Page last updated: 2024-11-04

succinylcholine and Huntington Disease

succinylcholine has been researched along with Huntington Disease in 6 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research Excerpts

ExcerptRelevanceReference
"Juvenile Huntington's Disease (JHD) is an involuntary movement disorder that comprises both neurological and psychiatric symptoms."1.31Anaesthesia and juvenile Huntington's disease. ( Gupta, K; Leng, CP, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gupta, K1
Leng, CP1
Wells, D1
Costarino, A1
Gross, JB1
Bush, GH1
Gualandi, W2
Bonfanti, G1

Reviews

1 review available for succinylcholine and Huntington Disease

ArticleYear
Pharmacogenetics and anaesthesia.
    Proceedings of the Royal Society of Medicine, 1968, Volume: 61, Issue:2

    Topics: Anemia, Sickle Cell; Anesthetics; Animals; Barbiturates; Cholinesterases; Fever; Genetics, Medical;

1968

Other Studies

5 other studies available for succinylcholine and Huntington Disease

ArticleYear
Anaesthesia and juvenile Huntington's disease.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:1

    Topics: Anesthesia, General; Child; Female; Gastroscopy; Humans; Huntington Disease; Neuromuscular Depolariz

2000
Anaesthesia and Huntington's chorea.
    Anaesthesia and intensive care, 1979, Volume: 7, Issue:4

    Topics: Anesthesia, Intravenous; Humans; Huntington Disease; Male; Middle Aged; Neuromuscular Depolarizing A

1979
Patients with Huntington's chorea may respond normally to succinylcholine.
    Anesthesiology, 1985, Volume: 63, Issue:5

    Topics: Anesthesia; Humans; Huntington Disease; Intubation, Intratracheal; Male; Middle Aged; Succinylcholin

1985
[A case of prolonged apnea in Huntington's chorea].
    Acta anaesthesiologica, 1968, Volume: 19

    Topics: Anesthesia; Apnea; Female; Humans; Huntington Disease; Middle Aged; Succinylcholine; Surgical Proced

1968
[Cholinesterase and Huntington's chorea].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1971, Volume: 7, Issue:1

    Topics: Anesthesia; Apnea; Cholinesterases; Female; Humans; Huntington Disease; Middle Aged; Succinylcholine

1971