Page last updated: 2024-11-04

succinylcholine and Genetic Predisposition

succinylcholine has been researched along with Genetic Predisposition in 9 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Research Excerpts

ExcerptRelevanceReference
"We describe a child who developed a malignant hyperthermia-like syndrome after exposure to succinylcholine and halothane."3.75Malignant hyperthermia-like syndrome and carnitine palmitoyltransferase II deficiency with heterozygous R503C mutation. ( Hogan, KJ; Vladutiu, GD, 2009)
"In this article the pathophysiology of malignant hyperthermia, its signs, symptoms and treatment as well as safe anesthetic agents for individuals susceptible to malignant hyperthermia are discussed."2.42[Malignant hyperthermia]. ( Glahn, KP, 2003)
" The successful treatment is based on an early diagnosis, immediately interruption of triggering agents, intravenous administration of Dantrolene in sufficient dosage and starting of adequate symptomatic treatment."2.41[Malignant hyperthermia]. ( Ben Ammar, MS; Bouhajja, B; Haddad, F, 2002)
"Sporadic clinical episodes of malignant hyperthermia (MH) that develop during general anaesthesia (GA) have been reported in Singapore."1.46Malignant Hyperthermia and Ryanodine Receptor Type 1 Gene (RyR1) Mutation in a Family in Singapore. ( Lai, PS; Lee, DW; Lee, TL; Li, DW; Yong, RY, 2017)
"A positive DNA test indicates malignant hyperthermia susceptibility with "causative" mutations but discordance requires that negative DNA tests are confirmed with in vitro contracture test."1.31Suspected malignant hyperthermia reactions in New Zealand. ( Couchman, K; Langton, EE; Pollock, AN; Stowell, KM; Waddington, M, 2002)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Baye, JF1
Petry, NJ1
Jacobson, SL1
Moore, MM1
Tucker, B1
Shaaban, S1
Massmann, AK1
Clark, NM1
Schultz, AJ1
Li, DW1
Lai, PS1
Lee, DW1
Yong, RY1
Lee, TL1
Hogan, KJ1
Vladutiu, GD1
Pollock, AN1
Langton, EE1
Couchman, K1
Stowell, KM1
Waddington, M1
Bouhajja, B1
Haddad, F1
Ben Ammar, MS1
Glahn, KP1
Rosenberg, H1
Davis, M1
James, D1
Pollock, N1
Stowell, K1
Antel, JP1
Arnason, BG1
Cosgrove, SB1
Eisele, PH1
Martucci, RW1
Gronert, GA1

Reviews

4 reviews available for succinylcholine and Genetic Predisposition

ArticleYear
[Malignant hyperthermia].
    La Tunisie medicale, 2002, Volume: 80, Issue:7

    Topics: Anesthesia, General; Dantrolene; Diagnosis, Differential; Genetic Predisposition to Disease; Humans;

2002
[Malignant hyperthermia].
    Ugeskrift for laeger, 2003, Apr-21, Volume: 165, Issue:17

    Topics: Anesthetics, Inhalation; Dantrolene; Diagnosis, Differential; Genetic Predisposition to Disease; Hum

2003
Malignant hyperthermia.
    Orphanet journal of rare diseases, 2007, Apr-24, Volume: 2

    Topics: Adolescent; Adult; Aged; Animals; Child; Child, Preschool; Diagnosis, Differential; Female; Genetic

2007
Genetic predisposition to environmental factors.
    Research publications - Association for Research in Nervous and Mental Disease, 1983, Volume: 60

    Topics: Drug-Related Side Effects and Adverse Reactions; Environment; Genes, MHC Class II; Genetic Linkage;

1983

Other Studies

5 other studies available for succinylcholine and Genetic Predisposition

ArticleYear
Malignant hyperthermia susceptibility: utilization of genetic results in an electronic medical record to increase safety.
    Pharmacogenomics, 2020, Volume: 21, Issue:17

    Topics: Anesthetics, Inhalation; Calcium Channels, L-Type; Decision Support Systems, Clinical; Electronic He

2020
Malignant Hyperthermia and Ryanodine Receptor Type 1 Gene (RyR1) Mutation in a Family in Singapore.
    Annals of the Academy of Medicine, Singapore, 2017, Volume: 46, Issue:12

    Topics: Adult; Dantrolene; Female; Genetic Predisposition to Disease; Humans; Male; Malignant Hyperthermia;

2017
Malignant hyperthermia-like syndrome and carnitine palmitoyltransferase II deficiency with heterozygous R503C mutation.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:4

    Topics: Amino Acid Substitution; Anesthetics, Inhalation; Arginine; Carnitine O-Palmitoyltransferase; Child,

2009
Suspected malignant hyperthermia reactions in New Zealand.
    Anaesthesia and intensive care, 2002, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Anesthetics, Inhalation; Child; Child, Preschool; Female; Genetic Predisposition

2002
Evaluation of greyhound susceptibility to malignant hyperthermia using halothane-succinylcholine anesthesia and caffeine-halothane muscle contractures.
    Laboratory animal science, 1992, Volume: 42, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Caffeine; Disease Susceptibility; Dog Diseases; Dogs; Genetic Predi

1992