Page last updated: 2024-11-04

succinylcholine and Hemiplegia

succinylcholine has been researched along with Hemiplegia in 8 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Hemiplegia: Severe or complete loss of motor function on one side of the body. This condition is usually caused by BRAIN DISEASES that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, BRAIN STEM lesions; cervical SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; and other conditions may manifest as hemiplegia. The term hemiparesis (see PARESIS) refers to mild to moderate weakness involving one side of the body.

Research Excerpts

ExcerptRelevanceReference
"The effects of spinal cord transection and acidosis on succinylcholine (SCC)-induced hyperkalemia were studied in Sprague-Dawley rats."7.67Synergistic effect of acidosis and succinylcholine-induced hyperkalemia in spinal cord transected rats. ( Breivik, H; Greider, P; Jones, DJ; Koller, ME; Smith, RB, 1984)
"The effects of spinal cord transection and acidosis on succinylcholine (SCC)-induced hyperkalemia were studied in Sprague-Dawley rats."3.67Synergistic effect of acidosis and succinylcholine-induced hyperkalemia in spinal cord transected rats. ( Breivik, H; Greider, P; Jones, DJ; Koller, ME; Smith, RB, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pang, YL1
Tseng, FL1
Tsai, YC1
Liu, YC1
Rubio, E1
Rodríguez-Navarro, MA1
García-Muñoz, M1
Alonso, J1
Azar, I1
Koller, ME1
Breivik, H1
Greider, P1
Jones, DJ1
Smith, RB1
Iwatsuki, N1
Kuroda, N1
Amaha, K1
Iwatsuki, K1
Choudhoury, KJ1
Choudhoury, S1
Fiacchino, F1
Ariano, C1
Gemma, M1
Cerrato, D1
Cooperman, LH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-Blind, Randomized, Crossover Design Study To Compare The Rocuronium Reversal By Sugammadex To Succinylcholine For Electroconvulsive Therapy (ECT)[NCT03532178]Phase 244 participants (Actual)Interventional2019-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Recovery Time of T1 to 90% Baseline

The time of neuromuscular recovery from sugammadex 4mg/kg dose reversal rocuronium at 0.6 mg/kg compared with traditionally used succinylcholine in electroconvulsive therapy (ECT). (NCT03532178)
Timeframe: 30 minutes

Interventionminutes (Mean)
Muscle Relaxant #16.79
Muscle Relaxant #210.97

Number of Participants With Treatment or Emergent Adverse Events of the Drugs

To document the side-effect profiles of sugammadex reversal of rocuronium and succhinylcholine in the ECT patient population (NCT03532178)
Timeframe: 24 hours after the procedure

,
InterventionParticipants (Count of Participants)
NauseaMyalgiaHeadache
Rocuronium + Sugammadex117
Succinylcholine + Normal Saline329

Reviews

1 review available for succinylcholine and Hemiplegia

ArticleYear
The response of patients with neuromuscular disorders to muscle relaxants: a review.
    Anesthesiology, 1984, Volume: 61, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Curare; Hemiplegia; Humans; Hyperkalemia; Malignant Hyperthermia; Mul

1984

Other Studies

7 other studies available for succinylcholine and Hemiplegia

ArticleYear
Suxamethonium-induced hyperkalaemia in a patient with a normal potassium level before rapid-sequence intubation.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2006, Volume: 8, Issue:3

    Topics: Aged; Aged, 80 and over; Hemiplegia; Humans; Hyperkalemia; Intracranial Hemorrhage, Traumatic; Intub

2006
[Major ambulatory surgery in a patient with alternating hemiplegia of childhood].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:1

    Topics: Adolescent; Ambulatory Surgical Procedures; Androstanols; Anesthesia, Dental; Anesthesia, Intravenou

2008
Synergistic effect of acidosis and succinylcholine-induced hyperkalemia in spinal cord transected rats.
    Acta anaesthesiologica Scandinavica, 1984, Volume: 28, Issue:1

    Topics: Acidosis, Respiratory; Animals; Cholinesterase Inhibitors; Fluorenes; Hemiplegia; Hexamethonium Comp

1984
Succinylcholine-induced hyperkalemia in patients with ruptured cerebral aneurysms.
    Anesthesiology, 1980, Volume: 53, Issue:1

    Topics: Adult; Aged; Body Weight; Female; Hemiplegia; Humans; Hyperkalemia; Intracranial Aneurysm; Male; Mid

1980
Ventricular fibrillation in a normokalemic hemiplegic patient during induction of anesthesia.
    Middle East journal of anaesthesiology, 1990, Volume: 10, Issue:5

    Topics: Accidents, Traffic; Adult; Anesthesia; Hemiplegia; Humans; Male; Mandibular Fractures; Succinylcholi

1990
Abnormal responses to succinylcholine and pancuronium in a patient with hemiparesis.
    Italian journal of neurological sciences, 1990, Volume: 11, Issue:5

    Topics: Action Potentials; Aged; Brain Neoplasms; Electromyography; Hemiplegia; Humans; Male; Neuromuscular

1990
Succinylcholine-induced hyperkalemia in neuromuscular disease.
    JAMA, 1970, Sep-14, Volume: 213, Issue:11

    Topics: Anesthesia, General; Arrhythmias, Cardiac; Central Nervous System Diseases; Chlorides; Chronic Disea

1970