Page last updated: 2024-11-04

succinylcholine and Muscle Spasm

succinylcholine has been researched along with Muscle Spasm in 56 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Research Excerpts

ExcerptRelevanceReference
"We evaluated six boys who had developed isolated masseter muscle spasm following intravenous succinylcholine."7.66Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases. ( Flewellen, EH; Nelson, TE, 1982)
" In 1960, animal studies reported a transient increase in plasma potassium; further experiments in 1969 clearly demonstrated succinylcholine-induced hyperkalemia in burn patients."3.91A Chronology for the Identification and Disclosure of Adverse Effects of Succinylcholine. ( Desai, MS; Huang, L; Sang, CN, 2019)
"It has been claimed that the combination of halothane and succinylcholine, commonly used for anesthetic induction during short pediatric otolaryngologic procedures, is associated with a 1% incidence of masseter spasm (MS) which may be an early sign of malignant hyperthermia (MH)."3.68Masseter spasm and malignant hyperthermia: a retrospective review of a hospital-based pediatric otolaryngology practice. ( Brandom, BW; Chan, KH; Kosko, JR, 1992)
"A 4-year-old boy with Williams syndrome developed masseter spasm after halothane and suxamethonium."3.68Williams syndrome: masseter spasm during anaesthesia. ( Harrison, MJ; Patel, J, 1991)
"This retrospective study was undertaken to examine the management and outcome of children who developed isolated masseter muscle spasm (MMS) after the administration of intravenous succinylcholine during anesthetic induction."3.68Masseter muscle spasm in children: implications of continuing the triggering anesthetic. ( Bose, D; Cameron, CB; Littleford, JA; McKillop, C; Patel, LR, 1991)
" Following an uneventful induction of anaesthesia with halothane, nitrous oxide and O2, succinylcholine resulted in bilateral masseter muscle spasm and then, in rapid sequence, ventricular tachycardia and cardiac arrest."3.67Duchenne muscular dystrophy and malignant hyperthermia--two case reports. ( Stanley, TH; Wang, JM, 1986)
"We evaluated six boys who had developed isolated masseter muscle spasm following intravenous succinylcholine."3.66Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases. ( Flewellen, EH; Nelson, TE, 1982)
" Adverse effects of suxamethonium are generally related to its agonist mode of action."2.39Adverse effects of depolarising neuromuscular blocking agents. Incidence, prevention and management. ( Abel, M; Book, WJ; Eisenkraft, JB, 1994)
"Masseter spasm is often associated with severe rhabdomyolysis in patients with muscle dystrophy, especially Duchenne's dystrophy."2.38[Clinical features of malignant hyperthermia crisis]. ( Cornet, C; Laxenaire, MC; Moeller, R, 1989)
"When muscle spasm is induced with suxamethonium, malignant hyperpyrexia must be considered a probable diagnosis."1.27Suxamethonium spasm. A differential diagnostic conundrum. ( Ellis, FR; Halsall, PJ, 1984)
"In this Research Conference we define malignant hyperthermia, present its brief history, and describe the diagnostic procedures and directions of research in our laboratory."1.26Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion. ( Flewellen, EH; Nelson, TE, 1979)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199038 (67.86)18.7374
1990's15 (26.79)18.2507
2000's2 (3.57)29.6817
2010's1 (1.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, L1
Sang, CN1
Desai, MS1
Farbu, E1
Søfteland, E1
Bindoff, LA1
HOBIKA, JH1
CLARKE, BG1
MURTAGH, JA1
CAMPBELL, CJ1
Schwartz, L1
Rockoff, MA1
Koka, BV1
Ellis, FR1
Halsall, PJ1
Flewellen, EH3
Nelson, TE3
Famewo, CE1
Roy, R1
Hooda, S1
Kiran, S1
Thapa, D1
Chhabra, B1
Book, WJ1
Abel, M1
Eisenkraft, JB2
Gronert, GA1
Habre, W1
Sims, C1
Baraka, A2
Ramirez, JA1
Cheetham, ED1
Laurence, AS1
Hopkins, PM1
Adnet, P1
Busato, G1
Donlon, JV1
Newfield, P1
Sreter, F1
Ryan, JF1
Carballo, AS1
Kosko, JR1
Brandom, BW1
Chan, KH1
Jantzen, JP1
Eberle, B1
Gaida, BJ1
Hennes, HJ1
Otto, S1
Schäfer, M1
Kaplan, R1
Becker, M1
Broadman, L1
Meakin, G2
Derrington, MC1
Scott, JJ1
Patel, J1
Harrison, MJ1
Matthews, AJ1
Vernon, JM1
Littleford, JA1
Patel, LR1
Bose, D1
Cameron, CB1
McKillop, C1
Sinclair, G1
Cornet, C1
Moeller, R1
Laxenaire, MC1
Kancir, CB1
Wandrup, J1
Schwartz, N1
Raab, EL1
Carroll, JB1
Wang, JM1
Stanley, TH1
Muallem, M1
Karam, H1
Rosenberg, H1
Fletcher, JE1
VanDerSpek, AF1
Wilton, N1
Mostafa, SM1
Virdee, M1
Ricker, K1
Mertens, HG1
Kalow, W1
Britt, BA1
Barnes, PK1
Harrison, GG1
Coulter, C1
Edmunds, J1
Pyle, PO1
Miyazaki, H1
Yamanaka, I1
Sato, M1
Oira, K1
Takahashi, T1
Hogg, S1
Renwick, W1
Davies, DD1
Meadows, JC1
Pecoldowa, K1
Marrollo, E1
Mastroefano, MP1
Diamantis, W1
Kletzkin, M1
Thut, WH1
Davenport, HT1
Lavoie, G1

Reviews

3 reviews available for succinylcholine and Muscle Spasm

ArticleYear
Adverse effects of depolarising neuromuscular blocking agents. Incidence, prevention and management.
    Drug safety, 1994, Volume: 10, Issue:5

    Topics: Arrhythmias, Cardiac; Drug Labeling; Humans; Hyperkalemia; Incidence; Intraocular Pressure; Malignan

1994
[Severe side-effects of curare-like agents in children].
    Annales francaises d'anesthesie et de reanimation, 2000, Volume: 19 Suppl 2

    Topics: Child; Heart Arrest; Humans; Malignant Hyperthermia; Masseter Muscle; Neuromuscular Blocking Agents;

2000
[Clinical features of malignant hyperthermia crisis].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Anesthesia, General; Arrhythmias, Cardiac; Carbon Dioxide; Child; Child, Preschoo

1989

Other Studies

53 other studies available for succinylcholine and Muscle Spasm

ArticleYear
A Chronology for the Identification and Disclosure of Adverse Effects of Succinylcholine.
    Journal of anesthesia history, 2019, Volume: 5, Issue:3

    Topics: Animals; Drug Approval; Drug Development; Drug Industry; History, 20th Century; Humans; Hyperkalemia

2019
Anaesthetic complications associated with myotonia congenita: case study and comparison with other myotonic disorders.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:5

    Topics: Adult; Anesthesia; Electromyography; Female; Humans; Ion Channels; Myotonia Congenita; Myotonic Diso

2003
Use of neuromuscular blocking drugs to counteract thigh-adductor spasm induced by electrical shocks of obturator nerve during transurethral resection of bladder tumors.
    The Journal of urology, 1961, Volume: 85

    Topics: Curare; Humans; Obturator Nerve; Spasm; Succinylcholine; Thigh; Urinary Bladder Neoplasms

1961
Laryngeal spasm.
    Transactions of the American Laryngological, Rhinological and Otological Society, Inc, 1954, Volume: 4, Issue:58th Meeti

    Topics: Barbiturates; Curare; Humans; Laryngeal Diseases; Laryngismus; Larynx; Spasm; Succinylcholine

1954
Masseter spasm with anesthesia: incidence and implications.
    Anesthesiology, 1984, Volume: 61, Issue:6

    Topics: Anesthetics; Child; Child, Preschool; Creatine Kinase; Halothane; Humans; Infant; Malignant Hyperthe

1984
Suxamethonium spasm. A differential diagnostic conundrum.
    British journal of anaesthesia, 1984, Volume: 56, Issue:4

    Topics: Diagnosis, Differential; Disease Susceptibility; Humans; Malignant Hyperthermia; Spasm; Succinylchol

1984
Halothane-succinylcholine induced masseter spasm: indicative of malignant hyperthermia susceptibility?
    Anesthesia and analgesia, 1984, Volume: 63, Issue:7

    Topics: Caffeine; Child; Child, Preschool; Creatine Kinase; Female; Halothane; Humans; Male; Malignant Hyper

1984
Masseter spasm induced by succinylcholine in children: contracture testing for malignant hyperthermia: report of six cases.
    Canadian Anaesthetists' Society journal, 1982, Volume: 29, Issue:1

    Topics: Anesthesia; Caffeine; Child; Child, Preschool; Halothane; Humans; Male; Malignant Hyperthermia; Mass

1982
Masseter spasm induced by succinylcholine in children.
    Canadian Anaesthetists' Society journal, 1982, Volume: 29, Issue:4

    Topics: Adolescent; Anesthesia, General; Humans; Male; Masseter Muscle; Masticatory Muscles; Spasm; Succinyl

1982
[Masseter spasm].
    Canadian Anaesthetists' Society journal, 1982, Volume: 29, Issue:5

    Topics: Anesthetics; Child; Humans; Male; Masseter Muscle; Masticatory Muscles; Spasm; Succinylcholine

1982
Opisthotonus and thiopental.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:6

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Humans; Middle Aged; Muscle Rigidity; Mus

1995
Myotonias and masseter spasm: not malignant hyperthermia?
    Anesthesiology, 1995, Volume: 83, Issue:6

    Topics: Animals; Goats; Humans; Malignant Hyperthermia; Masseter Muscle; Myotonia; Neuromuscular Depolarizin

1995
Masseter spasm and elevated creatine kinase after intravenous induction in a child.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:4

    Topics: Anesthesia, Intravenous; Child; Creatine Kinase; Humans; Male; Malignant Hyperthermia; Masseter Musc

1996
Succinylcholine-induced "masseter spasm".
    Middle East journal of anaesthesiology, 1997, Volume: 14, Issue:2

    Topics: Humans; Malignant Hyperthermia; Masseter Muscle; Neuromuscular Depolarizing Agents; Spasm; Succinylc

1997
Suxamethonium, masseter spasm and later malignant hyperthermia.
    Anaesthesia, 1998, Volume: 53, Issue:11

    Topics: Adult; Anesthetics, Inhalation; Humans; Isoflurane; Male; Malignant Hyperthermia; Masseter Muscle; N

1998
Succinylcholine reverses spasm of the sphincter of Oddi.
    Anesthesiology, 1979, Volume: 50, Issue:6

    Topics: Ampulla of Vater; Biliary Tract Diseases; Humans; Spasm; Sphincter of Oddi; Succinylcholine

1979
Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion.
    Texas reports on biology and medicine, 1979, Volume: 38

    Topics: Anesthetics; Animals; Caffeine; Diagnosis, Differential; Disease Models, Animal; Halothane; Humans;

1979
Implications of masseter spasm after succinylcholine.
    Anesthesiology, 1978, Volume: 49, Issue:4

    Topics: Adult; Child; Female; Humans; Male; Masticatory Muscles; Spasm; Succinylcholine

1978
Aborted malignant hyperthermia: case report.
    Canadian Anaesthetists' Society journal, 1975, Volume: 22, Issue:2

    Topics: Acidosis; Adult; Anesthesia, General; Aspartate Aminotransferases; Bicarbonates; Creatine Kinase; Fe

1975
Masseter spasm and malignant hyperthermia: a retrospective review of a hospital-based pediatric otolaryngology practice.
    International journal of pediatric otorhinolaryngology, 1992, Volume: 23, Issue:1

    Topics: Anesthesia, General; Child; Family Health; Halothane; Humans; Incidence; Malignant Hyperthermia; Mas

1992
[The effect of muscle relaxants on masseter tone. An experimental study in an MH-susceptible swine model].
    Der Anaesthesist, 1992, Volume: 41, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Disease Susceptibility; Malignant Hyperthermia; Masseter Muscle; Sp

1992
Isolated masseter muscle spasm versus generalized rigidity?
    Anesthesia and analgesia, 1992, Volume: 75, Issue:1

    Topics: Adenoidectomy; Child, Preschool; Diagnosis, Differential; Halothane; Humans; Masseter Muscle; Muscle

1992
Masseter spasm after suxamethonium.
    British journal of anaesthesia, 1992, Volume: 68, Issue:4

    Topics: Adult; Child; Humans; Masseter Muscle; Spasm; Succinylcholine

1992
Masseteric muscle spasm.
    British journal of anaesthesia, 1991, Volume: 66, Issue:2

    Topics: Humans; Masseter Muscle; Spasm; Succinylcholine

1991
Williams syndrome: masseter spasm during anaesthesia.
    Anaesthesia, 1991, Volume: 46, Issue:2

    Topics: Anesthesia, Inhalation; Aortic Valve Stenosis; Child, Preschool; Face; Halothane; Humans; Intellectu

1991
Masseter spasm in Williams syndrome.
    Anaesthesia, 1991, Volume: 46, Issue:8

    Topics: Child, Preschool; Humans; Male; Masseter Muscle; Spasm; Succinylcholine

1991
Masseter muscle spasm in children: implications of continuing the triggering anesthetic.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:2

    Topics: Anesthesia, Inhalation; Arrhythmias, Cardiac; Carbon Dioxide; Child; Child, Preschool; Creatine Kina

1991
Masseter spasm following suxamethonium.
    British journal of hospital medicine, 1990, Volume: 44, Issue:5

    Topics: Adult; Female; Humans; Malignant Hyperthermia; Masseter Muscle; Pregnancy; Pregnancy, Ectopic; Spasm

1990
Calcium and other biochemical alterations induced by masseter spasm following suxamethonium.
    Acta anaesthesiologica Belgica, 1989, Volume: 40, Issue:3

    Topics: Biological Transport; Calcium; Child; Humans; Ions; Male; Masseter Muscle; Masticatory Muscles; Spas

1989
Masseter muscle spasm, succinylcholine, and strabismus surgery.
    Anesthesiology, 1988, Volume: 69, Issue:4

    Topics: Humans; Masseter Muscle; Masticatory Muscles; Spasm; Strabismus; Succinylcholine

1988
Underdosage with succinylcholine may lead to incorrect diagnosis of masseter spasm in children.
    Anesthesiology, 1988, Volume: 69, Issue:6

    Topics: Child; Diagnostic Errors; Humans; Masseter Muscle; Masticatory Muscles; Spasm; Succinylcholine

1988
Increased incidence of masseter spasm in children with strabismus anesthetized with halothane and succinylcholine.
    Anesthesiology, 1987, Volume: 67, Issue:4

    Topics: Child; Halothane; Humans; Masseter Muscle; Masticatory Muscles; Spasm; Strabismus; Succinylcholine

1987
Duchenne muscular dystrophy and malignant hyperthermia--two case reports.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:4

    Topics: Anesthesia, Inhalation; Child, Preschool; Fentanyl; Halothane; Humans; Hyperkalemia; Infant; Male; M

1986
Succinylcholine-triggered masseter spasm in a patient with trigeminal nerve palsy.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:11

    Topics: Humans; Male; Masseter Muscle; Masticatory Muscles; Middle Aged; Paralysis; Spasm; Succinylcholine;

1986
More about masseter spasm and malignant hyperthermia.
    Anesthesiology, 1985, Volume: 62, Issue:2

    Topics: Anesthesia; Child; Humans; Malignant Hyperthermia; Masseter Muscle; Muscle Rigidity; Spasm; Succinyl

1985
Suxamethonium spasm.
    British journal of anaesthesia, 1985, Volume: 57, Issue:3

    Topics: Humans; Malignant Hyperthermia; Spasm; Succinylcholine

1985
Severe muscle spasm during surgery.
    Anaesthesia, 1985, Volume: 40, Issue:10

    Topics: Drug Hypersensitivity; Female; Humans; Intraoperative Complications; Middle Aged; Muscles; Spasm; Su

1985
EMG phenomena in the "stiff-man" syndrome.
    Electroencephalography and clinical neurophysiology, 1968, Volume: 25, Issue:4

    Topics: Adult; Aminobutyrates; Diazepam; Electromyography; Female; Humans; Muscles; Procaine; Reflex; Spasm;

1968
Rigidity and malignant hyperthermia associated with anaesthesia.
    Humangenetik, 1970, Volume: 9, Issue:3

    Topics: Anesthesia, General; Animals; Calcium; Drug Hypersensitivity; Female; Fever; Halothane; Humans; Hydr

1970
Malignant hyperthermia--an investigation of three patients.
    Annals of the Royal College of Surgeons of England, 1971, Volume: 48, Issue:2

    Topics: Adenosine Triphosphatases; Anesthesia, General; Aspartate Aminotransferases; Body Temperature; Caffe

1971
Masseter spasm following intravenous suxamethonium: a case report.
    British journal of anaesthesia, 1973, Volume: 45, Issue:7

    Topics: Adult; Creatine Kinase; Female; Humans; Injections, Intravenous; Masticatory Muscles; Spasm; Succiny

1973
Althesin and malignant hyperpyrexia.
    British journal of anaesthesia, 1973, Volume: 45, Issue:10

    Topics: Anesthetics; Animals; Body Temperature; Drug Combinations; Halothane; Hydroxysteroids; Intubation, I

1973
An overdose of Parstelin.
    Anaesthesia, 1971, Volume: 26, Issue:4

    Topics: Adult; Diazepam; Humans; Male; Poisoning; Positive-Pressure Respiration; Spasm; Succinylcholine; Tac

1971
[Hyperventilation syndrome during general anesthesia].
    Masui. The Japanese journal of anesthesiology, 1972, Volume: 21, Issue:3

    Topics: Adult; Alkalosis, Respiratory; Anesthesia, General; Female; Halothane; Humans; Hyperventilation; Mal

1972
[Case of hyperthermia and muscle rigidity caused by succinylcholine].
    Masui. The Japanese journal of anesthesiology, 1971, Volume: 20, Issue:12

    Topics: Abdomen, Acute; Adjuvants, Anesthesia; Adult; Female; Fever; Humans; Spasm; Succinylcholine

1971
Hyperpyrexia during anaesthesia.
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:5

    Topics: Adult; Anesthesia, General; Arrhythmias, Cardiac; Body Temperature Regulation; Cortisone; Fever; Hum

1966
Hypertonic syndrome associated with suxamethonium administration.
    British journal of anaesthesia, 1970, Volume: 42, Issue:7

    Topics: Adult; Female; Humans; Muscle Contraction; Myositis; Spasm; Succinylcholine

1970
Muscle pain following suxamethonium.
    British journal of anaesthesia, 1971, Volume: 43, Issue:4

    Topics: Electromyography; Humans; Motor Neurons; Muscle Contraction; Muscular Diseases; Nerve Fibers, Myelin

1971
Experimental and clinical investigations of drugs limiting the rise of intraocular tension caused by succinylcholine. I. Investigations on the effects of succinylcholine on rabbit eye.
    Polish medical journal, 1968, Volume: 7, Issue:2

    Topics: Animals; Humans; Injections, Intravenous; Intraocular Pressure; Rabbits; Spasm; Succinylcholine

1968
[Prevention of succinylcholine-induced fasciculations and myalgias by administration of small doses of competitive muscle relaxants: clinical results].
    Acta anaesthesiologica, 1968, Volume: 19

    Topics: Humans; Muscle Relaxants, Central; Muscles; Muscular Diseases; Pain; Spasm; Succinylcholine

1968
Evaluation of muscle relaxant drugs by head-drop and by decerebrate rigidity.
    International journal of neuropharmacology, 1966, Volume: 5, Issue:4

    Topics: Animals; Carbamates; Carisoprodol; Cats; Chlordiazepoxide; Diazepam; Electromyography; Gallamine Tri

1966
Hyperpyrexia associated with succinylcholine-induced muscle rigidity: a case report.
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:5

    Topics: Bicarbonates; Blood Chemical Analysis; Child, Preschool; Fever; Gluconates; Heart Arrest; Heart Mass

1966
[Hyperpyrexia during general anaesthesia: a case report].
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:5

    Topics: Adult; Anesthesia, General; Apnea; Bicarbonates; Decamethonium Compounds; Fever; Heart Massage; Huma

1966