succinylcholine has been researched along with Morbid Obesity in 12 studies
Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We used published models to simulate the duration of unresponsiveness and ventilatory depression using a common induction technique with predicted rates of oxygen desaturation in various size patients and explored to what degree rapid reversal of rocuronium-induced neuromuscular blockade with sugammadex might improve the return of spontaneous ventilation in CICV situations." | 3.83 | The Myth of Rescue Reversal in "Can't Intubate, Can't Ventilate" Scenarios. ( Brewer, L; Johnson, KB; Kopman, AF; LaPierre, C; Naguib, M, 2016) |
| "Morbid obesity is associated with a reduction in time to desaturate during apnoea following standard pre-oxygenation and induction of anaesthesia." | 2.70 | Effectiveness of continuous positive airway pressure to enhance pre-oxygenation in morbidly obese women. ( Berthoud, MC; Cressey, DM; Reilly, CS, 2001) |
| "Succinylcholine is a paralytic agent regularly utilized in anesthesia." | 1.35 | Succinylcholine: a drug to avoid in bariatric surgery. ( Conner, J; Dutson, E; Jensen, C; Lewis, CE; Mehran, A; Tejirian, T, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naguib, M | 1 |
| Brewer, L | 1 |
| LaPierre, C | 1 |
| Kopman, AF | 1 |
| Johnson, KB | 1 |
| Tejirian, T | 1 |
| Lewis, CE | 1 |
| Conner, J | 1 |
| Jensen, C | 1 |
| Dutson, E | 1 |
| Mehran, A | 1 |
| de Almeida, MC | 1 |
| Pederneiras, SG | 1 |
| Chiaroni, S | 1 |
| de Souza, L | 1 |
| Locks, GF | 1 |
| Brodsky, JB | 3 |
| Lemmens, HJ | 2 |
| Schreiber, JU | 1 |
| Fuchs-Buder, T | 1 |
| Carron, M | 1 |
| Freo, U | 1 |
| Ori, C | 1 |
| Dewachter, P | 1 |
| Mouton-Faivre, C | 1 |
| Emala, CW | 1 |
| Beloucif, S | 1 |
| Pösö, T | 1 |
| Kesek, D | 1 |
| Winsö, O | 1 |
| Andersson, S | 1 |
| Foster, PE | 1 |
| Nafiu, O | 1 |
| Cressey, DM | 1 |
| Berthoud, MC | 1 |
| Reilly, CS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| EPO2-A: Evaluation of Different Pre-Oxygenation Condition in Morbid Obesity: Effect of Position and Positive Pressure Ventilation During General Anesthesia Induction[NCT02590406] | 50 participants (Actual) | Interventional | 2015-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Evaluation of the maximum expired oxygen fraction obtained in the two groups (NCT02590406)
Timeframe: After 3 minutes of pre-oxygenation
| Intervention | Maximum expired fraction of oxygen obtai (Mean) |
|---|---|
| Beach Chair (BC) and ZEEP | 0.89 |
| Reverse Trendelenburg and NIPPV | 0.91 |
Evaluation of the minimal saturation obtained after the resumption of the ventilation (NCT02590406)
Timeframe: After the end of the Non-hypoxic apnea time
| Intervention | percent (Mean) |
|---|---|
| Beach Chair (BC) and ZEEP | 83.6 |
| Reverse Trendelenburg and NIPPV | 85.3 |
Change of Non-hypoxic apnea time in obese patient during a General Anesthesia induction, as a result of different pre-oxygenation position and ventilation mode; 1-Beach Chair and No positive pressure ventilation, 2-Reverse Trendelenburg and positive pressure ventilation and PEEP. End of measure time frame is 5 minutes after intubation (NCT02590406)
Timeframe: After a 3 minutes pre-oxygenation period
| Intervention | seconds (Mean) |
|---|---|
| Beach Chair (BC) and ZEEP | 216.7 |
| Reverse Trendelenburg and NIPPV | 258.2 |
(NCT02590406)
Timeframe: Evaluation of the time needed to the beginning of the ventilation to the moment where the saturation is 97%
| Intervention | seconds (Mean) |
|---|---|
| Beach Chair (BC) and ZEEP | 88.4 |
| Reverse Trendelenburg and NIPPV | 68 |
Evaluation of time needed to obtain an expired fraction of oxygen of > 0,9 in the two groups during the pre-oxygenation (NCT02590406)
Timeframe: During the pre-oxygenation period
| Intervention | seconds (Mean) |
|---|---|
| Beach Chair (BC) and ZEEP | 145.3 |
| Reverse Trendelenburg and NIPPV | 85.1 |
3 trials available for succinylcholine and Morbid Obesity
| Article | Year |
|---|---|
[Evaluation of tracheal intubation conditions in morbidly obese patients: a comparison of succinylcholine and rocuronium].
Topics: Adult; Androstanols; Body Weight; Cough; Diaphragm; Dose-Response Relationship, Drug; Female; Humans | 2009 |
The dose of succinylcholine in morbid obesity.
Topics: Adult; Anesthesia, General; Body Mass Index; Body Weight; Double-Blind Method; Female; Gastric Bypas | 2006 |
Effectiveness of continuous positive airway pressure to enhance pre-oxygenation in morbidly obese women.
Topics: Adult; Anesthesia, General; Apnea; Blood Pressure; Body Mass Index; Female; Heart Rate; Humans; Intu | 2001 |
9 other studies available for succinylcholine and Morbid Obesity
| Article | Year |
|---|---|
The Myth of Rescue Reversal in "Can't Intubate, Can't Ventilate" Scenarios.
Topics: Adult; Androstanols; Anesthesia Recovery Period; Anesthesia, General; Biomarkers; Body Mass Index; C | 2016 |
Succinylcholine: a drug to avoid in bariatric surgery.
Topics: Adult; Female; Gastric Bypass; Humans; Intubation, Intratracheal; Length of Stay; Muscular Diseases; | 2009 |
Succinylcholine and morbid obesity: the debate continues...
Topics: Bariatric Surgery; Humans; Neuromuscular Depolarizing Agents; Obesity, Morbid; Succinylcholine | 2010 |
Succinylcholine: the dilemma with the evidence: comment on: Tejirian T, Lewis CE, Conner J et al. Succinylcholine: a drug to avoid in bariatric surgery. Obes Surg 2009; 19: 534-6.
Topics: Gastric Bypass; Humans; Muscular Diseases; Neuromuscular Depolarizing Agents; Obesity, Morbid; Succi | 2010 |
Succinylcholine in morbidly obese patients: another interesting advantage.
Topics: Bariatric Surgery; Female; Gastric Bypass; Humans; Muscular Diseases; Neuromuscular Depolarizing Age | 2011 |
Case scenario: bronchospasm during anesthetic induction.
Topics: Adult; Albuterol; Anesthesia; Anesthetics, Intravenous; Anti-Inflammatory Agents; Bronchial Spasm; B | 2011 |
Volatile rapid sequence induction in morbidly obese patients.
Topics: Adolescent; Adult; Aged; Alfentanil; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, I | 2011 |
Succinylcholine and morbid obesity.
Topics: Adult; Female; Humans; Intubation, Intratracheal; Male; Middle Aged; Neuromuscular Depolarizing Agen | 2003 |
Morbid obesity: a risk factor for maternal mortality.
Topics: Adult; Airway Obstruction; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, General; Anesth | 2007 |