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succinylcholine and Disease Models, Animal

succinylcholine has been researched along with Disease Models, Animal in 30 studies

Succinylcholine: A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
succinylcholine : A quaternary ammonium ion that is the bis-choline ester of succinic acid.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" Induction doses of ketamine 1 hour after HD exposure resulted in periods of profound apnea, with continued respiratory distress for the next 2 hours."3.70Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard. ( Conley, J; Hamilton, M; Hunter, K; Lundy, P; Sawyer, TW, 2000)
"Patients with myasthenia gravis (MG) have increased tolerance to the neuromuscular blocking properties of suxamethonium (SCh) and decamethonium (C10) and exhibit a reversal of the C10-induced block by neostigmine."3.66Neuromuscular blocking properties of suxamethonium and decamethonium in normal and myasthenic rat muscle. ( Johnson, BR; Kim, YI; Sanders, DB, 1983)
"The mitochondrial disturbance in Reye syndrome is well documented but the pathophysiologic sequence linking the antecedent viral illness to the mitochondrial injury remains obscure."2.37Reye syndrome. ( De Vivo, DC, 1985)
" Unfortunately, a variety of (sometimes lethal) adverse effects, such as hyperkalemia and cardiac arrest, are associated with its use, and currently there are no specific antidotes to reverse Sch or to treat these side-effects."1.51Supramolecular therapeutics to treat the side effects induced by a depolarizing neuromuscular blocking agent. ( Cheng, Q; Huang, F; Li, C; Li, L; Li, S; Shangguan, L; Wang, R; Zhang, J; Zhang, X, 2019)
"This situation may be similar to that in malignant hyperpyrexia (MH) occurring in mammals."1.26The chick as a model for malignant hyperpyrexia. ( Korczyn, AD; Shavit, S; Shlosberg, I, 1980)
"In this Research Conference we define malignant hyperthermia, present its brief history, and describe the diagnostic procedures and directions of research in our laboratory."1.26Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion. ( Flewellen, EH; Nelson, TE, 1979)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199018 (60.00)18.7374
1990's3 (10.00)18.2507
2000's2 (6.67)29.6817
2010's6 (20.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Zhang, X1
Cheng, Q1
Li, L1
Shangguan, L1
Li, C1
Li, S1
Huang, F1
Zhang, J1
Wang, R1
Martin-Flores, M1
Paré, MD1
Campoy, L1
Romano, M1
Tomak, EA1
Gleed, RD1
Waisman, D1
Lev-Tov, L1
Levy, C1
Faingersh, A1
Colman Klotzman, I1
Bibi, H1
Rotschild, A1
Landesberg, A1
Metterlein, T1
Schuster, F1
Kranke, P1
Hager, M1
Roewer, N1
Anetseder, M1
Cline, BH1
Steinbusch, HW1
Malin, D1
Revishchin, AV1
Pavlova, GV1
Cespuglio, R1
Strekalova, T1
Bozeman, WP1
Idris, AH1
Mayzner-Zawadzka, E1
Mitchell, G1
Heffron, JJ1
Johnson, BR1
Kim, YI1
Sanders, DB1
Hall, GM1
Lucke, JN1
Lister, D1
Claus-Walker, J1
Halstead, LS1
Korczyn, AD1
Shavit, S1
Shlosberg, I1
Fairhurst, AS1
Hamamoto, V1
Macri, J1
Rosenberg, H1
Fletcher, JE1
McBean, DE1
Kelly, PA1
Conley, J1
Hunter, K1
Lundy, P1
Hamilton, M1
Sawyer, TW1
Okumura, F1
Crocker, BD1
Denborough, MA1
Nelson, TE2
Flewellen, EH1
Korényi-Both, A1
Kelemen, G1
Moreno, RJ1
Kloess, P1
Carlson, DW1
De Vivo, DC1
Furniss, P1
Mettler, FA1
Sax, DS1
Bull, AB1
Harrison, GG1
Theye, RA1
Perry, LB1
Brzica, SM1
Jones, EW1
Anderson, IL1
Kerr, DD1
Burnap, TK1
Wasterlain, CG1
Stone, WA1
Beach, TP1
Hamelberg, W1

Reviews

5 reviews available for succinylcholine and Disease Models, Animal

ArticleYear
Porcine stress syndromes.
    Advances in food research, 1982, Volume: 28

    Topics: Animals; Disease Models, Animal; Drug Resistance; General Adaptation Syndrome; Glycolysis; Halothane

1982
Malignant hyperthermia--pearls out of swine?
    British journal of anaesthesia, 1980, Volume: 52, Issue:2

    Topics: Animals; Body Temperature; Dantrolene; Disease Models, Animal; Halothane; Magnesium Sulfate; Maligna

1980
An update on the malignant hyperthermia syndrome.
    Annals of the Academy of Medicine, Singapore, 1994, Volume: 23, Issue:6 Suppl

    Topics: Anesthetics; Animals; Calcium; Calcium Channels; Child; Dantrolene; Disease Models, Animal; Disease

1994
Rodent models of global cerebral ischemia: a comparison of two-vessel occlusion and four-vessel occlusion.
    General pharmacology, 1998, Volume: 30, Issue:4

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Humans; Intubation, Intratracheal; Neuromuscular De

1998
Reye syndrome.
    Neurologic clinics, 1985, Volume: 3, Issue:1

    Topics: Aflatoxins; Anesthesia, General; Animals; Child; Child, Preschool; Disease Models, Animal; Disease O

1985

Other Studies

25 other studies available for succinylcholine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Supramolecular therapeutics to treat the side effects induced by a depolarizing neuromuscular blocking agent.
    Theranostics, 2019, Volume: 9, Issue:11

    Topics: Animals; Antidotes; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Heart A

2019
The kalaemic and neuromuscular effects of succinylcholine in centronuclear myopathy: A pilot investigation in a canine model.
    European journal of anaesthesiology, 2015, Volume: 32, Issue:10

    Topics: Accelerometry; Animals; Disease Models, Animal; Dogs; Myopathies, Structural, Congenital; Neuromuscu

2015
Real-time detection, classification, and quantification of apneic episodes using miniature surface motion sensors in rats.
    Pediatric research, 2015, Volume: 78, Issue:1

    Topics: Animals; Blood Pressure; Disease Models, Animal; Heart Rate; Male; Monitoring, Physiologic; Motion;

2015
Magnesium does not influence the clinical course of succinylcholine-induced malignant hyperthermia.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:5

    Topics: Animals; Biomarkers; Carbon Dioxide; Disease Models, Animal; Energy Metabolism; Hemodynamics; Hydrog

2011
The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2.
    BMC neuroscience, 2012, Sep-18, Volume: 13

    Topics: Animals; Antidepressive Agents; Anxiety; Depression; Disease Models, Animal; Hippocampus; Imipramine

2012
Intracranial pressure changes during rapid sequence intubation: a swine model.
    The Journal of trauma, 2005, Volume: 58, Issue:2

    Topics: Animals; Brain Injuries; Cross-Over Studies; Disease Models, Animal; Emergency Treatment; Intracrani

2005
[Malignant hyperthermia in the pig--studies on the pathogenesis of the syndrome].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Jan-03, Volume: 38, Issue:1

    Topics: Animals; Basal Ganglia Diseases; Body Temperature Regulation; Carbon Dioxide; Disease Models, Animal

1983
Neuromuscular blocking properties of suxamethonium and decamethonium in normal and myasthenic rat muscle.
    Journal of the neurological sciences, 1983, Volume: 59, Issue:3

    Topics: Animals; Autoimmune Diseases; Decamethonium Compounds; Disease Models, Animal; Electrophysiology; Mo

1983
Metabolic and endocrine changes in spinal cord injury: I. The nervous system before and after transection of the spinal cord.
    Archives of physical medicine and rehabilitation, 1981, Volume: 62, Issue:12

    Topics: Animals; Disease Models, Animal; Dogs; Endocrine Glands; Humans; Nervous System Physiological Phenom

1981
The chick as a model for malignant hyperpyrexia.
    European journal of pharmacology, 1980, Jan-25, Volume: 61, Issue:2

    Topics: Animals; Calcium; Chickens; Dantrolene; Disease Models, Animal; Drug Evaluation, Preclinical; Malign

1980
Modification of ryanodine toxicity by dantrolene and halothane in a model of malignant hyperthermia.
    Anesthesiology, 1980, Volume: 53, Issue:3

    Topics: Alkaloids; Animals; Dantrolene; Diaphragm; Disease Models, Animal; Halothane; In Vitro Techniques; M

1980
Domestic swine model for the assessment of chemical warfare agent-anesthetic interactions: some effects of sulfur mustard.
    Military medicine, 2000, Volume: 165, Issue:8

    Topics: Anesthesia, General; Anesthetics; Animals; Apnea; Chemical Warfare; Disease Models, Animal; Drug Eva

2000
Identification of susceptibility to malignant hyperpyrexia in swine.
    British journal of anaesthesia, 1979, Volume: 51, Issue:3

    Topics: Animals; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; In Vitro Tec

1979
Malignant hyperthermia: diagnosis, treatment and investigations of a skeletal muscle lesion.
    Texas reports on biology and medicine, 1979, Volume: 38

    Topics: Anesthetics; Animals; Caffeine; Diagnosis, Differential; Disease Models, Animal; Halothane; Humans;

1979
Damage of skeletal muscle in rats by immunoglobulins. I. Pathophysiological data and lightmicroscopic observations.
    Acta neuropathologica, 1976, Mar-30, Volume: 34, Issue:3

    Topics: Animals; Autoimmune Diseases; Disease Models, Animal; Fatigue; Female; Immune Sera; Immunoglobulins;

1976
Effect of succinylcholine on the intraocular contents of open globes.
    Ophthalmology, 1991, Volume: 98, Issue:5

    Topics: Animals; Cats; Disease Models, Animal; Eye Injuries; Intraocular Pressure; Iris Diseases; Lens Sublu

1991
The etiology of malignant hyperpyrexia.
    Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:2

    Topics: Acidosis; Adenosine Triphosphatases; Age Factors; Anesthesia, General; Animals; Body Temperature Reg

1971
Cerebellar cortical degeneration due to acute azide poisoning.
    Brain : a journal of neurology, 1972, Volume: 95, Issue:3

    Topics: Animals; Azides; Cerebellar Ataxia; Cerebellar Cortex; Cerebral Decortication; Disease Models, Anima

1972
Recent advances in the understanding of anaesthetic-induced malignant hyperpyrexia.
    Acta anaesthesiologica Belgica, 1973, Volume: 24, Issue:2

    Topics: Acidosis; Anesthetics; Animals; Anura; Bicarbonates; Caffeine; Calcium; Cold Temperature; Disease Mo

1973
Influence of anesthetic agent on response to hemorrhagic hypotension.
    Anesthesiology, 1974, Volume: 40, Issue:1

    Topics: Adrenal Glands; Anesthesia, Inhalation; Anesthetics; Animals; Cyclopropanes; Disease Models, Animal;

1974
Malignant hyperthermia of swine.
    Anesthesiology, 1972, Volume: 36, Issue:1

    Topics: Adenosine Triphosphate; Adjuvants, Anesthesia; Anesthesia, Inhalation; Animals; Blood Pressure; Body

1972
Breakdown of brain polysomes in status epilepticus.
    Brain research, 1972, Apr-14, Volume: 39, Issue:1

    Topics: Animals; Brain; Disease Models, Animal; Electroencephalography; Electroshock; Epilepsy; Male; Nerve

1972
Succinylcholine-induced hyperkalemia in dogs with transected sciatic nerves or spinal cords.
    Anesthesiology, 1970, Volume: 32, Issue:6

    Topics: Animals; Central Nervous System; Central Nervous System Diseases; Disease Models, Animal; Dogs; Elec

1970