Page last updated: 2024-11-04

succinylcholine and Fasciculation

succinylcholine has been researched along with Fasciculation in 119 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Fasciculation: Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations may be visualized as a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)

Research Excerpts

ExcerptRelevanceReference
"The Authors report their clinical experience about the use of atracurium besylate in preventing succinylcholine-induced fasciculations and postoperative myalgias in fifty athletes (ASA class 1), submitted to arthroscopic meniscectomy."10.16[Use of atracurium for the prevention of fasciculations and succinylcholine myalgia in athletes undergoing orthopedic surgery]. ( Albertario, F; Dionigi, RV; Mora, R; Pagani, I; Ramaioli, F, 1990)
"This study evaluates the effect of pregabalin on fasciculation and myalgia after using succinylcholine."9.34The Effect of Pregabalin on the Prevention of Succinylcholine-Induced Fasciculation and Myalgia. ( Aghdashi, MM; Gholamveisi, B; Golabi, P; Haki, BK; Rajabzadeh, M; Sane, S, 2020)
"To compare the effects of different doses of cisatracurium pretreatment on succinylcholine-induced fasciculations."9.22Effects of pretreatment with different doses of cisatracurium on succinylcholine-induced fasciculations. ( Liu, XH; Sui, W; Sun, JH; Zhang, DS; Zhang, L; Zhang, Z, 2016)
"To investigate the effects of magnesium sulphate on succinylcholine-induced fasciculation in patients during the induction of general anaesthesia."9.19The effects of magnesium sulphate on succinylcholine-induced fasciculation during induction of general anaesthesia. ( Ahsan, B; Moradi, A; Rahimi, E; Rashadmanesh, N, 2014)
"The present visual and electromyographic study was designed to evaluate muscle fasciculations caused by succinylcholine in adults pretreated with either remifentanil 1."9.14Remifentanil attenuates muscle fasciculations by succinylcholine. ( Do, SH; Go, YK; Han, MK; Jung, WS; Kim, W; Kim, YH; Paik, NJ; Ryu, CG; Shin, JE; Yun, MJ, 2010)
"Several drugs have been used to prevent or attenuate succinylcholine- induced muscle fasciculations."9.14Comparison of atracurium and "mini-dose" succinylcholine for preventing succinylcholine-induced muscle fasciculations: a randomized, double-blind, placebo-controlled study. ( Fatemeh, H; Mojgan, R, 2010)
"To asses the effects of Rocuronium pretreatment on Succinylcholine induced Fasciculations and postoperative Myalgias."9.14To asses the effects of rocuronium pretreatment on succinylcholine induced fasciculations and postoperative myalgias. ( Abbas, N; Khan, AW; Khanzada, A; Murtaza, G; Naqvi, N; Tariq, S, 2009)
"Succinylcholine is a popular muscle relaxant and one of its most common side effects is muscle fasciculation."9.14Pretreatment with remifentanil is associated with less succinylcholine-induced fasciculation. ( Arastheh, MT; Nasseri, K; Shami, S, 2010)
"Succinylcholine is used during induction of anesthesia, and it may induce fasciculations."9.12Lidocaine or diazepam can decrease fasciculation induced by succinylcholine during induction of anesthesia. ( Hassani, M; Sahraian, MA, 2006)
"To determine the efficacy of rocuronium to prevent fasciculations and biochemical changes after succinylcholine administration."9.11[Precurarization with rocuronium prevents fasciculations and biochemical changes after succinylcholine administration]. ( Burguillos-López, S; Doménech-Asensi, P; Falcón-Araña, LF; Hernández-Palazón, J; Noguera-Velasco, J; Nuño de la Rosa-Carrillo, V, 2004)
"Fasciculations are a common side effect of the use of succinylcholine for tracheal intubation."9.10A comparison of tubocurarine, rocuronium, and cisatracurium in the prevention and reduction of succinylcholine-induced muscle fasciculations. ( Carter, PJ; True, CA, 2003)
"The purpose of this prospective study was to determine the effects of high-dose propofol on the incidence of fasciculations and myalgia, and to evaluate changes in creatine kinase levels following the administration of succinylcholine in 90 women who underwent laparoscopy."9.10Effects of high-dose propofol on succinylcholine-induced fasciculations and myalgia. ( Kararmaz, A; Kaya, S; Ozyilmaz, MA; Turhanoglu, S, 2003)
"The purpose of this study was to assess the effect of rocuronium pretreatment on the succinylcholine-induced fasciculations, myalgia and biochemical changes, and to compare it with vecuronium pretreatment."9.09Comparison of rocuronium and vecuronium pretreatment for prevention of fasciculations, myalgia and biochemical changes following succinylcholine administration. ( Chang, SH; Cho, H; Kim, JH; Lee, HW; Lim, HJ; Yoon, SM, 1999)
"To evaluate the efficacy of cisatracurium, rocuronium, and d-tubocurarine in preventing succinylcholine-induced fasciculations and postoperative myalgia in patients undergoing ambulatory surgery."9.09Effects of pretreatment with cisatracurium, rocuronium, and d-tubocurarine on succinylcholine-induced fasciculations and myalgia: a comparison with placebo. ( Cross, S; Hailey, A; Joshi, GP; Thompson-Bell, G; Whitten, CC, 1999)
"To determine which non-depolarizing relaxant among d-tubocurarine, vecuronium, atracurium, mivacurium and rocuronium prevented muscular fasciculations and myalgia following succinylcholine."9.08Rocuronium is the best non-depolarizing relaxant to prevent succinylcholine fasciculations and myalgia. ( Carrier, J; Claprood, Y; Martin, R; Pirlet, M; Tétrault, JP, 1998)
"5 min before succinylcholine administration on fasciculations, neuromuscular blockade and intubating conditions."9.08Rocuronium prevents succinylcholine-induced fasciculations. ( Choquette, R; Donati, F; Motamed, C, 1997)
"We compared d-tubocurarine and rocuronium for the prevention of succinylcholine-induced fasciculations and postoperative myalgia (POM) and evaluated the influence of both drugs on the speed of onset and recovery of succinylcholine."9.08Comparison of rocuronium and d-tubocurarine for prevention of succinylcholine-induced fasciculations and myalgia. ( Demers-Pelletier, J; Donati, F; Drolet, P; Girard, M, 1997)
"To determine the attenuation in the incidence of myalgia, fasciculations and changes in serum potassium and creatinine kinase concentrations when atracurium and lidocaine were used in combination and separately as pretreatment before succinylcholine."9.08Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment. ( Raman, SK; San, WM, 1997)
"The effect of alfentanil on suxamethonium-induced muscle fasciculations was studied in a double-blind study in 34 children (mean age 6."9.07Alfentanil inhibits muscle fasciculations caused by suxamethonium in children and in young adults. ( Lindgren, L; Randell, T; Varpula, T; Yli-Hankala, A, 1992)
"Prevention of fasciculations during rapid-sequence intubation of head trauma patients can be accomplished as safely and effectively with minidose succinylcholine as with a defasciculating dose of pancuronium."9.07Rapid-sequence intubation of head trauma patients: prevention of fasciculations with pancuronium versus minidose succinylcholine. ( Koenig, KL, 1992)
"The incidence and intensity of muscle fasciculations as well as the occurrence of cardiac arrhythmias following succinylcholine were evaluated in 36 premedicated children (1."9.07Isoflurane inhibits muscle fasciculations caused by succinylcholine in children. ( Lindgren, L; Randell, T; Yli-Hankala, A, 1993)
"01 mg kg-1, and fentanyl 1 or 2 micrograms kg-1 on the muscle fasciculations associated with suxamethonium were studied in 171 children undergoing otolaryngological surgery."9.05Effect of competitive myoneural blockade and fentanyl on muscle fasciculation caused by suxamethonium in children. ( Lindgren, L; Saarnivaara, L, 1983)
"To determine the effectiveness of diazepam pretreatment in preventing succinylcholine-induced fasciculations, 61 surgical patients were randomly allocated into three groups receiving either diazepam (0."9.05Does diazepam pretreatment prevent succinylcholine-induced fasciculations?--a double-blind comparison of diazepam and tubocurarine pretreatments. ( Erkola, O; Salmenperä, M; Tammisto, T, 1980)
"Single spike activity from the surface electromyogram (EMG) of fasciculations induced by succinylcholine (Sch) were studied from limb muscles (biceps, triceps, anterior tibialis and gastrocnemius) in 100 female patients."7.69EMG spike trains of succinylcholine-induced fasciculations in myalgic patients. ( Chan, FH; Chow, LH; Lam, FK; Lin, YM; Lui, PW; Poon, PW, 1996)
"The purpose of the study was to determine the effect of nondepolarizing muscle relaxants and waiting time on muscle fasciculations after succinylcholine in anaesthetized patients."7.69Waiting time after non-depolarizing relaxants alter muscle fasciculation response to succinylcholine. ( Patterson, L; Pinchak, AC; Shepard, LS; Smith, CE, 1994)
"During succinylcholine-induced muscle fasciculations, gastroesophageal barrier pressure in fasted adult dogs (n = 10) was compared by esophageal manometry with that in the same dogs with full stomachs."7.68Lower esophageal sphincter integrity is maintained during succinylcholine-induced fasciculations in dogs with "full" stomachs. ( Cook, WP; Schultetus, RR, 1990)
"To determine the effectiveness of diazepam pretreatment in preventing succinylcholine (SCh)-induced fasciculations and body pains, 587 patients were randomly allocated to six groups."7.67Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments. ( Manchikanti, L, 1984)
"02 mg X kg-1) on succinylcholine-induced fasciculations and myoglobinaemia was studied in 64 healthy children (ages two to nine years), anaesthetized with halothane, nitrous oxide and oxygen."7.67Succinylcholine, fasciculations and myoglobinaemia. ( Blanc, VF; Brisson, G; Vaillancourt, G, 1986)
"The efficacy of diazepam in attenuation of succinylcholine-induced muscle fasciculations was studied in the dog."7.66Effect of diazepam pretreatment on succinylcholine-induced muscle fasciculation in the dog. ( Crimi, AJ; Raffe, MR; Ruff, J, 1982)
"238 mg x kg-1, that is 2UD95 (UD95:unconsciousness dose 95) inhibit the intensity of succinylcholine-induced fasciculations compared with UD95."7.66The influence of thiopentone and alfathesin on succinylcholine-induced fasciculations and myalgias. ( Angel, A; Giron, GP; Manani, G; Meroni, M; Segatto, A; Valenti, S, 1981)
"The incidence of fasciculations was less in the atracurium pretreatment group (group B) than in the group treated with normal saline (group A)."6.68Evaluation of succinylcholine-induced fasciculations and myalgias with or without atracurium pretreatment. ( Hochhalter, CM, 1996)
"Muscle fasciculation and postoperative myalgia were verified by means of a score."6.66["Self-taming": an alternative to the prevention of succinylcholine-induced pain]. ( Doehn, M; Lohmann, C; Viell, B; Wald-Oboussier, G, 1987)
"In controls, the incidence of fasciculation was 95%, and the incidence of myalgia at 24 h was 50%."6.43Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials. ( Fuchs-Buder, T; Lysakowski, C; Schreiber, JU; Tramèr, MR, 2005)
"The Authors report their clinical experience about the use of atracurium besylate in preventing succinylcholine-induced fasciculations and postoperative myalgias in fifty athletes (ASA class 1), submitted to arthroscopic meniscectomy."6.16[Use of atracurium for the prevention of fasciculations and succinylcholine myalgia in athletes undergoing orthopedic surgery]. ( Albertario, F; Dionigi, RV; Mora, R; Pagani, I; Ramaioli, F, 1990)
"This study evaluates the effect of pregabalin on fasciculation and myalgia after using succinylcholine."5.34The Effect of Pregabalin on the Prevention of Succinylcholine-Induced Fasciculation and Myalgia. ( Aghdashi, MM; Gholamveisi, B; Golabi, P; Haki, BK; Rajabzadeh, M; Sane, S, 2020)
"The incidence and intensity of muscle fasciculations caused by suxamethonium were significantly greater in the control than in the alfentanil group."5.27Increase in intragastric pressure during suxamethonium-induced muscle fasciculations in children: inhibition by alfentanil. ( Lindgren, L; Saarnivaara, L, 1988)
"Pretreatment with rocuronium effectively reduces the biochemical changes associated with succinylcholine-induced muscle fasciculations."5.19Biochemical changes following succinylcholine administration after pretreatment with rocuronium at different intervals. ( Farhat, K; Jaffery, N; Pasha, AK, 2014)
"To investigate the effects of magnesium sulphate on succinylcholine-induced fasciculation in patients during the induction of general anaesthesia."5.19The effects of magnesium sulphate on succinylcholine-induced fasciculation during induction of general anaesthesia. ( Ahsan, B; Moradi, A; Rahimi, E; Rashadmanesh, N, 2014)
"To asses the effects of Rocuronium pretreatment on Succinylcholine induced Fasciculations and postoperative Myalgias."5.14To asses the effects of rocuronium pretreatment on succinylcholine induced fasciculations and postoperative myalgias. ( Abbas, N; Khan, AW; Khanzada, A; Murtaza, G; Naqvi, N; Tariq, S, 2009)
"Succinylcholine is a popular muscle relaxant and one of its most common side effects is muscle fasciculation."5.14Pretreatment with remifentanil is associated with less succinylcholine-induced fasciculation. ( Arastheh, MT; Nasseri, K; Shami, S, 2010)
"The present visual and electromyographic study was designed to evaluate muscle fasciculations caused by succinylcholine in adults pretreated with either remifentanil 1."5.14Remifentanil attenuates muscle fasciculations by succinylcholine. ( Do, SH; Go, YK; Han, MK; Jung, WS; Kim, W; Kim, YH; Paik, NJ; Ryu, CG; Shin, JE; Yun, MJ, 2010)
"To determine the effects of Magnesium-Sulphate-pretreatment on Suxamethonium-induced complications (serum potassium rise, fasciculations and apnea)."5.12The effects of magnesium sulphate-pretreatment on suxamethonium-induced complications during induction of general endotracheal anaesthesia. ( Danladi, KY; Eyelade, OR; Sotunmbi, PT, 2007)
"01 mg/kg cisatracurium in preventing succinylcholine-induced fasciculations and myalgia."5.10[Precurarization of succinylcholine with cisatracurium: the influence of the precurarization interval]. ( Becker, C; Bolte, M; Fuchs-Buder, T; Mencke, T; Schreiber, J, 2002)
"The purpose of this prospective study was to determine the effects of high-dose propofol on the incidence of fasciculations and myalgia, and to evaluate changes in creatine kinase levels following the administration of succinylcholine in 90 women who underwent laparoscopy."5.10Effects of high-dose propofol on succinylcholine-induced fasciculations and myalgia. ( Kararmaz, A; Kaya, S; Ozyilmaz, MA; Turhanoglu, S, 2003)
"To evaluate the efficacy of cisatracurium, rocuronium, and d-tubocurarine in preventing succinylcholine-induced fasciculations and postoperative myalgia in patients undergoing ambulatory surgery."5.09Effects of pretreatment with cisatracurium, rocuronium, and d-tubocurarine on succinylcholine-induced fasciculations and myalgia: a comparison with placebo. ( Cross, S; Hailey, A; Joshi, GP; Thompson-Bell, G; Whitten, CC, 1999)
"The purpose of this study was to assess the effect of rocuronium pretreatment on the succinylcholine-induced fasciculations, myalgia and biochemical changes, and to compare it with vecuronium pretreatment."5.09Comparison of rocuronium and vecuronium pretreatment for prevention of fasciculations, myalgia and biochemical changes following succinylcholine administration. ( Chang, SH; Cho, H; Kim, JH; Lee, HW; Lim, HJ; Yoon, SM, 1999)
"We compared d-tubocurarine and rocuronium for the prevention of succinylcholine-induced fasciculations and postoperative myalgia (POM) and evaluated the influence of both drugs on the speed of onset and recovery of succinylcholine."5.08Comparison of rocuronium and d-tubocurarine for prevention of succinylcholine-induced fasciculations and myalgia. ( Demers-Pelletier, J; Donati, F; Drolet, P; Girard, M, 1997)
"To determine which non-depolarizing relaxant among d-tubocurarine, vecuronium, atracurium, mivacurium and rocuronium prevented muscular fasciculations and myalgia following succinylcholine."5.08Rocuronium is the best non-depolarizing relaxant to prevent succinylcholine fasciculations and myalgia. ( Carrier, J; Claprood, Y; Martin, R; Pirlet, M; Tétrault, JP, 1998)
"01 mg/Kg), also noting intubation conditions and the presence or not of fasciculations after administration of succinylcholine (1."5.08[Electromyographic response to precurarization with vecuronium bromide]. ( Criado, A; de la Cruz, CA; Fraile, JR; López-Vidaur, P; Seiz, A, 1995)
"Rocuronium pretreatment given just before induction of anaesthesia with propofol reduces fasciculations and succinylcholine-induced myalgia."5.08A rapid precurarization technique using rocuronium. ( Finucane, B; Gupta, S; Kearney, R; Mayson, T; Reid, S; Tsui, BC, 1998)
"To determine the attenuation in the incidence of myalgia, fasciculations and changes in serum potassium and creatinine kinase concentrations when atracurium and lidocaine were used in combination and separately as pretreatment before succinylcholine."5.08Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment. ( Raman, SK; San, WM, 1997)
"The incidence and intensity of muscle fasciculations as well as the occurrence of cardiac arrhythmias following succinylcholine were evaluated in 36 premedicated children (1."5.07Isoflurane inhibits muscle fasciculations caused by succinylcholine in children. ( Lindgren, L; Randell, T; Yli-Hankala, A, 1993)
"Prevention of fasciculations during rapid-sequence intubation of head trauma patients can be accomplished as safely and effectively with minidose succinylcholine as with a defasciculating dose of pancuronium."5.07Rapid-sequence intubation of head trauma patients: prevention of fasciculations with pancuronium versus minidose succinylcholine. ( Koenig, KL, 1992)
"The effect of alfentanil on suxamethonium-induced muscle fasciculations was studied in a double-blind study in 34 children (mean age 6."5.07Alfentanil inhibits muscle fasciculations caused by suxamethonium in children and in young adults. ( Lindgren, L; Randell, T; Varpula, T; Yli-Hankala, A, 1992)
"A comparison was made of the incidence of postoperative myalgia (POM) and fasciculations when atracurium (ATR) or d-Tubocurarine (DTC) was given prior to succinylcholine (SDC) for facilitation of tracheal intubation."5.06Effectiveness of atracurium in preventing succinylcholine myalgia. ( Marr, AT; Sosis, M, 1989)
"We compared the incidence of postoperative myalgia (POM) and fasciculations when atracurium (ATR) or d-tubocurarine (DTC) was given prior to succinylcholine (SDC) for tracheal intubation in 44 ASA class I or II outpatient females undergoing laparoscopy."5.06Comparison of atracurium and d-tubocurarine for prevention of succinylcholine myalgia. ( Broad, T; Larijani, GE; Marr, AT; Sosis, M, 1987)
"To determine the effectiveness of diazepam pretreatment in preventing succinylcholine-induced fasciculations, 61 surgical patients were randomly allocated into three groups receiving either diazepam (0."5.05Does diazepam pretreatment prevent succinylcholine-induced fasciculations?--a double-blind comparison of diazepam and tubocurarine pretreatments. ( Erkola, O; Salmenperä, M; Tammisto, T, 1980)
"01 mg kg-1, and fentanyl 1 or 2 micrograms kg-1 on the muscle fasciculations associated with suxamethonium were studied in 171 children undergoing otolaryngological surgery."5.05Effect of competitive myoneural blockade and fentanyl on muscle fasciculation caused by suxamethonium in children. ( Lindgren, L; Saarnivaara, L, 1983)
"A single oral dose of dantrolene (100--150 mg) given at least 2 hr pre-operatively has been found to reduce significantly the strength of muscular fasciculations, the hyperkalaemia and the incidence of muscle pains following suxamethonium (from 56 to 4%) in a series of forty-eight patients compared with controls."5.04Dantrolene and suxamethonium. The effect of pre-operative dantrolene on the action of suxamethonium. ( Collier, CB, 1979)
"Single spike activity from the surface electromyogram (EMG) of fasciculations induced by succinylcholine (Sch) were studied from limb muscles (biceps, triceps, anterior tibialis and gastrocnemius) in 100 female patients."3.69EMG spike trains of succinylcholine-induced fasciculations in myalgic patients. ( Chan, FH; Chow, LH; Lam, FK; Lin, YM; Lui, PW; Poon, PW, 1996)
"The purpose of the study was to determine the effect of nondepolarizing muscle relaxants and waiting time on muscle fasciculations after succinylcholine in anaesthetized patients."3.69Waiting time after non-depolarizing relaxants alter muscle fasciculation response to succinylcholine. ( Patterson, L; Pinchak, AC; Shepard, LS; Smith, CE, 1994)
"Forty-four patients, ASA physical status I or II, undergoing thiamylal, fentanyl, N2O/O2 anaesthesia were studied to determine the dose-response to succinylcholine (Sch) without prior defasciculation (24 pt - Group 1), or three minutes following d-tubocurarine (dTC), 0."3.68A defasciculating dose of d-tubocurarine causes resistance to succinylcholine. ( Book, WJ; Eisenkraft, JB; Herlich, A; Kopman, AF; Mingus, ML, 1990)
"During succinylcholine-induced muscle fasciculations, gastroesophageal barrier pressure in fasted adult dogs (n = 10) was compared by esophageal manometry with that in the same dogs with full stomachs."3.68Lower esophageal sphincter integrity is maintained during succinylcholine-induced fasciculations in dogs with "full" stomachs. ( Cook, WP; Schultetus, RR, 1990)
"To determine the effectiveness of diazepam pretreatment in preventing succinylcholine (SCh)-induced fasciculations and body pains, 587 patients were randomly allocated to six groups."3.67Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments. ( Manchikanti, L, 1984)
"A study was conducted to determine the optimal interval between the administration of d-tubocurarine (dTc) and succinylcholine (SCh) with regard to onset and duration of neuromuscular block and presence of fasciculations and postoperative myalgias."3.67The search for an optimal interval between pretreatment dose of d-tubocurarine and succinylcholine. ( Horrow, JC; Lambert, DH, 1984)
"The effects of iv succinylcholine (SCh) on cerebral blood flow (CBF), muscle afferent activity (MAA), electromyographic activity (EMG), visible fasciculations, and PaCO2 were tested in 12 dogs anesthetized with 0."3.67Cerebral function and muscle afferent activity following intravenous succinylcholine in dogs anesthetized with halothane: the effects of pretreatment with a defasciculating dose of pancuronium. ( Iaizzo, PA; Lanier, WL; Milde, JH, 1989)
"02 mg X kg-1) on succinylcholine-induced fasciculations and myoglobinaemia was studied in 64 healthy children (ages two to nine years), anaesthetized with halothane, nitrous oxide and oxygen."3.67Succinylcholine, fasciculations and myoglobinaemia. ( Blanc, VF; Brisson, G; Vaillancourt, G, 1986)
"238 mg x kg-1, that is 2UD95 (UD95:unconsciousness dose 95) inhibit the intensity of succinylcholine-induced fasciculations compared with UD95."3.66The influence of thiopentone and alfathesin on succinylcholine-induced fasciculations and myalgias. ( Angel, A; Giron, GP; Manani, G; Meroni, M; Segatto, A; Valenti, S, 1981)
"The efficacy of diazepam in attenuation of succinylcholine-induced muscle fasciculations was studied in the dog."3.66Effect of diazepam pretreatment on succinylcholine-induced muscle fasciculation in the dog. ( Crimi, AJ; Raffe, MR; Ruff, J, 1982)
"Muscular fasciculations, plasma potassium levels and postoperative muscle pains following succinylcholine injection were studied in 64 patients who had been given either dilute flunitrazepam or sodium thiopental to induce anesthesia."3.66Intravenous flunitrazepam in the prevention of the side effects of succinylcholine. ( Aronson, HB; Vatashsky, E, 1982)
"The incidence and degree of fasciculation after succinylcholine administration were recorded."2.76Consequences of succinylcholine administration to patients using statins. ( Chu, W; Gottlieb, A; Gupta, S; Mendoza, ML; Saager, L; Sessler, DI; Turan, A; You, J, 2011)
"The results indicate that muscle fasciculation was not found in Group PR while the patients in Group LS had a lower incidence of muscle fasciculation than those in Group PS (p < 0."2.70Can lidocaine reduce succinylcholine induced postoperative myalgia? ( Amornyotin, S; Nilsuwankosit, P; Pipatnaraphong, H; Rachatamukayanant, P; Santawat, U, 2002)
"The incidence of fasciculations was significantly lower in the magnesium group."2.68Effects of magnesium sulphate on suxamethonium-induced complications during rapid-sequence induction of anaesthesia. ( Asai, T; Barclay, K; Stacey, MR; Vaughan, RS, 1995)
"The incidence of fasciculations was less in the atracurium pretreatment group (group B) than in the group treated with normal saline (group A)."2.68Evaluation of succinylcholine-induced fasciculations and myalgias with or without atracurium pretreatment. ( Hochhalter, CM, 1996)
"We studied the incidence of fasciculations and postoperative myalgias in 100 female outpatients who had laparoscopy under thiopentone, N2O, isoflurane anaesthesia."2.67Attenuation of suxamethonium myalgias. Effect of midazolam and vecuronium. ( Eisenkraft, JB; Herlich, A; Mingus, ML, 1990)
"Every pretreatment prevented fasciculations better than did saline (P less than 0."2.67Effects of precurarisation on suxamethonium-induced postoperative myalgia during the first trimester of pregnancy. ( Erkola, O, 1990)
"Both fasciculations and myalgia were assessed on a four-point rating scale."2.66Differential effects of neuromuscular blocking agents on suxamethonium-induced fasciculations and myalgia. ( Calvey, TN; O'Sullivan, EP; Williams, NE, 1988)
"Muscle fasciculations, intubating conditions, cardiovascular responses to endotracheal intubation and duration of neuromuscular block were assessed."2.66Optimal time interval between pretreatment with alcuronium and suxamethonium during anaesthetic induction. ( Klemola, UM; Lindgren, L; Saarnivaara, L, 1988)
"Muscle fasciculations and pain following the administration of suxamethonium were assessed in a group of patients who performed a series of stretch exercises approximately 1 h before operation."2.66Effect of stretch exercises on suxamethonium induced fasciculations and myalgia. ( Magee, DA; Robinson, RJ, 1987)
"Muscle fasciculation and postoperative myalgia were verified by means of a score."2.66["Self-taming": an alternative to the prevention of succinylcholine-induced pain]. ( Doehn, M; Lohmann, C; Viell, B; Wald-Oboussier, G, 1987)
"Total fasciculation score was not significantly reduced by the dantrolene pretreatment."2.66Oral dantrolene prevents rise of myoglobin due to suxamethonium. ( Laurence, AS, 1985)
"bolus dose."2.65Suxamethonium infusion rate and observed fasciculations. A dose-response study. ( Feingold, A; Velazquez, JL, 1979)
"In controls, the incidence of fasciculation was 95%, and the incidence of myalgia at 24 h was 50%."2.43Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials. ( Fuchs-Buder, T; Lysakowski, C; Schreiber, JU; Tramèr, MR, 2005)
"Intubation was performed after fasciculation."1.46Suxamethonium induces a prompt increase in the bispectral index. ( An, J; Choi, JB; Hong, S; Kim, JE; Kim, JY; Kim, YC; Lee, SY; Na, SH; Park, CH; Park, SY; Park, WY, 2017)
"The incidence and intensity of muscle fasciculations caused by suxamethonium were significantly greater in the control than in the alfentanil group."1.27Increase in intragastric pressure during suxamethonium-induced muscle fasciculations in children: inhibition by alfentanil. ( Lindgren, L; Saarnivaara, L, 1988)
"During muscle fasciculation serum potassium fell by 0."1.26Biphasic change in serum potassium concentration following a single dose of succinylcholine chloride. ( Etchin, A; Rothschild, C; Tverskoy, M; Zakut, H, 1981)
"Diazepam pretreatment prevented muscle fasciculations, increases in serum potassium (K+) and creatinine phosphokinase (CPK) levels, increased heart rate and arterial pressure, and postoperative myalgia associated with SCh administration."1.26Diazepam prevents some adverse effects of succinylcholine. ( Fahmy, NR; Lappas, DG; Malek, NS, 1979)
"The abolition of muscle fasciculations (by 0."1.26Post-suxamethonium pains in Nigerian surgical patients. ( Elegbe, EO; Famewo, CE, 1982)
"triceps) shows fasciculations in about 60% of cases and appears intimately associated with the development of suxamethonium pains, for if fasciculations do occur then suxamethonium pains are likely to ensure, but not necessarily involving all the fasciculating muscles."1.26Suxamethonium fasciculations: a topographical study. ( Collier, CB, 1980)

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-199054 (45.38)18.7374
1990's37 (31.09)18.2507
2000's13 (10.92)29.6817
2010's11 (9.24)24.3611
2020's4 (3.36)2.80

Authors

AuthorsStudies
Lanier, WL2
Sane, S2
Aghdashi, MM2
Haki, BK2
Gholamveisi, B2
Rajabzadeh, M2
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Abdulzahra, H1
Choi, JB1
Na, SH1
Lee, SY1
Kim, JY1
Park, SY1
Kim, JE1
Hong, S1
An, J1
Park, CH1
Kim, YC1
Park, WY1
Farhat, K1
Pasha, AK1
Jaffery, N1
Ahsan, B1
Rahimi, E1
Moradi, A1
Rashadmanesh, N1
Zhang, Z1
Zhang, DS1
Sui, W1
Liu, XH1
Zhang, L1
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Sellers, WF1
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Baraka, AS1
Haidar, YA1
Abdallah, FW1
Zbeidy, RA1
Siddik-Sayyid, SM1
Fatemeh, H1
Mojgan, R1
Yun, MJ1
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Shin, JE1
Ryu, CG1
Kim, W1
Paik, NJ1
Han, MK1
Do, SH1
Jung, WS1
Turan, A1
Mendoza, ML1
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You, J1
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Turner, MR1
Lawrence, H1
Arnold, I1
Ansorge, O1
Talbot, K1
Mencke, T2
Becker, C2
Schreiber, J1
Bolte, M2
Fuchs-Buder, T3
Amornyotin, S1
Santawat, U1
Rachatamukayanant, P1
Nilsuwankosit, P1
Pipatnaraphong, H1
Kararmaz, A1
Kaya, S1
Turhanoglu, S1
Ozyilmaz, MA1
True, CA1
Carter, PJ1
HARRISON, GA1
Hernández-Palazón, J1
Noguera-Velasco, J1
Falcón-Araña, LF1
Doménech-Asensi, P1
Burguillos-López, S1
Nuño de la Rosa-Carrillo, V1
Schreiber, JU2
Lysakowski, C1
Tramèr, MR1
Kettler, RE1
Sakuraba, S1
Serita, R1
Kosugi, S1
Eriksson, LI1
Lindahl, SG1
Takeda, J1
Hassani, M1
Sahraian, MA1
Danladi, KY1
Sotunmbi, PT1
Eyelade, OR1
Horrow, JC1
Lambert, DH1
Vatashsky, E1
Aronson, HB1
Muravchick, S1
Burkett, L1
Gold, MI1
Glasser, SA1
Courvoisier, C1
Forster, A1
Chastonay, PN1
Gemperlé, M1
Manchikanti, L1
Laveneziana, D1
Riva, A1
Zorzetto, C1
Tanoue, T1
Kano, T1
Marx, GF1
Bassell, GM1
Lindgren, L5
Saarnivaara, L3
Erkola, O3
Salmenperä, M1
Tammisto, T1
Durant, NN1
Katz, RL1
Collier, CB3
Raffe, MR1
Crimi, AJ1
Ruff, J1
Katre, AM1
Parab, SG1
Famewo, CE1
Elegbe, EO1
Manani, G1
Valenti, S1
Segatto, A1
Angel, A1
Meroni, M1
Giron, GP1
Viby-Mogensen, J1
Zakut, H1
Tverskoy, M1
Etchin, A1
Rothschild, C1
Popović, BM1
Restelli, L1
Miriano, F1
Pinciroli, D1
Movilia, P1
Friedman, S1
Baker, T1
Gatti, M1
Simon, G1
Paskin, S1
López-Vidaur, P1
Seiz, A1
de la Cruz, CA1
Fraile, JR1
Criado, A1
Pinchak, AC1
Smith, CE1
Shepard, LS1
Patterson, L1
McLoughlin, C1
Leslie, K1
Caldwell, JE1
Iaizzo, PA2
Wedel, DJ1
Nigrovic, V1
Wierda, JM1
Cannon, JE1
Stone, RJ1
Hinkle, AJ1
Dorsch, JA1
Maddineni, VR1
Mirakhur, RK1
Cooper, AR1
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Yli-Hankala, A2
Poon, PW1
Lui, PW1
Chow, LH1
Lam, FK1
Chan, FH1
Lin, YM1
Stacey, MR1
Barclay, K1
Asai, T1
Vaughan, RS1
Muiños, PA1
Ortells, MA1
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Carrasco, MS1
Hochhalter, CM1
Raman, SK1
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Demers-Pelletier, J1
Drolet, P1
Girard, M1
Donati, F2
Motamed, C1
Choquette, R1
Mizogami, M1
Fujibayashi, T1
Goto, Y1
Tsui, BC1
Reid, S1
Kearney, R1
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Lang, CC1
Wong, PK1
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Wang, CY1
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Kopman, AF2
Daley, MD1
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Chung, F1
Kim, JH1
Cho, H1
Lee, HW1
Lim, HJ1
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Joshi, GP1
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Laurence, AS2

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Precurarization With Rocuronium on the Incidence and Severity of Succinylcholine-Induced Fasciculations and Myalgias in a High Volume ERCP Center[NCT04581395]Phase 3300 participants (Actual)Interventional2020-10-02Completed
"A Less-rapid Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the Duration of Apnea Without Desaturation in Paralyzed Non-obese and Morbidly Obese Patients?"[NCT02943629]0 participants (Actual)Interventional2016-11-30Withdrawn (stopped due to Lack of feasibility)
A Double-Blind, Randomized, Crossover Design Study To Compare The Rocuronium Reversal By Sugammadex To Succinylcholine For Electroconvulsive Therapy (ECT)[NCT03532178]Phase 244 participants (Actual)Interventional2019-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Recovery Time of T1 to 90% Baseline

The time of neuromuscular recovery from sugammadex 4mg/kg dose reversal rocuronium at 0.6 mg/kg compared with traditionally used succinylcholine in electroconvulsive therapy (ECT). (NCT03532178)
Timeframe: 30 minutes

Interventionminutes (Mean)
Muscle Relaxant #16.79
Muscle Relaxant #210.97

Number of Participants With Treatment or Emergent Adverse Events of the Drugs

To document the side-effect profiles of sugammadex reversal of rocuronium and succhinylcholine in the ECT patient population (NCT03532178)
Timeframe: 24 hours after the procedure

,
InterventionParticipants (Count of Participants)
NauseaMyalgiaHeadache
Rocuronium + Sugammadex117
Succinylcholine + Normal Saline329

Reviews

4 reviews available for succinylcholine and Fasciculation

ArticleYear
Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials.
    Anesthesiology, 2005, Volume: 103, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Fasciculation; Humans; Li

2005
Suxamethonium.
    British journal of anaesthesia, 1982, Volume: 54, Issue:2

    Topics: Adult; Aging; Animals; Butyrylcholinesterase; Child; Dose-Response Relationship, Drug; Drug Interact

1982
Succinylcholine-associated postoperative myalgia.
    Anaesthesia, 2000, Volume: 55, Issue:2

    Topics: Fasciculation; Female; Humans; Male; Muscular Diseases; Neuromuscular Depolarizing Agents; Pain, Pos

2000
[Use of atracurium for the prevention of fasciculations and succinylcholine myalgia in athletes undergoing orthopedic surgery].
    Minerva anestesiologica, 1990, Volume: 56, Issue:11

    Topics: Adolescent; Adult; Atracurium; Fasciculation; Female; Humans; Male; Muscular Diseases; Orthopedics;

1990

Trials

55 trials available for succinylcholine and Fasciculation

ArticleYear
The Effect of Pregabalin on the Prevention of Succinylcholine-Induced Fasciculation and Myalgia.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2020, Volume: 35, Issue:3

    Topics: Adult; Double-Blind Method; Fasciculation; Humans; Middle Aged; Myalgia; Neuromuscular Depolarizing

2020
Biochemical changes following succinylcholine administration after pretreatment with rocuronium at different intervals.
    JPMA. The Journal of the Pakistan Medical Association, 2014, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Androstanols; Biomarkers; Creatine Kinase; Dose-Response Relationship, Drug; Drug

2014
The effects of magnesium sulphate on succinylcholine-induced fasciculation during induction of general anaesthesia.
    JPMA. The Journal of the Pakistan Medical Association, 2014, Volume: 64, Issue:10

    Topics: Adult; Anesthesia, General; Anticonvulsants; Double-Blind Method; Fasciculation; Female; Humans; Mag

2014
Effects of pretreatment with different doses of cisatracurium on succinylcholine-induced fasciculations.
    International journal of clinical pharmacology and therapeutics, 2016, Volume: 54, Issue:6

    Topics: Adult; Aged; Atracurium; Dose-Response Relationship, Drug; Double-Blind Method; Fasciculation; Femal

2016
To asses the effects of rocuronium pretreatment on succinylcholine induced fasciculations and postoperative myalgias.
    JPMA. The Journal of the Pakistan Medical Association, 2009, Volume: 59, Issue:12

    Topics: Adolescent; Adult; Androstanols; Double-Blind Method; Fasciculation; Female; Humans; Male; Middle Ag

2009
Pretreatment with remifentanil is associated with less succinylcholine-induced fasciculation.
    Middle East journal of anaesthesiology, 2010, Volume: 20, Issue:4

    Topics: Adult; Anesthesia, General; Anesthetics, Combined; Anesthetics, Intravenous; Bradycardia; Double-Bli

2010
Effect of suxamethonium vs rocuronium on onset of oxygen desaturation during apnoea following rapid sequence induction.
    Anaesthesia, 2010, Volume: 65, Issue:4

    Topics: Adult; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Fasci

2010
Comparison of atracurium and "mini-dose" succinylcholine for preventing succinylcholine-induced muscle fasciculations: a randomized, double-blind, placebo-controlled study.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2010, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Aged; Atracurium; Double-Blind Method; Fasciculation; Female; Humans; Male; Middl

2010
Remifentanil attenuates muscle fasciculations by succinylcholine.
    Yonsei medical journal, 2010, Volume: 51, Issue:4

    Topics: Adult; Aged; Blood Pressure; Creatine Kinase; Double-Blind Method; Electromyography; Fasciculation;

2010
Consequences of succinylcholine administration to patients using statins.
    Anesthesiology, 2011, Volume: 115, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, General; Anticholesteremic Agents; Creatine Kinase; Drug

2011
[Precurarization of succinylcholine with cisatracurium: the influence of the precurarization interval].
    Der Anaesthesist, 2002, Volume: 51, Issue:9

    Topics: Adult; Anesthesia; Atracurium; Fasciculation; Female; Humans; Male; Neuromuscular Depolarizing Agent

2002
Can lidocaine reduce succinylcholine induced postoperative myalgia?
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2002, Volume: 85 Suppl 3

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Androstanols; Anesthetics, Local; Chi-Square Distribu

2002
Effects of high-dose propofol on succinylcholine-induced fasciculations and myalgia.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:2

    Topics: Adult; Anesthetics, Intravenous; Creatine Kinase; Double-Blind Method; Fasciculation; Female; Gyneco

2003
A comparison of tubocurarine, rocuronium, and cisatracurium in the prevention and reduction of succinylcholine-induced muscle fasciculations.
    AANA journal, 2003, Volume: 71, Issue:1

    Topics: Adult; Androstanols; Atracurium; Fasciculation; Female; Humans; Male; Neuromuscular Nondepolarizing

2003
[Precurarization with rocuronium prevents fasciculations and biochemical changes after succinylcholine administration].
    Revista espanola de anestesiologia y reanimacion, 2004, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Androstanols; Double-Blind Method; Fasciculation; Female; Humans; Male; Middle Ag

2004
Pretreatment with magnesium sulphate is associated with less succinylcholine-induced fasciculation and subsequent tracheal intubation-induced hemodynamic changes than precurarization with vecuronium during rapid sequence induction.
    Acta anaesthesiologica Belgica, 2006, Volume: 57, Issue:3

    Topics: Adult; Aged; Anesthesia, General; Blood Pressure; Fasciculation; Female; Heart Rate; Humans; Intubat

2006
Lidocaine or diazepam can decrease fasciculation induced by succinylcholine during induction of anesthesia.
    Middle East journal of anaesthesiology, 2006, Volume: 18, Issue:5

    Topics: Adult; Anesthesia; Anesthetics, Intravenous; Anesthetics, Local; Blood Pressure; Diazepam; Elective

2006
The effects of magnesium sulphate-pretreatment on suxamethonium-induced complications during induction of general endotracheal anaesthesia.
    African journal of medicine and medical sciences, 2007, Volume: 36, Issue:1

    Topics: Adult; Anesthesia, General; Anesthetics; Apnea; Fasciculation; Female; Humans; Hyperkalemia; Intubat

2007
[Magnesium sulfate and pain caused by succinylcholine].
    Minerva anestesiologica, 1983, Volume: 49, Issue:12

    Topics: Adult; Aged; Fasciculation; Female; Humans; Magnesium Sulfate; Middle Aged; Muscles; Neurologic Mani

1983
Effect of competitive myoneural blockade and fentanyl on muscle fasciculation caused by suxamethonium in children.
    British journal of anaesthesia, 1983, Volume: 55, Issue:8

    Topics: Child; Child, Preschool; Fasciculation; Female; Fentanyl; Humans; Intraoperative Complications; Male

1983
Does diazepam pretreatment prevent succinylcholine-induced fasciculations?--a double-blind comparison of diazepam and tubocurarine pretreatments.
    Anesthesia and analgesia, 1980, Volume: 59, Issue:12

    Topics: Clinical Trials as Topic; Diazepam; Double-Blind Method; Fasciculation; Humans; Movement Disorders;

1980
[Electromyographic response to precurarization with vecuronium bromide].
    Revista espanola de anestesiologia y reanimacion, 1995, Volume: 42, Issue:2

    Topics: Adult; Aged; Electromyography; Fasciculation; Female; Humans; Male; Middle Aged; Succinylcholine; Ve

1995
Influence of dose on suxamethonium-induced muscle damage.
    British journal of anaesthesia, 1994, Volume: 73, Issue:2

    Topics: Adult; Ambulatory Surgical Procedures; Dose-Response Relationship, Drug; Fasciculation; Female; Huma

1994
Isoflurane inhibits muscle fasciculations caused by succinylcholine in children.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:3

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Arrhythmias, Cardiac; Child, Preschool; Fasciculati

1993
Effects of magnesium sulphate on suxamethonium-induced complications during rapid-sequence induction of anaesthesia.
    Anaesthesia, 1995, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anticonvulsants; Calcium; Double-Blind Method; Fascicu

1995
Evaluation of succinylcholine-induced fasciculations and myalgias with or without atracurium pretreatment.
    AANA journal, 1996, Volume: 64, Issue:4

    Topics: Adolescent; Adult; Aged; Atracurium; Double-Blind Method; Fasciculation; Female; Fibromyalgia; Human

1996
Fasciculations, myalgia and biochemical changes following succinylcholine with atracurium and lidocaine pretreatment.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:5 Pt 1

    Topics: Adult; Atracurium; Creatine Kinase; Double-Blind Method; Fasciculation; Female; Humans; Lidocaine; M

1997
Comparison of rocuronium and d-tubocurarine for prevention of succinylcholine-induced fasciculations and myalgia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:11

    Topics: Adolescent; Adult; Androstanols; Anesthesia, General; Electric Stimulation; Electromyography; Fascic

1997
Rocuronium prevents succinylcholine-induced fasciculations.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:12

    Topics: Adolescent; Adult; Aged; Androstanols; Double-Blind Method; Drug Combinations; Fasciculation; Female

1997
A rapid precurarization technique using rocuronium.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:5 Pt 1

    Topics: Adult; Androstanols; Double-Blind Method; Fasciculation; Humans; Neuromuscular Depolarizing Agents;

1998
The effect of mivacurium pretreatment on intra-ocular pressure changes induced by suxamethonium.
    Anaesthesia, 1998, Volume: 53, Issue:5

    Topics: Adolescent; Adult; Blood Pressure; Double-Blind Method; Fasciculation; Female; Humans; Intraocular P

1998
Rocuronium is the best non-depolarizing relaxant to prevent succinylcholine fasciculations and myalgia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:6

    Topics: Adult; Androstanols; Atracurium; Double-Blind Method; Fasciculation; Female; Follow-Up Studies; Huma

1998
A randomized, double-blind comparison of rocuronium, d-tubocurarine, and "mini-dose" succinylcholine for preventing succinylcholine-induced muscle fasciculations.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:3

    Topics: Adolescent; Adult; Aged; Androstanols; Anesthesia, General; Double-Blind Method; Fasciculation; Fema

1998
Comparison of rocuronium and vecuronium pretreatment for prevention of fasciculations, myalgia and biochemical changes following succinylcholine administration.
    Acta anaesthesiologica Sinica, 1999, Volume: 37, Issue:4

    Topics: Adult; Androstanols; Creatine Kinase; Double-Blind Method; Fasciculation; Female; Humans; Middle Age

1999
Effects of pretreatment with cisatracurium, rocuronium, and d-tubocurarine on succinylcholine-induced fasciculations and myalgia: a comparison with placebo.
    Journal of clinical anesthesia, 1999, Volume: 11, Issue:8

    Topics: Adult; Aged; Androstanols; Atracurium; Fasciculation; Female; Humans; Male; Middle Aged; Muscular Di

1999
Dantrolene and suxamethonium. The effect of pre-operative dantrolene on the action of suxamethonium.
    Anaesthesia, 1979, Volume: 34, Issue:2

    Topics: Adult; Clinical Trials as Topic; Dantrolene; Drug Interactions; Fasciculation; Female; Humans; Hydan

1979
Suxamethonium infusion rate and observed fasciculations. A dose-response study.
    British journal of anaesthesia, 1979, Volume: 51, Issue:3

    Topics: Dose-Response Relationship, Drug; Fasciculation; Humans; Infusions, Parenteral; Male; Middle Aged; M

1979
Prevention of suxamethonium-induced changes in serum potassium concentration by hexafluorenium. Is their combined use justified?
    British journal of anaesthesia, 1979, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Drug Synergism; Fasciculation; Female; Fluorenes; Hexamethonium Compounds; Humans

1979
Rapid-sequence intubation of head trauma patients: prevention of fasciculations with pancuronium versus minidose succinylcholine.
    Annals of emergency medicine, 1992, Volume: 21, Issue:8

    Topics: Adult; Craniocerebral Trauma; Double-Blind Method; Emergencies; Fasciculation; Humans; Intubation, I

1992
Alfentanil inhibits muscle fasciculations caused by suxamethonium in children and in young adults.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:6

    Topics: Adolescent; Adult; Alfentanil; Child; Child, Preschool; Double-Blind Method; Fasciculation; Female;

1992
Effects of precurarisation on suxamethonium-induced postoperative myalgia during the first trimester of pregnancy.
    Acta anaesthesiologica Scandinavica, 1990, Volume: 34, Issue:1

    Topics: Abortion, Induced; Adult; Alcuronium; Anesthesia, Inhalation; Anesthesia, Obstetrical; Atracurium; D

1990
Attenuation of suxamethonium myalgias. Effect of midazolam and vecuronium.
    Anaesthesia, 1990, Volume: 45, Issue:10

    Topics: Adult; Double-Blind Method; Fasciculation; Female; Humans; Midazolam; Muscular Diseases; Pain, Posto

1990
[Use of atracurium for the prevention of fasciculations and succinylcholine myalgia in athletes undergoing orthopedic surgery].
    Minerva anestesiologica, 1990, Volume: 56, Issue:11

    Topics: Adolescent; Adult; Atracurium; Fasciculation; Female; Humans; Male; Muscular Diseases; Orthopedics;

1990
Effectiveness of atracurium in preventing succinylcholine myalgia.
    AANA journal, 1989, Volume: 57, Issue:2

    Topics: Adolescent; Adult; Atracurium; Double-Blind Method; Fasciculation; Female; Humans; Intubation, Intra

1989
Comparison of atracurium and d-tubocurarine for prevention of succinylcholine myalgia.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:7

    Topics: Adolescent; Adult; Atracurium; Clinical Trials as Topic; Double-Blind Method; Fasciculation; Female;

1987
Effect of pre-treatment with lysine acetyl salicylate on suxamethonium-induced myalgia.
    British journal of anaesthesia, 1987, Volume: 59, Issue:5

    Topics: Adult; Analgesics; Aspirin; Double-Blind Method; Fasciculation; Female; Humans; Lysine; Muscular Dis

1987
Train-of-four fade of non depolarizing muscle relaxants: an insight into the mechanism of precurarization.
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Anesthesia, General; Electromyography; Fasciculation; Female; Humans; Male; Middl

1988
Differential effects of neuromuscular blocking agents on suxamethonium-induced fasciculations and myalgia.
    British journal of anaesthesia, 1988, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Fasciculation; Female; Human

1988
Optimal time interval between pretreatment with alcuronium and suxamethonium during anaesthetic induction.
    Acta anaesthesiologica Scandinavica, 1988, Volume: 32, Issue:3

    Topics: Adult; Alcuronium; Clinical Trials as Topic; Double-Blind Method; Fasciculation; Female; Hemodynamic

1988
Failure of lidocaine to modify suxamethonium induced biochemical changes.
    Middle East journal of anaesthesiology, 1988, Volume: 9, Issue:4

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Fasciculation; Female; Humans; Lidocaine; Pros

1988
Succinylcholine pretreatment with magnesium sulfate.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:4

    Topics: Adult; Anesthesia, Obstetrical; Cesarean Section; Clinical Trials as Topic; Drug Synergism; Fascicul

1986
[Does diazepam prevent fasciculation and myalgias caused by suxamethonium? A double-blind study].
    Ugeskrift for laeger, 1987, Feb-02, Volume: 149, Issue:6

    Topics: Clinical Trials as Topic; Diazepam; Double-Blind Method; Fasciculation; Female; Gallamine Triethiodi

1987
Effect of stretch exercises on suxamethonium induced fasciculations and myalgia.
    British journal of anaesthesia, 1987, Volume: 59, Issue:5

    Topics: Adult; Fasciculation; Female; Humans; Male; Muscular Diseases; Pain; Physical Exertion; Succinylchol

1987
["Self-taming": an alternative to the prevention of succinylcholine-induced pain].
    Der Anaesthesist, 1987, Volume: 36, Issue:8

    Topics: Adult; Anesthesia, General; Drug Administration Schedule; Fasciculation; Female; Humans; Male; Middl

1987
Oral dantrolene prevents rise of myoglobin due to suxamethonium.
    Anaesthesia, 1985, Volume: 40, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Creatine Kinase; Dantrolene; Drug Evaluation; Fasciculation

1985

Other Studies

61 other studies available for succinylcholine and Fasciculation

ArticleYear
Modulation of Cerebral Function by Muscle Afferent Activity, with Reference to Intravenous Succinylcholine.
    Anesthesiology, 2023, 02-01, Volume: 138, Issue:2

    Topics: Anesthesia; Animals; Dogs; Fasciculation; Halothane; Muscles; Succinylcholine

2023
Response to "The Effect of Pregabalin on the Prevention of Succinylcholine-Induced Fasciculation and Myalgia".
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2021, Volume: 36, Issue:2

    Topics: Fasciculation; Humans; Myalgia; Pain, Postoperative; Pregabalin; Succinylcholine

2021
Reply to Abdulzahra.
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2021, Volume: 36, Issue:2

    Topics: Fasciculation; Humans; Myalgia; Pregabalin; Succinylcholine

2021
Suxamethonium induces a prompt increase in the bispectral index.
    Medicine, 2017, Volume: 96, Issue:16

    Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Consciousness Monitors; Electroencephalography

2017
Fasciculations after succinylcholine and arterial oxygen tensions.
    British journal of anaesthesia, 2016, Volume: 116, Issue:5

    Topics: Apnea; Fasciculation; Humans; Oxygen; Rocuronium; Succinylcholine

2016
Catastrophic hyperkalaemia following administration of suxamethonium chloride to a patient with undiagnosed amyotrophic lateral sclerosis.
    Clinical medicine (London, England), 2011, Volume: 11, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Fasciculation; Fatal Outcome; Female; Humans; Hyperkalemia; Intubatio

2011
THE INCIDENCE OF VISIBLE MUSCULAR FASCICULATIONS FOLLOWING A SECOND DOSE OF SUXAMETHONIUM CHLORIDE.
    British journal of anaesthesia, 1965, Volume: 37

    Topics: Fasciculation; Geriatrics; Humans; Incidence; Muscle Contraction; Pharmacology; Succinylcholine

1965
Is the dose-related reduction in succinylcholine-induced myalgia due to cointervention?
    Anesthesiology, 2006, Volume: 105, Issue:1

    Topics: Fasciculation; Humans; Neuromuscular Depolarizing Agents; Succinylcholine

2006
The search for an optimal interval between pretreatment dose of d-tubocurarine and succinylcholine.
    Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:5

    Topics: Arthroscopy; Drug Administration Schedule; Fasciculation; Female; Genital Diseases, Female; Humans;

1984
Intravenous flunitrazepam in the prevention of the side effects of succinylcholine.
    Israel journal of medical sciences, 1982, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Fasciculation; Female; Flunitrazepam; Humans; Hyperkalemia;

1982
Succinylcholine-induce fasciculations and intragastric pressure during induction of anesthesia.
    Anesthesiology, 1981, Volume: 55, Issue:2

    Topics: Abdominal Muscles; Adult; Aged; Anesthesia, Intravenous; Electromyography; Fasciculation; Humans; In

1981
Violent fasciculations after small dose succinylcholine infusion as a first sign of atypical pseudocholinesterase.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:9

    Topics: Butyrylcholinesterase; Cholinesterases; Fasciculation; Female; Humans; Infusions, Parenteral; Intrao

1984
[Prevention of hyperkalemia and muscular fasciculations induced by suxamethonium].
    Annales francaises d'anesthesie et de reanimation, 1984, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Calcium Chloride; Fasciculation; Female; Humans; Hyperkalemia; Magnesium Sulfate;

1984
Diazepam does not prevent succinylcholine-induced fasciculations and myalgia. A comparative evaluation of the effect of diazepam and d-tubocurarine pretreatments.
    Acta anaesthesiologica Scandinavica, 1984, Volume: 28, Issue:5

    Topics: Anesthesia, General; Diazepam; Fasciculation; Humans; Muscular Diseases; Neurologic Manifestations;

1984
[Prevention of pre-relaxation fasciculation induced by succinylcholine chloride].
    Masui. The Japanese journal of anesthesiology, 1983, Volume: 32, Issue:3

    Topics: Adult; Anesthesia, Intravenous; Fasciculation; Female; Humans; Injections, Intravenous; Male; Middle

1983
In defense of the use of d-tubocurarine prior to succinylcholine in obstetrics.
    Anesthesiology, 1983, Volume: 59, Issue:2

    Topics: Anesthesia, Obstetrical; Fasciculation; Female; Humans; Pregnancy; Succinylcholine; Tubocurarine

1983
The recording of succinylcholine-induced fasciculations.
    Anesthesiology, 1982, Volume: 56, Issue:5

    Topics: Electromyography; Fasciculation; Humans; Neurologic Manifestations; Succinylcholine

1982
Effect of diazepam pretreatment on succinylcholine-induced muscle fasciculation in the dog.
    American journal of veterinary research, 1982, Volume: 43, Issue:3

    Topics: Animals; Diazepam; Dog Diseases; Dogs; Fasciculation; Female; Male; Neurologic Manifestations; Potas

1982
Post-operative muscle pain and serum potassium changes following self-taming of succinyl choline-induced fasciculations.
    Journal of postgraduate medicine, 1982, Volume: 28, Issue:1

    Topics: Fasciculation; Humans; Muscle Contraction; Neurologic Manifestations; Pain, Postoperative; Potassium

1982
Post-suxamethonium pains in Nigerian surgical patients.
    Middle East journal of anaesthesiology, 1982, Volume: 6, Issue:4

    Topics: Fasciculation; Female; Humans; Male; Nigeria; Pain; Succinylcholine

1982
The influence of thiopentone and alfathesin on succinylcholine-induced fasciculations and myalgias.
    Canadian Anaesthetists' Society journal, 1981, Volume: 28, Issue:3

    Topics: Adult; Alfaxalone Alfadolone Mixture; Dose-Response Relationship, Drug; Drug Interactions; Fascicula

1981
Succinylcholine neuromuscular blockade in subjects homozygous for atypical plasma cholinesterase.
    Anesthesiology, 1981, Volume: 55, Issue:4

    Topics: Adult; Aged; Cholinesterase Inhibitors; Cholinesterases; Fasciculation; Female; Homozygote; Humans;

1981
Biphasic change in serum potassium concentration following a single dose of succinylcholine chloride.
    Clinical and experimental obstetrics & gynecology, 1981, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Fasciculation; Female; Humans; Male; Middle Aged;

1981
[The effect of ketamine anesthesia induction on plasma potassium and fasciculations after the use of succinylcholine].
    Srpski arhiv za celokupno lekarstvo, 1981, Volume: 109, Issue:10

    Topics: Adult; Anesthesia, General; Fasciculation; Female; Humans; Ketamine; Male; Middle Aged; Neurologic M

1981
Suxamethonium fasciculations: a topographical study.
    Anaesthesia and intensive care, 1980, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Fasciculation; Female; Humans; Middle Aged; Movement Disorders; Muscles; Po

1980
[Muscular pains induced by suxamethonium. Prevention by use of self-taming dose (author's transl)].
    Anesthesie, analgesie, reanimation, 1980, Volume: 37, Issue:7-8

    Topics: Adult; Fasciculation; Humans; Muscular Diseases; Pain, Postoperative; Succinylcholine

1980
Probable succinylcholine-induced rhabdomyolysis in a male athlete.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:2

    Topics: Adolescent; Collateral Ligaments; Fasciculation; Football; Humans; Knee Injuries; Male; Myoglobinuri

1995
Waiting time after non-depolarizing relaxants alter muscle fasciculation response to succinylcholine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:3

    Topics: Adult; Atracurium; Cough; Fasciculation; Female; Humans; Incidence; Intubation, Intratracheal; Male;

1994
Response to succinylcholine in porcine malignant hyperthermia.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:1

    Topics: Action Potentials; Afferent Pathways; Animals; Carbon Dioxide; Catecholamines; Electromyography; Fas

1994
Post-succinylcholine muscle pain and smoking.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:5 Pt 1

    Topics: Adult; Anesthesia, Intravenous; Cohort Studies; Fasciculation; Female; Humans; Male; Muscular Diseas

1994
Precurarization.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:3

    Topics: Calcium; Electromyography; Fasciculation; Humans; Muscles; Neuromuscular Nondepolarizing Agents; Pai

1994
Suxamethonium in the deadspace of an adult's indwelling intravenous cannula.
    Anaesthesia, 1993, Volume: 48, Issue:9

    Topics: Adult; Apnea; Catheters, Indwelling; Fasciculation; Humans; Male; Respiratory Dead Space; Succinylch

1993
Maternal masseter muscle rigidity and neonatal fasciculations after induction for emergency cesarean section.
    Anesthesiology, 1993, Volume: 79, Issue:1

    Topics: Adult; Biopsy; Cesarean Section; Fasciculation; Female; Humans; Infant, Newborn; Infant, Premature,

1993
Myalgia and biochemical changes following suxamethonium after induction of anaesthesia with thiopentone or propofol.
    Anaesthesia, 1993, Volume: 48, Issue:7

    Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Creatine Kinase; Fasciculation; Female; Humans; Ma

1993
EMG spike trains of succinylcholine-induced fasciculations in myalgic patients.
    Electroencephalography and clinical neurophysiology, 1996, Volume: 101, Issue:3

    Topics: Action Potentials; Adult; Electromyography; Fasciculation; Female; Humans; Middle Aged; Muscle, Skel

1996
[A case of malignant hyperthermia without hyperthermia].
    Revista espanola de anestesiologia y reanimacion, 1995, Volume: 42, Issue:10

    Topics: Adolescent; Carbon Dioxide; Creatine Kinase; Dantrolene; Drug Eruptions; Fasciculation; Female; Huma

1995
Succinylcholine-induced fasciculations in denervated rat muscles as measured using 31P-NMR spectroscopy: the effect of pretreatment with dantrolene or vecuronium.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:4

    Topics: Animals; Calcium; Dantrolene; Fasciculation; Magnetic Resonance Spectroscopy; Male; Muscle Denervati

1998
Prevention of succinylcholine fasciculations.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:11

    Topics: Androstanols; Fasciculation; Humans; Muscular Diseases; Neuromuscular Depolarizing Agents; Neuromusc

1998
Prevention of succinylcholine fasciculations.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:11

    Topics: Androstanols; Atracurium; Fasciculation; Humans; Neuromuscular Blockade; Neuromuscular Depolarizing

1998
Prevention of succinylcholine fasciculations.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:11

    Topics: Androstanols; Fasciculation; Humans; Neuromuscular Depolarizing Agents; Neuromuscular Nondepolarizin

1998
Signs of an MH reaction.
    Paediatric anaesthesia, 1999, Volume: 9, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Atropine; Carbon Dioxide; Child; Fasciculation; Halo

1999
Pretreatment before succinylcholine for outpatient anesthesia?
    Anesthesia and analgesia, 2002, Volume: 94, Issue:3

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Androstanols; Anesthesia; Fasciculation; Female; Humans

2002
"Self-taming" of succinylcholine-induced fasciculations and intraocular pressure.
    Anesthesiology, 1979, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Fasciculation; Female; Glaucoma; Humans; Intraocular Pressure; Movement Disorders

1979
Does "self-taming" with succinylcholine prevent postoperative myalgia?
    Anesthesiology, 1979, Volume: 50, Issue:3

    Topics: Adult; Aged; Fasciculation; Female; Humans; Male; Middle Aged; Movement Disorders; Muscles; Pain, Po

1979
Relation of precurarization to suxamethonium to provide ease of intubation and to prevent post-suxamethonium muscle pains.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:2

    Topics: Adult; Body Weight; Fasciculation; Gallamine Triethiodide; Humans; Intubation, Intratracheal; Muscle

1979
Diazepam prevents some adverse effects of succinylcholine.
    Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Anesthesia; Creatine Kinase; Diazepam; Fasciculation; Female; Humans; Intubation,

1979
Neuromuscular pharmacology in rat neonates: development of responsiveness to prototypic blocking and reversal drugs.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:3

    Topics: 4-Aminopyridine; Aging; Animals; Animals, Newborn; Cholinesterase Inhibitors; Curare; Dose-Response

1992
Lower esophageal sphincter integrity is maintained during succinylcholine-induced fasciculations in dogs with "full" stomachs.
    Anesthesia and analgesia, 1990, Volume: 70, Issue:4

    Topics: Animals; Dogs; Esophagogastric Junction; Fasciculation; Manometry; Muscle Relaxation; Pressure; Stom

1990
A defasciculating dose of d-tubocurarine causes resistance to succinylcholine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:5

    Topics: Adult; Dose-Response Relationship, Drug; Drug Interactions; Fasciculation; Female; Humans; Male; Mid

1990
Cerebral function and muscle afferent activity following intravenous succinylcholine in dogs anesthetized with halothane: the effects of pretreatment with a defasciculating dose of pancuronium.
    Anesthesiology, 1989, Volume: 71, Issue:1

    Topics: Afferent Pathways; Animals; Blood Pressure; Brain; Cerebrovascular Circulation; Dogs; Drug Interacti

1989
"Statistical power" and interpretation of small studies: does atracurium pretreatment reduce the incidence of succinylcholine fasciculations?
    Anesthesia and analgesia, 1989, Volume: 69, Issue:2

    Topics: Atracurium; Fasciculation; Humans; Muscles; Pain; Research Design; Statistics as Topic; Succinylchol

1989
[Pretreatment dose of vecuronium and its effect on succinylcholine-induced fasciculations and neuromuscular blockade].
    Masui. The Japanese journal of anesthesiology, 1987, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Aged; Fasciculation; Female; Humans; Male; Middle Aged; Neuromuscular Junction; P

1987
Increase in intragastric pressure during suxamethonium-induced muscle fasciculations in children: inhibition by alfentanil.
    British journal of anaesthesia, 1988, Volume: 60, Issue:2

    Topics: Alfentanil; Analgesics; Child; Fasciculation; Female; Fentanyl; Humans; Male; Premedication; Pressur

1988
Atracurium pretreatment for prevention of succinylcholine fasciculations.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Atracurium; Fasciculation; Humans; Succinylcholine

1988
[Prevention of myalgia after intravenous administration of succinylcholine iodide].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1988, Volume: 67, Issue:2

    Topics: Anesthesia, General; Diazepam; Fasciculation; Humans; Injections, Intravenous; Muscles; Pain; Succin

1988
Influence of diazepam on the effects of suxamethonium.
    Journal of the Indian Medical Association, 1986, Volume: 84, Issue:9

    Topics: Adolescent; Adult; Anesthesia, Intravenous; Diazepam; Fasciculation; Female; Humans; Male; Middle Ag

1986
[Does diazepam prevent against suxamethonium-induced fasciculation and myalgia?].
    Ugeskrift for laeger, 1987, Mar-02, Volume: 149, Issue:10

    Topics: Diazepam; Fasciculation; Humans; Muscular Diseases; Pain; Succinylcholine

1987
Succinylcholine, fasciculations and myoglobinaemia.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:2

    Topics: Age Factors; Anesthesia, General; Child; Child, Preschool; Drug Administration Schedule; Fasciculati

1986
Violent fasciculations may not signal pseudocholinesterase deficiency.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:5

    Topics: Butyrylcholinesterase; Cholinesterases; Fasciculation; Humans; Neurologic Manifestations; Succinylch

1985
Failure of magnesium sulphate to prevent suxamethonium induced muscle pains.
    Anaesthesia, 1985, Volume: 40, Issue:5

    Topics: Early Ambulation; Fasciculation; Female; Humans; Magnesium Sulfate; Muscles; Pain, Postoperative; Pr

1985
Biochemical changes following suxamethonium. Serum myoglobin, potassium and creatinine kinase changes before commencement of surgery.
    Anaesthesia, 1985, Volume: 40, Issue:9

    Topics: Adolescent; Adult; Aged; Alcuronium; Creatine Kinase; Fasciculation; Female; Gallamine Triethiodide;

1985