succinylcholine and Hypoxia studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Research Excerpts

Excerpt	Relevance	Reference
"To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane."	7.67	Mechanisms of succinylcholine-induced arrhythmias in hypoxic or hypoxic:hypercarbic dogs. ( Butler, BD; Katz, J; Leiman, BC, 1987)
"(1) To investigate changes in arterial oxygen saturation via pulse oximeter (SpO2) during apnea and after reinstitution of manual ventilation at SpO2 of 95% or 90% following rapid sequence induction of anesthesia in children after 2-minute preoxygenation; (2) to determine whether the setting of a safe threshold of apneic period to an SpO2 of 95% is appropriate in children during anesthetic induction; and (3) to evaluate the influences of age, body weight, and height on the time from the start of apnea to SpO2 of 95%."	5.08	Study of the safe threshold of apneic period in children during anesthesia induction. ( An, G; Deng, XM; Liao, X; Luo, LK; Tong, SY; Xue, FS, 1996)
"To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane."	3.67	Mechanisms of succinylcholine-induced arrhythmias in hypoxic or hypoxic:hypercarbic dogs. ( Butler, BD; Katz, J; Leiman, BC, 1987)
"Adult patients with head injuries were prospectively enrolled over a 1-year period by using the following inclusion criteria: Glasgow Coma Scale score of 3 to 8, transport time of greater than 10 minutes, and inability to intubate without RSI."	2.70	Paramedic-performed rapid sequence intubation of patients with severe head injuries. ( Bailey, D; Davis, D; Hoyt, D; Marshall, L; Ochs, M; Rosen, P, 2002)
"The use of Roc was associated with hypoxemia prior to RSI and VL."	1.48	Peri-intubation factors affecting emergency physician choice of paralytic agent for rapid sequence intubation of trauma patients. ( Caputo, ND; Donner, L; Kanter, M; Lott, C; West, JR, 2018)
"Succinylcholine was used in 420 (88%) patients."	1.36	Anesthetic management of the pediatric bleeding tonsil. ( Fields, RG; Gencorelli, FJ; Litman, RS, 2010)
"The arterial hypoxemia developed independently of the decerebration; however, dogs that demonstrated decerebrate posturing exhibited significantly larger decreases in Pa02 than dogs that did not (P less than 0."	1.27	Amelioration of hypoxemia by neuromuscular blockade following brain injury. ( Millis, RM; Trouth, CO; Wood, DH, 1985)
"In the absence of Ca(2+), acid, anoxia, and interruption of flow provoked receptor depression while receptor excitation induced by ACh and KCl persisted."	1.25	Pharmacology of pH effects on carotid body chemoreceptors in vitro. ( Eyzaguirre, C; Zapata, P, 1968)

Research

Studies (39)

Authors

Clinical Trials (6)

Trial Overview

Trial Outcomes

Number of Participants Exhibiting Desaturation >5%

Timeframe	Studies, this research(%)	All Research%
pre-1990	26 (66.67)	18.7374
1990's	5 (12.82)	18.2507
2000's	3 (7.69)	29.6817
2010's	4 (10.26)	24.3611
2020's	1 (2.56)	2.80

Authors	Studies
Gil-Jardiné, C	1
Jabre, P	1
Adnet, F	1
Nicol, T	1
Ecollan, P	1
Guihard, B	1
Ferdynus, C	1
Bocquet, V	1
Combes, X	1
West, JR	1
Lott, C	1
Donner, L	1
Kanter, M	1
Caputo, ND	1
Jacknin, G	1
Overbeck, MC	1
de Almeida, MC	1
Pederneiras, SG	1
Chiaroni, S	1
de Souza, L	1
Locks, GF	1
Fields, RG	1
Gencorelli, FJ	1
Litman, RS	1
Marsch, SC	1
Steiner, L	1
Bucher, E	1
Pargger, H	1
Schumann, M	1
Aebi, T	1
Hunziker, PR	1
Siegemund, M	1
Ochs, M	1
Davis, D	1
Hoyt, D	1
Bailey, D	1
Marshall, L	1
Rosen, P	1
BACSA, S	1
CZAKO, Z	1
ARANYOSI, J	1
BRUMLIK, J	1
MIER, M	1
PETROVICK, M	1
JENSEN, HP	1
NIXON, JC	1
THIEL, CJ	1
BERGER, J	1
KAPFHAMMER, V	1
KONTOS, HA	1
MAUCK, HP	1
RICHARDSON, DW	1
PATTERSON, JL	1
Watt, P	1
James, RH	1
Trinder, J	1
Nolan, RT	1
Chadwick, O	1
McCormick, AS	1
Saunders, DA	1
Xue, FS	1
Luo, LK	1
Tong, SY	1
Liao, X	1
Deng, XM	1
An, G	1
Bhavani-Shankar, K	1
Hart, NS	1
Mushlin, PS	1
Annis, JP	1
Khoo, ST	1
Woo, M	1
Kumar, A	1
Yaddanapudi, LN	1
Kashyap, L	1
Mallick, A	1
Gambee, AM	1
Hertzka, RE	1
Fisher, DM	1
Leiman, BC	1
Katz, J	1
Butler, BD	1
Millis, RM	1
Wood, DH	1
Trouth, CO	1
Felton, DJ	1
Goddard, BA	1
Scott, DB	1
Kerr, MG	1
Eyzaguirre, C	1
Zapata, P	1
Derom, R	1
Thiery, M	1
Rolly, G	1
Bolwig, TG	1
Fuglsang-Frederiksen, A	1
McGarry, P	1
Duncan, C	1
List, WF	1
Katz, RL	1
Bigger, JT	1
Hauenschild, E	1
Iriki, M	1
Pleschka, K	1
Walther, OE	1
Simon, E	1
Reske-Nielsen, E	1
Kratholm, S	1
Hayashi, T	1
Veragut, UP	1
Bailey, LL	1
Smith, LL	1
Linda, L	1
Loegering, DJ	1
Critz, JB	1
Britt, BA	1
Gordon, RA	1
Cullen, WG	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Phase 4 Study of Succinylcholine Versus Rocuronium as Neuromuscular Blocking Agent for Emergency Intubation in Intensive Care[NCT00355368]	Phase 4	420 participants (Actual)	Interventional	2006-08-31	Completed
EPO2-A: Evaluation of Different Pre-Oxygenation Condition in Morbid Obesity: Effect of Position and Positive Pressure Ventilation During General Anesthesia Induction[NCT02590406]		50 participants (Actual)	Interventional	2015-09-30	Completed
Preoxygenation With Optiflow™, a High Flow Nasal Cannula (HFNC), is Superior to Preoxygenation With Facemask in Morbidly Obese Patients Undergoing General Anesthesia[NCT03009877]		0 participants (Actual)	Interventional	2018-07-31	Withdrawn (stopped due to withdrawn prior to IRB approval)
Factors Determining End-tidal O2 Concentration in During Pre-oxygenation[NCT03395782]		120 participants (Actual)	Observational [Patient Registry]	2018-10-30	Completed
The Efficacy and Tolerability of Different Levels of Inspiratory Support and PEEP During Preoxygenation. A Randomized Controlled Trial.[NCT00922753]		20 participants (Actual)	Interventional	2007-02-28	Completed
Effect of the Duration of Pre-oxygenation (3 Minutes vs 6 Minutes) on Apnea Tolerance in Obese Patients (BMI> 30 kg / m2) During the Induction of General Anesthesia[NCT04699435]		200 participants (Anticipated)	Interventional	2021-01-13	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

decrease of >5% in oxygen saturation measured continuously using pulse oxymetry (NCT00355368)
Timeframe: at any time between the start of the intubation sequence and 2min after the completion of intubation

Number of Participants With an Failed First Intubation Attempts

Intervention	participants (Number)
Succinylcholine	73
Rocuronium	66

defined as either uncompleted intubation attempt within 90 sec or starting a second intubation attempt (NCT00355368)
Timeframe: within the first 90 sec following the start of induction

Quality of Intubation Conditions Using a Validated Score: Viby-Mogensen et al. Good Clinical Research Practice (GCRP) in Pharmacodynamic Studies of Neuromuscular Blocking Agents. Acta Anaesthesiol Scand 1996;40:59-74.

Intervention	participants (Number)
Succinylcholine	32
Rocuronium	36

"The factors laryngoscopy, vocal cords, and response to intubation are individually rated with a score from 1 (bad intubation conditions)to 3 (excellent intubation conditions)and the resulting three scores are summed up. The maximum score is thus 9 while the minimum score is 3.~Units: measure on a scale" (NCT00355368)
Timeframe: during laryngoscopy and the first minute after completion of intubation

Time to Completion of Intubation

Intervention	score points (Mean)
Succinylcholine	8.3
Rocuronium	8.2

time interval between the injection of the induction agent and the first appearance of endtidal CO2 (NCT00355368)
Timeframe: time interval between the injection of the induction agent and the first appearance of endtidal CO2

Maximum Expired Fraction of Oxygen Obtained

Intervention	seconds (Mean)
Succinylcholine	81
Rocuronium	95

Evaluation of the maximum expired oxygen fraction obtained in the two groups (NCT02590406)
Timeframe: After 3 minutes of pre-oxygenation

Minimum Arterial Saturation of Oxygen Obtained

Intervention	Maximum expired fraction of oxygen obtai (Mean)
Beach Chair (BC) and ZEEP	0.89
Reverse Trendelenburg and NIPPV	0.91

Evaluation of the minimal saturation obtained after the resumption of the ventilation (NCT02590406)
Timeframe: After the end of the Non-hypoxic apnea time

Non Hypoxic Apnea Time

Intervention	percent (Mean)
Beach Chair (BC) and ZEEP	83.6
Reverse Trendelenburg and NIPPV	85.3

Change of Non-hypoxic apnea time in obese patient during a General Anesthesia induction, as a result of different pre-oxygenation position and ventilation mode; 1-Beach Chair and No positive pressure ventilation, 2-Reverse Trendelenburg and positive pressure ventilation and PEEP. End of measure time frame is 5 minutes after intubation (NCT02590406)
Timeframe: After a 3 minutes pre-oxygenation period

Time to 97% Saturation

Intervention	seconds (Mean)
Beach Chair (BC) and ZEEP	216.7
Reverse Trendelenburg and NIPPV	258.2

(NCT02590406)
Timeframe: Evaluation of the time needed to the beginning of the ventilation to the moment where the saturation is 97%

Time to Expired Oxygen Fraction > 0,9

Intervention	seconds (Mean)
Beach Chair (BC) and ZEEP	88.4
Reverse Trendelenburg and NIPPV	68

Evaluation of time needed to obtain an expired fraction of oxygen of > 0,9 in the two groups during the pre-oxygenation (NCT02590406)
Timeframe: During the pre-oxygenation period

Article	Year
Airway and ventilator management. Emergency medicine clinics of North America, 1983, Volume: 1, Issue:2 Topics: Anesthesia; Emergencies; Emergency Medical Services; Gastroesophageal Reflux; Humans; Hypoxia; Inhal	1983
[Cardiac arrhythmias during anesthesia: their origin and pharmacological control]. Der Anaesthesist, 1966, Volume: 15, Issue:11 Topics: Anesthetics; Arrhythmias, Cardiac; Catecholamines; Digitalis Glycosides; Electroshock; Heart Disease	1966
Cardiac arrhythmias during anesthesia and operation. Anesthesiology, 1970, Volume: 33, Issue:2 Topics: Acidosis, Respiratory; Age Factors; Anesthesia; Anesthetics; Animals; Arrhythmia, Sinus; Arrhythmias	1970

Article	Year
[Evaluation of tracheal intubation conditions in morbidly obese patients: a comparison of succinylcholine and rocuronium]. Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:1 Topics: Adult; Androstanols; Body Weight; Cough; Diaphragm; Dose-Response Relationship, Drug; Female; Humans	2009
Succinylcholine versus rocuronium for rapid sequence intubation in intensive care: a prospective, randomized controlled trial. Critical care (London, England), 2011, Aug-16, Volume: 15, Issue:4 Topics: Adult; Aged; Androstanols; Female; Hospitals, University; Humans; Hypoxia; Intensive Care Units; Int	2011
Paramedic-performed rapid sequence intubation of patients with severe head injuries. Annals of emergency medicine, 2002, Volume: 40, Issue:2 Topics: Adult; Allied Health Personnel; Craniocerebral Trauma; Emergency Medical Services; Humans; Hypnotics	2002
Study of the safe threshold of apneic period in children during anesthesia induction. Journal of clinical anesthesia, 1996, Volume: 8, Issue:7 Topics: Age Factors; Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Body Height; Body Weight; Bra	1996
An assessment of preoxygenation techniques using the pulse oximeter. Annals of the Academy of Medicine, Singapore, 1992, Volume: 21, Issue:5 Topics: Adolescent; Adult; Child; Humans; Hypoxia; Intubation, Intratracheal; Middle Aged; Monitoring, Physi	1992

Article	Year
Incidence and factors associated with out-of-hospital peri-intubation cardiac arrest: a secondary analysis of the CURASMUR trial. Internal and emergency medicine, 2022, Volume: 17, Issue:2 Topics: Adult; Aged; Hospitals; Humans; Hypoxia; Incidence; Intubation, Intratracheal; Middle Aged; Out-of-H	2022
Peri-intubation factors affecting emergency physician choice of paralytic agent for rapid sequence intubation of trauma patients. The American journal of emergency medicine, 2018, Volume: 36, Issue:7 Topics: Adult; Choice Behavior; Clinical Decision-Making; Cluster Analysis; Emergency Treatment; Humans; Hyp	2018
Succinylcholine in an ED patient with unanticipated hyperkalemia. The American journal of emergency medicine, 2016, Volume: 34, Issue:10 Topics: Acute Kidney Injury; Emergency Service, Hospital; Humans; Hyperkalemia; Hypothyroidism; Hypoxia; Int	2016
Anesthetic management of the pediatric bleeding tonsil. Paediatric anaesthesia, 2010, Volume: 20, Issue:11 Topics: Adolescent; Anesthesia; Blood Loss, Surgical; Bradycardia; Child; Child, Preschool; Cohort Studies;	2010
[COMPLICATIONS OF ANESTHESIA OVER A 10-YEAR PERIOD]. Orvosi hetilap, 1963, Oct-20, Volume: 104 Topics: Acidosis; Anesthesia; Anesthesia, Endotracheal; Anesthesia, Local; Anesthesiology; Barbiturates; Cur	1963
[EXPERIMENTAL STUDIES ON A FORM OF RESTING TREMOR IN THE EXTREMITIES OF HEALTHY DOGS]. Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1964, Jan-30, Volume: 278 Topics: Apnea; Dogs; Electrocardiography; Electroencephalography; Electromyography; Extremities; Heart Arres	1964
APNEA DUE TO INHERITANCE OF ATYPICAL PSEUDOCHOLINESTERASE. Canadian Medical Association journal, 1964, May-09, Volume: 90 Topics: Abscess; Anesthesia; Anesthesia, General; Anesthesiology; Apnea; Butyrylcholinesterase; Cholinestera	1964
[CLINICAL PREOPERATIVE CARE IN GYNECOLOGY WITH SPECIAL REFERENCE TO PREPARATION, PERFORMANCE AND SAFETY OF ANESTHESIA. (POSTOPERATIVE MORTALITY STATISTICS 1943-1962)]. Gynaecologia. International monthly review of obstetrics and gynecology. Revue internationale mensuelle d'obstetrique et de gynecologie. Monatsschrift fur Geburtshilfe und Gynakologie, 1964, Volume: 157 Topics: Abortion, Therapeutic; Anesthesia; Anesthesia, Endotracheal; Curare; Female; Genital Neoplasms, Fema	1964
MECHANISM OF CIRCULATORY RESPONSES TO SYSTEMIC HYPOXIA IN THE ANESTHETIZED DOG. The American journal of physiology, 1965, Volume: 209 Topics: Blood Circulation; Blood Gas Analysis; Blood Pressure; Cardiac Output; Decamethonium Compounds; Dogs	1965
Prepreparation of succinylcholine. Anaesthesia, 2004, Volume: 59, Issue:8 Topics: Humans; Hypoxia; Laryngismus; Neuromuscular Depolarizing Agents; Succinylcholine	2004
Pre-oxygenation and thiopentone-suxamethonium induction. British journal of anaesthesia, 1967, Volume: 39, Issue:10 Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Endotracheal; Apnea; Carbon Dioxide; Female; Humans;	1967
Oxygen saturation of patients recovering from electroconvulsive therapy. Anaesthesia, 1996, Volume: 51, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Electroconvulsive Therapy; Female; Humans;	1996
Negative pressure induced airway and pulmonary injury. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:1 Topics: Adult; Ambulatory Surgical Procedures; Female; Hemoptysis; Humans; Hypoxia; Intraoperative Complicat	1997
Anesthesia for elective termination of pregnancy. JAMA, 1976, Dec-27, Volume: 236, Issue:26 Topics: Abortion, Induced; Anesthesia; Anesthesia, General; Female; Humans; Hypoxia; Pregnancy; Succinylchol	1976
Hypoxaemia and insertion of the laryngeal mask airway. British journal of anaesthesia, 1992, Volume: 69, Issue:6 Topics: Humans; Hypoxia; Laryngeal Masks; Respiration, Artificial; Succinylcholine	1992
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Preoxygenation techniques: comparison of three minutes and four breaths. Anesthesia and analgesia, 1987, Volume: 66, Issue:5 Topics: Anesthesia; Humans; Hypoxia; Intraoperative Complications; Oxygen; Oxygen Inhalation Therapy; Succin	1987
Mechanisms of succinylcholine-induced arrhythmias in hypoxic or hypoxic:hypercarbic dogs. Anesthesia and analgesia, 1987, Volume: 66, Issue:12 Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Dogs; Enflurane; Epinephrine; Halothane; Hype	1987
Amelioration of hypoxemia by neuromuscular blockade following brain injury. Life sciences, 1985, Aug-26, Volume: 37, Issue:8 Topics: Animals; Brain Injuries; Decerebrate State; Dogs; Hypoxia; Neuromuscular Blocking Agents; Pulmonary	1985
The effect of suxamethonium chloride on uterine activity. Lancet (London, England), 1966, Apr-16, Volume: 1, Issue:7442 Topics: Adult; Cesarean Section; Female; Humans; Hypoxia; Pregnancy; Succinylcholine; Uterine Diseases; Uter	1966
Suxamethonium and uterine activity. Lancet (London, England), 1966, May-14, Volume: 1, Issue:7446 Topics: Female; Humans; Hypoxia; Pregnancy; Succinylcholine; Uterus	1966
Pharmacology of pH effects on carotid body chemoreceptors in vitro. The Journal of physiology, 1968, Volume: 195, Issue:3 Topics: Acetylcholine; Acetylcholinesterase; Action Potentials; Animals; Atropine; Calcium; Carotid Body; Ca	1968
Effects of general anesthesia on the acid-base balance of the human fetus during elective caesarean section. Acta anaesthesiologica Belgica, 1974, Volume: 25, Issue:1 Topics: Acid-Base Equilibrium; Anesthesia, General; Anesthesia, Obstetrical; Cesarean Section; Female; Fetal	1974
Electrolytes in brain, liver, diaphragm, and blood after electroshock in rats. Acta psychiatrica Scandinavica, 1972, Volume: 48, Issue:5 Topics: Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Diaphragm; Electroshock; Female; Hypoxia; Live	1972
Anesthetic risks in sickle cell trait. Pediatrics, 1973, Volume: 51, Issue:3 Topics: Adolescent; Anemia, Sickle Cell; Anesthesia, General; Autopsy; Brain; Child; Child, Preschool; Death	1973
[Anaesthesia for caesarean section]. Der Anaesthesist, 1972, Volume: 21, Issue:1 Topics: Adult; Anesthesia, Epidural; Anesthesia, Inhalation; Anesthesia, Obstetrical; Barbiturates; Blood Pr	1972
Hypoxia and hypercapnia in asphyctic differentiation of regional sympathetic activity in the anesthetized rabbit. Pflugers Archiv : European journal of physiology, 1971, Volume: 328, Issue:2 Topics: Action Potentials; Anesthesia, Intravenous; Animals; Carbon Dioxide; Ear, External; Female; Heart Ra	1971
Malignant hyperthermia. A fatal case provoked by anaesthesia in asymptomatic encephalitis? Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:4 Topics: Acidosis; Anesthesia; Autopsy; Bicarbonates; Brain Edema; Central Nervous System; Child; Fever; Halo	1971
Circulatory effects of prolonged hypoxia in normal and hemorrhaged dogs. Archives of surgery (Chicago, Ill. : 1960), 1969, Volume: 99, Issue:5 Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Bradycardia; Cardiac Output; Dogs; El	1969
Effect of hypoxia and muscular activity on plasma enzyme levels in dogs. The American journal of physiology, 1971, Volume: 220, Issue:1 Topics: Animals; Aspartate Aminotransferases; Blood Pressure; Body Temperature; Carbon Dioxide; Creatine Kin	1971
Three cases of malignant hyperthermia with special consideration of management. Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:2 Topics: Acidosis; Adult; Anesthesia, Inhalation; Child, Preschool; Female; Fever; Halothane; Humans; Hyperka	1969
Malignant hyperpyrexia during general anaesthesia: a report of two cases. Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:5 Topics: Adult; Anesthesia, General; Bicarbonates; Child; Dextrans; Female; Fever; Humans; Hydrocortisone; Hy	1966

succinylcholine and Hypoxia