Page last updated: 2024-11-04

succinylcholine and Muscle Relaxation

succinylcholine has been researched along with Muscle Relaxation in 68 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"This study was conducted to compare recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex with succinylcholine during electroconvulsive therapy (ECT)."7.77Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy. ( Hoshi, H; Kadoi, Y; Nishida, A; Saito, S, 2011)
"During succinylcholine-induced muscle fasciculations, gastroesophageal barrier pressure in fasted adult dogs (n = 10) was compared by esophageal manometry with that in the same dogs with full stomachs."7.68Lower esophageal sphincter integrity is maintained during succinylcholine-induced fasciculations in dogs with "full" stomachs. ( Cook, WP; Schultetus, RR, 1990)
"Muscle fasciculation and postoperative myalgia were verified by means of a score."6.66["Self-taming": an alternative to the prevention of succinylcholine-induced pain]. ( Doehn, M; Lohmann, C; Viell, B; Wald-Oboussier, G, 1987)
"Five hundred patients treated during the 5-year period met inclusion criteria, 180 (36%) of whom required an adjustment of the succinylcholine dosing either above (119 patients) or below (61 patients) the 0."5.48Extreme variability in succinylcholine dose for muscle relaxation in electroconvulsive therapy. ( Aloysi, AS; Bryson, EO; Kellner, CH; Li, EH; Majeske, M, 2018)
"Five hundred consecutive unmedicated children received a minimum dose of 2 mg/kg intravenous succinylcholine after induction of anesthesia with halothane."5.07Jaw relaxation after a halothane/succinylcholine sequence in children. ( Hannallah, RS; Kaplan, RF, 1994)
"This study was conducted to compare recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex with succinylcholine during electroconvulsive therapy (ECT)."3.77Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy. ( Hoshi, H; Kadoi, Y; Nishida, A; Saito, S, 2011)
"During succinylcholine-induced muscle fasciculations, gastroesophageal barrier pressure in fasted adult dogs (n = 10) was compared by esophageal manometry with that in the same dogs with full stomachs."3.68Lower esophageal sphincter integrity is maintained during succinylcholine-induced fasciculations in dogs with "full" stomachs. ( Cook, WP; Schultetus, RR, 1990)
"This retrospective study examines the indications and the effects of 119 doses of succinylcholine or pancuronium given in the emergency department during a 24-month period to patients considered to have immediately life-threatening emergencies."3.67Neuromuscular blockade for critical patients in the emergency department. ( Clinton, JE; Roberts, DJ; Ruiz, E, 1986)
"ORG NC45 was compared with succinylcholine to produce muscle relaxation for short, intra-abdominal operations in 40 patients during nitrous oxide-oxygen-enflurane anaesthesia."3.66ORG NC45 for short intra-abdominal operations: a comparison with succinylcholine. ( Beran, DR; Gyasi, H; Melloni, C; Williams, A, 1983)
"The authors examined the thesis that a dose of dantrolene producing 95 per cent of maximal muscle relaxation (ED95) would effectively prevent or treat malignant hyperthermia (MH)."3.66Dantrolene dose response in malignant hyperthermia-susceptible (MHS) swine: method to obtain prophylaxis and therapeusis. ( Flewellen, EH; Nelson, TE, 1980)
"Sleep or muscle relaxation were achieved within 60 seconds in both groups, but time to achieve successful intubation was more than twice as fast with propofol (120 vs 260 seconds)."2.73Propofol compared with the morphine, atropine, and suxamethonium regimen as induction agents for neonatal endotracheal intubation: a randomized, controlled trial. ( Abdel-Latif, ME; Awad, J; Ghanta, S; Lui, K; Oei, J; Ravindranathan, H, 2007)
"Alfentanil 15 mu g/kg was not statistically significantly different from saline (P = 0."2.68Intubation without muscle relaxant: an alternative technique for rapid tracheal intubation. ( Teoh, GS; Wong, AK, 1996)
" The influence of prior suxamethonium administration on the potency of Org 9426 was studied also by constructing a dose-response curve."2.67Comparison of intubating conditions after administration of Org 9246 (rocuronium) and suxamethonium. ( Boules, Z; Clarke, RS; Cooper, R; Mirakhur, RK, 1992)
"Muscle fasciculation and postoperative myalgia were verified by means of a score."2.66["Self-taming": an alternative to the prevention of succinylcholine-induced pain]. ( Doehn, M; Lohmann, C; Viell, B; Wald-Oboussier, G, 1987)
"Five hundred patients treated during the 5-year period met inclusion criteria, 180 (36%) of whom required an adjustment of the succinylcholine dosing either above (119 patients) or below (61 patients) the 0."1.48Extreme variability in succinylcholine dose for muscle relaxation in electroconvulsive therapy. ( Aloysi, AS; Bryson, EO; Kellner, CH; Li, EH; Majeske, M, 2018)
"Hip fractures are a common injury affecting older individuals, especially women with osteoporosis."1.42Safe resumption of maintenance electroconvulsive therapy 12 days after surgical repair of hip fracture. ( Bryson, EO; Kellner, CH; Liebman, L; Nazarian, R, 2015)
" Use of a nerve stimulator facilitates more appropriate and individualized dosage of the neuromuscular blocking agents."1.26[Testing of neuromuscular function during anaesthesia (author's transl)]. ( Chraemmer-Jørgensen, B; Hicquet, J; Howardy-Hansen, P; Ording, H; Viby-Mogensen, J, 1980)
"During muscle fasciculation serum potassium fell by 0."1.26Biphasic change in serum potassium concentration following a single dose of succinylcholine chloride. ( Etchin, A; Rothschild, C; Tverskoy, M; Zakut, H, 1981)
"Diazepam pretreatment prevented muscle fasciculations, increases in serum potassium (K+) and creatinine phosphokinase (CPK) levels, increased heart rate and arterial pressure, and postoperative myalgia associated with SCh administration."1.26Diazepam prevents some adverse effects of succinylcholine. ( Fahmy, NR; Lappas, DG; Malek, NS, 1979)
"5 to 1 microgram/kg) than by increasing the dosage of thiopental."1.26The role of different components of balanced anaesthesia in tolerance to endotracheal intubation. ( Aromaa, U; Tammisto, T, 1977)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199041 (60.29)18.7374
1990's17 (25.00)18.2507
2000's5 (7.35)29.6817
2010's5 (7.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suparschi, V1
Sigaut, S1
Paugam-Burtz, C1
Bryson, EO3
Kellner, CH4
Li, EH2
Aloysi, AS1
Majeske, M1
Liebman, L1
Nazarian, R1
de Almeida, MC1
Pederneiras, SG1
Chiaroni, S1
de Souza, L1
Locks, GF1
Kadoi, Y1
Hoshi, H1
Nishida, A1
Saito, S1
Klostermann, F1
Gobbele, R1
Buchner, H1
Curio, G1
Messner, M1
Beese, U1
Romstöck, J1
Dinkel, M1
Tschaikowsky, K1
FAZIO, AN1
APOGI, E1
ASCIONE, J1
REICH, A1
IMO, K1
LAZAREVA, KN1
MATHEWSON, HS1
KONDZIELLA, W1
LORENZ, D1
KLOSS, J1
Schreiber, JU1
Fuchs-Buder, T1
Ghanta, S1
Abdel-Latif, ME1
Lui, K1
Ravindranathan, H1
Awad, J1
Oei, J1
Gyasi, H1
Williams, A1
Melloni, C1
Beran, DR1
Bertrand, M1
Lienhart, A1
Daloz, M1
Gendrel, H1
Dupuis, M1
Viars, P1
Gory, C1
Tannières-Ruffié, ML1
Vourc'h, G1
Varesi, M1
Toscano, R1
Chraemmer-Jørgensen, B1
Hicquet, J1
Howardy-Hansen, P1
Ording, H1
Viby-Mogensen, J1
Kitamura, K1
Katayama, K1
Kakemi, M1
Koizumi, T1
Hool, GJ1
Lawrence, PJ1
Sivaneswaran, N1
Jones, RS3
Gleed, RD1
Friesdorf, W1
Schultz, M1
Mehrkens, HH1
Kaufman, MP1
Rybicki, KJ1
Thompson, JD1
Fish, S1
Ruiz, E2
Zakut, H1
Tverskoy, M1
Etchin, A1
Rothschild, C1
Flewellen, EH1
Nelson, TE1
Doenicke, A1
Dittmann-Kessler, I1
Sramoto, A1
Beyer, E1
Strnad, J1
Schuh, FT1
Bissinger, U1
Beale, MD1
Lemert, R1
Pritchett, JT1
Bernstein, HJ1
Burns, CM1
Duc, T1
Roy, R1
Hannallah, RS1
Kaplan, RF1
Hansen, D1
Heitz, E1
Toussaint, S1
Schaffartzik, W1
Striebel, HW1
Booij, LH1
Wong, AK1
Teoh, GS1
Bevan, DR2
Stovner, J1
Holst-Larsen, H1
Harbo, S1
Fahmy, NR1
Malek, NS1
Lappas, DG1
Davies, DD1
Tammisto, T2
Aromaa, U1
Lunt, RL1
Kamm, G1
Reimherr, FW1
Hodges, MR1
Hill, GE1
Wong, KC1
Heckmann, R1
Wuersch, W1
Hashimoto, Y1
Shima, T1
Matsukawa, S1
Greenwood, B1
Blank, E1
Dodds, WJ1
Cooper, R1
Mirakhur, RK1
Clarke, RS1
Boules, Z1
Zhang, H1
Sloan, MH1
Lerman, J1
Bissonnette, B1
Toikka, O1
Ravagnan, R1
Pelosi, P1
Zocchi, C1
Ravagnan, I1
Russo, R1
Cesari, R1
Mastronardi, P1
De Vivo, P1
Esposito, O1
Giangreco, R1
Biancogiglio, IG1
Mazzarella, B1
van der Spek, AF1
Reynolds, PI1
Fang, WB1
Ashton-Miller, JA1
Stohler, CS1
Schork, MA1
Cook, WP1
Schultetus, RR1
Szalados, JE1
Donati, F1
Muir, AW1
Houston, J1
Marshall, RJ1
Bowman, WC1
Marshall, IG1
Leyser, KH1
Konietzke, D1
Hennes, HJ1
Kunjappan, VE1
Brown, EM1
Alexander, GD1
Artru, AA1
Maltby, JR1
Cassidy, M1
Nanji, GM1
Wald-Oboussier, G1
Lohmann, C1
Viell, B1
Doehn, M1
Roberts, DJ1
Clinton, JE1
Reilly, EL1
Kelley, JT1
Pena, YM1
Plötz, J1
Braun, J1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind, Randomized, Crossover Design Study To Compare The Rocuronium Reversal By Sugammadex To Succinylcholine For Electroconvulsive Therapy (ECT)[NCT03532178]Phase 244 participants (Actual)Interventional2019-01-01Completed
EEG-based Depth of Anesthesia-monitoring During General Anesthesia - Effects on Time to Wake-up and Post-operative Cognition[NCT04529304]100 participants (Anticipated)Interventional2021-01-08Recruiting
Bispectral Index: A Comparison of Bifrontal Montage Agreement[NCT04062240]15 participants (Actual)Observational2019-11-27Completed
Respiratory Effect of the LISA (Less Invasive Surfactant Administration) Method With Sedation by Propofol Versus Absence of Sedation: Double-blind Comparative Randomized Clinical Trial.[NCT04016246]Phase 3542 participants (Anticipated)Interventional2019-10-07Recruiting
Evaluation of Effectiveness of Two Different Doses of Mivacurium in Modified Rapid Sequence Intubation for Emergency Surgery ,Prospective Randomized Double Blind Study[NCT06072534]100 participants (Anticipated)Interventional2023-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Recovery Time of T1 to 90% Baseline

The time of neuromuscular recovery from sugammadex 4mg/kg dose reversal rocuronium at 0.6 mg/kg compared with traditionally used succinylcholine in electroconvulsive therapy (ECT). (NCT03532178)
Timeframe: 30 minutes

Interventionminutes (Mean)
Muscle Relaxant #16.79
Muscle Relaxant #210.97

Number of Participants With Treatment or Emergent Adverse Events of the Drugs

To document the side-effect profiles of sugammadex reversal of rocuronium and succhinylcholine in the ECT patient population (NCT03532178)
Timeframe: 24 hours after the procedure

,
InterventionParticipants (Count of Participants)
NauseaMyalgiaHeadache
Rocuronium + Sugammadex117
Succinylcholine + Normal Saline329

BIS Montage

"Degree of variability between the values produced by the BIS sensors in a bifrontal montage when monitored simultaneously by use of a Bland-Altmann plot. The average value of each timed pair was plotted against the difference between the pairs.~The BIS monitor outputs data on a scale of 0-100 in arbitrary units; 0 = an isoelectric state on EEG, 100 = fully awake patient. BIS values of 40-60 are thought to reduce the chance of patient recall during general anesthesia.~For the purpose of this study, a smaller confidence interval is better as it indicates a higher level of agreement between the two BIS sensors." (NCT04062240)
Timeframe: 10 minutes where both sensors are recording concurrently

Interventionunits on a scale (Mean)
Additional BIS Sensor0.01

Reviews

3 reviews available for succinylcholine and Muscle Relaxation

ArticleYear
[Neuromuscular blockades. Agents, monitoring and antagonism].
    Der Anaesthesist, 2006, Volume: 55, Issue:11

    Topics: Anesthesia; Humans; Monitoring, Intraoperative; Muscle Relaxation; Neuromuscular Blockade; Neuromusc

2006
Neuromuscular transmission and its pharmacological blockade. Part 3: Continuous infusion of relaxants and reversal and monitoring of relaxation.
    Pharmacy world & science : PWS, 1997, Volume: 19, Issue:1

    Topics: Electromyography; Humans; Infusions, Parenteral; Monitoring, Physiologic; Muscle Relaxants, Central;

1997
Neuromuscular blocking drugs: onset and intubation.
    Journal of clinical anesthesia, 1997, Volume: 9, Issue:6 Suppl

    Topics: Dose-Response Relationship, Drug; Humans; Metabolic Clearance Rate; Muscle Relaxation; Neuromuscular

1997

Trials

16 trials available for succinylcholine and Muscle Relaxation

ArticleYear
[Evaluation of tracheal intubation conditions in morbidly obese patients: a comparison of succinylcholine and rocuronium].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:1

    Topics: Adult; Androstanols; Body Weight; Cough; Diaphragm; Dose-Response Relationship, Drug; Female; Humans

2009
Propofol compared with the morphine, atropine, and suxamethonium regimen as induction agents for neonatal endotracheal intubation: a randomized, controlled trial.
    Pediatrics, 2007, Volume: 119, Issue:6

    Topics: Atropine; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infant

2007
[Clinical use of vecuronium during celioscopy].
    Annales francaises d'anesthesie et de reanimation, 1983, Volume: 2, Issue:1

    Topics: Adult; Anesthesia, General; Blood Gas Analysis; Female; Humans; Laparoscopy; Middle Aged; Muscle Rel

1983
[Comparative clinical study of the effects of vecuronium and suxamethonium during oto-rhino-laryngeal and tracheobronchial laser surgery].
    Annales francaises d'anesthesie et de reanimation, 1983, Volume: 2, Issue:1

    Topics: Adult; Aged; Bronchial Diseases; Female; Humans; Laser Therapy; Male; Middle Aged; Muscle Contractio

1983
Jaw relaxation after a halothane/succinylcholine sequence in children.
    Anesthesiology, 1994, Volume: 81, Issue:1

    Topics: Anesthesia; Child; Child, Preschool; Halothane; Humans; Infant; Jaw; Masseter Muscle; Muscle Relaxat

1994
Deep halothane anaesthesia compared with halothane-suxamethonium anaesthesia for tracheal intubation in young children.
    European journal of anaesthesiology, 1997, Volume: 14, Issue:1

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Pressure; Child, Preschool; Double-Blind Meth

1997
Intubation without muscle relaxant: an alternative technique for rapid tracheal intubation.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Alfentanil; Anesthetics, Intravenous; Cough; Double-Blind Method; Elective Surgic

1996
Comparison of intubating conditions after administration of Org 9246 (rocuronium) and suxamethonium.
    British journal of anaesthesia, 1992, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia; Dose-Response Relationship, Drug; Humans; Intubat

1992
[Efficacy of succinylcholine under hyperventilation].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1992, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Anesthesia, General; Blood Gas Analysis; Female; Humans; Hypocapnia; Male; Mastec

1992
Pharmacodynamics of high-dose vecuronium in children during balanced anesthesia.
    Anesthesiology, 1991, Volume: 74, Issue:4

    Topics: Anesthesia, Intravenous; Child; Child, Preschool; Dose-Response Relationship, Drug; Electromyography

1991
Spontaneous EMG activity for detection of arousal during general anaesthesia--comparison between recordings from frontal and neck musculature.
    European journal of anaesthesiology, 1991, Volume: 8, Issue:2

    Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Arousal; Electromyography; Enf

1991
Changes in resistance to mouth opening induced by depolarizing and non-depolarizing neuromuscular relaxants.
    British journal of anaesthesia, 1990, Volume: 64, Issue:1

    Topics: Analysis of Variance; Anesthesia, Inhalation; Child; Facial Muscles; Female; Humans; Isoflurane; Mal

1990
Effect of d-tubocurarine pretreatment on succinylcholine twitch augmentation and neuromuscular blockade.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Injections, Intravenous;

1990
[Vecuronium bromide and succinylcholine procedures in medial relaxation. A comparison of electromyography and clinical findings].
    Der Anaesthesist, 1989, Volume: 38, Issue:6

    Topics: Anesthesia; Electromyography; Humans; Laparoscopy; Muscle Relaxation; Pelvis; Postoperative Period;

1989
["Self-taming": an alternative to the prevention of succinylcholine-induced pain].
    Der Anaesthesist, 1987, Volume: 36, Issue:8

    Topics: Adult; Anesthesia, General; Drug Administration Schedule; Fasciculation; Female; Humans; Male; Middl

1987
[Serum myoglobin following intermittent administration of succinylcholine and the effect of dantrolene. Clinical studies of children in halothane anesthesia].
    Der Anaesthesist, 1985, Volume: 34, Issue:10

    Topics: Anesthesia; Child; Dantrolene; Halothane; Humans; Muscle Relaxation; Myoglobin; Preanesthetic Medica

1985

Other Studies

49 other studies available for succinylcholine and Muscle Relaxation

ArticleYear
Prolonged muscle relaxation following succinylcholine administration in a cirrhotic patient: A case report.
    European journal of anaesthesiology, 2019, Volume: 36, Issue:11

    Topics: Female; Humans; Liver Cirrhosis; Middle Aged; Muscle Relaxation; Neuromuscular Depolarizing Agents;

2019
Extreme variability in succinylcholine dose for muscle relaxation in electroconvulsive therapy.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2018, Volume: 26, Issue:4

    Topics: Adult; Electroconvulsive Therapy; Humans; Mental Disorders; Muscle Relaxation; Neuromuscular Blockad

2018
Safe resumption of maintenance electroconvulsive therapy 12 days after surgical repair of hip fracture.
    The journal of ECT, 2015, Volume: 31, Issue:2

    Topics: Aged; Electroconvulsive Therapy; Female; Hip Fractures; Humans; Muscle Relaxation; Neuromuscular Dep

2015
Muscle Relaxation With Succinylcholine in Electroconvulsive Therapy.
    Anesthesia and analgesia, 2016, Volume: 123, Issue:5

    Topics: Electroconvulsive Therapy; Humans; Muscle Relaxation; Succinylcholine

2016
Comparison of recovery times from rocuronium-induced muscle relaxation after reversal with three different doses of sugammadex and succinylcholine during electroconvulsive therapy.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: Androstanols; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Electroconv

2011
Dissociation of human thalamic and cortical SEP gating as revealed by intrathalamic recordings under muscle relaxation.
    Brain research, 2002, Dec-20, Volume: 958, Issue:1

    Topics: Action Potentials; Afferent Pathways; Aged; Electric Stimulation Therapy; Evoked Potentials, Somatos

2002
The bispectral index declines during neuromuscular block in fully awake persons.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:2

    Topics: Alcuronium; Consciousness; Electroencephalography; Electromyography; Facial Muscles; Humans; Muscle

2003
The bispectral index declines during neuromuscular block in fully awake persons.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:2

    Topics: Alcuronium; Consciousness; Electroencephalography; Electromyography; Facial Muscles; Humans; Muscle

2003
The bispectral index declines during neuromuscular block in fully awake persons.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:2

    Topics: Alcuronium; Consciousness; Electroencephalography; Electromyography; Facial Muscles; Humans; Muscle

2003
The bispectral index declines during neuromuscular block in fully awake persons.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:2

    Topics: Alcuronium; Consciousness; Electroencephalography; Electromyography; Facial Muscles; Humans; Muscle

2003
The use of succinylcholine chloride by continuous intravenous infusion for the production of muscular relaxation; report of 1,500 cases.
    Military medicine, 1954, Volume: 115, Issue:5

    Topics: Humans; Infusions, Intravenous; Muscle Relaxation; Succinylcholine

1954
[Clinical use of succinyl-asta; bis-choline succinate dichloride, a drug with ultra-short effect on muscle relaxation].
    Srpski arhiv za celokupno lekarstvo, 1957, Volume: 85, Issue:4

    Topics: Choline; Muscle Relaxation; Succinates; Succinic Acid; Succinylcholine

1957
[Advantages of succinyi-bis-choline chloride administration for long-term muscle relaxation].
    Der Anaesthesist, 1958, Volume: 7, Issue:7

    Topics: Choline; Humans; Muscle Relaxation; Succinylcholine

1958
[REGIONAL MUSCLE RELAXATION IN OPERATIONS ON THE EXTREMITIES].
    Vestnik khirurgii imeni I. I. Grekova, 1963, Volume: 91

    Topics: Arm Injuries; Extremities; Fracture Fixation; Humans; Leg Injuries; Muscle Relaxation; Succinylcholi

1963
THE ROLE OF MUSCLE RELAXATION IN SURGICAL ANALGESIA.
    The Journal-lancet, 1964, Volume: 84

    Topics: Analgesia; Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Humans; Mephenesin; Muscle Relax

1964
[A NEW METHOD FOR THE MEASUREMENT OF MUSCLE RELAXATION IN WHITE MICE].
    Archives internationales de pharmacodynamie et de therapie, 1964, Dec-01, Volume: 152

    Topics: Animals; Chlorpromazine; Mephenesin; Meprobamate; Mice; Morphine; Muscle Relaxants, Central; Muscle

1964
[Reposition of fractures and luxations in complete muscle relaxation].
    Monatsschrift fur Unfallheilkunde und Versicherungsmedizin, 1955, Volume: 58, Issue:1

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Barbiturates; Fractures, Bone; Humans; Joint Disloc

1955
ORG NC45 for short intra-abdominal operations: a comparison with succinylcholine.
    Canadian Anaesthetists' Society journal, 1983, Volume: 30, Issue:2

    Topics: Adult; Electric Stimulation; Female; Humans; Intubation, Intratracheal; Laparoscopy; Movement; Muscl

1983
[Fazadinium in surgery of the gallbladder and the bile ducts].
    Chirurgia italiana, 1982, Volume: 34, Issue:6

    Topics: Adult; Aged; Bile Duct Diseases; Drug Evaluation; Female; Gallbladder Diseases; Heart Rate; Homeosta

1982
[Testing of neuromuscular function during anaesthesia (author's transl)].
    Anesthesie, analgesie, reanimation, 1980, Volume: 37, Issue:3-4

    Topics: Anesthesiology; Electric Stimulation; Humans; Intraoperative Period; Monitoring, Physiologic; Muscle

1980
[Effect of serum cholinesterase activity on muscle relaxation by succinylcholine in rats].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1984, Volume: 104, Issue:4

    Topics: Animals; Cholinesterases; Male; Muscle Contraction; Muscle Relaxation; Rats; Rats, Inbred Strains; S

1984
Acute rhabdomyolytic renal failure due to suxamethonium.
    Anaesthesia and intensive care, 1984, Volume: 12, Issue:4

    Topics: Acute Kidney Injury; Aged; Anesthesia; Humans; Male; Muscle Relaxation; Postoperative Complications;

1984
Effect of prior administration of suxamethonium on non-depolarising muscle relaxants in the dog.
    Research in veterinary science, 1984, Volume: 36, Issue:1

    Topics: Alcuronium; Anesthesia, Inhalation; Animals; Dogs; Drug Interactions; Gallamine Triethiodide; Inject

1984
[A simple method for determining and registering the degree of relaxation].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1984, Volume: 19, Issue:2

    Topics: Anesthesia; Electrocardiography; Humans; Monitoring, Physiologic; Muscle Contraction; Muscle Relaxat

1984
Muscular contraction reflexly relaxes tracheal smooth muscle in dogs.
    Respiration physiology, 1984, Volume: 56, Issue:1

    Topics: Animals; Capsaicin; Dogs; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Periodicity; Reflex

1984
Succinylcholine for endotracheal intubation.
    Annals of emergency medicine, 1982, Volume: 11, Issue:10

    Topics: Adult; Child; Emergencies; Female; Humans; Intubation, Intratracheal; Male; Middle Aged; Muscle Rela

1982
Biphasic change in serum potassium concentration following a single dose of succinylcholine chloride.
    Clinical and experimental obstetrics & gynecology, 1981, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Fasciculation; Female; Humans; Male; Middle Aged;

1981
Dantrolene dose response in malignant hyperthermia-susceptible (MHS) swine: method to obtain prophylaxis and therapeusis.
    Anesthesiology, 1980, Volume: 52, Issue:4

    Topics: Animals; Dantrolene; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Lactates;

1980
[Etomidate and suxamethonium. The duration of relaxation and pseudocholinesterase activity. A clinical experimental study (author's transl)].
    Der Anaesthesist, 1980, Volume: 29, Issue:3

    Topics: Adult; Anesthesia, General; Butyrylcholinesterase; Cholinesterases; Diazepam; Etomidate; Humans; Imi

1980
[Biphasic neuromuscular block - its diagnosis and importance in practice].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1980, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Aged; Anesthesia; Electric Stimulation; Female; Humans; Male; Middle Aged; Muscle

1980
[Haemodilution and duration of action of muscle relaxants (author's transl)].
    Der Anaesthesist, 1981, Volume: 30, Issue:1

    Topics: Cardiac Output; Hemodilution; Humans; Motor Endplate; Muscle Contraction; Muscle Relaxation; Pancuro

1981
Different onset times of succinylcholine-induced neuromuscular blockade at the adductor pollicis and stapedius muscles.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:6

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Humans; Ketamin

1995
Skeletal muscle relaxation in patients undergoing electroconvulsive therapy.
    Anesthesiology, 1994, Volume: 80, Issue:4

    Topics: Adolescent; Adult; Drug Administration Schedule; Electroconvulsive Therapy; Humans; Middle Aged; Mus

1994
Assessment of relaxation in clinical practice. Methods for routine and research.
    Acta anaesthesiologica Scandinavica. Supplementum, 1978, Volume: 70

    Topics: Humans; Infusions, Parenteral; Muscle Contraction; Muscle Relaxation; Nerve Block; Research; Succiny

1978
Diazepam prevents some adverse effects of succinylcholine.
    Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Anesthesia; Creatine Kinase; Diazepam; Fasciculation; Female; Humans; Intubation,

1979
Regurgitation and aspiration.
    British journal of anaesthesia, 1979, Volume: 51, Issue:8

    Topics: Adult; Anesthesia, Inhalation; Gastroesophageal Reflux; Humans; Inhalation; Muscle Relaxation; Phary

1979
The role of different components of balanced anaesthesia in tolerance to endotracheal intubation.
    Annales chirurgiae et gynaecologiae. Supplementum, 1977, Volume: 66, Issue:5

    Topics: Adult; Anesthesia; Female; Fentanyl; Humans; Intubation, Intratracheal; Male; Middle Aged; Muscle Re

1977
[The succinyl-choline drip as a muscle relaxant for ether-air anesthesia (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1976, Nov-19, Volume: 118, Issue:47

    Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Child; Child, Preschool; Costs and Cost Analysis; D

1976
Prolongation of muscle relaxant effects by lithium carbonate.
    The American journal of psychiatry, 1977, Volume: 134, Issue:2

    Topics: Animals; Dogs; Drug Synergism; Lithium; Muscle Contraction; Muscle Relaxation; Neuromuscular Junctio

1977
A method for recording evoked electrical and mechanical activity of muscle in the intact dog.
    Research in veterinary science, 1977, Volume: 23, Issue:1

    Topics: Alcuronium; Anesthesia; Animals; Atropine; Dogs; Electric Stimulation; Electromyography; Female; Mus

1977
Effect of plasma-cholinesterase preparation on the phase II block of succinylcholine chloride in man.
    The Tohoku journal of experimental medicine, 1977, Volume: 122, Issue:3

    Topics: Adult; Cholinesterases; Edrophonium; Humans; Muscle Relaxation; Succinylcholine

1977
Nicotine stimulates esophageal peristaltic contractions in cats by a central mechanism.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 1

    Topics: Animals; Cats; Deglutition; Electromyography; Esophagus; Female; Hexamethonium; Hexamethonium Compou

1992
[Electromyographic evaluation of muscle relaxation in leptonarcosis with depolarizing muscle relaxants in bolus].
    Minerva anestesiologica, 1991, Volume: 57, Issue:9

    Topics: Electromyography; Humans; Muscle Relaxation; Neuroleptanalgesia; Succinylcholine

1991
[Tracheal intubation: evaluation of muscle relaxation with mivacurium versus succinylcholine].
    Minerva anestesiologica, 1991, Volume: 57, Issue:9

    Topics: Humans; Intubation, Intratracheal; Isoquinolines; Mivacurium; Muscle Relaxation; Neuromuscular Nonde

1991
Lower esophageal sphincter integrity is maintained during succinylcholine-induced fasciculations in dogs with "full" stomachs.
    Anesthesia and analgesia, 1990, Volume: 70, Issue:4

    Topics: Animals; Dogs; Esophagogastric Junction; Fasciculation; Manometry; Muscle Relaxation; Pressure; Stom

1990
A comparison of the neuromuscular blocking and autonomic effects of two new short-acting muscle relaxants with those of succinylcholine in the anesthetized cat and pig.
    Anesthesiology, 1989, Volume: 70, Issue:3

    Topics: Anesthesia; Animals; Autonomic Nervous System; Cats; Dose-Response Relationship, Drug; Female; Hemod

1989
Interactions between pipecuronium and suxamethonium in the dog.
    Research in veterinary science, 1987, Volume: 43, Issue:3

    Topics: Androstane-3,17-diol; Androstanols; Animals; Dogs; Drug Interactions; Female; Muscle Contraction; Mu

1987
Rapid sequence induction using vecuronium.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:5

    Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Female; Fentanyl; Humans; Intubation, Int

1986
Muscle relaxation with succinylcholine or vecuronium does not alter the rate of CSF production or resistance to reabsorption of CSF in dogs.
    Anesthesiology, 1988, Volume: 68, Issue:3

    Topics: Animals; Cerebrospinal Fluid; Dogs; Muscle Contraction; Muscle Relaxation; Succinylcholine; Vecuroni

1988
Blind nasotracheal intubation using succinylcholine.
    Anesthesiology, 1988, Volume: 69, Issue:6

    Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Intubation, Intratracheal; Male; Muscle Relaxa

1988
Neuromuscular blockade for critical patients in the emergency department.
    Annals of emergency medicine, 1986, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Aged; Blood Pressure; Child; Child, Preschool; Emergencies; Female; Heart Rate; H

1986
Failure of Pavulon to consistently provide adequate EMG attenuation for recording electrocerebral inactivity.
    Clinical EEG (electroencephalography), 1985, Volume: 16, Issue:2

    Topics: Adult; Aged; Brain; Child, Preschool; Electroencephalography; Electromyography; Female; Humans; Male

1985