succinylcholine has been researched along with Intracranial Aneurysm in 7 studies
Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.
Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (
| Excerpt | Relevance | Reference |
|---|---|---|
| "Succinylcholine-induced hyperkalemia has been reported to occur in many neurological disorders including subarachnoid hemorrhage." | 3.68 | Succinylcholine does not increase serum potassium levels in patients with acutely ruptured cerebral aneurysms. ( Gelb, AW; Mahendran, B; Manninen, PH; Merchant, RN, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwatsuki, N | 1 |
| Kuroda, N | 1 |
| Amaha, K | 1 |
| Iwatsuki, K | 1 |
| Kovarik, WD | 1 |
| Mayberg, TS | 1 |
| Lam, AM | 1 |
| Mathisen, TL | 1 |
| Winn, HR | 1 |
| Manninen, PH | 1 |
| Mahendran, B | 1 |
| Gelb, AW | 1 |
| Merchant, RN | 1 |
| Fink, M | 1 |
| Abrams, R | 1 |
| Yamamuro, M | 1 |
| Honda, T | 1 |
| Aitken, RR | 1 |
| Drake, CG | 1 |
| Campkin, TV | 1 |
| Dallas, SH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-Blind, Randomized, Crossover Design Study To Compare The Rocuronium Reversal By Sugammadex To Succinylcholine For Electroconvulsive Therapy (ECT)[NCT03532178] | Phase 2 | 44 participants (Actual) | Interventional | 2019-01-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The time of neuromuscular recovery from sugammadex 4mg/kg dose reversal rocuronium at 0.6 mg/kg compared with traditionally used succinylcholine in electroconvulsive therapy (ECT). (NCT03532178)
Timeframe: 30 minutes
| Intervention | minutes (Mean) |
|---|---|
| Muscle Relaxant #1 | 6.79 |
| Muscle Relaxant #2 | 10.97 |
To document the side-effect profiles of sugammadex reversal of rocuronium and succhinylcholine in the ECT patient population (NCT03532178)
Timeframe: 24 hours after the procedure
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Nausea | Myalgia | Headache | |
| Rocuronium + Sugammadex | 1 | 1 | 7 |
| Succinylcholine + Normal Saline | 3 | 2 | 9 |
1 review available for succinylcholine and Intracranial Aneurysm
| Article | Year |
|---|---|
Succinylcholine does not change intracranial pressure, cerebral blood flow velocity, or the electroencephalogram in patients with neurologic injury.
Topics: Adult; Aneurysm, Ruptured; Animals; Brain Edema; Cerebrovascular Circulation; Electroencephalography | 1994 |
6 other studies available for succinylcholine and Intracranial Aneurysm
| Article | Year |
|---|---|
Succinylcholine-induced hyperkalemia in patients with ruptured cerebral aneurysms.
Topics: Adult; Aged; Body Weight; Female; Hemiplegia; Humans; Hyperkalemia; Intracranial Aneurysm; Male; Mid | 1980 |
Succinylcholine does not increase serum potassium levels in patients with acutely ruptured cerebral aneurysms.
Topics: Adult; Female; Humans; Hyperkalemia; Intracranial Aneurysm; Male; Middle Aged; Potassium; Rupture, S | 1990 |
Answers to questions frequently asked about ECT.
Topics: Age Factors; Anesthesia, Intravenous; Brain Damage, Chronic; Brain Neoplasms; Depression; Electrocon | 1972 |
[Rupture of cerebral aneurysm during anesthesia].
Topics: Adult; Anesthesia, General; Blood Pressure; Female; Humans; Intracranial Aneurysm; Male; Middle Aged | 1973 |
A technique of anesthesia with induced hypotension for surgical correction of intracranial aneurysms.
Topics: Anesthesia, General; Blood Pressure Determination; Female; Halothane; Humans; Hypotension, Controlle | 1974 |
Elective circulatory arrest in neurosurgical operations.
Topics: Adolescent; Adult; Aneurysm; Angiomatosis; Aorta; Atropine; Blood Circulation; Brain; Catheterizatio | 1968 |