20 patients in the rocuronium group, the best of the pretreatments in that aspect." | 9.08 | Rocuronium is the best non-depolarizing relaxant to prevent succinylcholine fasciculations and myalgia. ( Carrier, J; Claprood, Y; Martin, R; Pirlet, M; Tétrault, JP, 1998) |
| "In Auckland, the rate of anaphylaxis to succinylcholine and rocuronium is approximately 10-fold higher than to atracurium." | 7.81 | Anaphylaxis is more common with rocuronium and succinylcholine than with atracurium. ( Cooke, PJ; Fitzharris, P; Hannam, JA; Mitchell, SJ; Reddy, JI; van Schalkwyk, JM, 2015) |
| "Electromyographic (EMG) amplitudes were used to characterize muscle paralysis following administration of succinylcholine via the IV or IO route in four Yorkshire-cross swine." | 7.80 | Comparison of muscle paralysis after intravenous and intraosseous administration of succinylcholine in Swine. ( Burgert, J; Gegel, B; Johnson, D; Kilbourn, J; Loughren, MJ; Worth, K, 2014) |
| " Rarely, patients with butyrylcholinesterase deficiency may show marked sensitivity to succinylcholine, manifested clinically by severely prolonged neuromuscular paralysis and apnea." | 7.77 | Prolonged neuromuscular paralysis following rapid-sequence intubation with succinylcholine. ( Aiken, DC; Donnell, RW; Kaufman, SE; Magee, C, 2011) |
| "This study was conducted to compare recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex with succinylcholine during electroconvulsive therapy (ECT)." | 7.77 | Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy. ( Hoshi, H; Kadoi, Y; Nishida, A; Saito, S, 2011) |
| "Prolonged neuromuscular blockade from succinylcholine after neostigmine administration has been reported in patients with frank renal failure." | 7.70 | Marked prolongation of the succinylcholine effect two hours after neostigmine reversal of neuromuscular blockade in a patient with chronic renal insufficiency. ( Bailey, M; Burt, N; Joye, T; Williams, AR, 1999) |
| "Five hundred patients treated during the 5-year period met inclusion criteria, 180 (36%) of whom required an adjustment of the succinylcholine dosing either above (119 patients) or below (61 patients) the 0." | 5.48 | Extreme variability in succinylcholine dose for muscle relaxation in electroconvulsive therapy. ( Aloysi, AS; Bryson, EO; Kellner, CH; Li, EH; Majeske, M, 2018) |
| "Sugammadex allows rapid recovery from rocuronium-induced neuromuscular blockade." | 5.30 | Comparison of emergence agitation between succinylcholine and rocuronium-sugammadex in adults following closed reduction of a nasal bone fracture: a prospective randomized controlled trial. ( Cho, CK; Lee, SJ; Sung, TY, 2019) |
| "Rocuronium for cesarean delivery under general anesthesia is an alternative to succinylcholine for rapid-sequence induction of anesthesia because of the availability of sugammadex for reversal of neuromuscular blockade." | 5.22 | Low-Dose or High-Dose Rocuronium Reversed with Neostigmine or Sugammadex for Cesarean Delivery Anesthesia: A Randomized Controlled Noninferiority Trial of Time to Tracheal Intubation and Extubation. ( Adamus, M; Bartikova, I; Francakova, J; Harazim, H; Hejduk, K; Hlozkova, J; Hodicka, Z; Janku, P; Kirchnerova, M; Klucka, J; Kosinova, M; Krikava, I; Mrozek, Z; Obare Pyszkova, L; Pavlik, T; Prochazka, M; Robotkova, H; Seidlova, D; Sevcik, P; Stoudek, R; Stourac, P, 2016) |
| " The present study investigated the effect of preoperative consumption of potatoes on succinylcholine-induced block and recovery from anesthesia." | 5.17 | The effect of preoperative consumption of potatoes on succinylcholine-induced block and recovery from anesthesia. ( Bestas, A; Erhan, OL; Goksu, H, 2013) |
| "These results suggest that reversal of intense rocuronium or vecuronium neuromuscular blockade need not be delayed until return of appreciable neuromuscular function has been demonstrated." | 5.09 | Early and late reversal of rocuronium and vecuronium with neostigmine in adults and children. ( Bevan, DR; Bevan, JC; Collins, L; de Scheepers, LD; Fowler, C; Kahwaji, R; Rosen, HD; Smith, MF; Stephenson, CA, 1999) |
| "Muscle fasciculations were observed in 19 of the 20 patients in the control group and in 3 of the 20 patients in the rocuronium group, the best of the pretreatments in that aspect." | 5.08 | Rocuronium is the best non-depolarizing relaxant to prevent succinylcholine fasciculations and myalgia. ( Carrier, J; Claprood, Y; Martin, R; Pirlet, M; Tétrault, JP, 1998) |
| "We used published models to simulate the duration of unresponsiveness and ventilatory depression using a common induction technique with predicted rates of oxygen desaturation in various size patients and explored to what degree rapid reversal of rocuronium-induced neuromuscular blockade with sugammadex might improve the return of spontaneous ventilation in CICV situations." | 3.83 | The Myth of Rescue Reversal in "Can't Intubate, Can't Ventilate" Scenarios. ( Brewer, L; Johnson, KB; Kopman, AF; LaPierre, C; Naguib, M, 2016) |
| "In Auckland, the rate of anaphylaxis to succinylcholine and rocuronium is approximately 10-fold higher than to atracurium." | 3.81 | Anaphylaxis is more common with rocuronium and succinylcholine than with atracurium. ( Cooke, PJ; Fitzharris, P; Hannam, JA; Mitchell, SJ; Reddy, JI; van Schalkwyk, JM, 2015) |
| "Neuromuscular blockade duration in excess of 10 min occurred in 16% of a general surgical population following a single dose of succinylcholine." | 3.81 | Predictors of the variability in neuromuscular block duration following succinylcholine: A prospective, observational study. ( Burkhart, CS; Dell-Kuster, S; Girard, T; Hampl, K; Kindler, C; Lelais, F; Levano, S; Schobinger, E; Zemp, A, 2015) |
| "Electromyographic (EMG) amplitudes were used to characterize muscle paralysis following administration of succinylcholine via the IV or IO route in four Yorkshire-cross swine." | 3.80 | Comparison of muscle paralysis after intravenous and intraosseous administration of succinylcholine in Swine. ( Burgert, J; Gegel, B; Johnson, D; Kilbourn, J; Loughren, MJ; Worth, K, 2014) |
| "This study was conducted to compare recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex with succinylcholine during electroconvulsive therapy (ECT)." | 3.77 | Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy. ( Hoshi, H; Kadoi, Y; Nishida, A; Saito, S, 2011) |
| " Rarely, patients with butyrylcholinesterase deficiency may show marked sensitivity to succinylcholine, manifested clinically by severely prolonged neuromuscular paralysis and apnea." | 3.77 | Prolonged neuromuscular paralysis following rapid-sequence intubation with succinylcholine. ( Aiken, DC; Donnell, RW; Kaufman, SE; Magee, C, 2011) |
| "We compared the recovery time from neuromuscular blockade induced by rocuronium combined with sugammadex versus succinylcholine during electroconvulsive therapy (ECT)." | 3.77 | Use of rocuronium-sugammadex, an alternative to succinylcholine, as a muscle relaxant during electroconvulsive therapy. ( Hoshi, H; Kadoi, Y; Kamiyama, J; Nishida, A; Saito, H; Saito, S; Taguchi, M, 2011) |
| "This study investigates the effects of succinylcholine on the recovery of neuromuscular blockade produced by mivacurium in rats." | 3.74 | Effects of succinylcholine on the recovery of block produced by mivacurium in rats. ( Giala, M; Kanyamibwa, D; Karakoulas, K; Makedou, AH; Parlapani, A; Thomareis, O; Tsaousi, G, 2008) |
| "We report the case of a prolonged neuromuscular blockade in an 18-month-old age girl following administration of a usual dose of succinylcholine." | 3.73 | [Butyrylcholinesterase deficiency: how to analyse the cholinesterase activity in small children?]. ( Blanloeil, Y; Delaroche, O; Lejus, C; Pinaud, M; Trille, E, 2006) |
| " We describe a case of prolonged neuromuscular blockade following succinylcholine and mivacurium administration in a 24-year-old renal transplant patient undergoing repeated plasmapheresis for recurrence of focal segmental glomerulosclerosis and acute vascular rejection." | 3.71 | Prolonged neuromuscular block due to cholinesterase depletion by plasmapheresis. ( Dharnidharka, VR; Hirshhorn, S; Naik, B, 2002) |
| "Prolonged neuromuscular blockade from succinylcholine after neostigmine administration has been reported in patients with frank renal failure." | 3.70 | Marked prolongation of the succinylcholine effect two hours after neostigmine reversal of neuromuscular blockade in a patient with chronic renal insufficiency. ( Bailey, M; Burt, N; Joye, T; Williams, AR, 1999) |
| "Succinylcholine is a relaxant widely used but involves numerous complications." | 3.01 | Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery. ( Aragón-Benedí, C; Fernández-Liesa, R; Martínez-Ubieto, J; Ortega-Lucea, S; Pascual-Bellosta, A; Visiedo-Sánchez, S, 2021) |
| "Rocuronium has rapid onset at higher doses, but with a prolonged duration of action." | 2.84 | Optimal anesthetic regimen for ambulatory laser microlaryngeal surgery. ( Baek, SK; Cho, JE; Huh, H; Jung, KY; Lee, HW; Lim, HH; Lim, HJ; Park, SJ; Yoon, SZ, 2017) |
| "Rocuronium at 0." | 2.76 | A randomized trial to identify optimal precurarizing dose of rocuronium to avoid precurarization-induced neuromuscular block. ( Fukano, N; Ishikawa, K; Mizutani, H; Ogawa, S; Saeki, S; Suzuki, T, 2011) |
| "Adult patients with head injuries were prospectively enrolled over a 1-year period by using the following inclusion criteria: Glasgow Coma Scale score of 3 to 8, transport time of greater than 10 minutes, and inability to intubate without RSI." | 2.70 | Paramedic-performed rapid sequence intubation of patients with severe head injuries. ( Bailey, D; Davis, D; Hoyt, D; Marshall, L; Ochs, M; Rosen, P, 2002) |
| "Rapacuronium (RAP) is a new, rapid-onset, short-duration, nondepolarizing neuromuscular blocker." | 2.70 | Duration of action of vecuronium after an intubating dose of rapacuronium, vecuronium, or succinylcholine. ( Alexander, R; El-Moalem, H; Gan, TJ; Glass, PS; Jhaveri, R; Madan, R; Weatherwax, K, 2001) |
| "Rocuronium has an onset of action more rapid than other non-depolarizing neuromuscular blocking agents, but it is unclear whether it and succinylcholine give equivalent intubating conditions during rapid-sequence induction of anaesthesia." | 2.69 | A large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol. ( Andrews, JI; Kumar, N; Olkkola, KT; Roest, GJ; van den Brom, RH; Wright, PM, 1999) |
| "Mivacurium was unsatisfactory in eight cases compared with two cases after succinylcholine." | 2.69 | Low dose mivacurium is less effective than succinylcholine in electroconvulsive therapy. ( Cheam, EW; Chui, PT; Critchley, LA; Ha, VW; Yap, JC, 1999) |
| " There were no neonatal adverse effects in either group based on: Apgar scores at 1 and 5 min; times to sustained respiration; neuroadaptive capacity scores at 15 min, 2 h and 24 h; and umbilical venous and arterial blood-gas values and acid-base status." | 2.69 | Rapacuronium for modified rapid sequence induction in elective caesarean section: neuromuscular blocking effects and safety compared with succinylcholine, and placental transfer. ( Abboud, TK; Abboud, TS; Abouleish, EI; Bikhazi, G; Kenaan, CA; Lee, J; Mroz, L; Zhu, J, 1999) |
| " The present dose-response data support the use of rocuronium at a dose of 1." | 2.68 | Dose-response of rocuronium bromide in children anesthetized with propofol: a comparison with succinylcholine. ( Choo, SM; Crawford, MW; Woolf, RL, 1997) |
| " However, because maturational changes in certain of these characteristics counterbalance, dosing requirements do not differ markedly with age." | 2.40 | Neuromuscular blocking agents in paediatric anaesthesia. ( Fisher, DM, 1999) |
| "Five hundred patients treated during the 5-year period met inclusion criteria, 180 (36%) of whom required an adjustment of the succinylcholine dosing either above (119 patients) or below (61 patients) the 0." | 1.48 | Extreme variability in succinylcholine dose for muscle relaxation in electroconvulsive therapy. ( Aloysi, AS; Bryson, EO; Kellner, CH; Li, EH; Majeske, M, 2018) |
| "Succinylcholine has numerous side effects." | 1.35 | [Muscle relaxants in the ICU]. ( Schneider, G, 2009) |
| "Morphine was used most commonly (66%), with other opioids and benzodiazepines used less frequently." | 1.31 | Premedication before intubation in UK neonatal units. ( Birrell, G; Whyte, S; Wyllie, J, 2000) |
| "Tacrine is a cholinesterase inhibitor used to manage Alzheimer's dementia." | 1.30 | Tacrine does not alter the potency of succinylcholine in the rat. ( Donati, F; Eshelby, D; Fox, GS; Ibebunjo, C; Tchervenkov, JI, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (9.32) | 18.7374 |
| 1990's | 37 (31.36) | 18.2507 |
| 2000's | 29 (24.58) | 29.6817 |
| 2010's | 34 (28.81) | 24.3611 |
| 2020's | 7 (5.93) | 2.80 |
| Authors | Studies |
|---|---|
| Bash, LD | 1 |
| Black, W | 1 |
| Turzhitsky, V | 1 |
| Urman, RD | 1 |
| Thomsen, JLD | 1 |
| Mathiesen, O | 1 |
| Hägi-Pedersen, D | 1 |
| Skovgaard, LT | 1 |
| Østergaard, D | 1 |
| Gätke, MR | 2 |
| Gonzalez-Estrada, A | 1 |
| Carrillo-Martin, I | 1 |
| Morgenstern-Kaplan, D | 1 |
| Garzon-Siatoya, WT | 1 |
| Renew, JR | 1 |
| Hernandez-Torres, V | 1 |
| Volcheck, GW | 2 |
| Wong, P | 1 |
| Ashby, O | 1 |
| Lee, SJ | 1 |
| Sung, TY | 1 |
| Cho, CK | 1 |
| Aragón-Benedí, C | 1 |
| Visiedo-Sánchez, S | 1 |
| Pascual-Bellosta, A | 1 |
| Ortega-Lucea, S | 1 |
| Fernández-Liesa, R | 1 |
| Martínez-Ubieto, J | 1 |
| Patel, S | 1 |
| Mintjens, N | 1 |
| Brummans, R | 1 |
| Soetens, F | 1 |
| Claes, KBM | 1 |
| Vanlinthout, LE | 1 |
| Sauer, M | 1 |
| Piel, I | 1 |
| Haubner, C | 1 |
| Richter, G | 1 |
| Mann, M | 1 |
| Nöldge-Schomburg, G | 2 |
| Mencke, T | 1 |
| Bryson, EO | 1 |
| Kellner, CH | 1 |
| Li, EH | 1 |
| Aloysi, AS | 1 |
| Majeske, M | 1 |
| Andersson, ML | 1 |
| Møller, AM | 1 |
| Wildgaard, K | 1 |
| Gerlach, RM | 1 |
| Shahul, S | 1 |
| Wroblewski, KE | 1 |
| Cotter, EKH | 1 |
| Perkins, BW | 1 |
| Harrison, JH | 1 |
| Ota, T | 1 |
| Jeevanandam, V | 1 |
| Chaney, MA | 1 |
| Bestas, A | 1 |
| Goksu, H | 1 |
| Erhan, OL | 1 |
| Li, YL | 1 |
| Liu, YL | 1 |
| Xu, CM | 1 |
| Lv, XH | 1 |
| Wan, ZH | 1 |
| Brandom, BW | 2 |
| Veyckemans, F | 1 |
| Jurkolow, G | 1 |
| Fuchs-Buder, T | 3 |
| Lemoine, A | 1 |
| Raft, J | 1 |
| Rocq, N | 1 |
| Meistelman, C | 1 |
| Cassel, J | 1 |
| Staehr-Rye, AK | 1 |
| Nielsen, CV | 1 |
| Loughren, MJ | 1 |
| Kilbourn, J | 1 |
| Worth, K | 1 |
| Burgert, J | 1 |
| Gegel, B | 1 |
| Johnson, D | 1 |
| Baraka, A | 2 |
| Mertes, PM | 1 |
| Reddy, JI | 1 |
| Cooke, PJ | 1 |
| van Schalkwyk, JM | 1 |
| Hannam, JA | 1 |
| Fitzharris, P | 1 |
| Mitchell, SJ | 1 |
| Schmartz, D | 1 |
| Girard, T | 3 |
| Schreiber, JU | 2 |
| Schuller, PJ | 1 |
| Newell, S | 1 |
| Strickland, PA | 1 |
| Barry, JJ | 1 |
| Dell-Kuster, S | 1 |
| Levano, S | 2 |
| Burkhart, CS | 1 |
| Lelais, F | 1 |
| Zemp, A | 1 |
| Schobinger, E | 1 |
| Hampl, K | 1 |
| Kindler, C | 1 |
| Dewachter, P | 1 |
| Mouton-Faivre, C | 1 |
| Batistaki, C | 1 |
| Tentes, P | 1 |
| Deligiannidi, P | 1 |
| Karakosta, A | 1 |
| Florou, P | 1 |
| Kostopanagiotou, G | 1 |
| Stourac, P | 1 |
| Adamus, M | 1 |
| Seidlova, D | 1 |
| Pavlik, T | 1 |
| Janku, P | 1 |
| Krikava, I | 1 |
| Mrozek, Z | 1 |
| Prochazka, M | 1 |
| Klucka, J | 1 |
| Stoudek, R | 1 |
| Bartikova, I | 1 |
| Kosinova, M | 1 |
| Harazim, H | 1 |
| Robotkova, H | 1 |
| Hejduk, K | 1 |
| Hodicka, Z | 1 |
| Kirchnerova, M | 1 |
| Francakova, J | 1 |
| Obare Pyszkova, L | 1 |
| Hlozkova, J | 1 |
| Sevcik, P | 1 |
| Naguib, M | 4 |
| Brewer, L | 1 |
| LaPierre, C | 1 |
| Kopman, AF | 3 |
| Johnson, KB | 1 |
| Asakura, C | 1 |
| Iwasaki, H | 1 |
| Huh, H | 1 |
| Park, SJ | 1 |
| Lim, HH | 1 |
| Jung, KY | 1 |
| Baek, SK | 1 |
| Yoon, SZ | 1 |
| Lee, HW | 1 |
| Lim, HJ | 1 |
| Cho, JE | 1 |
| Kanyamibwa, D | 1 |
| Tsaousi, G | 1 |
| Karakoulas, K | 1 |
| Thomareis, O | 1 |
| Parlapani, A | 1 |
| Makedou, AH | 1 |
| Giala, M | 1 |
| Lee, C | 4 |
| Katz, RL | 2 |
| Jahr, JS | 1 |
| Candiotti, KA | 1 |
| Warriner, B | 1 |
| Zornow, MH | 1 |
| Schneider, G | 1 |
| Suzuki, T | 2 |
| Aono, M | 1 |
| Isaka, T | 1 |
| Miyake, E | 1 |
| Fukano, N | 2 |
| Saeki, S | 2 |
| Ogawa, S | 2 |
| Umesh, G | 1 |
| Jasvinder, K | 1 |
| Shetty, N | 1 |
| Gallart, L | 1 |
| Bermejo, S | 1 |
| Santiveri, X | 1 |
| Escolano, F | 1 |
| Puig, MM | 1 |
| Taha, SK | 1 |
| El-Khatib, MF | 1 |
| Baraka, AS | 1 |
| Haidar, YA | 1 |
| Abdallah, FW | 1 |
| Zbeidy, RA | 1 |
| Siddik-Sayyid, SM | 1 |
| Ishikawa, K | 1 |
| Mizutani, H | 1 |
| Hoshi, H | 2 |
| Kadoi, Y | 2 |
| Kamiyama, J | 1 |
| Nishida, A | 2 |
| Saito, H | 1 |
| Taguchi, M | 1 |
| Saito, S | 2 |
| Kaufman, SE | 1 |
| Donnell, RW | 1 |
| Aiken, DC | 1 |
| Magee, C | 1 |
| Watts, RW | 1 |
| London, JA | 1 |
| van Wijk, RM | 1 |
| Lui, YL | 1 |
| Beny, K | 1 |
| Mirabaud, AF | 1 |
| Piriou, V | 1 |
| Aulagner, G | 1 |
| Armoiry, X | 1 |
| McHugh, SM | 1 |
| Ibinson, JW | 1 |
| Ochs, M | 2 |
| Davis, D | 1 |
| Hoyt, D | 1 |
| Bailey, D | 2 |
| Marshall, L | 1 |
| Rosen, P | 2 |
| Naik, B | 1 |
| Hirshhorn, S | 1 |
| Dharnidharka, VR | 1 |
| van Santen, G | 1 |
| Wierda, JM | 2 |
| Fidler, V | 1 |
| Messner, M | 1 |
| Beese, U | 1 |
| Romstöck, J | 1 |
| Dinkel, M | 1 |
| Tschaikowsky, K | 1 |
| LAMMERS, W | 1 |
| THESLEFT, S | 1 |
| KOHN, R | 2 |
| BOVET, D | 1 |
| STOVNER, J | 1 |
| WISLICKI, L | 1 |
| BENZAKEIN, F | 1 |
| DEBLASI, S | 1 |
| KATSURASHIMA, T | 1 |
| BONO, F | 1 |
| LANZETTA, A | 1 |
| MAGGI, U | 1 |
| MAPELLI, A | 1 |
| BOVET-NITTI, F | 1 |
| MAROTTA, M | 1 |
| PINTOSCOGNAMIGLIO, W | 1 |
| SILVESTRINI, B | 1 |
| PETERSON, DI | 1 |
| HARDINGE, MG | 1 |
| TILTON, BE | 1 |
| Davis, DP | 1 |
| Hoyt, DB | 1 |
| Marshall, LK | 1 |
| LOW, H | 1 |
| TAMMELIN, LE | 1 |
| Ginz, H | 1 |
| Siegemund, M | 1 |
| Filipovic, M | 1 |
| Voronkov, E | 1 |
| Urwyler, A | 1 |
| Ramirez, JG | 1 |
| Sprung, J | 1 |
| Keegan, MT | 1 |
| Hall, BA | 1 |
| Bourke, DL | 1 |
| Lemmens, HJ | 1 |
| Brodsky, JB | 1 |
| Lejus, C | 2 |
| Delaroche, O | 1 |
| Trille, E | 1 |
| Blanloeil, Y | 2 |
| Pinaud, M | 1 |
| Mastakar, S | 1 |
| Leschinskiry, D | 1 |
| Abdulatif, M | 1 |
| al-Ghamdi, A | 1 |
| el-Sanabary, M | 1 |
| Symington, MJ | 1 |
| McCoy, EP | 1 |
| Mirakhur, RK | 4 |
| Kumar, N | 2 |
| Osmer, C | 1 |
| Vogele, C | 1 |
| Zickmann, B | 1 |
| Hempelmann, G | 1 |
| Theroux, MC | 1 |
| Zagnoev, MM | 1 |
| Drago, L | 1 |
| Uchida, K | 1 |
| Aoki, T | 1 |
| Satoh, H | 1 |
| Tajiri, O | 1 |
| Booij, LH | 2 |
| Parr, MJ | 1 |
| Manara, AR | 1 |
| Ibebunjo, C | 1 |
| Eshelby, D | 1 |
| Donati, F | 1 |
| Fox, GS | 1 |
| Tchervenkov, JI | 1 |
| Berkahn, JM | 1 |
| Sleigh, JW | 1 |
| Samarkandi, AH | 1 |
| Ammar, A | 1 |
| Turkistani, A | 1 |
| Kim, SY | 1 |
| Lee, JS | 1 |
| Kim, SC | 1 |
| Park, W | 1 |
| Woolf, RL | 1 |
| Crawford, MW | 1 |
| Choo, SM | 1 |
| Leuwer, M | 1 |
| Zuzan, O | 1 |
| Haeseler, G | 1 |
| Sparr, HJ | 3 |
| Stoddart, PA | 1 |
| Mather, SJ | 1 |
| Ma, OJ | 1 |
| Atchley, RB | 1 |
| Hatley, T | 1 |
| Green, M | 1 |
| Young, J | 1 |
| Brady, W | 1 |
| Martin, R | 1 |
| Carrier, J | 1 |
| Pirlet, M | 1 |
| Claprood, Y | 1 |
| Tétrault, JP | 1 |
| MacIntyre, PA | 1 |
| Ansari, KA | 1 |
| Muir, AW | 1 |
| Sleigh, T | 1 |
| Marshall, RJ | 1 |
| Pow, E | 1 |
| Anderson, KA | 1 |
| Hill, DR | 1 |
| Burnat, P | 1 |
| Souron, R | 1 |
| McCourt, KC | 1 |
| Salmela, L | 1 |
| Carroll, M | 1 |
| Mäkinen, MT | 1 |
| Kansanaho, M | 1 |
| Kerr, C | 1 |
| Roest, GJ | 2 |
| Olkkola, KT | 3 |
| Green, DW | 1 |
| Fisher, M | 1 |
| Sockalingham, I | 1 |
| Engbaek, J | 2 |
| Viby-Mogensen, J | 1 |
| Andrews, JI | 1 |
| van den Brom, RH | 1 |
| Wright, PM | 2 |
| Williams, AR | 1 |
| Bailey, M | 1 |
| Joye, T | 1 |
| Burt, N | 1 |
| Klewicka, MM | 1 |
| Kopman, DJ | 1 |
| Neuman, GG | 1 |
| Cheam, EW | 1 |
| Critchley, LA | 1 |
| Chui, PT | 1 |
| Yap, JC | 1 |
| Ha, VW | 1 |
| Fuentes de Frutos, AL | 1 |
| Muriel Villoria, C | 1 |
| Romo Cortina, MT | 1 |
| Bevan, JC | 1 |
| Collins, L | 1 |
| Fowler, C | 1 |
| Kahwaji, R | 1 |
| Rosen, HD | 1 |
| Smith, MF | 1 |
| de Scheepers, LD | 1 |
| Stephenson, CA | 1 |
| Bevan, DR | 1 |
| Manullang, J | 1 |
| Egan, TD | 1 |
| Mellinghoff, H | 1 |
| Blobner, M | 2 |
| Le Corre, F | 1 |
| Plaud, B | 1 |
| Benhamou, E | 1 |
| Debaene, B | 2 |
| de Rossi, L | 1 |
| Preussler, NP | 1 |
| Pühringer, FK | 1 |
| Klein, U | 1 |
| Fisher, DM | 1 |
| Whyte, S | 1 |
| Birrell, G | 1 |
| Wyllie, J | 1 |
| Abouleish, EI | 1 |
| Abboud, TK | 1 |
| Bikhazi, G | 1 |
| Kenaan, CA | 1 |
| Mroz, L | 1 |
| Zhu, J | 1 |
| Lee, J | 1 |
| Abboud, TS | 1 |
| Hayes, A | 1 |
| Breslin, D | 1 |
| Reid, J | 1 |
| Hemmerling, TM | 1 |
| Schmidt, J | 1 |
| Wolf, T | 1 |
| Klein, P | 1 |
| Jacobi, K | 1 |
| Cara, DM | 1 |
| Armory, P | 1 |
| Mahajan, RP | 2 |
| Pendeville, P | 1 |
| Rietbergen, H | 1 |
| Girling, KJ | 1 |
| Spendlove, JL | 1 |
| Quraishi, MS | 1 |
| Gan, TJ | 1 |
| Madan, R | 1 |
| Alexander, R | 1 |
| Jhaveri, R | 1 |
| El-Moalem, H | 1 |
| Weatherwax, K | 1 |
| Glass, PS | 1 |
| Wisely, NA | 1 |
| Mayall, R | 1 |
| Cerf, C | 1 |
| Mesguish, M | 1 |
| Gabriel, I | 1 |
| Amselem, S | 1 |
| Duvaldestin, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improving Neuromuscular Monitoring and Reducing Residual Neuromuscular Blockade Via E-learning - a Multicenter Interrupted Time Series Study (INVERT Study)[NCT02925143] | 6,525 participants (Actual) | Interventional | 2016-11-21 | Completed | |||
| Deep Versus Moderate Neuromuscular Blockade for Optimising Surgical Conditions Include Patient Benefits During Spinal Surgery: A Randomized Controlled Double Blinded Clinical Study[NCT02778945] | Phase 4 | 60 participants (Anticipated) | Interventional | 2016-09-01 | Recruiting | ||
| Impact of Anxiety on the Decision-making Process of Anesthesiologists in the Choice of Drugs for Induction of General Anesthesia of Patients With Aspiration Risk Factors[NCT05364801] | 500 participants (Anticipated) | Observational | 2022-05-02 | Recruiting | |||
| Ultrasound Assessment of Gastric Content and Gastric Volume Before Crash Induction for Appendectomy[NCT02983175] | 150 participants (Anticipated) | Interventional | 2016-12-31 | Not yet recruiting | |||
| Bispectral Index: A Comparison of Bifrontal Montage Agreement[NCT04062240] | 15 participants (Actual) | Observational | 2019-11-27 | Completed | |||
| The Effect of Prophylactic Magnesium Use in Pregnant Women on Reversal of Neuromuscular Block With Sugammadex:Evaluation With TOF[NCT05558969] | 30 participants (Anticipated) | Interventional | 2022-09-28 | Recruiting | |||
| A Multicenter, Randomized, Parallel Group, Comparative, Active-Controlled, Safety-Assessor Blinded, Phase IIIa, Trial, in Adult Subjects Comparing Recovery From 1.2 mg.Kg-1 Rocuronium Followed by 16 mg.Kg-1 Org 25969 at 3 Minutes With Recovery From 1.0 mg[NCT00474253] | Phase 3 | 115 participants (Actual) | Interventional | 2006-02-10 | Completed | ||
| Comparison of the Effectiveness of Rocuronium - Sugammadex With Succinylcholine-Cisatracurium-Neostigmine in Patients Undergoing Laser Microlaryngeal Surgery[NCT02329964] | Phase 4 | 80 participants (Actual) | Interventional | 2015-02-28 | Active, not recruiting | ||
| A Double-Blind, Randomized, Crossover Design Study To Compare The Rocuronium Reversal By Sugammadex To Succinylcholine For Electroconvulsive Therapy (ECT)[NCT03532178] | Phase 2 | 44 participants (Actual) | Interventional | 2019-01-01 | Completed | ||
| Effects of Neuromuscular Block Reversal With Sugammadex vs Neostigmine on Postoperative Respiratory Outcomes After Major Abdominal Surgery - A Randomized Controlled Trial[NCT02361060] | Phase 4 | 130 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| "A Less-rapid Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the Duration of Apnea Without Desaturation in Paralyzed Non-obese and Morbidly Obese Patients?"[NCT02943629] | 0 participants (Actual) | Interventional | 2016-11-30 | Withdrawn (stopped due to Lack of feasibility) | |||
| EEG-based Depth of Anesthesia-monitoring During General Anesthesia - Effects on Time to Wake-up and Post-operative Cognition[NCT04529304] | 100 participants (Anticipated) | Interventional | 2021-01-08 | Recruiting | |||
| Study of Intubation Time Required for Excellent Tracheal Intubation With Low Dose Rocuronium During Propofol Anaesthesia in Children With and Without Atropine[NCT01464489] | 44 participants (Actual) | Interventional | 2011-05-31 | Completed | |||
| The Effect of Precurarization With Rocuronium on the Incidence and Severity of Succinylcholine-Induced Fasciculations and Myalgias in a High Volume ERCP Center[NCT04581395] | Phase 3 | 300 participants (Actual) | Interventional | 2020-10-02 | Completed | ||
| Optimal Control of Muscle Strength for Electroconvulsive Therapy: A Comparison of Succinylcholine Versus Rocuronium-induced Neuromuscular Blockade[NCT01441960] | 45 participants (Actual) | Interventional | 2011-05-31 | Completed | |||
| Comparison of Two Induction Regimens Using Topical Lidocaine or Muscle Relaxant; Impact on Postoperative Sore Throat and Haemodynamics[NCT03031808] | Phase 4 | 100 participants (Anticipated) | Interventional | 2017-10-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"If the total dose of neostigmine is bigger than (>) the first dose administered, the outcome is yes." (NCT02925143)
Timeframe: in the period from induction of anaesthesia to discharge from the post-anaesthesia care unit, usually 5 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| E-learning Course | 213 |
"If the total dose of neostigmine in the anaesthesia information management system is > 0, the outcome is yes." (NCT02925143)
Timeframe: in the period from induction of anaesthesia to discharge from the post-anaesthesia care unit, usually 5 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| E-learning Course | 2047 |
"If the total dose of sugammadex in the anaesthesia information management system is > 0, the outcome is yes." (NCT02925143)
Timeframe: in the period from induction of anaesthesia to discharge from the post-anaesthesia care unit, usually 5 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| E-learning Course | 85 |
Number of Participants Who Received a Depolarizing Neuromuscular Blocking Agent (NMBA) (Succinylcholine) and was Monitored with Objective Neuromuscular Monitoring (Acceleromyography). Data on neuromuscular monitoring is automatically registered in the electronic patient chart when the equipment for acceleromyography is activated. (NCT02925143)
Timeframe: in the period from induction of anaesthesia to termination of anaesthesia, usually 2 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| E-learning Course | 1425 |
Number of Participants Who Received a Non-depolarizing Neuromuscular Blocking Agent (NMBA) and was Monitored with Objective Neuromuscular Monitoring (Acceleromyography). Data on neuromuscular monitoring is automatically registered in the electronic patient chart when the equipment for acceleromyography is activated. (NCT02925143)
Timeframe: in the period from induction of anaesthesia to termination of anaesthesia, usually 2 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| E-learning Course | 3172 |
The Train-of-four (TOF) ratio is the ratio of the fourth to the first muscle response after 4 stimuli at the ulnar nerve at the wrist at 2 Hz. The response is measured using acceleromyography. If the last measurement is performed before return of any muscle function, the ration can not be given. (NCT02925143)
Timeframe: in the period from induction of anaesthesia to termination of anaesthesia, usually 2 hours]
| Intervention | ratio (Mean) |
|---|---|
| E-learning Course | 95.23 |
(NCT02925143)
Timeframe: in the period from induction of anaesthesia to discharge from the post-anaesthesia care unit, usually 180 minutes
| Intervention | minutes (Median) |
|---|---|
| E-learning Course | 100 |
"Degree of variability between the values produced by the BIS sensors in a bifrontal montage when monitored simultaneously by use of a Bland-Altmann plot. The average value of each timed pair was plotted against the difference between the pairs.~The BIS monitor outputs data on a scale of 0-100 in arbitrary units; 0 = an isoelectric state on EEG, 100 = fully awake patient. BIS values of 40-60 are thought to reduce the chance of patient recall during general anesthesia.~For the purpose of this study, a smaller confidence interval is better as it indicates a higher level of agreement between the two BIS sensors." (NCT04062240)
Timeframe: 10 minutes where both sensors are recording concurrently
| Intervention | units on a scale (Mean) |
|---|---|
| Additional BIS Sensor | 0.01 |
Neuromuscular functioning was monitored by applying repetitive Train-Of-Four (TOF) electrical stimulations to the ulnar nerve every 15 seconds and assessing twitch response at the adductor pollicis muscle. T1 refers to the amplitude (height) of the first twitch after TOF nerve stimulation. (NCT00474253)
Timeframe: Up to 15 minutes after administration of rocuronium + sugammadex or succinylcholine
| Intervention | Minutes (Mean) |
|---|---|
| Rocuronium + Sugammadex | 4.35 |
| Succinylcholine | 7.15 |
Neuromuscular functioning was monitored by applying repetitive TOF electrical stimulations to the ulnar nerve every 15 seconds and assessing twitch response at the adductor pollicis muscle. T1 refers to the amplitude (height) of the first twitch after TOF nerve stimulation. (NCT00474253)
Timeframe: Up to 20 minutes after administration of rocuronium + sugammadex or succinylcholine
| Intervention | Minutes (Mean) |
|---|---|
| Rocuronium + Sugammadex | 6.13 |
| Succinylcholine | 11.03 |
The number of participants aroused with minimal stimulation was assessed as part of an overall assessment of level of consciousness. The level of consciousness was used as a measure of recovery from neuromuscular blockade at two time points: prior to transfer to the recovery room after extubation and prior to discharge from the recovery room. Attempts were made to arouse participants every 15 minutes with mild prodding, mild shaking, and asking questions regarding name, location, and day of the week. The assessment ended once the participant was awake and fully orientated. (NCT00474253)
Timeframe: Up to 24 hours after administration of rocuronium + sugammadex or succinylcholine
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Prior to transfer to recovery room | Prior to discharge from recovery room | |
| Rocuronium + Sugammadex | 7 | 1 |
| Succinylcholine | 15 | 2 |
The number of participants who were awake and oriented was assessed as part of an overall assessment of the clinical level of consciousness. The clinical level of consciousness was used as a measure of recovery from neuromuscular blockade at two time points: prior to transfer to the recovery room after extubation and prior to discharge from the recovery room. Attempts were made to arouse participants every 15 minutes with mild prodding, mild shaking, and asking questions regarding name, location, and day of the week. The assessment ended once the participant was awake and fully orientated. (NCT00474253)
Timeframe: Up to 24 hours after administration of rocuronium + sugammadex or succinylcholine
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Prior to transfer to recovery room | Prior to discharge from recovery room | |
| Rocuronium + Sugammadex | 8 | 19 |
| Succinylcholine | 13 | 33 |
The number of participants responsive only to tactile stimulation was assessed as part of an overall assessment of the level of consciousness. The level of consciousness was used as a measure of recovery from neuromuscular blockade at two time points: prior to transfer to the recovery room after extubation and prior to discharge from the recovery room. Attempts were made to arouse participants every 15 minutes with mild prodding, mild shaking, and asking questions regarding name, location, and day of the week. The assessment ended once the participant was awake and fully orientated. (NCT00474253)
Timeframe: Up to 24 hours after administration of rocuronium + sugammadex or succinylcholine
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Prior to transfer to recovery room | Prior to discharge from recovery room | |
| Rocuronium + Sugammadex | 5 | 0 |
| Succinylcholine | 7 | 0 |
The number of participants who were able to lift their head for 5 seconds was assessed as a measure of recovery following neuromuscular blockade at two time points: prior to transfer to the recovery room after extubation and prior to discharge from the recovery room. The assessment was performed every 15 minutes until the first successful 5-second head lift was achieved. (NCT00474253)
Timeframe: Up to 24 hours after administration of rocuronium + sugammadex or succinylcholine
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Prior to transfer to recovery room | Prior to discharge from recovery room | |
| Rocuronium + Sugammadex | 13 | 20 |
| Succinylcholine | 24 | 35 |
The number of participants experiencing general muscle weakness was assessed by the investigator as a measure of recovery from neuromuscular blockade at two time points: prior to transfer to the recovery room after extubation and prior to discharge from the recovery room. The assessments were performed every 15 minutes until the absence of general muscle weakness. A standardized examination form was used to determine the presence or absence of muscle weakness in various muscle groups. (NCT00474253)
Timeframe: Up to 24 hours after administration of rocuronium + sugammadex or succinylcholine
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Prior to transfer to recovery room | Prior to discharge from recovery room | |
| Rocuronium + Sugammadex | 2 | 0 |
| Succinylcholine | 3 | 0 |
"Repeated small boluses or drip of Succinylcholine, or small boluses of nondepolarizing muscle relaxants with intermediate duration are usually followed.~In this protocol, cisatracurium was injected after intubation to maintain neuromuscular blockade during surgery.~We measure the requirement of additive dose of neuromuscular blocker to ensure that neuromuscular blockade remains below T2 during surgery" (NCT02329964)
Timeframe: during surgery
| Intervention | participants (Number) |
|---|---|
| R-S Group | 0 |
| S-C-N Group | 20 |
time from propofol injection to extubation (NCT02329964)
Timeframe: from the anesthesia start to end
| Intervention | minutes (Mean) |
|---|---|
| R-S Group | 28.4 |
| S-C-N Group | 35.2 |
LMS surgery has short operation time and ambulatory setting. So the length of stay in the operating room will have significant. We expected the lengh of stay in the operating room is more shorter in R-S group than S-C-N group. (NCT02329964)
Timeframe: time from in to out of the operating room
| Intervention | minutes (Mean) |
|---|---|
| R-S Group | 31.0 |
| S-C-N Group | 38.6 |
we measure the time from the end of surgery to recovery of the TOF 0.1. The end of surgery is defined as the time when the direct laryngoscope, aided by an operation microscope, is removed. (NCT02329964)
Timeframe: from the end of surgery to time when the TOF ratio is 0.1, up to 30 minutes
| Intervention | seconds (Median) |
|---|---|
| R-S Group | 271 |
| S-C-N Group | 190 |
we measure the time from the end of surgery to recovery of the TOF 0.9. The end of surgery is defined as the time when the direct laryngoscope, aided by an operation microscope, is removed. (NCT02329964)
Timeframe: from the end of surgery(when the surgeon removes the suspension laryngoscope ) to time when the TOF ratio is 0.9, up to 30 minutes
| Intervention | seconds (Median) |
|---|---|
| R-S Group | 377 |
| S-C-N Group | 240 |
"describe by surgeon under his subjective opinion.~1 - extremely poor conditions 2- poor conditions 3- acceptable conditions 4- good conditions 5- optimal conditions" (NCT02329964)
Timeframe: during surgery
| Intervention | score (Median) |
|---|---|
| R-S Group | 5.0 |
| S-C-N Group | 5.0 |
We expected the emergence time is shorter in R-S group than S-C-N group. So we measure the time from the end of surgery to recovery of the TOF 0.9, and the time from the end of surgery to extubation (NCT02329964)
Timeframe: from the end of surgery to extubate a tracheal tube
| Intervention | seconds (Median) |
|---|---|
| R-S Group | 430 |
| S-C-N Group | 380 |
We expected the emergence time is shorter in R-S group than S-C-N group. So we measure the time from the end of surgery to opening of the eyes to verbal commands. (NCT02329964)
Timeframe: from end of surgery to opening of the eyes to verbal commands
| Intervention | seconds (Median) |
|---|---|
| R-S Group | 340 |
| S-C-N Group | 300 |
time from end of surgery to first spontaneous breaths (NCT02329964)
Timeframe: from end of surgery to first spontaneous breaths
| Intervention | seconds (Median) |
|---|---|
| R-S Group | 263 |
| S-C-N Group | 240 |
The time of neuromuscular recovery from sugammadex 4mg/kg dose reversal rocuronium at 0.6 mg/kg compared with traditionally used succinylcholine in electroconvulsive therapy (ECT). (NCT03532178)
Timeframe: 30 minutes
| Intervention | minutes (Mean) |
|---|---|
| Muscle Relaxant #1 | 6.79 |
| Muscle Relaxant #2 | 10.97 |
To document the side-effect profiles of sugammadex reversal of rocuronium and succhinylcholine in the ECT patient population (NCT03532178)
Timeframe: 24 hours after the procedure
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Nausea | Myalgia | Headache | |
| Rocuronium + Sugammadex | 1 | 1 | 7 |
| Succinylcholine + Normal Saline | 3 | 2 | 9 |
The investigators defined the compound specific differences in time to recovery from neuromuscular blockade - i.e., recovery of spontaneous breathing and recovery of the twitch height to baseline. (NCT01441960)
Timeframe: Up to six weeks following inclusion
| Intervention | minutes (Mean) |
|---|---|
| Succinylchline | 9.7 |
| Rocuronium | 19.5 |
Observational reports suggest that differences in seizure duration might exist depending on the neuromuscular blocking agents used to accomplish muscle strength control during ECT. (NCT01441960)
Timeframe: Up to six weeks following inclusion
| Intervention | Seconds (Mean) |
|---|---|
| Succinylcholine | 27 |
| Rocuronium | 31 |
The optimal dose of muscle neuromuscular blocking is defined as the lowest dose of either compound that predicts 'acceptable' control of muscle strength during ECT. Assessment of the primary end point is based on a dichotomous scale 'acceptable' and 'not acceptable' control of muscle strength during ECT, and the two assessors will be blinded to the dose of neuromuscular blocking agent. The optimal dose was identified for each subject, and results were reported as the average of all lowest doses collected in the study. (NCT01441960)
Timeframe: Up to six weeks following inclusion
| Intervention | mg.kg-1 (Mean) |
|---|---|
| NMBA: Sux | 0.85 |
| NMBA- Rocuronium | 0.41 |
8 reviews available for succinylcholine and Neuromuscular Blockade
| Article | Year |
|---|---|
Erroneous neuraxial administration of neuromuscular blocking drugs: Clinical and human factors analysis.
Topics: Humans; Neuromuscular Blockade; Pharmaceutical Preparations; Rocuronium; Succinylcholine; Vecuronium | 2020 |
Butyrylcholinesterase deficiency and its clinical importance in anaesthesia: a systematic review.
Topics: Anesthesia; Apnea; Butyrylcholinesterase; Humans; Metabolism, Inborn Errors; Mivacurium; Neuromuscul | 2019 |
Goodbye suxamethonium!
Topics: Anesthesia Recovery Period; Humans; Neuromuscular Blockade; Neuromuscular Depolarizing Agents; Neuro | 2009 |
Clinical implications of new neuromuscular concepts and agents: so long, neostigmine! So long, sux!
Topics: Androstanols; Anesthesia Recovery Period; Chemistry, Pharmaceutical; Cholinesterase Inhibitors; Dose | 2009 |
[Neuromuscular blockades. Agents, monitoring and antagonism].
Topics: Anesthesia; Humans; Monitoring, Intraoperative; Muscle Relaxation; Neuromuscular Blockade; Neuromusc | 2006 |
Neuromuscular transmission and its pharmacological blockade. Part 3: Continuous infusion of relaxants and reversal and monitoring of relaxation.
Topics: Electromyography; Humans; Infusions, Parenteral; Monitoring, Physiologic; Muscle Relaxants, Central; | 1997 |
[Cholinesterases].
Topics: Acetylcholinesterase; Anesthetics, Local; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholines | 1998 |
Neuromuscular blocking agents in paediatric anaesthesia.
Topics: Adult; Child; Humans; Neuromuscular Blockade; Neuromuscular Blocking Agents; Neuromuscular Depolariz | 1999 |
37 trials available for succinylcholine and Neuromuscular Blockade
| Article | Year |
|---|---|
Comparison of emergence agitation between succinylcholine and rocuronium-sugammadex in adults following closed reduction of a nasal bone fracture: a prospective randomized controlled trial.
Topics: Adult; Anesthesia, General; Closed Fracture Reduction; Double-Blind Method; Emergence Delirium; Fema | 2019 |
Study of Rocuronium-Sugammadex as an Alternative to Succinylcholine-Cisatracurium in Microlaryngeal Surgery.
Topics: Aged; Atracurium; Drug Combinations; Female; Humans; Laryngeal Diseases; Larynx; Male; Middle Aged; | 2021 |
Intraoperative Use of Nondepolarizing Neuromuscular Blocking Agents During Cardiac Surgery and Postoperative Pulmonary Complications: A Prospective Randomized Trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atracurium; Cardiac Surgical Procedures; Female; Follow- | 2019 |
The effect of preoperative consumption of potatoes on succinylcholine-induced block and recovery from anesthesia.
Topics: Adjuvants, Anesthesia; Adult; Alkaloids; Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhala | 2013 |
The effects of neuromuscular blockade on operating conditions during general anesthesia for spinal surgery.
Topics: Adult; Airway Extubation; Airway Resistance; Anesthesia Recovery Period; Anesthesia, General; Atracu | 2014 |
Low-Dose or High-Dose Rocuronium Reversed with Neostigmine or Sugammadex for Cesarean Delivery Anesthesia: A Randomized Controlled Noninferiority Trial of Time to Tracheal Intubation and Extubation.
Topics: Adolescent; Adult; Androstanols; Anesthesia, General; Anesthesia, Obstetrical; Antidotes; Cesarean S | 2016 |
Optimal anesthetic regimen for ambulatory laser microlaryngeal surgery.
Topics: Ambulatory Surgical Procedures; Androstanols; Atracurium; Cholinesterase Inhibitors; Double-Blind Me | 2017 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Reversal of profound neuromuscular block by sugammadex administered three minutes after rocuronium: a comparison with spontaneous recovery from succinylcholine.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Drug Interactions; Female; Follow | 2009 |
Effect of landiolol hydrochloride on suxamethonium-induced neuromuscular block.
Topics: Adrenergic beta-Antagonists; Adult; Anesthesia Recovery Period; Electric Stimulation; Female; Gyneco | 2009 |
Effect of suxamethonium vs rocuronium on onset of oxygen desaturation during apnoea following rapid sequence induction.
Topics: Adult; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Fasci | 2010 |
A randomized trial to identify optimal precurarizing dose of rocuronium to avoid precurarization-induced neuromuscular block.
Topics: Adult; Androstanols; Female; Humans; Middle Aged; Neuromuscular Blockade; Neuromuscular Junction; Ne | 2011 |
Paramedic-performed rapid sequence intubation of patients with severe head injuries.
Topics: Adult; Allied Health Personnel; Craniocerebral Trauma; Emergency Medical Services; Humans; Hypnotics | 2002 |
The dose of succinylcholine in morbid obesity.
Topics: Adult; Anesthesia, General; Body Mass Index; Body Weight; Double-Blind Method; Female; Gastric Bypas | 2006 |
Rocuronium priming of atracurium-induced neuromuscular blockade: the use of short priming intervals.
Topics: Adult; Androstanols; Anesthesia, General; Atracurium; Drug Combinations; Elective Surgical Procedure | 1996 |
Duration of stabilization of control responses affects the onset and duration of action of rocuronium but not suxamethonium.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia Recovery Period; Female; Humans; Male; Middle Aged | 1996 |
Combinations of high-dose vecuronium and mivacurium provide similar paralysis and intubation conditions to succinylcholine in paediatric patients.
Topics: Child; Double-Blind Method; Electromyography; Humans; Intubation, Intratracheal; Isoquinolines; Miva | 1996 |
Comparison of suxamethonium and different combinations of rocuronium and mivacurium for rapid tracheal intubation in children.
Topics: Androstanols; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Synergism; Female; Hum | 1997 |
Dose-response of rocuronium bromide in children anesthetized with propofol: a comparison with succinylcholine.
Topics: Androstanols; Anesthetics, Intravenous; Child; Child, Preschool; Dose-Response Relationship, Drug; E | 1997 |
Onset of neuromuscular blockade and intubating conditions one minute after the administration of rocuronium in children.
Topics: Androstanols; Anesthetics, Intravenous; Child; Double-Blind Method; Female; Humans; Intubation, Intr | 1998 |
Rocuronium is the best non-depolarizing relaxant to prevent succinylcholine fasciculations and myalgia.
Topics: Adult; Androstanols; Atracurium; Double-Blind Method; Fasciculation; Female; Follow-Up Studies; Huma | 1998 |
Comparison of rocuronium and suxamethonium for use during rapid sequence induction of anaesthesia.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia, Intravenous; Dose-Response Relationship, Drug; Do | 1998 |
Mivacurium compared with succinylcholine in children with liver disease.
Topics: Child; Child, Preschool; Cholinesterases; Endoscopy, Digestive System; Humans; Intubation, Intratrac | 1998 |
A large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol.
Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Cough; Ele | 1999 |
Molar potency is predictive of the speed of onset of neuromuscular block for agents of intermediate, short, and ultrashort duration.
Topics: Adult; Androstanols; Atracurium; Female; Humans; Male; Middle Aged; Neuromuscular Blockade; Neuromus | 1999 |
Low dose mivacurium is less effective than succinylcholine in electroconvulsive therapy.
Topics: Adult; Aged; Anesthesia Recovery Period; Cross-Over Studies; Double-Blind Method; Electroconvulsive | 1999 |
[Conditions of intubation and neuromuscular block induced by mivacurium: comparison with succinylcholine].
Topics: Adolescent; Adult; Aged; Female; Histamine Release; Humans; Intubation, Intratracheal; Isoquinolines | 1999 |
Early and late reversal of rocuronium and vecuronium with neostigmine in adults and children.
Topics: Adult; Androstanols; Child; Child, Preschool; Cholinesterase Inhibitors; Female; Humans; Male; Neost | 1999 |
Comparison of intubating conditions after rapacuronium (Org 9487) and succinylcholine following rapid sequence induction in adult patients.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Blood Pressure; Double-Blind Method; Female; Heart Rat | 1999 |
Visual estimation of onset time at the orbicularis oculi after five muscle relaxants: application to clinical monitoring of tracheal intubation.
Topics: Adolescent; Adult; Aged; Androstanols; Atracurium; Electric Stimulation; Eyelids; Facial Muscles; Fa | 1999 |
Onset of neuromuscular block at the masseter and adductor pollicis muscles following rocuronium or succinylcholine.
Topics: Adolescent; Adult; Androstanols; Anesthesia, General; Female; Humans; Masseter Muscle; Middle Aged; | 1999 |
Rapacuronium for modified rapid sequence induction in elective caesarean section: neuromuscular blocking effects and safety compared with succinylcholine, and placental transfer.
Topics: Adolescent; Adult; Anesthesia, Obstetrical; Cesarean Section; Female; Humans; Infant, Newborn; Mater | 1999 |
Comparison of recovery following rapacuronium, with and without neostigmine, and succinylcholine.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, General; Cholinesterase Inhibitors; Femal | 2000 |
Comparison of succinylcholine with two doses of rocuronium using a new method of monitoring neuromuscular block at the laryngeal muscles by surface laryngeal electromyography.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Androstanols; Electromyography; Female; Humans | 2000 |
Prolonged duration of neuromuscular block with rapacuronium in the presence of sevoflurane.
Topics: Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; Drug Interactions; Humans; Me | 2000 |
Rapacuronium 2.0 or 2.5 mg kg-1 for rapid-sequence induction: comparison with succinylcholine 1.0 mg kg-1.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Blood Pressure; Dose-Response Relat | 2000 |
Video imaging to assess neuromuscular blockade at the larynx.
Topics: Adult; Bronchoscopes; Electric Stimulation; Female; Fiber Optic Technology; Humans; Larynx; Male; Mo | 2001 |
Duration of action of vecuronium after an intubating dose of rapacuronium, vecuronium, or succinylcholine.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Electromyography; Female; Humans; Intubation, Intratra | 2001 |
73 other studies available for succinylcholine and Neuromuscular Blockade
| Article | Year |
|---|---|
Neuromuscular Blockade and Reversal Practice Variability in the Outpatient Setting: Insights From US Utilization Patterns.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Anesthesia | 2021 |
Improving neuromuscular monitoring and reducing residual neuromuscular blockade via e-learning: A multicentre interrupted time-series study (INVERT study).
Topics: Computer-Assisted Instruction; Delayed Emergence from Anesthesia; Humans; Interrupted Time Series An | 2022 |
The Nonirritating Concentrations of Neuromuscular Blocking Agents and Related Compounds.
Topics: Adult; Androstanols; gamma-Cyclodextrins; Humans; Neostigmine; Neuromuscular Blockade; Neuromuscular | 2023 |
Monitoring and Antagonism of Neuromuscular Blockade: Problems with Succinylcholine.
Topics: Anesthetics; Neuromuscular Blockade; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Succ | 2023 |
Timing of blood sampling for butyrylcholinesterase phenotyping in patients with prolonged neuromuscular block after mivacurium or suxamethonium.
Topics: Apnea; Butyrylcholinesterase; Humans; Mivacurium; Neuromuscular Blockade; Succinylcholine | 2021 |
Rocuronium is more hepatotoxic than succinylcholine in vitro.
Topics: Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Liver; Neuromu | 2017 |
Extreme variability in succinylcholine dose for muscle relaxation in electroconvulsive therapy.
Topics: Adult; Electroconvulsive Therapy; Humans; Mental Disorders; Muscle Relaxation; Neuromuscular Blockad | 2018 |
Neuromuscular diseases in children: a practical approach.
Topics: Adolescent; Anesthesia; Child; Child, Preschool; Humans; Hypertension, Malignant; Infant; Infant, Ne | 2013 |
[Prolonged phase II neuromuscular blockade following succinylcholine administration].
Topics: Adult; Butyrylcholinesterase; Humans; Male; Monitoring, Physiologic; Mutation; Neuromuscular Blockad | 2014 |
Use of neuromuscular monitoring to detect prolonged effect of succinylcholine or mivacurium: three case reports.
Topics: Accelerometry; Aged; Antidotes; Apnea; Appendicitis; Butyrylcholinesterase; Cholecystectomy, Laparos | 2014 |
Comparison of muscle paralysis after intravenous and intraosseous administration of succinylcholine in Swine.
Topics: Administration, Intravenous; Animals; Cross-Over Studies; Electromyography; Infusions, Intraosseous; | 2014 |
Succinylcholine neuromuscular block in the myasthenia gravis patient.
Topics: Humans; Myasthenia Gravis; Neuromuscular Blockade; Neuromuscular Depolarizing Agents; Succinylcholin | 2014 |
Anaphylaxis to neuromuscular-blocking drugs: all neuromuscular-blocking drugs are not the same.
Topics: Anaphylaxis; Androstanols; Atracurium; Female; Humans; Male; Neuromuscular Blockade; Neuromuscular N | 2015 |
Anaphylaxis is more common with rocuronium and succinylcholine than with atracurium.
Topics: Adult; Aged; Aged, 80 and over; Anaphylaxis; Androstanols; Atracurium; Causality; Cohort Studies; Fe | 2015 |
Anaphylaxis is more common with rocuronium and succinylcholine than with atracurium.
Topics: Adult; Aged; Aged, 80 and over; Anaphylaxis; Androstanols; Atracurium; Causality; Cohort Studies; Fe | 2015 |
Anaphylaxis is more common with rocuronium and succinylcholine than with atracurium.
Topics: Adult; Aged; Aged, 80 and over; Anaphylaxis; Androstanols; Atracurium; Causality; Cohort Studies; Fe | 2015 |
Anaphylaxis is more common with rocuronium and succinylcholine than with atracurium.
Topics: Adult; Aged; Aged, 80 and over; Anaphylaxis; Androstanols; Atracurium; Causality; Cohort Studies; Fe | 2015 |
The never ending story or the search for a nondepolarising alternative to succinylcholine.
Topics: Androstanols; Anesthesia, General; Anesthesia, Obstetrical; Female; Humans; Male; Neuromuscular Bloc | 2013 |
Pro: rocuronium should replace succinylcholine for rapid sequence induction.
Topics: Androstanols; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Female; Humans; Intuba | 2013 |
Con: succinylcholine should not be replaced by rocuronium for rapid sequence induction.
Topics: Androstanols; Anesthesia, General; Humans; Intubation, Intratracheal; Neuromuscular Blockade; Neurom | 2013 |
Response of bispectral index to neuromuscular block in awake volunteers.
Topics: Adult; Androstanols; Cognition; Electroencephalography; Electromyography; Female; Humans; Male; Midd | 2015 |
Predictors of the variability in neuromuscular block duration following succinylcholine: A prospective, observational study.
Topics: Adult; Aged; Butyrylcholinesterase; Female; Humans; Male; Middle Aged; Mutation; Neuromuscular Block | 2015 |
Anaphylaxis incidence with rocuronium, succinylcholine, and atracurium: how risk communication can influence behavior.
Topics: Anaphylaxis; Androstanols; Atracurium; Female; Humans; Male; Neuromuscular Blockade; Neuromuscular N | 2015 |
Residual neuromuscular blockade in a real life clinical setting: correlation with sugammadex or neostigmine administration.
Topics: Androstanols; Anesthesia Recovery Period; Atracurium; Delayed Emergence from Anesthesia; Female; gam | 2016 |
The Myth of Rescue Reversal in "Can't Intubate, Can't Ventilate" Scenarios.
Topics: Adult; Androstanols; Anesthesia Recovery Period; Anesthesia, General; Biomarkers; Body Mass Index; C | 2016 |
The use of succinylcholine after sugammadex reversal.
Topics: Androstanols; gamma-Cyclodextrins; Neuromuscular Blockade; Neuromuscular Nondepolarizing Agents; Suc | 2016 |
Effects of succinylcholine on the recovery of block produced by mivacurium in rats.
Topics: Animals; Cholinesterases; Drug Interactions; Isoquinolines; Male; Mivacurium; Neuromuscular Blockade | 2008 |
Have we learned how to relax our patients, by thinking outside the box?
Topics: Anesthesiology; Cholinesterase Inhibitors; Critical Care; gamma-Cyclodextrins; Humans; Neuromuscular | 2009 |
[Muscle relaxants in the ICU].
Topics: Androstanols; Atracurium; Critical Illness; Humans; Hypothermia, Induced; Intensive Care Units; Moto | 2009 |
Suxamethonium stands the test of time: it is too early to say goodbye.
Topics: Humans; Laryngismus; Neuromuscular Blockade; Neuromuscular Depolarizing Agents; Neuromuscular Juncti | 2009 |
Succinylcholine given by the tracheal route does not provide neuromuscular blockade.
Topics: Arthroscopy; Electromyography; Humans; Injections; Intubation, Intratracheal; Monitoring, Physiologi | 2010 |
Use of rocuronium-sugammadex, an alternative to succinylcholine, as a muscle relaxant during electroconvulsive therapy.
Topics: Aged; Androstanols; Electroconvulsive Therapy; Female; gamma-Cyclodextrins; Humans; Male; Middle Age | 2011 |
Prolonged neuromuscular paralysis following rapid-sequence intubation with succinylcholine.
Topics: Apnea; Butyrylcholinesterase; Female; Humans; Intubation, Intratracheal; Metabolism, Inborn Errors; | 2011 |
Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy.
Topics: Androstanols; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Electroconv | 2011 |
The influence of unrestricted use of sugammadex on clinical anaesthetic practice in a tertiary teaching hospital.
Topics: Adult; Aged; Aged, 80 and over; Androstanols; Anesthesia; Cholinesterase Inhibitors; Drug Utilizatio | 2012 |
[Experience on the use of sugammadex in a French university hospital].
Topics: Aged; Androstanols; Anesthesia, General; Atracurium; Drug Utilization; Female; France; gamma-Cyclode | 2012 |
Anesthesiology in the era of drug shortages: use of a succinylcholine infusion for a laparoscopic sigmoid colectomy due to a shortage of neostigmine.
Topics: Colectomy; Colon, Sigmoid; Female; Humans; Laparoscopy; Middle Aged; Neostigmine; Neuromuscular Bloc | 2013 |
Prolonged neuromuscular block due to cholinesterase depletion by plasmapheresis.
Topics: Adult; Cholinesterases; Female; Glomerulosclerosis, Focal Segmental; Graft Rejection; Humans; Isoqui | 2002 |
Increase in twitch force of the adductor pollicis muscle with stabilized preload at constant thumb abduction before and after administration of muscle relaxant.
Topics: Adult; Anesthesia, General; Female; Humans; Male; Muscle, Skeletal; Neuromuscular Blockade; Neuromus | 1999 |
The bispectral index declines during neuromuscular block in fully awake persons.
Topics: Alcuronium; Consciousness; Electroencephalography; Electromyography; Facial Muscles; Humans; Muscle | 2003 |
The bispectral index declines during neuromuscular block in fully awake persons.
Topics: Alcuronium; Consciousness; Electroencephalography; Electromyography; Facial Muscles; Humans; Muscle | 2003 |
The bispectral index declines during neuromuscular block in fully awake persons.
Topics: Alcuronium; Consciousness; Electroencephalography; Electromyography; Facial Muscles; Humans; Muscle | 2003 |
The bispectral index declines during neuromuscular block in fully awake persons.
Topics: Alcuronium; Consciousness; Electroencephalography; Electromyography; Facial Muscles; Humans; Muscle | 2003 |
The effect of ether on the neuromuscular block caused by succinylcholine.
Topics: Ether; Ethers; Neuromuscular Blockade; Neuromuscular Diseases; Paralysis; Succinylcholine | 1954 |
The mode of neuromuscular block caused by acetylcholine, nicotine, decamethonium and succinylcholine.
Topics: Acetylcholine; Decamethonium Compounds; Humans; Muscle Relaxants, Central; Neuromuscular Blockade; N | 1955 |
The influence of anticholinesterases on the neuromuscular block produced by suxamethonium.
Topics: Cholinesterase Inhibitors; Humans; Neostigmine; Neuromuscular Blockade; Physostigmine; Succinylcholi | 1956 |
The effect of tetraethylammonium (T.E.A.) on neuromuscular block caused by succinyldicholine and succinylmonocholine.
Topics: Humans; Neuromuscular Blockade; Succinylcholine; Tetraethylammonium | 1958 |
Posttetanic relief of neuromuscular block.
Topics: Decamethonium Compounds; Muscles; Neuromuscular Blockade; Succinylcholine | 1963 |
[PYRIDOSTIGMINE AS AN ANTAGONIST IN PROLONGED SUCCINYLCHOLINE- INDUCED NEUROMUSCULAR BLOCK].
Topics: Adjuvants, Anesthesia; Humans; Neuromuscular Blockade; Neuromuscular Diseases; Parasympathomimetics; | 1963 |
[STUDIES ON THE DIFFERENTIATION OF THE TYPE OF NEUROMUSCULAR BLOCK].
Topics: Anesthesia; Anesthesia, General; Anesthesiology; Animals; Apnea; Decamethonium Compounds; Dogs; Elec | 1962 |
[NEUROMUSCULAR BLOCK CAUSED BY ANTIBIOTICS. RELATIONSHIPS BETWEEN CURARE-LIKE DRUGS AND ANTIBIOTICS. EXPERIMENTS WITH ANTAGONISTS].
Topics: Anesthesia; Anesthesiology; Animals; Anti-Bacterial Agents; Curare; Dihydrostreptomycin Sulfate; Kan | 1964 |
HISTAMINE INDUCED MODIFICATION OF NEUROMUSCULAR BLOCKADE BY LEPTO- AND PACHYCURARES.
Topics: Animals; Anti-Allergic Agents; Decamethonium Compounds; Gallamine Triethiodide; Histamine; Histamine | 1964 |
NEUROMUSCULAR BLOCK AS A POSSIBLE MECHANISM OF DEATH IN AMPHETAMINE POISONING.
Topics: Carbachol; Curare; Dextroamphetamine; Injections; Injections, Intraperitoneal; Neostigmine; Neuromus | 1964 |
Paramedic-administered neuromuscular blockade improves prehospital intubation success in severely head-injured patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allied Health Personnel; Androstanols; Case-Control Stud | 2003 |
On succinylcholine, a neuromuscular blocking drug, and its synergism with TEPP.
Topics: Choline; Diphosphates; Drug Interactions; Humans; Neuromuscular Blockade; Organophosphorus Compounds | 1951 |
Genotyping the butyrylcholinesterase in patients with prolonged neuromuscular block after succinylcholine.
Topics: Adult; Aged; Aged, 80 and over; Butyrylcholinesterase; Child; Female; Genotype; Humans; Male; Mutati | 2005 |
Neostigmine-induced prolonged neuromuscular blockade in a patient with atypical pseudocholinesterase.
Topics: Butyrylcholinesterase; Cholinesterase Inhibitors; Cystoscopy; Humans; Male; Middle Aged; Neostigmine | 2005 |
[Butyrylcholinesterase deficiency: how to analyse the cholinesterase activity in small children?].
Topics: Age Factors; Anesthetics, Local; Butyrylcholinesterase; Cholinesterases; Dibucaine; Female; Genetic | 2006 |
A response to 'Airway rescue in acute upper airway obstruction using a ProSeal Laryngeal mask airway and an Aintree Catheter: a review of the ProSeal Laryngeal mask airway in the management of the difficult airway'.
Topics: Acute Disease; Airway Obstruction; Humans; Laryngeal Masks; Neuromuscular Blockade; Neuromuscular De | 2006 |
Depolarizing block is an endplate-muscular block, not a neuromuscular block.
Topics: Animals; Humans; Motor Endplate; Muscles; Neuromuscular Blockade; Neuromuscular Depolarizing Agents; | 2007 |
Comparative use of muscle relaxants and their reversal in three European countries: a survey in France, Germany and Great Britain.
Topics: Alcuronium; Cholinesterase Inhibitors; Drug Utilization; France; Germany; Humans; Intubation, Intrat | 1996 |
[Effects of melatonin on muscle contractility and neuromuscular blockade produced by muscle relaxants].
Topics: Animals; Calcium Channel Blockers; Drug Synergism; In Vitro Techniques; Male; Melatonin; Muscle Cont | 1997 |
Rocuronium and vecuronium.
Topics: Adolescent; Adult; Aged; Androstanols; Craniocerebral Trauma; Humans; Intracranial Pressure; Middle | 1997 |
Tacrine does not alter the potency of succinylcholine in the rat.
Topics: Administration, Oral; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Dose-Response Relations | 1997 |
Hyperkalaemic cardiac arrest following succinylcholine in a longterm intensive care patient.
Topics: Atracurium; Coronary Artery Bypass; Critical Care; Heart Arrest; Humans; Hyperkalemia; Immobilizatio | 1997 |
Twitch augmentation and train-of-four fade during onset of neuromuscular block after subclinical doses of suxamethonium.
Topics: Adult; Anesthesia, General; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Neuromus | 1997 |
Succinylcholine: pros and cons.
Topics: Child; Humans; Neuromuscular Blockade; Neuromuscular Depolarizing Agents; Succinylcholine | 1997 |
Rapid-sequence intubation with non-depolarizing muscle relaxants.
Topics: Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Humans; Intubation, Intratracheal; | 1997 |
Intubation success rates improve for an air medical program after implementing the use of neuromuscular blocking agents.
Topics: Adjuvants, Anesthesia; Adult; Air Ambulances; Anesthesia, Intravenous; Anesthetics, Local; Atropine; | 1998 |
Sevoflurane for predicted difficult tracheal intubation.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthetics, Inhalation; Female; Forecasting | 1998 |
Neuromuscular blocking and cardiovascular effects of Org 9487, a new short-acting aminosteroidal blocking agent, in anaesthetized animals and in isolated muscle preparations.
Topics: Adrenergic alpha-Agonists; Animals; Cats; Chickens; Cholinesterase Inhibitors; Dogs; Dose-Response R | 1998 |
Can rocuronium replace succinylcholine in a rapid-sequence induction of anaesthesia?
Topics: Analgesics, Opioid; Androstanols; Anesthesia, Intravenous; Anesthetics, Intravenous; Humans; Intubat | 1999 |
Marked prolongation of the succinylcholine effect two hours after neostigmine reversal of neuromuscular blockade in a patient with chronic renal insufficiency.
Topics: Aged; Carotid Stenosis; Cholinesterase Inhibitors; Endarterectomy, Carotid; Humans; Kidney Failure, | 1999 |
Prevention of succinylcholine fasciculations.
Topics: Androstanols; Atracurium; Fasciculation; Humans; Neuromuscular Blockade; Neuromuscular Depolarizing | 1998 |
Remifentanil's effect is not prolonged in a patient with pseudocholinesterase deficiency.
Topics: Adult; Analgesics, Opioid; Butyrylcholinesterase; Female; Humans; Neuromuscular Blockade; Neuromuscu | 1999 |
Premedication before intubation in UK neonatal units.
Topics: Anti-Anxiety Agents; Atropine; Benzodiazepines; Humans; Hypnotics and Sedatives; Infant, Newborn; In | 2000 |
Are fade and sustained post-tetanic facilitation characteristics of typical succinylcholine-induced block?
Topics: Humans; Neuromuscular Blockade; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Succinylc | 2001 |
Intralingual succinylcholine injection provides a rapid onset of muscle relaxation in an emergency.
Topics: Aged; Emergencies; Female; Humans; Injections; Neuromuscular Blockade; Neuromuscular Depolarizing Ag | 2001 |
Screening patients with prolonged neuromuscular blockade after succinylcholine and mivacurium.
Topics: Adolescent; Adult; Aged; Butyrylcholinesterase; Child; Child, Preschool; Female; Heterozygote; Homoz | 2002 |