Page last updated: 2024-11-04

succinylcholine and Myotonia

succinylcholine has been researched along with Myotonia in 24 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Myotonia: Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation of the muscle. Myotonia is a characteristic feature of MYOTONIC DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Succinylcholine should be avoided in any patient with known myotonia because of the possibility of an abnormal rigid response."7.65Prolonged muscle rigidity following administration of succinylcholine. ( Davis, GC, 1977)
"The findings include the mechanisms of the hyperkalemia after succinylcholine in patients with upregulation of acetylcholine receptors."4.84Neuromuscular and mitochondrial disorders: what is relevant to the anaesthesiologist? ( Driessen, JJ, 2008)
"Myotonic discharges in rats given 20, 25-diazacholesterol hydrochloride and fibrillation discharges in denervated rat muscle both were silenced by procaine hydrochloride, tetrodotoxin or ischemia, or potassium chloride (after initial activation)."3.66The effect of pharmacologic acetylcholine receptor on fibrillation and myotonia in rat skeletal muscle. ( Bertorini, TE; Brumback, RA; Engel, WK; Oliver, KL; Trotter, JL; Zirzow, GC, 1978)
"Succinylcholine should be avoided in any patient with known myotonia because of the possibility of an abnormal rigid response."3.65Prolonged muscle rigidity following administration of succinylcholine. ( Davis, GC, 1977)
"This contracture is not prevented or relieved by regional anaesthesia or muscle relaxants."2.38[Anesthesia in myotonia]. ( Lienhart, A, 1989)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199018 (75.00)18.7374
1990's4 (16.67)18.2507
2000's1 (4.17)29.6817
2010's0 (0.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Mohammed, SR1
Gafoor, S1
Panday, A1
PATERSON, IS1
Driessen, JJ1
Thiel, RE1
Azar, I1
Walts, LF1
Iaizzo, PA1
Lehmann-Horn, F1
Smith, JH1
Gronert, GA1
Rosenberg, H1
Shutack, JG1
Brumback, RA1
Bertorini, TE1
Engel, WK1
Trotter, JL1
Oliver, KL1
Zirzow, GC1
Mitchell, MM1
Ali, HH1
Savarese, JJ1
Davis, GC1
Lienhart, A1
Griffiths, IR1
Duncan, ID1
Harriman, DG1
Sumner, DW1
Ellis, FR1
Thomas, ET1
Dobkin, AB1
Dalal, FY1
Bennett, EJ1
Raj, PP1
Lee, DG1
Baraka, A1
Haddad, C1
Afifi, A1
Baroody, M1
Mizushima, N1
Sasaki, Y1
Suzuki, M1
Okuaki, A1
Kunimoto, K1
Abe, M1
Ota, M1
Yogosawa, T1
Nishiguchi, M1
Gibson, JA1
Gardiner, DM1
Britt, BA2
Gordon, RA1
Locher, WG1
Kalow, W1

Reviews

5 reviews available for succinylcholine and Myotonia

ArticleYear
Neuromuscular and mitochondrial disorders: what is relevant to the anaesthesiologist?
    Current opinion in anaesthesiology, 2008, Volume: 21, Issue:3

    Topics: Anesthesiology; Anesthetics, Inhalation; Anesthetics, Intravenous; Humans; Hyperkalemia; Malignant H

2008
The response of patients with neuromuscular disorders to muscle relaxants: a review.
    Anesthesiology, 1984, Volume: 61, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Curare; Hemiplegia; Humans; Hyperkalemia; Malignant Hyperthermia; Mul

1984
Neuromuscular blocking drugs.
    Otolaryngologic clinics of North America, 1981, Volume: 14, Issue:3

    Topics: Bradycardia; Cholinesterases; Gallamine Triethiodide; Heart Arrest; Humans; Hyperkalemia; Infant; In

1981
Variants of malignant hyperthermia. Special problems for the paediatric anaesthesiologist.
    Paediatric anaesthesia, 1996, Volume: 6, Issue:2

    Topics: Child; Child, Preschool; Death, Sudden, Cardiac; Female; Humans; Infant; Male; Malignant Hyperthermi

1996
[Anesthesia in myotonia].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Anesthesia; Contracture; Disease Susceptibility; Female; Humans; Hypercapnia; Male; Malignant Hypert

1989

Other Studies

19 other studies available for succinylcholine and Myotonia

ArticleYear
Acute myotonic reaction during succinylcholine anaesthesia.
    Practical neurology, 2023, Volume: 23, Issue:1

    Topics: Adult; Anesthesia; Female; Hand Strength; Humans; Myotonia; Myotonic Disorders; NAV1.4 Voltage-Gated

2023
Generalized myotonia following suxamethonium. A case report.
    British journal of anaesthesia, 1962, Volume: 34

    Topics: Humans; Myotonia; Myotonia Congenita; Succinylcholine

1962
The myotonic response to suxamethonium.
    British journal of anaesthesia, 1967, Volume: 39, Issue:10

    Topics: Adult; Anesthesia, General; Humans; Male; Myotonia; Myotonia Congenita; Succinylcholine; Sympathecto

1967
Anesthetic complications in muscle disorders.
    Anesthesiology, 1995, Volume: 82, Issue:5

    Topics: Anesthetics; Humans; Malignant Hyperthermia; Muscular Diseases; Myotonia; Succinylcholine

1995
Product label information for suxamethonium in the USA.
    Anaesthesia, 1994, Volume: 49, Issue:12

    Topics: Child; Contraindications; Drug Labeling; England; Humans; Muscular Dystrophies; Myotonia; Succinylch

1994
Myotonias and masseter spasm: not malignant hyperthermia?
    Anesthesiology, 1995, Volume: 83, Issue:6

    Topics: Animals; Goats; Humans; Malignant Hyperthermia; Masseter Muscle; Myotonia; Neuromuscular Depolarizin

1995
The effect of pharmacologic acetylcholine receptor on fibrillation and myotonia in rat skeletal muscle.
    Archives of neurology, 1978, Volume: 35, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Azacosterol; Bungarotoxins; Evoked Potentials; Ischemia; Male; Mus

1978
Myotonia and neuromuscular blocking agents.
    Anesthesiology, 1978, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Electric Stimulation; Electrophysiology; Evoked Potentia

1978
Prolonged muscle rigidity following administration of succinylcholine.
    Southern medical journal, 1977, Volume: 70, Issue:9

    Topics: Child; Female; Humans; Muscle Rigidity; Myotonia; Succinylcholine

1977
Myotonia in the dog: a report of four cases.
    The Veterinary record, 1973, Aug-18, Volume: 93, Issue:7

    Topics: Animals; Biopsy; Creatine Kinase; Cushing Syndrome; Dog Diseases; Dogs; Electrodes; Electromyography

1973
Malignant hyperpyrexia myopathy.
    The Quarterly journal of medicine, 1973, Volume: 42, Issue:168

    Topics: Adolescent; Adult; Anesthesia, General; Atrophy; Biopsy; Child; Child, Preschool; Female; Halothane;

1973
Untoward effects of muscle relaxant drugs.
    International anesthesiology clinics, 1972,Spring, Volume: 10, Issue:1

    Topics: Adjuvants, Anesthesia; Amyotrophic Lateral Sclerosis; Anesthesia, Inhalation; Anti-Bacterial Agents;

1972
Dystrophia myotonica: a multisystem disease.
    Canadian Anaesthetists' Society journal, 1972, Volume: 19, Issue:4

    Topics: Anesthesia; Atropine; Cholinesterases; Electromyography; Halothane; Humans; Male; Melanoma; Middle A

1972
Control of succinylcholine-induced myotonia by d-tubocurarine.
    Anesthesiology, 1970, Volume: 33, Issue:6

    Topics: Adult; Electromyography; Female; Humans; Myotonia; Succinylcholine; Tubocurarine

1970
[Cases of muscular rigidity caused by succinylcholine chloride].
    Masui. The Japanese journal of anesthesiology, 1968, Volume: 17, Issue:9

    Topics: Adult; Anesthesia, General; Blood Pressure; Child; Child, Preschool; Chlorides; Female; Humans; Male

1968
[Cases of myotonic syndromes due to succinylcholine].
    Masui. The Japanese journal of anesthesiology, 1968, Volume: 17, Issue:9

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Child; Humans; Hypertension; Hypothermia, Induced; Male;

1968
Malignant hypertonic hyperpyrexia syndrome.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:2

    Topics: Anesthesia, Inhalation; Child; Cyanosis; Female; Fever; Halothane; Humans; Hyperkalemia; Hypothermia

1969
Three cases of malignant hyperthermia with special consideration of management.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:2

    Topics: Acidosis; Adult; Anesthesia, Inhalation; Child, Preschool; Female; Fever; Halothane; Humans; Hyperka

1969
Hereditary aspects of malignant hyperthermia.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Age Factors; Anesthesia, Inhalation; Child; Child, Preschool; Female; Fever; Gene

1969